| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | pyruvate dehydrogenase kinase, isozyme 2|This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010] (NCBI Entrez Gene Database, 5164) |
| External Link | https://ncbi.nlm.nih.gov/gene/5164 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the PDK2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| S100A9 | S100 calcium binding protein A9 | 0.0189782 |
| S100A8 | S100 calcium binding protein A8 | 0.0183865 |
| LCN2 | lipocalin 2 | 0.0172178 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0151972 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.0147504 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.0140919 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0139659 |
| KRT14 | keratin 14, type I | 0.0136571 |
| ECM1 | extracellular matrix protein 1 | 0.01311 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.013066 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.0130583 |
| XIC | X chromosome inactivation center | 0.0128225 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0125865 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0121492 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0121063 |
| S100A12 | S100 calcium binding protein A12 | 0.0117514 |
| HSPA2 | heat shock 70kDa protein 2 | 0.0116144 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.0113888 |
| ADD3 | adducin 3 (gamma) | 0.0113758 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.011005 |
| ADM | adrenomedullin | 0.0109997 |
| ATF3 | activating transcription factor 3 | 0.0109459 |
| RHOB | ras homolog family member B | 0.0109454 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0108939 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.0105946 |
| IFI44L | interferon-induced protein 44-like | 0.0105836 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.0105808 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0105765 |
| KLK5 | kallikrein-related peptidase 5 | 0.0104032 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0103968 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.010367 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.0102759 |
| TUFT1 | tuftelin 1 | 0.0101843 |
| IFI44 | interferon-induced protein 44 | 0.00987481 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00978827 |
| TUBB2B | tubulin, beta 2B class IIb | 0.00968395 |
| PIP | prolactin-induced protein | 0.00965749 |
| DIPK1A | divergent protein kinase domain 1A | 0.00962702 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.00960989 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00957352 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00949852 |
| HBEGF | heparin-binding EGF-like growth factor | 0.00945648 |
| HMOX1 | heme oxygenase 1 | 0.00929367 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.00923337 |
| KLK10 | kallikrein-related peptidase 10 | 0.00919223 |
| KLF6 | Kruppel-like factor 6 | 0.00915697 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00913856 |
| CLEC2B | C-type lectin domain family 2, member B | 0.00902171 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.00901509 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.00899813 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00899062 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00894093 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00891552 |
| EVI2A | ecotropic viral integration site 2A | 0.00887319 |
| RCAN1 | regulator of calcineurin 1 | 0.00885078 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.00884857 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.0087712 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.00872308 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00862976 |
| KRT23 | keratin 23, type I | 0.00858775 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.00858617 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.00855292 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00842894 |
| PLK2 | polo-like kinase 2 | 0.00842222 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.00842109 |
| INHBA | inhibin, beta A | 0.00840382 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00837186 |
| CYTIP | cytohesin 1 interacting protein | 0.00831575 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00831415 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.00815996 |
| PEG10 | paternally expressed 10 | 0.00813788 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | 0.00813074 |
| CSTA | cystatin A (stefin A) | 0.00803566 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0080223 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00800501 |
| WLS | wntless Wnt ligand secretion mediator | 0.00799534 |
