PDGFRA Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description platelet-derived growth factor receptor, alpha polypeptide|This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012] (NCBI Entrez Gene Database, 5156)
External Link https://ncbi.nlm.nih.gov/gene/5156
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Genes

499 genes differentially expressed following the PDGFRA gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
LTF lactotransferrin 0.0178784
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.0171268
AK4 adenylate kinase 4 0.0145707
TXNDC9 thioredoxin domain containing 9 0.0142979
F13A1 coagulation factor XIII, A1 polypeptide 0.0132967
HNMT histamine N-methyltransferase 0.0130052
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.012736
TMEM14B transmembrane protein 14B 0.0120439
NRGN neurogranin (protein kinase C substrate, RC3) 0.0114455
TUBB2A tubulin, beta 2A class IIa 0.0114203
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.0111731
CDCA4 cell division cycle associated 4 0.0111657
ECI2 enoyl-CoA delta isomerase 2 0.0108207
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.0107284
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.0106866
RGS10 regulator of G-protein signaling 10 0.0106309
CPVL carboxypeptidase, vitellogenic-like 0.0105906
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.010551
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.0104784
ATP5MJ ATP synthase membrane subunit j 0.0104265
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.0103672
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.0102803
NUSAP1 nucleolar and spindle associated protein 1 0.0102239
FKBP1B FK506 binding protein 1B, 12.6 kDa 0.0102168
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.0101159
HIST3H2A histone cluster 3, H2a 0.0100569
NSL1 NSL1, MIS12 kinetochore complex component 0.0100405
CRYM crystallin, mu 0.00995807
COL4A5 collagen, type IV, alpha 5 0.00995148
NDN necdin, melanoma antigen (MAGE) family member 0.00991479
C1ORF54 chromosome 1 open reading frame 54 0.00987137
NME5 NME/NM23 family member 5 0.00986119
PEG3 paternally expressed 3 0.00984244
APOC2 apolipoprotein C-II 0.00979149
PRKCB protein kinase C, beta 0.00970199
RNASE6 ribonuclease, RNase A family, k6 0.00969598
SEPP1 selenoprotein P, plasma, 1 0.00967239
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.00965037
GPX1 glutathione peroxidase 1 0.00961736
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.009544
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.00942014
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein 0.00928956
TSPAN6 tetraspanin 6 0.00928878
MCUB mitochondrial calcium uniporter dominant negative subunit beta 0.00926857
ACP3 acid phosphatase 3 0.00923051
ASRGL1 asparaginase like 1 0.00915415
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 0.00914869
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.00914045
CHKB choline kinase beta 0.00911597
GPR183 G protein-coupled receptor 183 0.00907516
LRRC17 leucine rich repeat containing 17 0.00907083
VCAN versican 0.00906277
GCA grancalcin, EF-hand calcium binding protein 0.00901047
LY96 lymphocyte antigen 96 0.00900631
CRYL1 crystallin, lambda 1 0.00898959
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 0.00896432
NIPSNAP2 nipsnap homolog 2 0.00895884
DCXR dicarbonyl/L-xylulose reductase 0.00893553
GOLM1 golgi membrane protein 1 0.00892332
DIRAS3 DIRAS family, GTP-binding RAS-like 3 0.00889465
BPHL biphenyl hydrolase-like (serine hydrolase) 0.00884266
GADD45G growth arrest and DNA-damage-inducible, gamma 0.00882916
ATXN1 ataxin 1 0.0088063
SLC44A4 solute carrier family 44, member 4 0.00880057
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.00879624
GSTO1 glutathione S-transferase omega 1 0.00876883
ARL3 ADP-ribosylation factor-like 3 0.00875286
LST1 leukocyte specific transcript 1 0.00874294
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.0087214
MGST3 microsomal glutathione S-transferase 3 0.00863056
GTPBP8 GTP-binding protein 8 (putative) 0.00861603
CHP1 calcineurin-like EF-hand protein 1 0.00858212
CLDN10 claudin 10 0.00857869
DYNLT1 dynein, light chain, Tctex-type 1 0.00857746
FUCA1 fucosidase, alpha-L- 1, tissue 0.0085699
LYN LYN proto-oncogene, Src family tyrosine kinase 0.00855887
