PCK2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description phosphoenolpyruvate carboxykinase 2 (mitochondrial)|This gene encodes a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of guanosine triphosphate (GTP). A cytosolic form of this protein is encoded by a different gene and is the key enzyme of gluconeogenesis in the liver. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2014] (NCBI Entrez Gene Database, 5106)
External Link https://ncbi.nlm.nih.gov/gene/5106
Similar Terms
Downloads & Tools

Genes

499 genes differentially expressed following the PCK2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.0198139
SIRT3 sirtuin 3 0.018699
MYBPC1 myosin binding protein C, slow type 0.0179135
SOX9 SRY (sex determining region Y)-box 9 0.0161119
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 0.0155105
LTF lactotransferrin 0.0154012
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.0153285
TM4SF1 transmembrane 4 L six family member 1 0.0152045
CLU clusterin 0.0148909
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.0145678
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.0135034
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.0133731
F5 coagulation factor V (proaccelerin, labile factor) 0.0129948
KRT15 keratin 15, type I 0.0128513
EREG epiregulin 0.0127451
ALCAM activated leukocyte cell adhesion molecule 0.0124875
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.0121731
IL1RN interleukin 1 receptor antagonist 0.0120635
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.0119654
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.0116565
CHI3L2 chitinase 3-like 2 0.0115084
CLIC3 chloride intracellular channel 3 0.0111171
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.011063
GPNMB glycoprotein (transmembrane) nmb 0.0110279
ADI1 acireductone dioxygenase 1 0.0108111
MET MET proto-oncogene, receptor tyrosine kinase 0.0107613
TAGLN2 transgelin 2 0.010696
FGFR3 fibroblast growth factor receptor 3 0.0106751
TIMP1 TIMP metallopeptidase inhibitor 1 0.0105962
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.0105875
CPB1 carboxypeptidase B1 (tissue) 0.0104023
PTN pleiotrophin 0.0103212
SPRR3 small proline-rich protein 3 0.0102869
TTN titin 0.0102829
SIK1 salt-inducible kinase 1 0.010226
DIPK1A divergent protein kinase domain 1A 0.0101181
PERP PERP, TP53 apoptosis effector 0.010097
MAGEA3 melanoma antigen family A3 0.0100181
GSDME gasdermin E 0.00996745
MSMB microseminoprotein, beta- 0.00982778
KRT14 keratin 14, type I 0.00982637
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.00979662
ZNF395 zinc finger protein 395 0.0097007
BLNK B-cell linker 0.00968846
TM4SF4 transmembrane 4 L six family member 4 0.00967184
GEM GTP binding protein overexpressed in skeletal muscle 0.00960341
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00957871
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 0.00957051
LYZ lysozyme 0.00953487
TRIB3 tribbles pseudokinase 3 0.00943611
VTCN1 V-set domain containing T cell activation inhibitor 1 0.0094286
TBL1X transducin (beta)-like 1X-linked 0.00940894
AK1 adenylate kinase 1 0.00935768
NT5DC2 5'-nucleotidase domain containing 2 0.00934754
FGG fibrinogen gamma chain 0.00928127
SYNM synemin, intermediate filament protein 0.00920348
HMGN3 high mobility group nucleosomal binding domain 3 0.00911428
C4BPA complement component 4 binding protein, alpha 0.00909043
PDGFC platelet derived growth factor C 0.00903705
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.00903321
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00902075
PRKCA protein kinase C, alpha 0.00893382
KLHL41 kelch-like family member 41 0.00887317
