PDGFRB Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description platelet-derived growth factor receptor, beta polypeptide|This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5159)
External Link https://ncbi.nlm.nih.gov/gene/5159
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Genes

499 genes differentially expressed following the PDGFRB gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
GNAS GNAS complex locus 0.0248358
ANXA1 annexin A1 0.0220438
EIF5A eukaryotic translation initiation factor 5A 0.0198386
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.0189597
TFPI2 tissue factor pathway inhibitor 2 0.0187837
SYNGR3 synaptogyrin 3 0.0186204
NIBAN1 niban apoptosis regulator 1 0.0183811
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.0183572
RGS4 regulator of G-protein signaling 4 0.0177018
THBS2 thrombospondin 2 0.0176234
IFI27 interferon, alpha-inducible protein 27 0.0162825
RELN reelin 0.0161058
SRPX sushi-repeat containing protein, X-linked 0.015802
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.0149008
SCGB2A1 secretoglobin, family 2A, member 1 0.0146143
MMP7 matrix metallopeptidase 7 0.0145708
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.0145567
DEFB1 defensin, beta 1 0.0145112
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.0142696
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.0141742
VCAN versican 0.0138273
PEG3 paternally expressed 3 0.0137592
CFI complement factor I 0.0137517
TPBG trophoblast glycoprotein 0.0132701
ASRGL1 asparaginase like 1 0.0132455
KRT23 keratin 23, type I 0.0132063
HTRA1 HtrA serine peptidase 1 0.0131544
MBD1 methyl-CpG binding domain protein 1 0.0130808
DMD dystrophin 0.0130386
CP ceruloplasmin (ferroxidase) 0.0127273
WFDC2 WAP four-disulfide core domain 2 0.0127189
PLAT plasminogen activator, tissue 0.0126677
C3 complement component 3 0.0126626
TUBA1A tubulin, alpha 1a 0.0125871
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 0.0125804
THBS1 thrombospondin 1 0.0125564
CFB complement factor B 0.0125342
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.0124564
MEIS1 Meis homeobox 1 0.0124143
IFI16 interferon, gamma-inducible protein 16 0.0124065
PLLP plasmolipin 0.0123986
PTN pleiotrophin 0.0123897
FN1 fibronectin 1 0.0123883
PLK2 polo-like kinase 2 0.0122944
AKAP12 A kinase (PRKA) anchor protein 12 0.0122841
LGALS1 lectin, galactoside-binding, soluble, 1 0.012183
IFI6 interferon, alpha-inducible protein 6 0.0121393
NPY1R neuropeptide Y receptor Y1 0.0118396
COCH cochlin 0.0117448
NID1 nidogen 1 0.0116791
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.0116598
PADI2 peptidyl arginine deiminase, type II 0.0116223
NCALD neurocalcin delta 0.0115871
DLK1 delta-like 1 homolog (Drosophila) 0.0115525
AHR aryl hydrocarbon receptor 0.0115299
COL4A5 collagen, type IV, alpha 5 0.0114514
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.011441
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.0114315
C1ORF54 chromosome 1 open reading frame 54 0.0114184
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0114182
TM9SF3 transmembrane 9 superfamily member 3 0.0112557
BAMBI BMP and activin membrane-bound inhibitor 0.0112466
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.0111486
ZFPM2 zinc finger protein, FOG family member 2 0.0109062
DPYD dihydropyrimidine dehydrogenase 0.0108571
PROM1 prominin 1 0.010791
TAGLN2 transgelin 2 0.0107649
ITM2A integral membrane protein 2A 0.010629
MUC16 mucin 16, cell surface associated 0.0106159
DCN decorin 0.0105772
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.010503
A2M alpha-2-macroglobulin 0.0104394
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.0104118
SORBS1 sorbin and SH3 domain containing 1 0.010337
TAC1 tachykinin, precursor 1 0.0102937
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.0101315
PRAME preferentially expressed antigen in melanoma 0.0101309
ALCAM activated leukocyte cell adhesion molecule 0.01013
CD302 CD302 molecule 0.0100696
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.0100564
LRRC17 leucine rich repeat containing 17 0.0100066
SCG5 secretogranin V 0.00999953
RTN1 reticulon 1 0.00999398