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.00855405
MSMB microseminoprotein, beta- 0.00849619
SPTSSA serine palmitoyltransferase, small subunit A 0.0084678
IFT52 intraflagellar transport 52 0.00845344
NDP Norrie disease (pseudoglioma) 0.00845056
DEFB1 defensin, beta 1 0.00839995
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.00838446
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.00835148
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 0.0083387
GREB1 growth regulation by estrogen in breast cancer 1 0.00833436
GLIPR1 GLI pathogenesis-related 1 0.00831881
RPS5 ribosomal protein S5 0.00831553
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.00830588
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.0082369
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 0.00823142
ETNK1 ethanolamine kinase 1 0.00818531
LYRM4 LYR motif containing 4 0.00816751
SESN1 sestrin 1 0.0081501
ZNF226 zinc finger protein 226 0.00814038
PDCD10 programmed cell death 10 0.00813209
PFDN5 prefoldin subunit 5 0.00813017
HOPX HOP homeobox 0.00811484
ERGIC3 ERGIC and golgi 3 0.00810315
HAL histidine ammonia-lyase 0.00809918
FMO5 flavin containing monooxygenase 5 0.00806019
NPC2 Niemann-Pick disease, type C2 0.0080487
GNG10 guanine nucleotide binding protein (G protein), gamma 10 0.00804306
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.00803801
CETN2 centrin, EF-hand protein, 2 0.00801562
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.00793502
NUP37 nucleoporin 37kDa 0.00791684
NMU neuromedin U 0.00788645
SAR1B secretion associated, Ras related GTPase 1B 0.00787169
CTSS cathepsin S 0.00784821
CPD carboxypeptidase D 0.00784218
TCEAL1 transcription elongation factor A (SII)-like 1 0.00784058
CCL5 chemokine (C-C motif) ligand 5 0.00783179
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 0.00779594
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.00779545
MTMR11 myotubularin related protein 11 0.00779004
UGP2 UDP-glucose pyrophosphorylase 2 0.0077865
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.00778242
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.00776619
ARID4A AT rich interactive domain 4A (RBP1-like) 0.0077598
SLA Src-like-adaptor 0.00775341
TMEM38B transmembrane protein 38B 0.00774401
LYZ lysozyme 0.00772935
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.00772844
C1ORF115 chromosome 1 open reading frame 115 0.00772625
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 0.00771201
THYN1 thymocyte nuclear protein 1 0.00770828
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.00769491
EFHC2 EF-hand domain (C-terminal) containing 2 0.00768478
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 0.00764278
TMEM45A transmembrane protein 45A 0.00763529
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00762578
SKP1 S-phase kinase-associated protein 1 0.00761538
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.00760519
LY86 lymphocyte antigen 86 0.00760042
CTSH cathepsin H 0.00756247
SHTN1 shootin 1 0.00755474
CCK cholecystokinin 0.00753265
STX8 syntaxin 8 0.00752061
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 0.007504
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.00748893
COMMD8 COMM domain containing 8 0.0074488
ORC5 origin recognition complex, subunit 5 0.00741643
CD2 CD2 molecule 0.00741527
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.00738837
MED7 mediator complex subunit 7 0.00737803
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.00737256
CENPU centromere protein U 0.00736133
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 0.00734137
WASHC4 WASH complex subunit 4 0.0073368
RESF1 retroelement silencing factor 1 0.00732268
TREM1 triggering receptor expressed on myeloid cells 1 0.00732123
LGALS1 lectin, galactoside-binding, soluble, 1 0.0073055
STOM stomatin 0.00728685
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.00728547
SDHAF3 succinate dehydrogenase complex assembly factor 3 0.0072829
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 0.00726965
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.00726813
DAZAP2 DAZ associated protein 2 0.0072478
ALAD aminolevulinate dehydratase 0.00723462
HSPB11 heat shock protein family B (small), member 11 0.00721854