PKP1 plakophilin 1 0.00883598
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.00877398
GSAP gamma-secretase activating protein 0.0087721
PDE8B phosphodiesterase 8B 0.00875324
MAGEB2 melanoma antigen family B2 0.00869617
SCGB1D2 secretoglobin, family 1D, member 2 0.00855156
TLR4 toll-like receptor 4 0.00854845
ZNF750 zinc finger protein 750 0.00849632
GBAP1 glucosidase, beta, acid pseudogene 1 0.00849554
VASP vasodilator-stimulated phosphoprotein 0.00844329
PBX3 pre-B-cell leukemia homeobox 3 0.00844278
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.00841684
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.00841069
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.00839125
TPM2 tropomyosin 2 (beta) 0.0083706
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) 0.00831243
MMP7 matrix metallopeptidase 7 0.0082871
AREG amphiregulin 0.00825757
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.00824871
JUNB jun B proto-oncogene 0.00816878
SMCO4 single-pass membrane protein with coiled-coil domains 4 0.00815599
RAB13 RAB13, member RAS oncogene family 0.00814804
KRT18 keratin 18, type I 0.00814534
AQP9 aquaporin 9 0.00813058
BTG1 B-cell translocation gene 1, anti-proliferative 0.00812945
PSCA prostate stem cell antigen 0.00808869
KRT81 keratin 81, type II 0.0080842
CD52 CD52 molecule 0.0080516
TPD52L1 tumor protein D52-like 1 0.00804466
SHTN1 shootin 1 0.0080198
CTSH cathepsin H 0.00799471
CRCT1 cysteine-rich C-terminal 1 0.00793114
KRAS Kirsten rat sarcoma viral oncogene homolog 0.00792619
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 0.00788713
ADCY2 adenylate cyclase 2 (brain) 0.00785608
BGN biglycan 0.00783765
XIC X chromosome inactivation center 0.00783419
PLEK2 pleckstrin 2 0.00782452
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.00776653
MAOB monoamine oxidase B 0.00776107
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.00774699
SDC4 syndecan 4 0.00772821
GSTP1 glutathione S-transferase pi 1 0.0077043
RGCC regulator of cell cycle 0.00770246
MLF2 myeloid leukemia factor 2 0.007691
SLN sarcolipin 0.00765734
PELI1 pellino E3 ubiquitin protein ligase 1 0.00765376
ELF5 E74-like factor 5 (ets domain transcription factor) 0.00764931
ACSL1 acyl-CoA synthetase long-chain family member 1 0.00763206
TGM3 transglutaminase 3 0.00761759
KLHL21 kelch-like family member 21 0.00760966
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 0.00759514
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.00757399
HIST1H2BK histone cluster 1, H2bk 0.00756682
ALB albumin 0.0075651
FOXG1 forkhead box G1 0.00752158
ZBTB18 zinc finger and BTB domain containing 18 0.0075065
SPINK1 serine peptidase inhibitor, Kazal type 1 0.00750022
IGFBP6 insulin-like growth factor binding protein 6 0.00747732
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.0074669
SRPK2 SRSF protein kinase 2 0.00746244
SORBS2 sorbin and SH3 domain containing 2 0.00744555
TFF2 trefoil factor 2 0.0074358
H1-0 H1.0 linker histone 0.00743323
MMP9 matrix metallopeptidase 9 0.00742148
NMU neuromedin U 0.00741974
CRISP3 cysteine-rich secretory protein 3 0.00741735
HRASLS HRAS-like suppressor 0.00739565
NKX3-1 NK3 homeobox 1 0.00738295
CSTA cystatin A (stefin A) 0.00736456
WDTC1 WD and tetratricopeptide repeats 1 0.00732562
SHB Src homology 2 domain containing adaptor protein B 0.00731607
SSX1 synovial sarcoma, X breakpoint 1 0.00728626
CD40 CD40 molecule, TNF receptor superfamily member 5 0.00727798
CKM creatine kinase, muscle 0.00726838
CAV2 caveolin 2 0.00725703
ORM1 orosomucoid 1 0.0072351
ANXA10 annexin A10 0.00721439
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.00721377
