PDK2 Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description pyruvate dehydrogenase kinase, isozyme 2|This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010] (NCBI Entrez Gene Database, 5164)
External Link http://www.ncbi.nlm.nih.gov/gene/5164
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Genes

2 substrates of the kinase PDK2 from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2