PCYT1A Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description phosphate cytidylyltransferase 1, choline, alpha| (NCBI Entrez Gene Database, 5130)
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Genes

356 genes differentially expressed following the PCYT1A gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
SCN2A sodium channel, voltage gated, type II alpha subunit 2.26376
SPI1 Spi-1 proto-oncogene 2.26376
LTBP2 latent transforming growth factor beta binding protein 2 2.26376
PDCL2 phosducin-like 2 2.26376
CFAP54 cilia and flagella associated 54 2.26376
FNDC1 fibronectin type III domain containing 1 2.26376
TMEM221 transmembrane protein 221 2.26376
SCN10A sodium channel, voltage gated, type X alpha subunit 2.26376
CCDC183 coiled-coil domain containing 183 2.26376
MAB21L3 mab-21-like 3 (C. elegans) 2.26376
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 2.26376
CALHM2 calcium homeostasis modulator 2 2.26376
BTC betacellulin 2.26376
DUSP15 dual specificity phosphatase 15 2.26376
PCDHB12 protocadherin beta 12 2.26376
P2RY8 purinergic receptor P2Y, G-protein coupled, 8 2.26376
TMEM272 transmembrane protein 272 2.26376
NAP1L5 nucleosome assembly protein 1-like 5 2.26376
ADRA2A adrenoceptor alpha 2A 2.26376
NUTM2G NUT family member 2G 2.26376
BCO1 beta-carotene oxygenase 1 2.26376
MYO16 myosin XVI 2.26376
GSG1 germ cell associated 1 2.26376
PENK proenkephalin 2.26376
RHOXF2 Rhox homeobox family, member 2 2.26376
CXORF58 chromosome X open reading frame 58 2.26376
FOXI3 forkhead box I3 2.2203
PDCL3 phosducin-like 3 2.19204
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 2.17615
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 2.17615
USH1G Usher syndrome 1G (autosomal recessive) 2.17615
GPR75 G protein-coupled receptor 75 2.17615
CLEC12A C-type lectin domain family 12, member A 2.17615
IL4I1 interleukin 4 induced 1 2.17615
STKLD1 serine/threonine kinase-like domain containing 1 2.17615
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 2.17615
NDRG1 N-myc downstream regulated 1 2.17615
ZACN zinc activated ligand-gated ion channel 2.17615
NAPSA napsin A aspartic peptidase 2.17615
MYO7A myosin VIIA 2.17615
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z 2.17615
LRRD1 leucine-rich repeats and death domain containing 1 2.17615
FAM180A family with sequence similarity 180, member A 2.17615
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 2.17615
TUBB8 tubulin, beta 8 class VIII 2.17615
RSPO3 R-spondin 3 2.17615
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 2.17615
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 2.17615
ZNF792 zinc finger protein 792 2.17615
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2 2.17615
PTGER3 prostaglandin E receptor 3 (subtype EP3) 2.17615
TDRKH tudor and KH domain containing 2.17615
TMEM217 transmembrane protein 217 2.17615
LCN10 lipocalin 10 2.17615
MOGAT3 monoacylglycerol O-acyltransferase 3 2.17615
HEXIM2 hexamethylene bis-acetamide inducible 2 2.17615
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7 2.17615
NPSR1 neuropeptide S receptor 1 2.17615
SPINK1 serine peptidase inhibitor, Kazal type 1 2.17615
PGAM2 phosphoglycerate mutase 2 (muscle) 2.17615
PGAM4 phosphoglycerate mutase family member 4 2.17615
SIRPB1 signal-regulatory protein beta 1 2.17615
SGPP2 sphingosine-1-phosphate phosphatase 2 2.17615
CCDC62 coiled-coil domain containing 62 2.17615
CCNO cyclin O 2.17615
GJB3 gap junction protein, beta 3, 31kDa 2.17615
LRRC52 leucine rich repeat containing 52 2.17615
AIFM3 apoptosis-inducing factor, mitochondrion-associated, 3 2.17615
