PDCD2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description programmed cell death 2|This gene encodes a nuclear protein expressed in a variety of tissues. Expression of this gene has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on this protein. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 9 and 12. [provided by RefSeq, Dec 2010] (NCBI Entrez Gene Database, 5134)
External Link http://www.ncbi.nlm.nih.gov/gene/5134
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Genes

116 interacting proteins for PDCD2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACAD11 acyl-CoA dehydrogenase family, member 11
ACSL3 acyl-CoA synthetase long-chain family member 3
AGO1 argonaute RISC catalytic component 1
AGO2 argonaute RISC catalytic component 2
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ANKMY2 ankyrin repeat and MYND domain containing 2
ANKRD28 ankyrin repeat domain 28
ANKRD44 ankyrin repeat domain 44
ANKRD52 ankyrin repeat domain 52
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
AURKB aurora kinase B
C14ORF80 chromosome 14 open reading frame 80
CACYBP calcyclin binding protein
CD3EAP CD3e molecule, epsilon associated protein
CDC37 cell division cycle 37
CDC37L1 cell division cycle 37-like 1
CDK11A cyclin-dependent kinase 11A
CDK4 cyclin-dependent kinase 4
CDK9 cyclin-dependent kinase 9
CETN1 centrin, EF-hand protein, 1
CETN2 centrin, EF-hand protein, 2
CETN3 centrin, EF-hand protein, 3
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHUK conserved helix-loop-helix ubiquitous kinase
COPA coatomer protein complex, subunit alpha
CUL1 cullin 1
CXORF57 chromosome X open reading frame 57
DICER1 dicer 1, ribonuclease type III
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
EGLN1 egl-9 family hypoxia-inducible factor 1
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FBXW11 F-box and WD repeat domain containing 11
FKBP5 FK506 binding protein 5
FN3KRP fructosamine 3 kinase related protein
GLMN glomulin, FKBP associated protein
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HCFC1 host cell factor C1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
ILK integrin-linked kinase
ILVBL ilvB (bacterial acetolactate synthase)-like
IPO7 importin 7
IPO9 importin 9
IQGAP2 IQ motif containing GTPase activating protein 2
KIF1BP KIF1 binding protein
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)
LRPPRC leucine-rich pentatricopeptide repeat containing
LRRC40 leucine rich repeat containing 40
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3
MCC mutated in colorectal cancers
MCM4 minichromosome maintenance complex component 4
MCM6 minichromosome maintenance complex component 6
MCMBP minichromosome maintenance complex binding protein
MTIF2 mitochondrial translational initiation factor 2
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit
NCOR1 nuclear receptor corepressor 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NUDC nudC nuclear distribution protein
NUDCD3 NudC domain containing 3
NUP85 nucleoporin 85kDa
PARK2 parkin RBR E3 ubiquitin protein ligase
PNPLA2 patatin-like phospholipase domain containing 2
POLR1A polymerase (RNA) I polypeptide A, 194kDa
POLR1B polymerase (RNA) I polypeptide B, 128kDa
POLR1D polymerase (RNA) I polypeptide D, 16kDa
POLR1E polymerase (RNA) I polypeptide E, 53kDa
POLR2H polymerase (RNA) II (DNA directed) polypeptide H
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP5C protein phosphatase 5, catalytic subunit
PPP6C protein phosphatase 6, catalytic subunit
PPP6R1 protein phosphatase 6, regulatory subunit 1
PPP6R2 protein phosphatase 6, regulatory subunit 2
PPP6R3 protein phosphatase 6, regulatory subunit 3
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PTGES3 prostaglandin E synthase 3 (cytosolic)
PYGL phosphorylase, glycogen, liver
RASAL2 RAS protein activator like 2
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RPN1 ribophorin I
SGPL1 sphingosine-1-phosphate lyase 1
SHCBP1 SHC SH2-domain binding protein 1
SHPRH SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
SKP1 S-phase kinase-associated protein 1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SRPR signal recognition particle receptor (docking protein)
SRPRB signal recognition particle receptor, B subunit
STIP1 stress-induced phosphoprotein 1
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
TTC4 tetratricopeptide repeat domain 4
TUBA1A tubulin, alpha 1a
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBC ubiquitin C
UBR5 ubiquitin protein ligase E3 component n-recognin 5
USP43 ubiquitin specific peptidase 43
USP44 ubiquitin specific peptidase 44
USP49 ubiquitin specific peptidase 49
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae)
WDR3 WD repeat domain 3
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta