PECAM1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description platelet/endothelial cell adhesion molecule 1|The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010] (NCBI Entrez Gene Database, 5175)
External Link https://ncbi.nlm.nih.gov/gene/5175
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Genes

499 genes differentially expressed following the PECAM1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
ADI1 acireductone dioxygenase 1 0.0188433
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0187908
CDCA4 cell division cycle associated 4 0.0164834
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.0138712
TXNDC9 thioredoxin domain containing 9 0.0124961
LGALS13 lectin, galactoside-binding, soluble, 13 0.0117138
JCHAIN joining chain of multimeric IgA and IgM 0.0116321
NUSAP1 nucleolar and spindle associated protein 1 0.0106509
S100A7 S100 calcium binding protein A7 0.0106327
BEX1 brain expressed, X-linked 1 0.0102982
NEFH neurofilament, heavy polypeptide 0.0102243
CSTA cystatin A (stefin A) 0.0102098
PBK PDZ binding kinase 0.0101621
SRGN serglycin 0.0101215
CASP1 caspase 1, apoptosis-related cysteine peptidase 0.00982208
WDR61 WD repeat domain 61 0.00953585
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.0093063
LGALS1 lectin, galactoside-binding, soluble, 1 0.00923701
DNASE1L3 deoxyribonuclease I-like 3 0.00922561
CXCL12 chemokine (C-X-C motif) ligand 12 0.00922404
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.00920756
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00920081
MMP12 matrix metallopeptidase 12 0.00917734
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 0.0090889
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.00904612
FGL2 fibrinogen-like 2 0.00892051
RPA3 replication protein A3, 14kDa 0.00890513
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.00890016
CYCS cytochrome c, somatic 0.00888016
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00883881
NEK2 NIMA-related kinase 2 0.00876847
C3ORF14 chromosome 3 open reading frame 14 0.00876631
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.00874375
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.00873271
YEATS4 YEATS domain containing 4 0.00870872
CXCL14 chemokine (C-X-C motif) ligand 14 0.00868877
EPHB2 EPH receptor B2 0.00863736
NVL nuclear VCP-like 0.00861731
OLFM4 olfactomedin 4 0.0085089
LGALS3 lectin, galactoside-binding, soluble, 3 0.00848783
TMEM38B transmembrane protein 38B 0.00847968
CDHR1 cadherin-related family member 1 0.00836346
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.00827051
CRYM crystallin, mu 0.00826381
VRK1 vaccinia related kinase 1 0.00826087
FERMT1 fermitin family member 1 0.00815294
TMEM45A transmembrane protein 45A 0.00813627
CALML5 calmodulin-like 5 0.00813348
GTPBP8 GTP-binding protein 8 (putative) 0.00811952
LEFTY1 left-right determination factor 1 0.00810238
MAP2K6 mitogen-activated protein kinase kinase 6 0.00809278
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00809246
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.00796591
KRT5 keratin 5, type II 0.00795298
TMPO thymopoietin 0.00791656
DIPK1A divergent protein kinase domain 1A 0.00790513
CD177 CD177 molecule 0.00788397
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 0.00786011
LTBP1 latent transforming growth factor beta binding protein 1 0.00782548
NUP107 nucleoporin 107kDa 0.00778259
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.00777305
LYZ lysozyme 0.00777203
STMN2 stathmin 2 0.00775098
CA2 carbonic anhydrase II 0.00767388
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 0.00765468
SIVA1 SIVA1, apoptosis-inducing factor 0.00763853
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.00762208
SUB1 SUB1 homolog (S. cerevisiae) 0.0075935
CD1E CD1e molecule 0.00759046
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 0.00758529
SNAP25 synaptosomal-associated protein, 25kDa 0.00757853
RXYLT1 ribitol xylosyltransferase 1 0.00756528
DCK deoxycytidine kinase 0.0075611
OIP5 Opa interacting protein 5 0.00751853
C12ORF29 chromosome 12 open reading frame 29 0.00750995
LTF lactotransferrin 0.00748567
XPO7 exportin 7 0.00747599
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 0.00747108