SIM2 single-minded family bHLH transcription factor 2 0.00720627
PALLD palladin, cytoskeletal associated protein 0.00720198
MARCKSL1 MARCKS-like 1 0.00719973
ANO1 anoctamin 1, calcium activated chloride channel 0.00719317
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 0.00717979
MAGEA12 melanoma antigen family A12 0.0071751
C5AR1 complement component 5a receptor 1 0.00716895
NEBL nebulette 0.00716813
DLX5 distal-less homeobox 5 0.00715419
MYH2 myosin, heavy chain 2, skeletal muscle, adult 0.00712209
HSPB8 heat shock 22kDa protein 8 0.00712067
KAT2B K(lysine) acetyltransferase 2B 0.00711706
PPIB peptidylprolyl isomerase B (cyclophilin B) 0.00711353
TRPS1 trichorhinophalangeal syndrome I 0.00710263
SLCO4A1 solute carrier organic anion transporter family, member 4A1 0.00709893
ACTA1 actin, alpha 1, skeletal muscle 0.00707412
CD84 CD84 molecule 0.00705442
TRIM29 tripartite motif containing 29 0.00701223
PON3 paraoxonase 3 0.00700854
SRSF11 serine/arginine-rich splicing factor 11 0.0069746
CLDN10 claudin 10 0.0069608
VEGFC vascular endothelial growth factor C 0.00695085
BAG3 BCL2-associated athanogene 3 0.00693603
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00691362
ODC1 ornithine decarboxylase 1 0.00691245
TLR5 toll-like receptor 5 0.00689193
TUBA1A tubulin, alpha 1a 0.00689005
OMG oligodendrocyte myelin glycoprotein 0.00688889
SERTAD2 SERTA domain containing 2 0.00688705
SUSD5 sushi domain containing 5 0.0068767
STK26 serine/threonine protein kinase 26 0.00686318
GSTM3 glutathione S-transferase mu 3 (brain) 0.00682792
TNNI2 troponin I type 2 (skeletal, fast) 0.00680948
HSPA1A heat shock 70kDa protein 1A 0.00678961
CYRIA CYFIP related Rac1 interactor A 0.0067663
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.0067632
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase 0.0067531
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 0.00673949
MEIS2 Meis homeobox 2 0.00673176
COCH cochlin 0.00670813
SCN3A sodium channel, voltage gated, type III alpha subunit 0.00670195
GPRC5B G protein-coupled receptor, class C, group 5, member B 0.00670155
MTCL1 microtubule crosslinking factor 1 0.00668079
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor 0.00667454
TMEM131L transmembrane 131 like 0.00664682
ITGAV integrin, alpha V 0.00663891
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.00663745
FTH1 ferritin, heavy polypeptide 1 0.00663087
CNTN1 contactin 1 0.00661383
ORC1 origin recognition complex, subunit 1 0.00659405
CALR calreticulin 0.00658327
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 0.00657974
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 0.00655013
FGA fibrinogen alpha chain 0.00654716
KDM1A lysine (K)-specific demethylase 1A 0.00654338
KRT23 keratin 23, type I 0.0065315
CXCL5 chemokine (C-X-C motif) ligand 5 0.00652083
NOTCH2 notch 2 0.00651355
OFD1 oral-facial-digital syndrome 1 0.00651297
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00651193
C1QL1 complement component 1, q subcomponent-like 1 0.0064832
WNT5A wingless-type MMTV integration site family, member 5A 0.00647577
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 0.00646642
FBN2 fibrillin 2 0.00646323
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 0.00645922
DMTF1 cyclin D binding myb-like transcription factor 1 0.0064509
KYNU kynureninase 0.00644701
MBOAT2 membrane bound O-acyltransferase domain containing 2 0.0064056
CNN3 calponin 3, acidic 0.00639425
RIN2 Ras and Rab interactor 2 0.00638045
FAM189A2 family with sequence similarity 189, member A2 0.00638027
BICC1 BicC family RNA binding protein 1 0.00636644
NDRG2 NDRG family member 2 0.00636056
TFR2 transferrin receptor 2 0.00635832