| PERP | PERP, TP53 apoptosis effector | 0.00798981 |
| KLF2 | Kruppel-like factor 2 | 0.00795486 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00793707 |
| ACKR3 | atypical chemokine receptor 3 | 0.00793131 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00793106 |
| MAL | mal, T-cell differentiation protein | 0.00788833 |
| CALML3 | calmodulin-like 3 | 0.00787594 |
| TWIST1 | twist family bHLH transcription factor 1 | 0.00785488 |
| USP18 | ubiquitin specific peptidase 18 | 0.00784185 |
| S100A7 | S100 calcium binding protein A7 | 0.00782932 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00782622 |
| CFB | complement factor B | 0.00781572 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00781162 |
| FOSL2 | FOS-like antigen 2 | 0.00779357 |
| MCL1 | myeloid cell leukemia 1 | 0.00778905 |
| RRAGD | Ras-related GTP binding D | 0.00777975 |
| TCTA | T-cell leukemia translocation altered | 0.00776665 |
| NDRG1 | N-myc downstream regulated 1 | 0.00766375 |
| CCN2 | cellular communication network factor 2 | 0.00759609 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.00759005 |
| ELANE | elastase, neutrophil expressed | 0.00758405 |
| ABLIM1 | actin binding LIM protein 1 | 0.00754293 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.00753538 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00752153 |
| MME | membrane metallo-endopeptidase | 0.00749314 |
| GAB2 | GRB2-associated binding protein 2 | 0.00748607 |
| MX2 | MX dynamin-like GTPase 2 | 0.00748188 |
| PXDN | peroxidasin | 0.00746971 |
| RGS4 | regulator of G-protein signaling 4 | 0.00743443 |
| STX3 | syntaxin 3 | 0.00740879 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | 0.00740239 |
| GPR137B | G protein-coupled receptor 137B | 0.00739048 |
| ANXA3 | annexin A3 | 0.00736702 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.00736212 |
| LAMB1 | laminin, beta 1 | 0.00733752 |
| PODXL | podocalyxin-like | 0.00733311 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | 0.00732165 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | 0.00729727 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | 0.0072858 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00728418 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00726968 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00724793 |
| CCNA2 | cyclin A2 | 0.00723606 |
| EDNRB | endothelin receptor type B | 0.00722739 |
| STK10 | serine/threonine kinase 10 | 0.00721355 |
| NEU1 | sialidase 1 (lysosomal sialidase) | 0.00719727 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0071375 |
| GSDMB | gasdermin B | 0.00713292 |
| APOD | apolipoprotein D | 0.0071259 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0071242 |
| FRS2 | fibroblast growth factor receptor substrate 2 | 0.00710334 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00709401 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.00707684 |
| IL1B | interleukin 1, beta | 0.00701475 |
| DCN | decorin | 0.00701376 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00700839 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | 0.00699074 |
| RNF167 | ring finger protein 167 | 0.00698896 |
| KLK11 | kallikrein-related peptidase 11 | 0.00697837 |
| AMOTL2 | angiomotin like 2 | 0.00697242 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.00697192 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.00695205 |
| IFITM2 | interferon induced transmembrane protein 2 | 0.00695196 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | 0.00694595 |
| MCAM | melanoma cell adhesion molecule | 0.00691405 |
| GATA6 | GATA binding protein 6 | 0.00690698 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00690141 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00688048 |
| LIMA1 | LIM domain and actin binding 1 | 0.00684769 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00681442 |
| MYOF | myoferlin | 0.00676443 |
| MICB | MHC class I polypeptide-related sequence B | 0.00674652 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.0067363 |
| FNDC3B | fibronectin type III domain containing 3B | 0.00673455 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.00673189 |
| SP140L | SP140 nuclear body protein-like | 0.00671545 |
| CA12 | carbonic anhydrase XII | 0.00668431 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.00668347 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | 0.00665849 |
| S100A2 | S100 calcium binding protein A2 | 0.00665566 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00663039 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00662925 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.00658635 |
| CLCA2 | chloride channel accessory 2 | 0.00656116 |
| PLIN2 | perilipin 2 | 0.0065335 |