SDHAF3 succinate dehydrogenase complex assembly factor 3 0.00744163
KDM5D lysine (K)-specific demethylase 5D 0.0074329
CD8A CD8a molecule 0.00742148
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 0.00741113
CD48 CD48 molecule 0.00740301
PARM1 prostate androgen-regulated mucin-like protein 1 0.00739446
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit 0.0073773
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00737535
TMBIM4 transmembrane BAX inhibitor motif containing 4 0.00735861
IL7 interleukin 7 0.00734982
CCL5 chemokine (C-C motif) ligand 5 0.00733958
THBS1 thrombospondin 1 0.00729893
MARCKS myristoylated alanine-rich protein kinase C substrate 0.00727424
CCR2 chemokine (C-C motif) receptor 2 0.00725041
IL7R interleukin 7 receptor 0.0072439
RAB32 RAB32, member RAS oncogene family 0.00722423
NDRG2 NDRG family member 2 0.00722099
DIXDC1 DIX domain containing 1 0.00718852
EMP3 epithelial membrane protein 3 0.00717271
PRC1 protein regulator of cytokinesis 1 0.00716735
CNTNAP2 contactin associated protein-like 2 0.00714305
NT5DC2 5'-nucleotidase domain containing 2 0.00708412
LYN LYN proto-oncogene, Src family tyrosine kinase 0.00703976
LOR loricrin 0.00703965
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 0.00702958
RTN1 reticulon 1 0.00699446
FHOD3 formin homology 2 domain containing 3 0.00699383
NAE1 NEDD8 activating enzyme E1 subunit 1 0.0069879
COMMD8 COMM domain containing 8 0.00698141
AURKA aurora kinase A 0.0069785
NOX1 NADPH oxidase 1 0.00695161
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.00692715
JAG1 jagged 1 0.00691703
SDC1 syndecan 1 0.00685566
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.00685293
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00684718
WFDC1 WAP four-disulfide core domain 1 0.00683545
CCL19 chemokine (C-C motif) ligand 19 0.00682449
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 0.00680931
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00676581
BPHL biphenyl hydrolase-like (serine hydrolase) 0.00675991
PID1 phosphotyrosine interaction domain containing 1 0.00675699
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.00675688
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic 0.00674323
RNH1 ribonuclease/angiogenin inhibitor 1 0.00673817
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.00671266
UBE2N ubiquitin-conjugating enzyme E2N 0.00670341
PADI2 peptidyl arginine deiminase, type II 0.00669171
PTTG1 pituitary tumor-transforming 1 0.00668542
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.00667954
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 0.00666735
SPAG1 sperm associated antigen 1 0.00665441
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.00665071
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 0.006633
TTK TTK protein kinase 0.00662562
PIR pirin (iron-binding nuclear protein) 0.00661807
ADK adenosine kinase 0.00660116
BIRC5 baculoviral IAP repeat containing 5 0.00658562
CPVL carboxypeptidase, vitellogenic-like 0.00654685
CLCA1 chloride channel accessory 1 0.00653445
PRR7 proline rich 7 (synaptic) 0.00651741
ZG16 zymogen granule protein 16 0.00647834
RMI1 RecQ mediated genome instability 1 0.00647367
CLEC10A C-type lectin domain family 10, member A 0.00646779
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.00646494
CD2 CD2 molecule 0.00646376
LARS1 leucyl-tRNA synthetase 1 0.00645168
SPA17 sperm autoantigenic protein 17 0.00644245
CGRRF1 cell growth regulator with ring finger domain 1 0.00642735
SINHCAF SIN3-HDAC complex associated factor 0.00642402
RPP40 ribonuclease P/MRP 40kDa subunit 0.00642248
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 0.00641862
IL2RG interleukin 2 receptor, gamma 0.00641224
ACAT1 acetyl-CoA acetyltransferase 1 0.00639307
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.00637682
IGSF6 immunoglobulin superfamily, member 6 0.00636401
COL4A5 collagen, type IV, alpha 5 0.00635861
TGFBR3 transforming growth factor, beta receptor III 0.00635039
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.0063339
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1 0.00632971
TMEM168 transmembrane protein 168 0.00632964
DCXR dicarbonyl/L-xylulose reductase 0.00626527
RNASE3 ribonuclease, RNase A family, 3 0.00625962