ELOVL2 ELOVL fatty acid elongase 2 0.00993815
CLEC11A C-type lectin domain family 11, member A 0.00993708
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 0.00981292
SPATS2L spermatogenesis associated, serine-rich 2-like 0.00980644
PNMA2 paraneoplastic Ma antigen 2 0.00979718
TAPBP TAP binding protein (tapasin) 0.00976937
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.00975545
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.00971799
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00967901
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 0.00961032
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.0095482
MYO1C myosin IC 0.00954788
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.00952698
VLDLR very low density lipoprotein receptor 0.00951728
ATXN1 ataxin 1 0.0094486
FZD6 frizzled class receptor 6 0.00942083
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 0.00937832
COL3A1 collagen, type III, alpha 1 0.00937393
WWTR1 WW domain containing transcription regulator 1 0.00935676
TMEM35 transmembrane protein 35 0.00934199
JAG1 jagged 1 0.00933915
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene 0.0093139
HCRTR1 hypocretin (orexin) receptor 1 0.00931157
NRCAM neuronal cell adhesion molecule 0.00931009
MEN1 multiple endocrine neoplasia I 0.00929972
DKK3 dickkopf WNT signaling pathway inhibitor 3 0.00927721
ARHGAP15 Rho GTPase activating protein 15 0.00922743
ASPN asporin 0.00920204
TATDN2 TatD DNase domain containing 2 0.00913826
NCKAP1L NCK-associated protein 1-like 0.00913805
PRKCA protein kinase C, alpha 0.00912707
NRN1 neuritin 1 0.00908565
SGCE sarcoglycan, epsilon 0.00908204
COL9A3 collagen, type IX, alpha 3 0.00907887
LAMB1 laminin, beta 1 0.00907026
LARP6 La ribonucleoprotein domain family, member 6 0.00906179
FLRT3 fibronectin leucine rich transmembrane protein 3 0.00904775
HSPA12A heat shock 70kDa protein 12A 0.00903574
PTHLH parathyroid hormone-like hormone 0.00902434
COL6A1 collagen, type VI, alpha 1 0.00902129
ACTG2 actin, gamma 2, smooth muscle, enteric 0.00893957
TPPP3 tubulin polymerization-promoting protein family member 3 0.0089251
NID2 nidogen 2 (osteonidogen) 0.00889497
COL6A2 collagen, type VI, alpha 2 0.00887059
TARBP1 TAR (HIV-1) RNA binding protein 1 0.00884935
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00884214
ATF3 activating transcription factor 3 0.00883591
AREG amphiregulin 0.00873264
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 0.00871807
SOBP sine oculis binding protein homolog (Drosophila) 0.0086989
CLIC4 chloride intracellular channel 4 0.00867294
CD200 CD200 molecule 0.00862395
TSPYL5 TSPY-like 5 0.00862165
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00858293
GPM6B glycoprotein M6B 0.00857419
LOXL2 lysyl oxidase-like 2 0.00855845
COBL cordon-bleu WH2 repeat protein 0.00854792
SNAP25 synaptosomal-associated protein, 25kDa 0.00852955
ACAT1 acetyl-CoA acetyltransferase 1 0.00852249
PRNP prion protein 0.00850656
AZIN1 antizyme inhibitor 1 0.0084624
CFH complement factor H 0.00845888
COL6A3 collagen, type VI, alpha 3 0.00843866
FABP7 fatty acid binding protein 7, brain 0.00842691
SCN3A sodium channel, voltage gated, type III alpha subunit 0.00839814
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.00839278
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.00836755
ARHGAP29 Rho GTPase activating protein 29 0.00835702
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.00835402
CST3 cystatin C 0.00833223
PALMD palmdelphin 0.00829934
TUBB6 tubulin, beta 6 class V 0.008279
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 0.00827624
HOMER3 homer scaffolding protein 3 0.00826522
DCHS1 dachsous cadherin-related 1 0.00823516
HSPA1A heat shock 70kDa protein 1A 0.00820978
TUBB2B tubulin, beta 2B class IIb 0.00820482
CTSD cathepsin D 0.00819963
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00818828
PFN2 profilin 2 0.00818018
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.0081569
TOX thymocyte selection-associated high mobility group box 0.0081482
MICB MHC class I polypeptide-related sequence B 0.00814244
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 0.00811616