MLF1 myeloid leukemia factor 1 0.00721078
ARL5A ADP-ribosylation factor-like 5A 0.00721063
WDR61 WD repeat domain 61 0.00720064
TSPAN31 tetraspanin 31 0.00719419
CCL20 chemokine (C-C motif) ligand 20 0.00719117
TM7SF2 transmembrane 7 superfamily member 2 0.00715313
FRG1 FSHD region gene 1 0.00712125
CD48 CD48 molecule 0.00710619
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.00709354
HOXB2 homeobox B2 0.00708982
BIK BCL2-interacting killer (apoptosis-inducing) 0.00708976
SETMAR SET domain and mariner transposase fusion gene 0.00707677
JCHAIN joining chain of multimeric IgA and IgM 0.00707321
ADAM9 ADAM metallopeptidase domain 9 0.00707198
GOLGA7 golgin A7 0.00706802
CPQ carboxypeptidase Q 0.00706754
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic 0.00705933
IQCG IQ motif containing G 0.00702446
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 0.00700769
OXSM 3-oxoacyl-ACP synthase, mitochondrial 0.00699534
TMX1 thioredoxin-related transmembrane protein 1 0.0069915
TMEM168 transmembrane protein 168 0.00699065
TSNAX translin-associated factor X 0.00697951
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.00697628
KRAS Kirsten rat sarcoma viral oncogene homolog 0.00694853
CST3 cystatin C 0.00693696
MDFIC MyoD family inhibitor domain containing 0.00693214
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.00692209
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.00691274
MRPS28 mitochondrial ribosomal protein S28 0.00691017
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.00690515
PEX11B peroxisomal biogenesis factor 11 beta 0.00690254
COPS4 COP9 signalosome subunit 4 0.00690048
AIF1 allograft inflammatory factor 1 0.00688457
VRK1 vaccinia related kinase 1 0.00688065
GTF2H5 general transcription factor IIH, polypeptide 5 0.00686992
GLUD1 glutamate dehydrogenase 1 0.00686694
RAB20 RAB20, member RAS oncogene family 0.00684619
WDR47 WD repeat domain 47 0.00683993
SYK spleen tyrosine kinase 0.00683643
TMEM165 transmembrane protein 165 0.00683362
LTA4H leukotriene A4 hydrolase 0.00682985
GOLT1B golgi transport 1B 0.00682895
RHOT1 ras homolog family member T1 0.00680962
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) 0.00679495
NIBAN1 niban apoptosis regulator 1 0.00678755
AGA aspartylglucosaminidase 0.00678503
PON2 paraoxonase 2 0.00678446
MSMO1 methylsterol monooxygenase 1 0.0067832
TOX3 TOX high mobility group box family member 3 0.0067821
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00678136
BAG2 BCL2-associated athanogene 2 0.00676908
GLRX5 glutaredoxin 5 0.00676183
CRIP1 cysteine-rich protein 1 (intestinal) 0.00675821
ZNF277 zinc finger protein 277 0.00675552
MIPEP mitochondrial intermediate peptidase 0.00675267
ERGIC2 ERGIC and golgi 2 0.00674525
ZBTB18 zinc finger and BTB domain containing 18 0.00672383
CNIH1 cornichon family AMPA receptor auxiliary protein 1 0.00672237
POLR2G polymerase (RNA) II (DNA directed) polypeptide G 0.00671106
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.00670992
CCNG1 cyclin G1 0.00670426
AKAP7 A kinase (PRKA) anchor protein 7 0.00670352
PLTP phospholipid transfer protein 0.00669856
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.00669583
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 0.00668842
METTL7A methyltransferase like 7A 0.00665534
LTBP1 latent transforming growth factor beta binding protein 1 0.00664204
GZMK granzyme K (granzyme 3; tryptase II) 0.00663929
RAB38 RAB38, member RAS oncogene family 0.00663705
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.00663638
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.00663372
OLFM4 olfactomedin 4 0.00662951
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 0.00662627
HOXA5 homeobox A5 0.0066252
CAPG capping protein (actin filament), gelsolin-like 0.00659939
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 0.00659653
HPF1 histone PARylation factor 1 0.00659001
SIVA1 SIVA1, apoptosis-inducing factor 0.00658788
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.00658282
UROD uroporphyrinogen decarboxylase 0.00657945
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 0.00657695
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 0.00657043
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 0.00656986