| CA2 | carbonic anhydrase II | 0.00652426 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.0065191 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 | 0.00651395 |
| LPIN1 | lipin 1 | 0.00651112 |
| AOC1 | amine oxidase, copper containing 1 | 0.00648754 |
| FOXO1 | forkhead box O1 | 0.00648342 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.00646889 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00646782 |
| CTSV | cathepsin V | 0.00646361 |
| GPM6B | glycoprotein M6B | 0.00646258 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.00645048 |
| HK2 | hexokinase 2 | 0.0064495 |
| EFNA1 | ephrin-A1 | 0.00643346 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00640516 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.00639452 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00637808 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00634566 |
| CAPN3 | calpain 3, (p94) | 0.00634184 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | 0.00632895 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.00630539 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.00627746 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.00627501 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.00624541 |
| SOCS1 | suppressor of cytokine signaling 1 | 0.0062254 |
| CDK5R1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 0.0062246 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | 0.00622199 |
| NCF2 | neutrophil cytosolic factor 2 | 0.00620856 |
| ZFP36 | ZFP36 ring finger protein | 0.00619549 |
| ZNF395 | zinc finger protein 395 | 0.00618856 |
| FAR2 | fatty acyl CoA reductase 2 | 0.0061739 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 0.00616446 |
| MAP7 | microtubule-associated protein 7 | 0.0061536 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.00613502 |
| SP110 | SP110 nuclear body protein | 0.00613164 |
| FHL2 | four and a half LIM domains 2 | 0.00612001 |
| ASS1 | argininosuccinate synthase 1 | 0.00611293 |
| LTF | lactotransferrin | 0.00610328 |
| PLAT | plasminogen activator, tissue | 0.00609567 |
| MX1 | MX dynamin-like GTPase 1 | 0.00608784 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00607039 |
| SQSTM1 | sequestosome 1 | 0.00606096 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.00604798 |
| DACH1 | dachshund family transcription factor 1 | 0.00603683 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 | 0.00603316 |
| AUTS2 | autism susceptibility candidate 2 | 0.00603051 |
| EDN1 | endothelin 1 | 0.00602818 |
| HBB | hemoglobin, beta | 0.00602451 |
| GRAMD2B | GRAM domain containing 2B | 0.00599581 |
| QDPR | quinoid dihydropteridine reductase | 0.0059957 |
| SPRR1B | small proline-rich protein 1B | 0.00599122 |
| BCL2A1 | BCL2-related protein A1 | 0.00598837 |
| MCM2 | minichromosome maintenance complex component 2 | 0.0059847 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.0059847 |
| GRN | granulin | 0.00597435 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.00595449 |
| SCG5 | secretogranin V | 0.00595421 |
| FA2H | fatty acid 2-hydroxylase | 0.00595091 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.00594453 |
| NMRK1 | nicotinamide riboside kinase 1 | 0.00593943 |
| ADI1 | acireductone dioxygenase 1 | 0.00593428 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.00592087 |
| KRT17 | keratin 17, type I | 0.00591314 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00590861 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.0059047 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.00590289 |
| IL1RN | interleukin 1 receptor antagonist | 0.00589346 |
| CRCT1 | cysteine-rich C-terminal 1 | 0.00589041 |
| DEFB1 | defensin, beta 1 | 0.00588161 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00587889 |
| TLR4 | toll-like receptor 4 | 0.00587443 |
| ITGA6 | integrin, alpha 6 | 0.00586615 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00586599 |
| MECOM | MDS1 and EVI1 complex locus | 0.00586215 |
| RPS27L | ribosomal protein S27-like | 0.00586214 |
| MYO1B | myosin IB | 0.00585917 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | 0.00585529 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00583882 |
| MMP8 | matrix metallopeptidase 8 | 0.0058356 |
| EGR1 | early growth response 1 | 0.00582492 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.0058055 |
| TPP1 | tripeptidyl peptidase I | 0.00580417 |
| SPRR1A | small proline-rich protein 1A | 0.00578853 |
| FRMD4B | FERM domain containing 4B | 0.00576817 |
| TPM4 | tropomyosin 4 | 0.0057602 |
| CRYAB | crystallin, alpha B | 0.00575271 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00574376 |
| HLX | H2.0-like homeobox | 0.00573634 |
| OPTN | optineurin | 0.00571932 |