SOAT1 sterol O-acyltransferase 1 0.0062583
ACTL6A actin-like 6A 0.00624902
CCNA2 cyclin A2 0.00624132
CCNE2 cyclin E2 0.00622731
LTB lymphotoxin beta (TNF superfamily, member 3) 0.00620827
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein 0.00616788
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.00616395
LST1 leukocyte specific transcript 1 0.00615435
PAK1IP1 PAK1 interacting protein 1 0.0061452
TMEM14B transmembrane protein 14B 0.00612741
FRZB frizzled-related protein 0.00612493
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 0.00612163
MELK maternal embryonic leucine zipper kinase 0.00611739
SOSTDC1 sclerostin domain containing 1 0.00611356
HMGB2 high mobility group box 2 0.00611245
NSL1 NSL1, MIS12 kinetochore complex component 0.00609111
PER3 period circadian clock 3 0.00607718
NIPSNAP2 nipsnap homolog 2 0.00606801
RFC3 replication factor C (activator 1) 3, 38kDa 0.00605503
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 0.00605018
GRB7 growth factor receptor-bound protein 7 0.00604066
PWP1 PWP1 homolog (S. cerevisiae) 0.00601865
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.00601297
SATB2 SATB homeobox 2 0.00599197
SORBS3 sorbin and SH3 domain containing 3 0.00598908
GZMK granzyme K (granzyme 3; tryptase II) 0.00598676
SPTSSA serine palmitoyltransferase, small subunit A 0.00596261
GATA6 GATA binding protein 6 0.00595386
PARPBP PARP1 binding protein 0.00594574
FMO5 flavin containing monooxygenase 5 0.00592705
KRT2 keratin 2, type II 0.00592179
NANS N-acetylneuraminic acid synthase 0.00589672
CD1C CD1c molecule 0.00589263
NQO1 NAD(P)H dehydrogenase, quinone 1 0.00588039
LMOD1 leiomodin 1 (smooth muscle) 0.00587859
CD9 CD9 molecule 0.00586853
LGALS2 lectin, galactoside-binding, soluble, 2 0.00585388
SLCO2A1 solute carrier organic anion transporter family, member 2A1 0.00583979
ELOVL6 ELOVL fatty acid elongase 6 0.00582268
PTGES prostaglandin E synthase 0.00581835
MAT2B methionine adenosyltransferase II, beta 0.00581403
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.00580198
CHEK2 checkpoint kinase 2 0.00579852
C1ORF174 chromosome 1 open reading frame 174 0.00579837
DMAC2L distal membrane arm assembly component 2 like 0.00579667
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 0.00579463
PSRC1 proline/serine-rich coiled-coil 1 0.00579205
CHMP4A charged multivesicular body protein 4A 0.00578246
HMGB3 high mobility group box 3 0.00576361
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.00574216
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00573992
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 0.00573218
PIGB phosphatidylinositol glycan anchor biosynthesis, class B 0.005732
DBF4 DBF4 zinc finger 0.00572982
FOXC1 forkhead box C1 0.00572681
NXPE4 neurexophilin and PC-esterase domain family, member 4 0.00571623
EPHX2 epoxide hydrolase 2, cytoplasmic 0.00570768
PDK1 pyruvate dehydrogenase kinase, isozyme 1 0.0057023
APOC2 apolipoprotein C-II 0.00569403
LY86 lymphocyte antigen 86 0.00569229
CLDN8 claudin 8 0.0056822
ITGA8 integrin, alpha 8 0.00568059
GUCY2C guanylate cyclase 2C 0.00567819
UBE2C ubiquitin-conjugating enzyme E2C 0.00567796
LXN latexin 0.00567021
KIF20B kinesin family member 20B 0.00566911
ACTR6 ARP6 actin-related protein 6 homolog (yeast) 0.00565616
COQ3 coenzyme Q3 methyltransferase 0.00562903
DSCC1 DNA replication and sister chromatid cohesion 1 0.0056164
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 0.00560098
CREBL2 cAMP responsive element binding protein-like 2 0.00559571
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 0.00558867
FAM162A family with sequence similarity 162, member A 0.00557782
PCP4 Purkinje cell protein 4 0.00556922
TDP1 tyrosyl-DNA phosphodiesterase 1 0.00556769
COPS4 COP9 signalosome subunit 4 0.00556383
TMX1 thioredoxin-related transmembrane protein 1 0.00555662
NCAPH non-SMC condensin I complex, subunit H 0.00555477
POLB polymerase (DNA directed), beta 0.00555334
BHMT betaine--homocysteine S-methyltransferase 0.00554828
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 0.00554029
SEPHS1 selenophosphate synthetase 1 0.00553185
DACH1 dachshund family transcription factor 1 0.00552976
TLK2 tousled-like kinase 2 0.00551496
SNX4 sorting nexin 4 0.00551122
