PD0332991 Gene Set

Dataset LINCS KinomeScan Kinase Inhibitor Targets
Category physical interactions
Type small molecule
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Genes

45 kinases inhibited by the PD0332991 small molecule from the KinomeScan Kinase Inhibitor Targets dataset.

Symbol Name Standardized Value
CSNK2A1 casein kinase 2, alpha 1 polypeptide 1.36211
HIPK1 homeodomain interacting protein kinase 1 1.36211
CDK16 cyclin-dependent kinase 16 1.35325
HIPK2 homeodomain interacting protein kinase 2 1.34449
CLK2 CDC-like kinase 2 1.33582
DAPK3 death-associated protein kinase 3 1.32726
CSNK2A2 casein kinase 2, alpha prime polypeptide 1.3104
MAPK7 mitogen-activated protein kinase 7 1.3104
IRAK1 interleukin-1 receptor-associated kinase 1 1.29393
NUAK2 NUAK family, SNF1-like kinase, 2 1.28583
CDKL5 cyclin-dependent kinase-like 5 1.28583
CLK1 CDC-like kinase 1 1.26991
SLK STE20-like kinase 1.26209
CLK4 CDC-like kinase 4 1.20983
HIPK3 homeodomain interacting protein kinase 3 1.20271
DAPK1 death-associated protein kinase 1 1.18186
DAPK2 death-associated protein kinase 2 1.18186
CDK17 cyclin-dependent kinase 17 1.16177
DCLK2 doublecortin-like kinase 2 1.14877
DCLK1 doublecortin-like kinase 1 1.14877
ULK1 unc-51 like autophagy activating kinase 1 1.1361
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B 1.12988
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.12988
CIT citron rho-interacting serine/threonine kinase 1.12988
STK16 serine/threonine kinase 16 1.11767
MAP3K3 mitogen-activated protein kinase kinase kinase 3 1.0718
CAMK2B calcium/calmodulin-dependent protein kinase II beta 1.06105
GAK cyclin G associated kinase 1.06105
MAST1 microtubule associated serine/threonine kinase 1 1.03041
CDK14 cyclin-dependent kinase 14 1.03041
PHKG2 phosphorylase kinase, gamma 2 (testis) 1.03041
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 1.00664
HIPK4 homeodomain interacting protein kinase 4 0.984392
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.963557
CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase) 0.9517
STK39 serine threonine kinase 39 0.9517
CAMK1D calcium/calmodulin-dependent protein kinase ID 0.93295
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.93295
MINK1 misshapen-like kinase 1 0.922275
TSSK1B testis-specific serine kinase 1B 0.908676
MARK3 MAP/microtubule affinity-regulating kinase 3 0.908676
TAOK3 TAO kinase 3 0.905385
PLK1 polo-like kinase 1 0.895762
MAPK15 mitogen-activated protein kinase 15 0.866209
DCLK3 doublecortin-like kinase 3 0.860727