MAGT1 magnesium transporter 1 0.00656586
WFDC2 WAP four-disulfide core domain 2 0.00655891
SFRP1 secreted frizzled-related protein 1 0.00653344
EAPP E2F-associated phosphoprotein 0.00652487
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.0065046

decreased expression

Symbol Name Standardized Value
FABP4 fatty acid binding protein 4, adipocyte -0.0172398
CCNA2 cyclin A2 -0.0172255
HSPA1A heat shock 70kDa protein 1A -0.0168195
KRT14 keratin 14, type I -0.0159406
TIMP3 TIMP metallopeptidase inhibitor 3 -0.0153622
CCN2 cellular communication network factor 2 -0.0151893
SLC38A1 solute carrier family 38, member 1 -0.0141898
DYNLL1 dynein, light chain, LC8-type 1 -0.014049
AMOTL2 angiomotin like 2 -0.0138206
MET MET proto-oncogene, receptor tyrosine kinase -0.0138121
PEG10 paternally expressed 10 -0.0135915
TNNC1 troponin C type 1 (slow) -0.0134307
EPHA2 EPH receptor A2 -0.0132584
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.0130895
AUTS2 autism susceptibility candidate 2 -0.0128774
MAP7 microtubule-associated protein 7 -0.0128641
CRYAB crystallin, alpha B -0.0127106
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.0127092
SPRY2 sprouty homolog 2 (Drosophila) -0.0126481
MX1 MX dynamin-like GTPase 1 -0.0120157
STK10 serine/threonine kinase 10 -0.0116043
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.0115891
TAGLN transgelin -0.011467
GNAS GNAS complex locus -0.0114479
BMP2 bone morphogenetic protein 2 -0.0113949
IFI27 interferon, alpha-inducible protein 27 -0.0113295
MID1 midline 1 -0.0112609
LAMB1 laminin, beta 1 -0.0112373
G0S2 G0/G1 switch 2 -0.0112164
L1CAM L1 cell adhesion molecule -0.0111518
CXCL14 chemokine (C-X-C motif) ligand 14 -0.0111479
ADGRF5 adhesion G protein-coupled receptor F5 -0.0111134
NAV2 neuron navigator 2 -0.0110598
TFPI2 tissue factor pathway inhibitor 2 -0.0110202
AQP3 aquaporin 3 (Gill blood group) -0.0109889
MGLL monoglyceride lipase -0.0108674
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.0107489
DOCK9 dedicator of cytokinesis 9 -0.0107338
P3H2 prolyl 3-hydroxylase 2 -0.0107202
HSPB8 heat shock 22kDa protein 8 -0.0106064
MAGEA3 melanoma antigen family A3 -0.0105819
ITPRID2 ITPR interacting domain containing 2 -0.010498
KLF6 Kruppel-like factor 6 -0.0104731
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.0104716
LY6E lymphocyte antigen 6 complex, locus E -0.0102362
EXT1 exostosin glycosyltransferase 1 -0.0102357
ATF3 activating transcription factor 3 -0.0102037
MMP1 matrix metallopeptidase 1 -0.0101607
HMOX1 heme oxygenase 1 -0.0101407
PNN pinin, desmosome associated protein -0.00991548
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked -0.00978074
AEBP1 AE binding protein 1 -0.0097771
HSPA9 heat shock 70kDa protein 9 (mortalin) -0.00972295
SIK1 salt-inducible kinase 1 -0.00970211
CTSD cathepsin D -0.00969676
MCM2 minichromosome maintenance complex component 2 -0.00967334
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00964031
OLFML2A olfactomedin-like 2A -0.00961894
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon -0.00961106
CSRP2 cysteine and glycine-rich protein 2 -0.00956529
NOTCH1 notch 1 -0.00953778
HBEGF heparin-binding EGF-like growth factor -0.00951055
BGN biglycan -0.00947851
CLIC5 chloride intracellular channel 5 -0.0094779
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -0.00947326
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 -0.0094725
TRIM29 tripartite motif containing 29 -0.00946697
HK2 hexokinase 2 -0.00935871
SYNM synemin, intermediate filament protein -0.00935509
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.00934758
PODXL podocalyxin-like -0.00932762
ACTC1 actin, alpha, cardiac muscle 1 -0.00932483
LAMB3 laminin, beta 3 -0.00930625
EHD3 EH-domain containing 3 -0.00930263
RHOBTB3 Rho-related BTB domain containing 3 -0.00928365
LARP1 La ribonucleoprotein domain family, member 1 -0.00928308
RND3 Rho family GTPase 3 -0.00921655
CD40 CD40 molecule, TNF receptor superfamily member 5 -0.0091758
FCN3 ficolin (collagen/fibrinogen domain containing) 3 -0.00915868
SPRY4 sprouty homolog 4 (Drosophila) -0.00913155
HNRNPM heterogeneous nuclear ribonucleoprotein M -0.00907539
ASS1 argininosuccinate synthase 1 -0.00906443
NDNF neuron-derived neurotrophic factor -0.0090488