| TRIM29 | tripartite motif containing 29 | 0.00571776 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0192489 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.0140128 |
| ZNF589 | zinc finger protein 589 | -0.0122326 |
| MGP | matrix Gla protein | -0.0118124 |
| OLFM1 | olfactomedin 1 | -0.011132 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.0109375 |
| GATA2 | GATA binding protein 2 | -0.0101165 |
| DES | desmin | -0.00980267 |
| PRMT1 | protein arginine methyltransferase 1 | -0.00978163 |
| XPO7 | exportin 7 | -0.00969878 |
| CES1 | carboxylesterase 1 | -0.00968178 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00964711 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -0.00955665 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.00944538 |
| TNS1 | tensin 1 | -0.00923634 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00920288 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | -0.00914256 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00903327 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00897894 |
| TSPAN7 | tetraspanin 7 | -0.00893021 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00892734 |
| TSPYL5 | TSPY-like 5 | -0.00883057 |
| CST3 | cystatin C | -0.00860895 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00845044 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00843107 |
| TGM2 | transglutaminase 2 | -0.00832973 |
| ZNF532 | zinc finger protein 532 | -0.00821694 |
| RPA3 | replication protein A3, 14kDa | -0.00821058 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.00820863 |
| CTSZ | cathepsin Z | -0.00820245 |
| APOB | apolipoprotein B | -0.00816943 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00805835 |
| A2M | alpha-2-macroglobulin | -0.00805165 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00801936 |
| CHMP4A | charged multivesicular body protein 4A | -0.00780593 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.0077892 |
| PRKCB | protein kinase C, beta | -0.00773548 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.00768425 |
| HMGB1 | high mobility group box 1 | -0.00767535 |
| TMEM106B | transmembrane protein 106B | -0.00766152 |
| HHEX | hematopoietically expressed homeobox | -0.00763384 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00759119 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | -0.00756968 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.007498 |
| NEK2 | NIMA-related kinase 2 | -0.00747913 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00741594 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | -0.00740523 |
| KIAA0100 | KIAA0100 | -0.00739171 |
| WDR61 | WD repeat domain 61 | -0.00733394 |
| NIPSNAP2 | nipsnap homolog 2 | -0.00728624 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00725523 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -0.0072454 |
| HMBS | hydroxymethylbilane synthase | -0.00720466 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | -0.00717442 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.00717391 |
| FGG | fibrinogen gamma chain | -0.00712299 |
| CHRDL1 | chordin-like 1 | -0.00709992 |
| MRTFB | myocardin related transcription factor B | -0.00707729 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | -0.00707091 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | -0.00701758 |
| GPX3 | glutathione peroxidase 3 | -0.00700912 |
| CCK | cholecystokinin | -0.00698423 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.00695777 |
| ESD | esterase D | -0.00694866 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.006909 |
| ELOVL6 | ELOVL fatty acid elongase 6 | -0.00686917 |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | -0.00684598 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.00681141 |
| ZBTB16 | zinc finger and BTB domain containing 16 | -0.00676715 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | -0.00674614 |
| OIP5 | Opa interacting protein 5 | -0.00673601 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.00671864 |
| AHSG | alpha-2-HS-glycoprotein | -0.00671225 |
| COL4A6 | collagen, type IV, alpha 6 | -0.00670212 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00669599 |
| PDE8B | phosphodiesterase 8B | -0.00666985 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | -0.00662714 |
| SLC2A4RG | SLC2A4 regulator | -0.00661981 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 | -0.00658674 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.00657794 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.00657766 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -0.00657508 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00655958 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00650335 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.00649543 |