RTN2 reticulon 2 0.00632931
CD82 CD82 molecule 0.00631519
FUCA1 fucosidase, alpha-L- 1, tissue 0.00629019
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2 0.0062797
FMO2 flavin containing monooxygenase 2 (non-functional) 0.00626743
KRT5 keratin 5, type II 0.00625863
NLRP2 NLR family, pyrin domain containing 2 0.00625821
PEG10 paternally expressed 10 0.00624125
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.00624116
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 0.00623792
AMIGO2 adhesion molecule with Ig-like domain 2 0.00623003
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 0.00620188
ARG2 arginase 2 0.00619732
SMS spermine synthase 0.00618865
LRRC23 leucine rich repeat containing 23 0.00618019
NAV2 neuron navigator 2 0.00615814
SALL1 spalt-like transcription factor 1 0.00615764
PDE4DIP phosphodiesterase 4D interacting protein 0.00615561
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00614851
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.00614502
ZNF532 zinc finger protein 532 0.00614137
TMSB15A thymosin beta 15a 0.00614132
ALOX5 arachidonate 5-lipoxygenase 0.00613314
TESC tescalcin 0.0061216
MLF1 myeloid leukemia factor 1 0.00611038
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.00611022
S100A3 S100 calcium binding protein A3 0.00610123
JADE3 jade family PHD finger 3 0.00609762
EXT1 exostosin glycosyltransferase 1 0.00609758
APOC1 apolipoprotein C-I 0.00609405
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.00609037
IGFBP1 insulin-like growth factor binding protein 1 0.00608571
USP47 ubiquitin specific peptidase 47 0.00607718

decreased expression

Symbol Name Standardized Value
CXCL14 chemokine (C-X-C motif) ligand 14 -0.0219797
CLEC2B C-type lectin domain family 2, member B -0.0180544
ASS1 argininosuccinate synthase 1 -0.0179377
PTGER4 prostaglandin E receptor 4 (subtype EP4) -0.0174456
ZG16 zymogen granule protein 16 -0.0149854
SST somatostatin -0.0146352
TXNDC9 thioredoxin domain containing 9 -0.0144933
THBS1 thrombospondin 1 -0.0143712
KRT20 keratin 20, type I -0.0142786
FABP1 fatty acid binding protein 1, liver -0.0142044
GPA33 glycoprotein A33 (transmembrane) -0.0135335
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.0134732
AQP3 aquaporin 3 (Gill blood group) -0.0134673
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -0.0133288
STMN2 stathmin 2 -0.0132677
IFITM1 interferon induced transmembrane protein 1 -0.0132111
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.0130555
LAMP5 lysosomal-associated membrane protein family, member 5 -0.0127866
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon -0.0127827
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -0.0127547
SPON1 spondin 1, extracellular matrix protein -0.0124858
CLCA4 chloride channel accessory 4 -0.0122878
NRN1 neuritin 1 -0.0121771
GREM1 gremlin 1, DAN family BMP antagonist -0.0121246
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 -0.0119079
FAR2 fatty acyl CoA reductase 2 -0.0117885
PITX3 paired-like homeodomain 3 -0.0115899
NVL nuclear VCP-like -0.0115548
CLCA1 chloride channel accessory 1 -0.0114264
CA4 carbonic anhydrase IV -0.0113849
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -0.0113709
CIAPIN1 cytokine induced apoptosis inhibitor 1 -0.0111512
COL15A1 collagen, type XV, alpha 1 -0.0109917
TOX3 TOX high mobility group box family member 3 -0.0108561
IGFBP5 insulin-like growth factor binding protein 5 -0.0106566
TFF3 trefoil factor 3 (intestinal) -0.0106145
CLIC5 chloride intracellular channel 5 -0.0104885
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 -0.0104619
HOXD1 homeobox D1 -0.010428
NELL2 NEL-like 2 (chicken) -0.0103116
