PDK2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description pyruvate dehydrogenase kinase, isozyme 2|This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010] (NCBI Entrez Gene Database, 5164)
External Link http://www.ncbi.nlm.nih.gov/gene/5164
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Genes

17 interacting proteins for PDK2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
CTTN cortactin
DLAT dihydrolipoamide S-acetyltransferase
DLD dihydrolipoamide dehydrogenase
HIC2 hypermethylated in cancer 2
HNF4A hepatocyte nuclear factor 4, alpha
HTT huntingtin
ISOC2 isochorismatase domain containing 2
MAX MYC associated factor X
MYC v-myc avian myelocytomatosis viral oncogene homolog
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PDHB pyruvate dehydrogenase (lipoamide) beta
PDHX pyruvate dehydrogenase complex, component X
PDK1 pyruvate dehydrogenase kinase, isozyme 1
SGK1 serum/glucocorticoid regulated kinase 1
VSIG4 V-set and immunoglobulin domain containing 4