| Dataset | PhosphoSitePlus Substrates of Kinases |
| Category | physical interactions |
| Type | kinase |
| Description | pyruvate dehydrogenase kinase, isozyme 2|This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010] (NCBI Entrez Gene Database, 5164) |
| External Link | http://www.ncbi.nlm.nih.gov/gene/5164 |
| Similar Terms | |
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2 substrates of the kinase PDK2 from the curated PhosphoSitePlus Substrates of Kinases dataset.