MEP1A meprin A, alpha (PABA peptide hydrolase) -0.0101225
IFI27 interferon, alpha-inducible protein 27 -0.0100386
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B -0.00998073
CYTL1 cytokine-like 1 -0.00992242
SLC26A3 solute carrier family 26 (anion exchanger), member 3 -0.00985254
TGFBR3 transforming growth factor, beta receptor III -0.00983937
FABP4 fatty acid binding protein 4, adipocyte -0.00981134
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) -0.00978505
CD93 CD93 molecule -0.00970454
AOC1 amine oxidase, copper containing 1 -0.00968511
ITM2C integral membrane protein 2C -0.00962601
C6ORF48 chromosome 6 open reading frame 48 -0.00956695
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00956657
TSPAN7 tetraspanin 7 -0.00956578
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 -0.0095527
EMX2 empty spiracles homeobox 2 -0.00950075
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00949031
CHP2 calcineurin-like EF-hand protein 2 -0.00947564
TRIM36 tripartite motif containing 36 -0.00942442
LRRC19 leucine rich repeat containing 19 -0.00935053
GUCA2A guanylate cyclase activator 2A (guanylin) -0.00930302
GDE1 glycerophosphodiester phosphodiesterase 1 -0.0092988
HOXB7 homeobox B7 -0.00928197
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00923258
KIAA0100 KIAA0100 -0.00922426
SATB2 SATB homeobox 2 -0.00918626
AQP8 aquaporin 8 -0.0091848
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa -0.00914426
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00907197
OLFM4 olfactomedin 4 -0.00905703
SLC44A4 solute carrier family 44, member 4 -0.00904514
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -0.00902719
ASRGL1 asparaginase like 1 -0.00899292
MSRB2 methionine sulfoxide reductase B2 -0.0089737
CASP1 caspase 1, apoptosis-related cysteine peptidase -0.00892466
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog -0.0089173
MUC2 mucin 2, oligomeric mucus/gel-forming -0.0088745
FCGBP Fc fragment of IgG binding protein -0.00881958
MFAP5 microfibrillar associated protein 5 -0.00876468
RSAD2 radical S-adenosyl methionine domain containing 2 -0.00874102
GUCA2B guanylate cyclase activator 2B (uroguanylin) -0.00866423
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa -0.00864378
CHN2 chimerin 2 -0.00863577
CLEC11A C-type lectin domain family 11, member A -0.00862957
MAB21L2 mab-21-like 2 (C. elegans) -0.00852719
SYT1 synaptotagmin I -0.00851022
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.00849661
PRR5L proline rich 5 like -0.00847261
QPRT quinolinate phosphoribosyltransferase -0.00847003
AKR1C3 aldo-keto reductase family 1, member C3 -0.00846382
TMPRSS4 transmembrane protease, serine 4 -0.00845349
TRH thyrotropin-releasing hormone -0.00845326
CCNG1 cyclin G1 -0.00841809
ZBTB35 zinc finger and BTB domain containing 35 -0.00840242
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.00836559
STOM stomatin -0.00836203
MX2 MX dynamin-like GTPase 2 -0.00831229
KCTD12 potassium channel tetramerization domain containing 12 -0.00821701
CD177 CD177 molecule -0.00817719
MLXIP MLX interacting protein -0.0081545
FZD5 frizzled class receptor 5 -0.00811203
TDP1 tyrosyl-DNA phosphodiesterase 1 -0.00809398
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.0080911
MT1F metallothionein 1F -0.00807233
CHODL chondrolectin -0.00791691
COMP cartilage oligomeric matrix protein -0.00791311
CLDN7 claudin 7 -0.00788226
WT1 Wilms tumor 1 -0.00787095
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00786828
TRPM4 transient receptor potential cation channel, subfamily M, member 4 -0.007805
ACKR3 atypical chemokine receptor 3 -0.00779645
LEFTY1 left-right determination factor 1 -0.0077857