IRAK1 interleukin-1 receptor-associated kinase 1 -0.00903871
PXDN peroxidasin -0.00901006
ITGA6 integrin, alpha 6 -0.00896846
ADIRF adipogenesis regulatory factor -0.00892387
NRCAM neuronal cell adhesion molecule -0.0088962
RGS16 regulator of G-protein signaling 16 -0.00887901
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00884444
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.00882029
SRRM2 serine/arginine repetitive matrix 2 -0.00880628
PLXND1 plexin D1 -0.00876167
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00870074
SQSTM1 sequestosome 1 -0.00868242
KRT7 keratin 7, type II -0.00865849
TENT4A terminal nucleotidyltransferase 4A -0.00864839
LIPG lipase, endothelial -0.0085985
BTBD3 BTB (POZ) domain containing 3 -0.00856113
MYO1B myosin IB -0.00854342
JMJD6 jumonji domain containing 6 -0.00853718
ZBTB20 zinc finger and BTB domain containing 20 -0.00852299
MYC v-myc avian myelocytomatosis viral oncogene homolog -0.00847242
NUCLEOLIN nucleolin multifunctional protein -0.00845264
PRKD2 protein kinase D2 -0.00844599
IRS1 insulin receptor substrate 1 -0.00843586
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -0.00840738
HIST1H2BD histone cluster 1, H2bd -0.00838774
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.00838209
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.00836398
CCND3 cyclin D3 -0.00832926
FLRT3 fibronectin leucine rich transmembrane protein 3 -0.00831746
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -0.00831661
SLCO3A1 solute carrier organic anion transporter family, member 3A1 -0.00830765
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.0082928
EGR1 early growth response 1 -0.00828123
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.00827663
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.00827469
PARP12 poly (ADP-ribose) polymerase family, member 12 -0.00826737
DGKD diacylglycerol kinase, delta 130kDa -0.00824632
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.00824315
CDV3 CDV3 homolog (mouse) -0.00821322
RET ret proto-oncogene -0.00817965
NDRG1 N-myc downstream regulated 1 -0.00817008
NOLC1 nucleolar and coiled-body phosphoprotein 1 -0.0081315
CADM1 cell adhesion molecule 1 -0.00812742
KANK1 KN motif and ankyrin repeat domains 1 -0.00811894
ECM1 extracellular matrix protein 1 -0.00811383
VEGFA vascular endothelial growth factor A -0.00809505
APOLD1 apolipoprotein L domain containing 1 -0.00806498
IFRD1 interferon-related developmental regulator 1 -0.00804825
PLXNB2 plexin B2 -0.00803913
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -0.00803667
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -0.00802853
IGF1R insulin-like growth factor 1 receptor -0.00801141
NBPF10 neuroblastoma breakpoint family, member 10 -0.00800207
PLXNA1 plexin A1 -0.00799245
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00798636
SEC14L1 SEC14-like 1 (S. cerevisiae) -0.00798593
BAZ2A bromodomain adjacent to zinc finger domain, 2A -0.00798556
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) -0.00798081
MEST mesoderm specific transcript -0.00795764
ALAS1 5'-aminolevulinate synthase 1 -0.0079507
MAGEA12 melanoma antigen family A12 -0.00794169
OSBPL10 oxysterol binding protein-like 10 -0.00794088
ACKR3 atypical chemokine receptor 3 -0.00793802
RAB8A RAB8A, member RAS oncogene family -0.00791339
PDZD2 PDZ domain containing 2 -0.00790616
TUBB2B tubulin, beta 2B class IIb -0.00786848
MFSD10 major facilitator superfamily domain containing 10 -0.00786819
LIMCH1 LIM and calponin homology domains 1 -0.00784382
TENM3 teneurin transmembrane protein 3 -0.00784172
TENT5A terminal nucleotidyltransferase 5A -0.00781436
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) -0.00781355
DCHS1 dachsous cadherin-related 1 -0.00778559
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.00777145
AKR1C2 aldo-keto reductase family 1, member C2 -0.0077357
CST1 cystatin SN -0.00773446
VWF von Willebrand factor -0.00772933
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00771863
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.00769667
MMP3 matrix metallopeptidase 3 -0.00769306
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.00766711
NPIPB3 nuclear pore complex interacting protein family, member B3 -0.00765456
STC2 stanniocalcin 2 -0.00765387