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00806525
BAD BCL2-associated agonist of cell death 0.00803947
IRAK3 interleukin-1 receptor-associated kinase 3 0.00803619
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 0.0080063
FAM171A1 family with sequence similarity 171, member A1 0.00798506
ITPRID2 ITPR interacting domain containing 2 0.00793403
ZIC1 Zic family member 1 0.00793355
FHL1 four and a half LIM domains 1 0.0079285
TMX4 thioredoxin-related transmembrane protein 4 0.00789508
SYT11 synaptotagmin XI 0.00788933
HDAC9 histone deacetylase 9 0.0078775
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.007865
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00786342
PTDSS1 phosphatidylserine synthase 1 0.0078581
TAGLN3 transgelin 3 0.00785682
BEX1 brain expressed, X-linked 1 0.00784346
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.00784012
ZBTB10 zinc finger and BTB domain containing 10 0.00783929
IPO13 importin 13 0.00783873
AHCY adenosylhomocysteinase 0.00782211
FAIM2 Fas apoptotic inhibitory molecule 2 0.00781633
FGF1 fibroblast growth factor 1 (acidic) 0.00781054
CPVL carboxypeptidase, vitellogenic-like 0.00780513
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.00779415
HBB hemoglobin, beta 0.0077879
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 0.0077819
SVIL supervillin 0.00777593
STEAP3 STEAP family member 3, metalloreductase 0.00775928
FGF13 fibroblast growth factor 13 0.00770443
APOC2 apolipoprotein C-II 0.00766332
SYBU syntabulin (syntaxin-interacting) 0.00766175
HNRNPL heterogeneous nuclear ribonucleoprotein L 0.0076591
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.00765602
SORBS2 sorbin and SH3 domain containing 2 0.00764742
FDX1 ferredoxin 1 0.00763236
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.00761509
SV2A synaptic vesicle glycoprotein 2A 0.00761279
IL1RAP interleukin 1 receptor accessory protein 0.00760698
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 0.0075851
TUBB2A tubulin, beta 2A class IIa 0.00758275
MOXD1 monooxygenase, DBH-like 1 0.00757721
NRXN3 neurexin 3 0.00757344
NCAM1 neural cell adhesion molecule 1 0.00755859
PCP4 Purkinje cell protein 4 0.00755574
SH2B3 SH2B adaptor protein 3 0.00755428
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 0.00754398
CSRP1 cysteine and glycine-rich protein 1 0.00752513
F2R coagulation factor II (thrombin) receptor 0.00752323
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 0.00751256
CRP C-reactive protein, pentraxin-related 0.00750328
NELL1 NEL-like 1 (chicken) 0.00750314
AMACR alpha-methylacyl-CoA racemase 0.00750204
SELPLG selectin P ligand 0.00747569
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00746408
RAI14 retinoic acid induced 14 0.00746385
MLF1 myeloid leukemia factor 1 0.00745607
HMGA1 high mobility group AT-hook 1 0.00744513
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.00742179
PLTP phospholipid transfer protein 0.00741771
CXCL12 chemokine (C-X-C motif) ligand 12 0.00741046
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00737075
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 0.00735063
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) 0.00733663
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.00732746
NME5 NME/NM23 family member 5 0.0073034
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00729051
SYT1 synaptotagmin I 0.00729002
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 0.00727697
GNG3 guanine nucleotide binding protein (G protein), gamma 3 0.00726926
TJP2 tight junction protein 2 0.00725141
DCPS decapping enzyme, scavenger 0.00724018
TSPYL4 TSPY-like 4 0.00723206
MOAP1 modulator of apoptosis 1 0.00722591
BCHE butyrylcholinesterase 0.00720937
RNF130 ring finger protein 130 0.00720917
UBE3A ubiquitin protein ligase E3A 0.00719529
F3 coagulation factor III (thromboplastin, tissue factor) 0.00718555
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.00718157
HSPA8 heat shock 70kDa protein 8 0.00718116
ISG15 ISG15 ubiquitin-like modifier 0.00715613
CD4 CD4 molecule 0.00714833
SECTM1 secreted and transmembrane 1 0.00712482
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha 0.00712079