| CD320 | CD320 molecule | -0.00648897 |
| PCGF2 | polycomb group ring finger 2 | -0.00646072 |
| SORD | sorbitol dehydrogenase | -0.00645 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like | -0.00642527 |
| FECH | ferrochelatase | -0.00636546 |
| NPTXR | neuronal pentraxin receptor | -0.00636172 |
| NIBAN1 | niban apoptosis regulator 1 | -0.0063483 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | -0.006334 |
| BAG2 | BCL2-associated athanogene 2 | -0.00632675 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.00631962 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.00629732 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00629279 |
| PPAP2A | phosphatidic acid phosphatase type 2A | -0.00627942 |
| RIOX2 | ribosomal oxygenase 2 | -0.00627254 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00626779 |
| MEF2C | myocyte enhancer factor 2C | -0.00626007 |
| CCL21 | chemokine (C-C motif) ligand 21 | -0.00623721 |
| APOC2 | apolipoprotein C-II | -0.00620475 |
| AURKA | aurora kinase A | -0.00618998 |
| EXOSC7 | exosome component 7 | -0.00617953 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | -0.00617077 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | -0.00616595 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00613879 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.00613594 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 | -0.0060989 |
| XK | X-linked Kx blood group | -0.0060688 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | -0.00606277 |
| NELL1 | NEL-like 1 (chicken) | -0.0060493 |
| HMGB2 | high mobility group box 2 | -0.00604787 |
| UBE2S | ubiquitin-conjugating enzyme E2S | -0.00604019 |
| CENPX | centromere protein X | -0.00602926 |
| SHLD2 | shieldin complex subunit 2 | -0.00600853 |
| C1S | complement component 1, s subcomponent | -0.00600522 |
| THSD7A | thrombospondin, type I, domain containing 7A | -0.00599586 |
| BAD | BCL2-associated agonist of cell death | -0.00598326 |
| CRIP2 | cysteine-rich protein 2 | -0.00597833 |
| SEPTIN6 | septin 6 | -0.00596779 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.00596214 |
| LTBP4 | latent transforming growth factor beta binding protein 4 | -0.0059504 |
| MRPL12 | mitochondrial ribosomal protein L12 | -0.00593314 |
| FHL1 | four and a half LIM domains 1 | -0.00593086 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.00591915 |
| KLK2 | kallikrein-related peptidase 2 | -0.00591478 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | -0.0059099 |
| CCNF | cyclin F | -0.00590137 |
| NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 | -0.00588276 |
| LMOD1 | leiomodin 1 (smooth muscle) | -0.00587228 |
| ASPN | asporin | -0.00587042 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | -0.00586298 |
| FGB | fibrinogen beta chain | -0.00586028 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00585519 |
| GPC3 | glypican 3 | -0.00583946 |
| KRT19 | keratin 19, type I | -0.00583564 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0058107 |
| SELENOW | selenoprotein W | -0.00580768 |
| NPY1R | neuropeptide Y receptor Y1 | -0.00579398 |
| DBF4 | DBF4 zinc finger | -0.00578318 |
| AFP | alpha-fetoprotein | -0.0057766 |
| LEPR | leptin receptor | -0.00574465 |
| MYBPC1 | myosin binding protein C, slow type | -0.00572172 |
| THYN1 | thymocyte nuclear protein 1 | -0.00571862 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00571778 |
| ELN | elastin | -0.0056681 |
| SIAH1 | siah E3 ubiquitin protein ligase 1 | -0.00565625 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00562856 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | -0.00562352 |
| C1R | complement component 1, r subcomponent | -0.00561002 |
| KIAA0232 | KIAA0232 | -0.00560199 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00559853 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.00559369 |
| MPHOSPH9 | M-phase phosphoprotein 9 | -0.00558999 |
| CRLF1 | cytokine receptor-like factor 1 | -0.00558126 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | -0.00557923 |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | -0.00556915 |
| PLN | phospholamban | -0.00556699 |
| FADS1 | fatty acid desaturase 1 | -0.00556449 |
| DMAC2L | distal membrane arm assembly component 2 like | -0.00556352 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.0055481 |
| ZNF512B | zinc finger protein 512B | -0.00553492 |
| CADM1 | cell adhesion molecule 1 | -0.00553466 |
| ISOC2 | isochorismatase domain containing 2 | -0.00552731 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.00551968 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 | -0.00550346 |
| TPM2 | tropomyosin 2 (beta) | -0.00549954 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00549894 |