PTH2 parathyroid hormone 2 2.17615
TTLL2 tubulin tyrosine ligase-like family member 2 2.17615
MSANTD7 Myb/SANT DNA binding domain containing 7 2.17615
ACTA2 actin, alpha 2, smooth muscle, aorta 2.17615
RHCE Rh blood group, CcEe antigens 2.17615
TCERG1L transcription elongation regulator 1-like 2.17615
SPRR2F small proline-rich protein 2F 2.17615
GIPR gastric inhibitory polypeptide receptor 2.17615
NEURL3 neuralized E3 ubiquitin protein ligase 3 2.17615
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 2.17615
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B 2.17615
MYL10 myosin, light chain 10, regulatory 2.17615
ZNF441 zinc finger protein 441 2.17615
LITAFD LITAF domain containing 2.17615
ZNF221 zinc finger protein 221 2.17615
MGAT4D MGAT4 family, member D 2.17615
LOC122526780 uncharacterized LOC122526780 2.17615
GREP1 glycine rich extracellular protein 1 2.17615
CPHXL cytoplasmic polyadenylated homeobox like 2.17615
DUSP29 dual specificity phosphatase 29 2.17615
CFAP157 cilia and flagella associated protein 157 2.17615
CCDC163 CCDC163 homolog 2.17615
ANGPTL8 angiopoietin like 8 2.17615
H3-5 H3.5 histone 2.17615
TMOD4 tropomodulin 4 (muscle) 2.17615
CD300LF CD300 molecule-like family member f 2.17615
MYH2 myosin, heavy chain 2, skeletal muscle, adult 2.17615
TBX10 T-box 10 2.17615
PRDM7 PR domain containing 7 2.17615
PTGDR2 prostaglandin D2 receptor 2 2.17615
LGALS7B lectin, galactoside-binding, soluble, 7B 2.17615
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 2.17615
CCDC17 coiled-coil domain containing 17 2.17615
CFAP99 cilia and flagella associated protein 99 2.17615
PTPRE protein tyrosine phosphatase, receptor type, E 2.17615
POMC proopiomelanocortin 2.17615
PCDHA6 protocadherin alpha 6 2.17615
ACTL10 actin-like 10 2.17615
ATP13A4 ATPase type 13A4 2.17615
ZNF597 zinc finger protein 597 2.17615
GOLGA7B golgin A7 family, member B 2.17615
GGACT gamma-glutamylamine cyclotransferase 2.17615
HNF1A HNF1 homeobox A 2.17615
SOAT2 sterol O-acyltransferase 2 2.17615
VCX3B variable charge, X-linked 3B 2.17615
GTSF1 gametocyte specific factor 1 2.17615
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 2.17615
TMEM179 transmembrane protein 179 2.17615
NPFF neuropeptide FF-amide peptide precursor 2.17615
FAM186A family with sequence similarity 186, member A 2.17615
APOBEC4 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative) 2.17615
SLC45A2 solute carrier family 45, member 2 2.17615
BHLHA9 basic helix-loop-helix family, member a9 2.17615
FPR2 formyl peptide receptor 2 2.17615
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 2.17615
TRIM29 tripartite motif containing 29 2.17615
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 2.17615
ASTN1 astrotactin 1 2.17615
GCOM1 GRINL1A complex locus 1 2.17615
ANKRD63 ankyrin repeat domain 63 2.17615
TIGD3 tigger transposable element derived 3 2.17615
LRRIQ3 leucine-rich repeats and IQ motif containing 3 2.17615
C2ORF66 chromosome 2 open reading frame 66 2.17615
MAP3K19 mitogen-activated protein kinase kinase kinase 19 2.17615
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 2.17615
C11ORF16 chromosome 11 open reading frame 16 2.17615
KLHL6 kelch-like family member 6 2.17615
GSTT2B glutathione S-transferase theta 2B (gene/pseudogene) 2.17615
CST6 cystatin E/M 2.17615
AGR3 anterior gradient 3 2.17615
AGR2 anterior gradient 2 2.17615
SCGB2A1 secretoglobin, family 2A, member 1 2.17615
HSPB2 heat shock 27kDa protein 2 2.17615
CHAC2 ChaC, cation transport regulator homolog 2 (E. coli) 2.17615
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 2.17615
CCDC157 coiled-coil domain containing 157 2.17615