decreased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 -0.0279876
MALL mal, T-cell differentiation protein-like -0.0174174
AMDHD2 amidohydrolase domain containing 2 -0.0171285
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.0171082
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0170777
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.0152598
ZDHHC6 zinc finger, DHHC-type containing 6 -0.0152285
SIRT3 sirtuin 3 -0.0149283
ADIRF adipogenesis regulatory factor -0.0148567
CTNND1 catenin (cadherin-associated protein), delta 1 -0.0147174
HOPX HOP homeobox -0.0137646
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.0131782
HOXC6 homeobox C6 -0.0128661
KRT16 keratin 16, type I -0.0123024
TSPAN13 tetraspanin 13 -0.0122159
CD40 CD40 molecule, TNF receptor superfamily member 5 -0.0122021
CRABP2 cellular retinoic acid binding protein 2 -0.012037
WSB1 WD repeat and SOCS box containing 1 -0.0118245
TM4SF20 transmembrane 4 L six family member 20 -0.0115039
SPRR2B small proline-rich protein 2B -0.0113903
PON3 paraoxonase 3 -0.0113309
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -0.0111909
COMP cartilage oligomeric matrix protein -0.0111345
RHOB ras homolog family member B -0.0109144
AIM2 absent in melanoma 2 -0.0107954
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -0.0107831
CRCT1 cysteine-rich C-terminal 1 -0.0106982
CXCL14 chemokine (C-X-C motif) ligand 14 -0.0106396
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.0106164
FZD5 frizzled class receptor 5 -0.010604
CXCL13 chemokine (C-X-C motif) ligand 13 -0.0105894
NDNF neuron-derived neurotrophic factor -0.0103742
CXCL9 chemokine (C-X-C motif) ligand 9 -0.0103419
SPRR1A small proline-rich protein 1A -0.0103305
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.0102645
CST6 cystatin E/M -0.0101905
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.0100214
CD79B CD79b molecule, immunoglobulin-associated beta -0.010011
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0100077
SFTPB surfactant protein B -0.00997202
RBM47 RNA binding motif protein 47 -0.00988778
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase -0.00985436
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00962413
VAMP8 vesicle-associated membrane protein 8 -0.00957535
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.00953919
RHCG Rh family, C glycoprotein -0.00948661
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -0.0094674
ZNF586 zinc finger protein 586 -0.00941763
BANK1 B-cell scaffold protein with ankyrin repeats 1 -0.00938895
S100A12 S100 calcium binding protein A12 -0.00934504
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha -0.00930217
GAL galanin/GMAP prepropeptide -0.00927035
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon -0.00924356
SPRR1B small proline-rich protein 1B -0.00916185
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00912387
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00909765
LY6D lymphocyte antigen 6 complex, locus D -0.00900917
RAB38 RAB38, member RAS oncogene family -0.00897847
ABLIM1 actin binding LIM protein 1 -0.00894475
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.00893185
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00890149
EZR ezrin -0.00888447
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.00885781
TPSAB1 tryptase alpha/beta 1 -0.00885465
PPL periplakin -0.00875767
NPR3 natriuretic peptide receptor 3 -0.00870853
CTBP2 C-terminal binding protein 2 -0.00866451
LYPD3 LY6/PLAUR domain containing 3 -0.00864971
CDH3 cadherin 3, type 1, P-cadherin (placental) -0.00863754
TPD52 tumor protein D52 -0.00863512
DUOX2 dual oxidase 2 -0.00856107
AHCYL1 adenosylhomocysteinase-like 1 -0.00851037
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.00848886
NKX2-1 NK2 homeobox 1 -0.00847103
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.00844584
CRISP3 cysteine-rich secretory protein 3 -0.00843772
RASIP1 Ras interacting protein 1 -0.00837738
STX3 syntaxin 3 -0.00836838
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -0.00835742
VPREB3 pre-B lymphocyte 3 -0.00829206
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -0.00822969