| GZMK | granzyme K (granzyme 3; tryptase II) | -0.00548564 |
| CNN1 | calponin 1, basic, smooth muscle | -0.00542225 |
| NUP37 | nucleoporin 37kDa | -0.00540803 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 | -0.00540432 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.00538509 |
| COPS7A | COP9 signalosome subunit 7A | -0.00538369 |
| RPS5 | ribosomal protein S5 | -0.00536757 |
| CAPN6 | calpain 6 | -0.00535848 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.00535824 |
| ISCA1 | iron-sulfur cluster assembly 1 | -0.00532685 |
| RBM38 | RNA binding motif protein 38 | -0.00531794 |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | -0.00530346 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.00529664 |
| COMMD8 | COMM domain containing 8 | -0.00529444 |
| CP | ceruloplasmin (ferroxidase) | -0.00529047 |
| DIXDC1 | DIX domain containing 1 | -0.0052809 |
| PRELP | proline/arginine-rich end leucine-rich repeat protein | -0.0052783 |
| BID | BH3 interacting domain death agonist | -0.00527419 |
| STEAP3 | STEAP family member 3, metalloreductase | -0.0052704 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) | -0.0052641 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.00526097 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 | -0.00523504 |
| TCEA1 | transcription elongation factor A (SII), 1 | -0.00522043 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 | -0.00521186 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.00521146 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | -0.00521103 |
| CNOT7 | CCR4-NOT transcription complex, subunit 7 | -0.00520762 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | -0.00520399 |
| NCAM1 | neural cell adhesion molecule 1 | -0.00520318 |
| PBK | PDZ binding kinase | -0.00519799 |
| FGA | fibrinogen alpha chain | -0.00518263 |
| KLK3 | kallikrein-related peptidase 3 | -0.00517451 |
| TRAPPC4 | trafficking protein particle complex 4 | -0.00517235 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C | -0.00517108 |
| IPO5 | importin 5 | -0.00516587 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00516584 |
| KIF2C | kinesin family member 2C | -0.00516457 |
| PAK1IP1 | PAK1 interacting protein 1 | -0.00516206 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.00515902 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.00515875 |
| FAM216A | family with sequence similarity 216, member A | -0.00515783 |
| UBL4A | ubiquitin-like 4A | -0.00515318 |
| NUP93 | nucleoporin 93kDa | -0.00514537 |
| FLOT2 | flotillin 2 | -0.00513505 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0051254 |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) | -0.0051253 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00511846 |
| PWP1 | PWP1 homolog (S. cerevisiae) | -0.00511742 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00511036 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | -0.00510842 |
| DMTN | dematin actin binding protein | -0.00509829 |
| RELN | reelin | -0.00508091 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | -0.00505918 |
| CUTC | cutC copper transporter | -0.00505265 |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 | -0.00504464 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) | -0.00503722 |
| TRIP13 | thyroid hormone receptor interactor 13 | -0.00503441 |
| FASTKD3 | FAST kinase domains 3 | -0.0050328 |
| PEG3 | paternally expressed 3 | -0.00502048 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00502044 |
| AMD1 | adenosylmethionine decarboxylase 1 | -0.00502033 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.00500131 |
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 | -0.00500007 |
| ITIH3 | inter-alpha-trypsin inhibitor heavy chain 3 | -0.00499645 |
| ACACA | acetyl-CoA carboxylase alpha | -0.00498849 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 | -0.00497227 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | -0.00497094 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | -0.00496952 |
| CD151 | CD151 molecule (Raph blood group) | -0.0049663 |
| CLEC10A | C-type lectin domain family 10, member A | -0.00496005 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00495829 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.00495777 |
| NDRG3 | NDRG family member 3 | -0.00495479 |
| RANBP1 | RAN binding protein 1 | -0.00494593 |
| THAP11 | THAP domain containing 11 | -0.00494227 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -0.00493004 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.00492327 |
| NKX3-1 | NK3 homeobox 1 | -0.00491967 |
| SMYD2 | SET and MYND domain containing 2 | -0.00491582 |
| LBR | lamin B receptor | -0.00491213 |