ZNF132 zinc finger protein 132 2.17615
SMKR1 small lysine-rich protein 1 2.17615
CLDN34 claudin 34 2.17615
C22ORF42 chromosome 22 open reading frame 42 2.17615
MUC16 mucin 16, cell surface associated 2.17615
ZHX3 zinc fingers and homeoboxes 3 2.17615
PIP prolactin-induced protein 2.17615
PLA2G12A phospholipase A2, group XIIA 2.17615
TRIM7 tripartite motif containing 7 2.17615
C1ORF105 chromosome 1 open reading frame 105 2.17615
KCNA7 potassium channel, voltage gated shaker related subfamily A, member 7 2.17615
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 2.17615
CCDC70 coiled-coil domain containing 70 2.17615
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 2.17615
DRC1 dynein regulatory complex subunit 1 2.17615
BTG4 B-cell translocation gene 4 2.17615
TG thyroglobulin 2.17615
RIPPLY2 ripply transcriptional repressor 2 2.17615
C8G complement component 8, gamma polypeptide 2.17615
ISL2 ISL LIM homeobox 2 2.17615
LPAR1 lysophosphatidic acid receptor 1 2.17615
TEX19 testis expressed 19 2.17615
KLK14 kallikrein-related peptidase 14 2.17615
COL6A5 collagen, type VI, alpha 5 2.17615
NTF4 neurotrophin 4 2.17615
TEX12 testis expressed 12 2.17615
KLK6 kallikrein-related peptidase 6 2.17615
SAMD5 sterile alpha motif domain containing 5 2.17615
TBX2 T-box 2 2.17615
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 2.17615
COL15A1 collagen, type XV, alpha 1 2.17615
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 2.17615
LHX6 LIM homeobox 6 2.17615
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 2.17615
ENG endoglin 2.17615
CTAG2 cancer/testis antigen 2 2.17615
SPDEF SAM pointed domain containing ETS transcription factor 2.17615
KRTAP13-4 keratin associated protein 13-4 2.17615
R3HDML R3H domain containing-like 2.17615
MRGPRX3 MAS-related GPR, member X3 2.17615
C5ORF46 chromosome 5 open reading frame 46 2.17615
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 2.17615
INTS3 integrator complex subunit 3 2.17615
PTK6 protein tyrosine kinase 6 2.17615
OXT oxytocin/neurophysin I prepropeptide 2.17615
SBF2 SET binding factor 2 2.17615
PRDM13 PR domain containing 13 2.17615
BMP3 bone morphogenetic protein 3 2.17615
BMP5 bone morphogenetic protein 5 2.17615
GALR2 galanin receptor 2 2.17615
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 2.17615
HBEGF heparin-binding EGF-like growth factor 2.17615
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 2.17615
ASCL2 achaete-scute family bHLH transcription factor 2 2.17615
CEP72 centrosomal protein 72kDa 2.17615
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 2.17615
TRPM3 transient receptor potential cation channel, subfamily M, member 3 2.17615
FAM25G family with sequence similarity 25, member G 2.17615
PSORS1C2 psoriasis susceptibility 1 candidate 2 2.17615
FGF17 fibroblast growth factor 17 2.17615
FSTL3 follistatin-like 3 (secreted glycoprotein) 2.17615
CARNS1 carnosine synthase 1 2.17615
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase) 2.17615
JPH2 junctophilin 2 2.17615
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 2.17615
CD8A CD8a molecule 2.17615
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 2.17615
SAP25 Sin3A-associated protein, 25kDa 2.17615
AGBL4 ATP/GTP binding protein-like 4 2.17615
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa 2.17615
TMEM45B transmembrane protein 45B 2.17615
SYTL2 synaptotagmin-like 2 2.17615
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 2.17615
UPP2 uridine phosphorylase 2 2.17615
SERTM1 serine-rich and transmembrane domain containing 1 2.17384