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -0.00778059
RPL26L1 ribosomal protein L26-like 1 -0.00777544
AMDHD2 amidohydrolase domain containing 2 -0.00776225
PGAM1 phosphoglycerate mutase 1 (brain) -0.0077516
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -0.00771806
ADIRF adipogenesis regulatory factor -0.00770919
ACAA2 acetyl-CoA acyltransferase 2 -0.0077079
TXN thioredoxin -0.00766357
AKAP12 A kinase (PRKA) anchor protein 12 -0.0076614
LIG1 ligase I, DNA, ATP-dependent -0.00765863
SNAP25 synaptosomal-associated protein, 25kDa -0.0076448
FAM46C family with sequence similarity 46, member C -0.00761632
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 -0.00757744
IGF1 insulin-like growth factor 1 (somatomedin C) -0.00757707
GMDS GDP-mannose 4,6-dehydratase -0.00756685
ECPAS Ecm29 proteasome adaptor and scaffold -0.0075665
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.00756004
CHGB chromogranin B -0.00755459
GCG glucagon -0.00754191
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.00753604
CLTB clathrin, light chain B -0.0075253
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -0.00752207
TFDP1 transcription factor Dp-1 -0.00749495
ESRP1 epithelial splicing regulatory protein 1 -0.00748762
TMEM126B transmembrane protein 126B -0.00747328
SLC38A2 solute carrier family 38, member 2 -0.00743249
IL2RG interleukin 2 receptor, gamma -0.00740511
CCL8 chemokine (C-C motif) ligand 8 -0.00740388
STK10 serine/threonine kinase 10 -0.00740357
MIS12 MIS12 kinetochore complex component -0.00739561
FASTKD5 FAST kinase domains 5 -0.00739453
ARMT1 acidic residue methyltransferase 1 -0.00737741
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A -0.00737671
RNF138 ring finger protein 138, E3 ubiquitin protein ligase -0.00737435
PYCARD PYD and CARD domain containing -0.00737175
ITGA6 integrin, alpha 6 -0.00734651
RB1 retinoblastoma 1 -0.00734571
RNH1 ribonuclease/angiogenin inhibitor 1 -0.00733875
BACE2 beta-site APP-cleaving enzyme 2 -0.00733509
HLA-DRA major histocompatibility complex, class II, DR alpha -0.00732437
IFI44L interferon-induced protein 44-like -0.00731752
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial -0.00731187
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -0.00730497
EPHB2 EPH receptor B2 -0.00729798
C4ORF19 chromosome 4 open reading frame 19 -0.0072578
NAAA N-acylethanolamine acid amidase -0.00725711
TMEM47 transmembrane protein 47 -0.00722195
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 -0.00721
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.00719982
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 -0.00719407
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -0.0071311
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00710367
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 -0.00708612
CDHR1 cadherin-related family member 1 -0.00702692
ARID5B AT rich interactive domain 5B (MRF1-like) -0.00701407
PPARG peroxisome proliferator-activated receptor gamma -0.00700495
PCCB propionyl CoA carboxylase, beta polypeptide -0.00700193
MMP3 matrix metallopeptidase 3 -0.00699527
MT1M metallothionein 1M -0.00699351
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.00697744
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 -0.00696364
OASL 2'-5'-oligoadenylate synthetase-like -0.00693427
CCL5 chemokine (C-C motif) ligand 5 -0.00692319
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00691595
ETHE1 ethylmalonic encephalopathy 1 -0.00690624
CXADR coxsackie virus and adenovirus receptor -0.00688931
DDAH2 dimethylarginine dimethylaminohydrolase 2 -0.00688312
SI sucrase-isomaltase (alpha-glucosidase) -0.00688084