CCP110 centriolar coiled coil protein 110kDa 0.00551101
MRPL33 mitochondrial ribosomal protein L33 0.00550127
NR1D2 nuclear receptor subfamily 1, group D, member 2 0.00549917
CAND1 cullin-associated and neddylation-dissociated 1 0.00548905

decreased expression

Symbol Name Standardized Value
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon -0.0179075
GNAS GNAS complex locus -0.016016
XIC X chromosome inactivation center -0.0146143
MAGEA3 melanoma antigen family A3 -0.0145253
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.0135198
ECM1 extracellular matrix protein 1 -0.0129792
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -0.012862
KLK10 kallikrein-related peptidase 10 -0.0117427
RGCC regulator of cell cycle -0.0116518
CD163 CD163 molecule -0.0110305
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.0110249
MYH10 myosin, heavy chain 10, non-muscle -0.0109615
HMOX1 heme oxygenase 1 -0.0109382
MTUS1 microtubule associated tumor suppressor 1 -0.010829
DOCK9 dedicator of cytokinesis 9 -0.0106545
FOXO1 forkhead box O1 -0.0105586
CEL carboxyl ester lipase -0.0105466
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.010416
ISG15 ISG15 ubiquitin-like modifier -0.0103601
ASPN asporin -0.010324
IFI6 interferon, alpha-inducible protein 6 -0.0101901
ACSL1 acyl-CoA synthetase long-chain family member 1 -0.0101873
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.0100597
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.0100594
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.0100216
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00990378
MAGEA12 melanoma antigen family A12 -0.00978549
PLK2 polo-like kinase 2 -0.00975121
ZMYM2 zinc finger, MYM-type 2 -0.00967826
AREG amphiregulin -0.00963948
LMO2 LIM domain only 2 (rhombotin-like 1) -0.00948717
PDZD2 PDZ domain containing 2 -0.00933927
MX1 MX dynamin-like GTPase 1 -0.00933577
GBP2 guanylate binding protein 2, interferon-inducible -0.00932443
CLDN7 claudin 7 -0.00931372
ABHD4 abhydrolase domain containing 4 -0.00930413
AKAP12 A kinase (PRKA) anchor protein 12 -0.00930281
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00930233
GARS1 glycyl-tRNA synthetase 1 -0.00928329
COL11A1 collagen, type XI, alpha 1 -0.00927161
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00923109
IL32 interleukin 32 -0.00922328
EGR1 early growth response 1 -0.00911464
THBS2 thrombospondin 2 -0.00908812
EGR2 early growth response 2 -0.00908034
SYT17 synaptotagmin XVII -0.00907142
VSIG4 V-set and immunoglobulin domain containing 4 -0.00904664
OLFML2B olfactomedin-like 2B -0.009021
DYNLL1 dynein, light chain, LC8-type 1 -0.00898032
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00897067
IER5 immediate early response 5 -0.00893434
DCHS1 dachsous cadherin-related 1 -0.00892876
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00891976
MFAP5 microfibrillar associated protein 5 -0.00891241
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00890688
COL5A2 collagen, type V, alpha 2 -0.00886248
IRS2 insulin receptor substrate 2 -0.00884732
TESC tescalcin -0.00882376
IFITM1 interferon induced transmembrane protein 1 -0.00868276
ITPKB inositol-trisphosphate 3-kinase B -0.00861607
LY96 lymphocyte antigen 96 -0.00853131
FABP4 fatty acid binding protein 4, adipocyte -0.00852799
GLUL glutamate-ammonia ligase -0.00849172
GIMAP6 GTPase, IMAP family member 6 -0.00841997
LTBP2 latent transforming growth factor beta binding protein 2 -0.00831343
HOPX HOP homeobox -0.00827498
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -0.00822898
NUPR1 nuclear protein, transcriptional regulator, 1 -0.00817668
ZMAT3 zinc finger, matrin-type 3 -0.00816189
KLK11 kallikrein-related peptidase 11 -0.00809859
LRRC17 leucine rich repeat containing 17 -0.00796242
THBS4 thrombospondin 4 -0.00789441
CDA cytidine deaminase -0.00784924
ZBED2 zinc finger, BED-type containing 2 -0.00784386
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00783642
NRN1 neuritin 1 -0.00776223
NEU1 sialidase 1 (lysosomal sialidase) -0.00772761
ANO1 anoctamin 1, calcium activated chloride channel -0.00772687
C5AR1 complement component 5a receptor 1 -0.00768427
CD14 CD14 molecule -0.00766975
OSBPL10 oxysterol binding protein-like 10 -0.00763528