FUBP3 far upstream element (FUSE) binding protein 3 2.16349
MLXIP MLX interacting protein 2.14271
RAB22A RAB22A, member RAS oncogene family 2.13936
TRAF5 TNF receptor-associated factor 5 2.12629
ZNF264 zinc finger protein 264 2.12448
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.10801
PRDM4 PR domain containing 4 2.07985
ZMYND11 zinc finger, MYND-type containing 11 2.07309
PIR pirin (iron-binding nuclear protein) 2.07309
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 2.07119
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 2.05735
KTN1 kinectin 1 (kinesin receptor) 2.03538
GPRC5C G protein-coupled receptor, class C, group 5, member C 2.0089
STX1A syntaxin 1A (brain) 2.00003

decreased expression

Symbol Name Standardized Value
BAIAP2L2 BAI1-associated protein 2-like 2 -2.26376
YARS1 tyrosyl-tRNA synthetase 1 -2.26376
ADCK5 aarF domain containing kinase 5 -2.26376
RPL34 ribosomal protein L34 -2.26376
POU2AF3 POU class 2 homeobox associating factor 3 -2.26376
SPTBN5 spectrin, beta, non-erythrocytic 5 -2.26376
DCDC1 doublecortin domain containing 1 -2.26376
ZHX1 zinc fingers and homeoboxes 1 -2.26376
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2 -2.26376
SCUBE3 signal peptide, CUB domain, EGF-like 3 -2.26376
ZNF793 zinc finger protein 793 -2.23634
CCR10 chemokine (C-C motif) receptor 10 -2.2203
SCML1 sex comb on midleg-like 1 (Drosophila) -2.2203
ANKRD44 ankyrin repeat domain 44 -2.20901
PARD3B par-3 family cell polarity regulator beta -2.20901
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) -2.17615
GRHL1 grainyhead-like 1 (Drosophila) -2.17615
METRNL meteorin, glial cell differentiation regulator-like -2.17615
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 -2.17615
TMPRSS11D transmembrane protease, serine 11D -2.17615
TNNT2 troponin T type 2 (cardiac) -2.17615
ASNS asparagine synthetase (glutamine-hydrolyzing) -2.17615
MYO1H myosin IH -2.17615
LNX2 ligand of numb-protein X 2 -2.17615
HSBP1L1 heat shock factor binding protein 1-like 1 -2.17615
GPR20 G protein-coupled receptor 20 -2.17615
SWI5 SWI5 recombination repair homolog (yeast) -2.17615
NNT nicotinamide nucleotide transhydrogenase -2.17615
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 -2.17615
GCSH glycine cleavage system protein H (aminomethyl carrier) -2.17615
GJA4 gap junction protein, alpha 4, 37kDa -2.17615
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) -2.17615
RHBDL2 rhomboid, veinlet-like 2 (Drosophila) -2.17615
ZNF442 zinc finger protein 442 -2.17615
CASZ1 castor zinc finger 1 -2.17615
ATP5PF ATP synthase peripheral stalk subunit F6 -2.17615
PNMA8B PNMA family member 8B -2.17615
CZIB CXXC motif containing zinc binding protein -2.17615
ZNG1A Zn regulated GTPase metalloprotein activator 1A -2.17615
MARCHF9 membrane associated ring-CH-type finger 9 -2.17615
DYNC2I2 dynein 2 intermediate chain 2 -2.17615
CIMAP3 ciliary microtubule associated protein 3 -2.17615
RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1 -2.17615
AP3B2 adaptor-related protein complex 3, beta 2 subunit -2.17615
THOC1 THO complex 1 -2.17615
LBHD1 LBH domain containing 1 -2.17615
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic -2.17615
DNAI2 dynein, axonemal, intermediate chain 2 -2.17615
IZUMO1 izumo sperm-egg fusion 1 -2.17615
GGT1 gamma-glutamyltransferase 1 -2.17615
TSGA10IP testis specific, 10 interacting protein -2.17615
ACTA1 actin, alpha 1, skeletal muscle -2.17615
RPL13 ribosomal protein L13 -2.17615
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38 -2.17615
CPAP centrosome assembly and centriole elongation protein -2.17615
