PDCD1 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description programmed cell death 1|This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5133)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PDCD1
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Genes

73 co-expressed genes for PDCD1 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ADAM20 ADAM metallopeptidase domain 20
ADAMTSL3 ADAMTS-like 3
AOC4P amine oxidase, copper containing 4, pseudogene
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATXN3 ataxin 3
BRD4 bromodomain containing 4
CADM4 cell adhesion molecule 4
CALN1 calneuron 1
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCL16 chemokine (C-C motif) ligand 16
CD8A CD8a molecule
CDC73 cell division cycle 73
COL19A1 collagen, type XIX, alpha 1
COL8A1 collagen, type VIII, alpha 1
EDIL3 EGF-like repeats and discoidin I-like domains 3
ERCC4 excision repair cross-complementation group 4
EXOC4 exocyst complex component 4
F2RL3 coagulation factor II (thrombin) receptor-like 3
FAM153B family with sequence similarity 153, member B
FBXL4 F-box and leucine-rich repeat protein 4
FSHR follicle stimulating hormone receptor
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
FZD5 frizzled class receptor 5
GCA grancalcin, EF-hand calcium binding protein
GPR171 G protein-coupled receptor 171
GUCY2F guanylate cyclase 2F, retinal
HCG8 HLA complex group 8
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFNA10 interferon, alpha 10
IL4 interleukin 4
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
JRKL JRK-like
KRT2 keratin 2, type II
KRT34 keratin 34, type I
LECT2 leukocyte cell-derived chemotaxin 2
LGI1 leucine-rich, glioma inactivated 1
LOR loricrin
MAGEA9 melanoma antigen family A9
NEB nebulin
NHEJ1 nonhomologous end-joining factor 1
NPFF neuropeptide FF-amide peptide precursor
NR3C2 nuclear receptor subfamily 3, group C, member 2
NTNG2 netrin G2
OCM oncomodulin
OR10H3 olfactory receptor, family 10, subfamily H, member 3
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PAX6 paired box 6
PCDHGB7 protocadherin gamma subfamily B, 7
PDCD1 programmed cell death 1
PGM3 phosphoglucomutase 3
PHOX2B paired-like homeobox 2b
PSG1 pregnancy specific beta-1-glycoprotein 1
PVR poliovirus receptor
RAD51D RAD51 paralog D
RREB1 ras responsive element binding protein 1
RXRG retinoid X receptor, gamma
S100A5 S100 calcium binding protein A5
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
SGPL1 sphingosine-1-phosphate lyase 1
SIX6 SIX homeobox 6
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SPA17 sperm autoantigenic protein 17
STAC SH3 and cysteine rich domain
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TBX19 T-box 19
TMEM26 transmembrane protein 26
TSSK2 testis-specific serine kinase 2
ZBTB14 zinc finger and BTB domain containing 14
ZSCAN26 zinc finger and SCAN domain containing 26