IRF7 interferon regulatory factor 7 -0.00763383
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -0.00761951
ATF3 activating transcription factor 3 -0.00760844
OXA1L oxidase (cytochrome c) assembly 1-like -0.0075641
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) -0.00754466
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.00754248
PLXND1 plexin D1 -0.00753136
MEOX2 mesenchyme homeobox 2 -0.00751677
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.00747954
IFI44 interferon-induced protein 44 -0.00743847
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 -0.00743282
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 -0.00742509
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.00740125
ANKRD11 ankyrin repeat domain 11 -0.0073788
STC2 stanniocalcin 2 -0.00736555
GPRC5B G protein-coupled receptor, class C, group 5, member B -0.0073303
G0S2 G0/G1 switch 2 -0.00733
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -0.0072933
ZFP36 ZFP36 ring finger protein -0.00728589
FAM117A family with sequence similarity 117, member A -0.00725276
GABARAPL1 GABA(A) receptor-associated protein like 1 -0.00723509
ADGRG2 adhesion G protein-coupled receptor G2 -0.0072221
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 -0.00721288
TSPAN5 tetraspanin 5 -0.00719169
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.00718446
PLAAT3 phospholipase A and acyltransferase 3 -0.00717822
TSC22D2 TSC22 domain family, member 2 -0.00717633
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -0.00716784
TNNC1 troponin C type 1 (slow) -0.00715876
ABAT 4-aminobutyrate aminotransferase -0.00712905
MGLL monoglyceride lipase -0.00712446
CBS cystathionine-beta-synthase -0.00711448
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.00711091
WIPI1 WD repeat domain, phosphoinositide interacting 1 -0.00710091
JUP junction plakoglobin -0.00709467
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00708816
LAMA2 laminin, alpha 2 -0.00707005
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -0.00704862
CLEC2B C-type lectin domain family 2, member B -0.0070223
LAMB1 laminin, beta 1 -0.00701725
IL1B interleukin 1, beta -0.00698573
ABLIM1 actin binding LIM protein 1 -0.00697616
RFTN1 raftlin, lipid raft linker 1 -0.00695765
IDS iduronate 2-sulfatase -0.0069542
TBC1D16 TBC1 domain family, member 16 -0.0069521
TRIB3 tribbles pseudokinase 3 -0.00694052
CDH5 cadherin 5, type 2 (vascular endothelium) -0.00692153
IL1RN interleukin 1 receptor antagonist -0.00689773
SUSD6 sushi domain containing 6 -0.00688887
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -0.00686918
TPP1 tripeptidyl peptidase I -0.00686664
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) -0.00686108
KLHL24 kelch-like family member 24 -0.00684993
IFI27 interferon, alpha-inducible protein 27 -0.00684894
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00684098
PODXL podocalyxin-like -0.0068307
RRAGD Ras-related GTP binding D -0.00682464
EFNA1 ephrin-A1 -0.00682428
NPC1 Niemann-Pick disease, type C1 -0.00681801
PFN2 profilin 2 -0.00681456
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -0.00680094
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.0067978
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 -0.00679205
MCL1 myeloid cell leukemia 1 -0.00678732
H1-0 H1.0 linker histone -0.00677389
MMP2 matrix metallopeptidase 2 -0.0067634
CHP1 calcineurin-like EF-hand protein 1 -0.00676004
MIR22HG MIR22 host gene -0.00675551
FLT1 fms-related tyrosine kinase 1 -0.00675
IFI44L interferon-induced protein 44-like -0.00674898
PXDN peroxidasin -0.00674806
C8ORF4 chromosome 8 open reading frame 4 -0.00673762
KRT18 keratin 18, type I -0.00672484
RGS16 regulator of G-protein signaling 16 -0.00670267
AICDA activation-induced cytidine deaminase -0.00670233
PRAME preferentially expressed antigen in melanoma -0.00669474
TARS1 threonyl-tRNA synthetase 1 -0.00669381
SMAD3 SMAD family member 3 -0.00669097
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.00668918
ZFP36L1 ZFP36 ring finger protein-like 1 -0.00667793
SCG5 secretogranin V -0.0066585
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 -0.00665607
IFITM2 interferon induced transmembrane protein 2 -0.00665443