MUC4 mucin 4, cell surface associated -0.00819797
DSG3 desmoglein 3 -0.00819141
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.00818877
MYO5C myosin VC -0.00812044
TCL1A T-cell leukemia/lymphoma 1A -0.008065
CDH17 cadherin 17, LI cadherin (liver-intestine) -0.00803884
EPHX3 epoxide hydrolase 3 -0.00802783
S100A9 S100 calcium binding protein A9 -0.00800373
ELN elastin -0.00799008
CLCN3 chloride channel, voltage-sensitive 3 -0.00794908
SOCS1 suppressor of cytokine signaling 1 -0.00794248
LGALS4 lectin, galactoside-binding, soluble, 4 -0.0079406
UNC13B unc-13 homolog B (C. elegans) -0.00792144
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -0.00791997
CDA cytidine deaminase -0.00787938
EPHB2 EPH receptor B2 -0.00784854
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -0.00783974
GAB2 GRB2-associated binding protein 2 -0.00780617
TIMP3 TIMP metallopeptidase inhibitor 3 -0.0077755
ASS1 argininosuccinate synthase 1 -0.00776642
MAMLD1 mastermind-like domain containing 1 -0.00772718
NARF nuclear prelamin A recognition factor -0.00768839
SPINK4 serine peptidase inhibitor, Kazal type 4 -0.00768555
MMP12 matrix metallopeptidase 12 -0.0076767
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -0.00765292
TMPRSS11E transmembrane protease, serine 11E -0.00765023
PDZK1IP1 PDZK1 interacting protein 1 -0.0076109
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 -0.00760748
RAB25 RAB25, member RAS oncogene family -0.00757536
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 -0.00753436
SLAMF7 SLAM family member 7 -0.00752235
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) -0.00744486
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.00741032
CLC Charcot-Leyden crystal galectin -0.00739272
DPP4 dipeptidyl-peptidase 4 -0.00734093
SIK1 salt-inducible kinase 1 -0.00729583
TMPRSS2 transmembrane protease, serine 2 -0.00727357
H1-0 H1.0 linker histone -0.00726548
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -0.0072185
PHACTR2 phosphatase and actin regulator 2 -0.00721523
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.00714661
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase -0.00713719
BLNK B-cell linker -0.00710598
PAEP progestagen-associated endometrial protein -0.0071058
ANOS1 anosmin 1 -0.00710558
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 -0.00710054
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.00705993
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -0.00705598
FABP4 fatty acid binding protein 4, adipocyte -0.00703236
SI sucrase-isomaltase (alpha-glucosidase) -0.00703179
DSG1 desmoglein 1 -0.00702938
SOWAHC sosondowah ankyrin repeat domain family member C -0.00701932
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -0.00701366
MYO6 myosin VI -0.00699857
REG3A regenerating islet-derived 3 alpha -0.00697628
CIAO3 cytosolic iron-sulfur assembly component 3 -0.00695099
BAG1 BCL2-associated athanogene -0.00693858
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 -0.00693826
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -0.00692791
L1TD1 LINE-1 type transposase domain containing 1 -0.00688941
AHDC1 AT hook, DNA binding motif, containing 1 -0.00687369
MXI1 MAX interactor 1, dimerization protein -0.00687019
GTF2IRD1 GTF2I repeat domain containing 1 -0.00686818
CA12 carbonic anhydrase XII -0.00686345
IVL involucrin -0.00684164
SCEL sciellin -0.00683683
TTC39A tetratricopeptide repeat domain 39A -0.00681322
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) -0.00680782
SLC38A1 solute carrier family 38, member 1 -0.00679905
DOCK9 dedicator of cytokinesis 9 -0.00679385
CLDN4 claudin 4 -0.00676891
AKT1 v-akt murine thymoma viral oncogene homolog 1 -0.00675285
EMP2 epithelial membrane protein 2 -0.00674822
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 -0.00673445
ZNF185 zinc finger protein 185 (LIM domain) -0.00673278
SEPTIN10 septin 10 -0.00671345
INSR insulin receptor -0.00668697
S100A2 S100 calcium binding protein A2 -0.00667722
CRNN cornulin -0.00667705
NXN nucleoredoxin -0.00666319
FUCA1 fucosidase, alpha-L- 1, tissue -0.00664973
SLC16A6 solute carrier family 16, member 6 -0.0066243