CFAP57 cilia and flagella associated protein 57 -2.17615
GJC3 gap junction protein, gamma 3, 30.2kDa -2.17615
KDM8 lysine (K)-specific demethylase 8 -2.17615
SMIM24 small integral membrane protein 24 -2.17615
CLRN1 clarin 1 -2.17615
AP2A2 adaptor-related protein complex 2, alpha 2 subunit -2.17615
GABRD gamma-aminobutyric acid (GABA) A receptor, delta -2.17615
SPATA32 spermatogenesis associated 32 -2.17615
RORA RAR-related orphan receptor A -2.17615
IFI16 interferon, gamma-inducible protein 16 -2.17615
SEC11A SEC11 homolog A (S. cerevisiae) -2.17615
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 -2.17615
ANKFN1 ankyrin-repeat and fibronectin type III domain containing 1 -2.17615
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) -2.17615
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -2.17615
ADGRL4 adhesion G protein-coupled receptor L4 -2.17615
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like -2.17615
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 -2.17615
UBXN10 UBX domain protein 10 -2.17615
HSPD1 heat shock 60kDa protein 1 (chaperonin) -2.17615
TRHR thyrotropin-releasing hormone receptor -2.17615
KLK13 kallikrein-related peptidase 13 -2.17615
PCDH10 protocadherin 10 -2.17615
PCYT1A phosphate cytidylyltransferase 1, choline, alpha -2.17615
PUS1 pseudouridylate synthase 1 -2.17615
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast) -2.17615
FAM161B family with sequence similarity 161, member B -2.17615
RAMP3 receptor (G protein-coupled) activity modifying protein 3 -2.17615
PAIP2 poly(A) binding protein interacting protein 2 -2.17615
ANGPTL4 angiopoietin-like 4 -2.17615
SPAG6 sperm associated antigen 6 -2.17615
CIB1 calcium and integrin binding 1 (calmyrin) -2.17615
GOPC golgi-associated PDZ and coiled-coil motif containing -2.17615
CD8B CD8b molecule -2.17615
CCDC71L coiled-coil domain containing 71-like -2.17615
APCDD1 adenomatosis polyposis coli down-regulated 1 -2.17615
C9ORF72 chromosome 9 open reading frame 72 -2.17384
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa -2.16925
NUCB2 nucleobindin 2 -2.16031
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B -2.15605
SAMD14 sterile alpha motif domain containing 14 -2.15605
ICAM1 intercellular adhesion molecule 1 -2.15605
PLK3 polo-like kinase 3 -2.15605
TRIL TLR4 interactor with leucine-rich repeats -2.15605
GSTM2 glutathione S-transferase mu 2 (muscle) -2.15605
ANO8 anoctamin 8 -2.15076
SPIN4 spindlin family, member 4 -2.14271
PEBP1 phosphatidylethanolamine binding protein 1 -2.14271
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 -2.12046
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) -2.11724
SH3BP5 SH3-domain binding protein 5 (BTK-associated) -2.07973
CCDC169 coiled-coil domain containing 169 -2.07973
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -2.0753
ZBTB41 zinc finger and BTB domain containing 41 -2.07309
PPID peptidylprolyl isomerase D -2.05584
UTP4 UTP4 small subunit processome component -2.04549
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa -2.04357
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 -2.04357
LRRC1 leucine rich repeat containing 1 -2.03919
DPF1 D4, zinc and double PHD fingers family 1 -2.03919
SRSF3 serine/arginine-rich splicing factor 3 -2.03684
LDAF1 lipid droplet assembly factor 1 -2.03538
ALG9 ALG9, alpha-1,2-mannosyltransferase -2.02296
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 -2.01918
NCKAP5L NCK-associated protein 5-like -2.01918
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 -2.00886
MZF1 myeloid zinc finger 1 -2.00003
KLHL4 kelch-like family member 4 -2.00003