EIF5A eukaryotic translation initiation factor 5A -0.00665194
CTSL cathepsin L -0.0066503
CTSA cathepsin A -0.00664996
RSAD2 radical S-adenosyl methionine domain containing 2 -0.00662235
GPR137B G protein-coupled receptor 137B -0.00661929
GTPBP2 GTP binding protein 2 -0.00659383
KDR kinase insert domain receptor -0.00658461
ANGPT2 angiopoietin 2 -0.0065832
SIRT3 sirtuin 3 -0.0065536
DROSHA drosha, ribonuclease type III -0.00654942
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 -0.0065447
ZNF91 zinc finger protein 91 -0.00654223
ATP9A ATPase, class II, type 9A -0.00653802
RNF6 ring finger protein (C3H2C3 type) 6 -0.00653364
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 -0.00653086
HSPA1A heat shock 70kDa protein 1A -0.00651919
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00651791
ZNF83 zinc finger protein 83 -0.00650416
POU2AF1 POU class 2 associating factor 1 -0.00649208
ZSWIM8 zinc finger, SWIM-type containing 8 -0.00647036
VWF von Willebrand factor -0.0064652
FN1 fibronectin 1 -0.00645584
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.00645287
ATF4 activating transcription factor 4 -0.00644229
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -0.00642914
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 -0.00642156
ARG2 arginase 2 -0.0064205
CP ceruloplasmin (ferroxidase) -0.00640959
SULF1 sulfatase 1 -0.00640824
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.0063842
KLHL41 kelch-like family member 41 -0.00638241
FAM198B family with sequence similarity 198, member B -0.00638206
PLK3 polo-like kinase 3 -0.00637049
NOX4 NADPH oxidase 4 -0.00636907
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A -0.00634499
CPD carboxypeptidase D -0.00634004
RAB13 RAB13, member RAS oncogene family -0.00629853
FGG fibrinogen gamma chain -0.00629655
HOXA1 homeobox A1 -0.00628977
ADGRF5 adhesion G protein-coupled receptor F5 -0.00628842
CLDN10 claudin 10 -0.00627997
GPNMB glycoprotein (transmembrane) nmb -0.00627618
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -0.00626887
BRD2 bromodomain containing 2 -0.00625723
IGF2R insulin-like growth factor 2 receptor -0.00625479
MXRA5 matrix-remodelling associated 5 -0.00624638
MYC v-myc avian myelocytomatosis viral oncogene homolog -0.00622636
MSL1 male-specific lethal 1 homolog (Drosophila) -0.00622005
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -0.00619867
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 -0.0061897
ARID4B AT rich interactive domain 4B (RBP1-like) -0.00617918
ZBTB16 zinc finger and BTB domain containing 16 -0.00616847
ADAR adenosine deaminase, RNA-specific -0.00616296
ITSN2 intersectin 2 -0.00613547
JMJD1C jumonji domain containing 1C -0.00612907
TDO2 tryptophan 2,3-dioxygenase -0.00612207
FADS3 fatty acid desaturase 3 -0.00610497
PAM peptidylglycine alpha-amidating monooxygenase -0.00609525
INHBA inhibin, beta A -0.00609176
ORAI3 ORAI calcium release-activated calcium modulator 3 -0.00608945
ALOX5 arachidonate 5-lipoxygenase -0.00608447
MSX1 msh homeobox 1 -0.0060808
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.00606662
ELF1 E74-like factor 1 (ets domain transcription factor) -0.00605069
INHBE inhibin, beta E -0.00604119
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog -0.0060393
PCOLCE procollagen C-endopeptidase enhancer -0.00603861
SST somatostatin -0.0060175
IGLL1 immunoglobulin lambda-like polypeptide 1 -0.00600682
MMP10 matrix metallopeptidase 10 -0.00600638
TFF3 trefoil factor 3 (intestinal) -0.00599908
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 -0.00599126
BMERB1 bMERB domain containing 1 -0.0059887
WWC3 WWC family member 3 -0.00597894
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -0.0059653
CRCT1 cysteine-rich C-terminal 1 -0.00594374
GIMAP4 GTPase, IMAP family member 4 -0.00594339
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) -0.0059354
KIAA0100 KIAA0100 -0.00593075
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.00592471
AKAP8L A kinase (PRKA) anchor protein 8-like -0.00592103
SCNN1A sodium channel, non voltage gated 1 alpha subunit -0.00590743
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.00589835
ITM2A integral membrane protein 2A -0.00589765
CLCN4 chloride channel, voltage-sensitive 4 -0.00588816