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -0.00763949
CKM creatine kinase, muscle -0.00762295
KRT17 keratin 17, type I -0.00761984
NOP56 NOP56 ribonucleoprotein -0.00760927
RBM34 RNA binding motif protein 34 -0.00759955
ANXA3 annexin A3 -0.0075986
CHGB chromogranin B -0.00759399
NR4A2 nuclear receptor subfamily 4, group A, member 2 -0.00757101
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -0.00755042
LAMA5 laminin, alpha 5 -0.00754916
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) -0.00753993
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.00753636
GATAD2A GATA zinc finger domain containing 2A -0.00753444
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 -0.0075072
MACF1 microtubule-actin crosslinking factor 1 -0.00750106
KLF5 Kruppel-like factor 5 (intestinal) -0.00746408
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) -0.00744221
RASIP1 Ras interacting protein 1 -0.00744155
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -0.0074353
TTN titin -0.0074272
NR4A1 nuclear receptor subfamily 4, group A, member 1 -0.00742273
IFI44L interferon-induced protein 44-like -0.00739939
DKFZP586I1420 uncharacterized protein DKFZp586I1420 -0.0073891
EPS8L2 EPS8-like 2 -0.00737986
GPX3 glutathione peroxidase 3 -0.00737322
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -0.00736802
MAGEA1 melanoma antigen family A1 -0.00733386
JUP junction plakoglobin -0.00729951
CXCL2 chemokine (C-X-C motif) ligand 2 -0.00729524
CTSL cathepsin L -0.00727361
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 -0.00726674
SLIT2 slit homolog 2 (Drosophila) -0.00725335
IL6 interleukin 6 -0.00723509
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.00722197
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.00722003
NXN nucleoredoxin -0.00721484
AKAP8 A kinase (PRKA) anchor protein 8 -0.00719967
KPNB1 karyopherin (importin) beta 1 -0.00719702
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 -0.00719642
PELI1 pellino E3 ubiquitin protein ligase 1 -0.00719015
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 -0.00718747
SGCE sarcoglycan, epsilon -0.00713023
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.0071233
LAMA3 laminin, alpha 3 -0.007116
ZMYND8 zinc finger, MYND-type containing 8 -0.00711493
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 -0.00710409
ISG15 ISG15 ubiquitin-like modifier -0.00707881
DLX2 distal-less homeobox 2 -0.00704884
ATF4 activating transcription factor 4 -0.00704584
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 -0.00704333
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00704091
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) -0.00704009
FLT1 fms-related tyrosine kinase 1 -0.00702944
NEBL nebulette -0.00702682
NOTCH2NL notch 2 N-terminal like -0.00702485
BCAP31 B-cell receptor-associated protein 31 -0.00702442
CRABP2 cellular retinoic acid binding protein 2 -0.00699012
TM4SF1 transmembrane 4 L six family member 1 -0.00697193
CDK11A cyclin-dependent kinase 11A -0.00695907
SDHAP1 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1 -0.0069535
KRT16 keratin 16, type I -0.00694699
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.00693585
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) -0.00693523
CTNND1 catenin (cadherin-associated protein), delta 1 -0.00692733
RRBP1 ribosome binding protein 1 -0.00691641
ACTA1 actin, alpha 1, skeletal muscle -0.00691626
MTCL1 microtubule crosslinking factor 1 -0.00691121
SWAP70 SWAP switching B-cell complex 70kDa subunit -0.00691119
PIEZO1 piezo-type mechanosensitive ion channel component 1 -0.0069063
TSPAN7 tetraspanin 7 -0.00689004
MYOT myotilin -0.00688896
LPIN1 lipin 1 -0.00687147
KMT2A lysine (K)-specific methyltransferase 2A -0.00685003
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.00684006
SOX4 SRY (sex determining region Y)-box 4 -0.00683728
WARS1 tryptophanyl-tRNA synthetase 1 -0.00683512
TRIB3 tribbles pseudokinase 3 -0.00683489
DSG3 desmoglein 3 -0.00680932
GRK5 G protein-coupled receptor kinase 5 -0.00679418
EXOSC10 exosome component 10 -0.00678104
TRIO trio Rho guanine nucleotide exchange factor -0.00676863
PRRC2C proline-rich coiled-coil 2C -0.00676785
C7 complement component 7 -0.006767
SCGN secretagogin, EF-hand calcium binding protein -0.00676666