LOX lysyl oxidase -0.00687412
MECOM MDS1 and EVI1 complex locus -0.0068703
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.00685658
RFK riboflavin kinase -0.00683775
ASF1A anti-silencing function 1A histone chaperone -0.00679767
COG7 component of oligomeric golgi complex 7 -0.00678994
MYH11 myosin, heavy chain 11, smooth muscle -0.00677984
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 -0.00675819
TCF21 transcription factor 21 -0.00673066
PLAT plasminogen activator, tissue -0.00672934
MUC4 mucin 4, cell surface associated -0.00671714
MMP1 matrix metallopeptidase 1 -0.00671427
PTCH1 patched 1 -0.00671118
RNF130 ring finger protein 130 -0.0066846
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -0.00668332
ADAMDEC1 ADAM-like, decysin 1 -0.00667876
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) -0.00667375
CCN2 cellular communication network factor 2 -0.00667316
PKP2 plakophilin 2 -0.00666692
REEP5 receptor accessory protein 5 -0.00665748
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -0.00663898
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene) -0.00663796
PTGER3 prostaglandin E receptor 3 (subtype EP3) -0.00662954
FAM162A family with sequence similarity 162, member A -0.00662431
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) -0.00661638
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -0.00659291
LGALS1 lectin, galactoside-binding, soluble, 1 -0.00658988
TMEM230 transmembrane protein 230 -0.00658538
PLSCR4 phospholipid scramblase 4 -0.00658481
NXPE4 neurexophilin and PC-esterase domain family, member 4 -0.00657835
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 -0.00657241
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00656295
IGFBP4 insulin-like growth factor binding protein 4 -0.00654414
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.00654284
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G -0.006541
OLFM1 olfactomedin 1 -0.00653542
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -0.00650742
MAN1A1 mannosidase, alpha, class 1A, member 1 -0.00649596
LIPT1 lipoyltransferase 1 -0.00649101
CXCR4 chemokine (C-X-C motif) receptor 4 -0.00648255
SKAP2 src kinase associated phosphoprotein 2 -0.00647436
CARHSP1 calcium regulated heat stable protein 1, 24kDa -0.0064561
SOX17 SRY (sex determining region Y)-box 17 -0.00645138
SFRP4 secreted frizzled-related protein 4 -0.0064322
MARCKS myristoylated alanine-rich protein kinase C substrate -0.00642191
BPHL biphenyl hydrolase-like (serine hydrolase) -0.00642121
CTSS cathepsin S -0.00641333
BTNL8 butyrophilin-like 8 -0.00641209
ITSN1 intersectin 1 (SH3 domain protein) -0.00640589
CD96 CD96 molecule -0.0063982
HPGDS hematopoietic prostaglandin D synthase -0.00638006
GPM6B glycoprotein M6B -0.00637404
WFDC1 WAP four-disulfide core domain 1 -0.00637199
NPR1 natriuretic peptide receptor 1 -0.00631705
PURA purine-rich element binding protein A -0.00631533
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) -0.00630783
CNIH4 cornichon family AMPA receptor auxiliary protein 4 -0.00630567
CLDN3 claudin 3 -0.00626336
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A -0.00625023
ANK2 ankyrin 2, neuronal -0.00624769
CD48 CD48 molecule -0.00624122
MRPL22 mitochondrial ribosomal protein L22 -0.0062349
TPBG trophoblast glycoprotein -0.00622652
NSG1 neuron specific gene family member 1 -0.00618444
CD3D CD3d molecule, delta (CD3-TCR complex) -0.00618073
SEC23A Sec23 homolog A (S. cerevisiae) -0.00617648
ADIPOQ adiponectin, C1Q and collagen domain containing -0.00616474
TSPAN13 tetraspanin 13 -0.00616355
BDH2 3-hydroxybutyrate dehydrogenase, type 2 -0.00616139
PROM1 prominin 1 -0.00615912