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.00659778
EPHX2 epoxide hydrolase 2, cytoplasmic -0.00659064
S100A7 S100 calcium binding protein A7 -0.00658512
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 -0.00658168
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.00656412
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 -0.00655159
CXCL11 chemokine (C-X-C motif) ligand 11 -0.00654921
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 -0.00654406
VAMP5 vesicle-associated membrane protein 5 -0.00653452
MET MET proto-oncogene, receptor tyrosine kinase -0.00651422
MID1 midline 1 -0.00650871
PYCARD PYD and CARD domain containing -0.00650723
TMEM126B transmembrane protein 126B -0.0064845
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) -0.00648341
GLS glutaminase -0.00648247
APOA4 apolipoprotein A-IV -0.00646384
TK1 thymidine kinase 1, soluble -0.0064629
UBE2I ubiquitin-conjugating enzyme E2I -0.00646064
NBL1 neuroblastoma 1, DAN family BMP antagonist -0.00645681
ARPP19 cAMP-regulated phosphoprotein, 19kDa -0.00645105
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00643611
FLNB filamin B, beta -0.00643393
MXD1 MAX dimerization protein 1 -0.00643018
FASTKD1 FAST kinase domains 1 -0.00642469
KLK10 kallikrein-related peptidase 10 -0.00641379
UBL3 ubiquitin-like 3 -0.00639476
DHRS11 dehydrogenase/reductase (SDR family) member 11 -0.00637928
DVL1 dishevelled segment polarity protein 1 -0.00637366
CD9 CD9 molecule -0.00635478
INHBB inhibin, beta B -0.00635428
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 -0.00634991
GUCY2C guanylate cyclase 2C -0.00634319
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) -0.00633007
CR2 complement component (3d/Epstein Barr virus) receptor 2 -0.00632176
PROCR protein C receptor, endothelial -0.00630653
C1ORF116 chromosome 1 open reading frame 116 -0.00629756
NIT1 nitrilase 1 -0.00628102
CYTIP cytohesin 1 interacting protein -0.00627199
MRPS34 mitochondrial ribosomal protein S34 -0.00626481
CSTB cystatin B (stefin B) -0.00626125
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.00621724
REG1A regenerating islet-derived 1 alpha -0.00621247
ZBTB18 zinc finger and BTB domain containing 18 -0.00620072
MICU2 mitochondrial calcium uptake 2 -0.00619245
CERK ceramide kinase -0.00618813
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) -0.00618417
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) -0.00616591
DSC2 desmocollin 2 -0.00616305
MMP3 matrix metallopeptidase 3 -0.00613055
LRRC15 leucine rich repeat containing 15 -0.00612876
PDK4 pyruvate dehydrogenase kinase, isozyme 4 -0.00612188
CCL8 chemokine (C-C motif) ligand 8 -0.00611427
ERBB3 erb-b2 receptor tyrosine kinase 3 -0.0061108
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog -0.00610549
TSC2 tuberous sclerosis 2 -0.00610544
PLXNB2 plexin B2 -0.00610189
KLK7 kallikrein-related peptidase 7 -0.00608924
CCNG2 cyclin G2 -0.00608581
FCRL2 Fc receptor-like 2 -0.00607207
KLK12 kallikrein-related peptidase 12 -0.00606332
STEAP4 STEAP family member 4 -0.00605859
GLO1 glyoxalase I -0.0060566
GTPBP1 GTP binding protein 1 -0.00605634
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O -0.00604217
ELOB elongin B -0.00604208
UXT ubiquitously-expressed, prefoldin-like chaperone -0.00603011
EHD2 EH-domain containing 2 -0.00602172
ACTN4 actinin, alpha 4 -0.00601835
CPA3 carboxypeptidase A3 (mast cell) -0.00600906
USP48 ubiquitin specific peptidase 48 -0.00600757
FBP1 fructose-1,6-bisphosphatase 1 -0.0060043
TBC1D16 TBC1 domain family, member 16 -0.00599897
NLRP2 NLR family, pyrin domain containing 2 -0.00598659
TNK2 tyrosine kinase, non-receptor, 2 -0.00598425
OLFM4 olfactomedin 4 -0.00597682
TGM1 transglutaminase 1 -0.00597344
BMP2 bone morphogenetic protein 2 -0.0059556
TGM3 transglutaminase 3 -0.0059526
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae) -0.00594469
KRT81 keratin 81, type II -0.00590589
MDFIC MyoD family inhibitor domain containing -0.00590258
CD19 CD19 molecule -0.00590136
MAGEA11 melanoma antigen family A11 -0.00587834
MTL5 metallothionein-like 5, testis-specific (tesmin) -0.00587318
EVPL envoplakin -0.00586841
LAMB3 laminin, beta 3 -0.00586535