PEX3 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description peroxisomal biogenesis factor 3|The product of this gene is involved in peroxisome biosynthesis and integrity. It assembles membrane vesicles before the matrix proteins are translocated. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause Zellweger syndrome (ZWS). [provided by RefSeq, Oct 2008] (NCBI Entrez Gene Database, 8504)
External Link http://www.ncbi.nlm.nih.gov/gene/8504
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Genes

63 interacting proteins for PEX3 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
AGPS alkylglycerone phosphate synthase
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATAD1 ATPase family, AAA domain containing 1
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4
CNOT1 CCR4-NOT transcription complex, subunit 1
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
DCTN1 dynactin 1
DHRS4 dehydrogenase/reductase (SDR family) member 4
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15
DNM1L dynamin 1-like
DNM2 dynamin 2
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
E2F1 E2F transcription factor 1
FAR1 fatty acyl CoA reductase 1
GNPAT glyceronephosphate O-acyltransferase
HNF4A hepatocyte nuclear factor 4, alpha
HNRNPF heterogeneous nuclear ribonucleoprotein F
HNRNPR heterogeneous nuclear ribonucleoprotein R
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
IQGAP1 IQ motif containing GTPase activating protein 1
IQGAP2 IQ motif containing GTPase activating protein 2
KIF11 kinesin family member 11
LRPPRC leucine-rich pentatricopeptide repeat containing
MAP2K2 mitogen-activated protein kinase kinase 2
MAX MYC associated factor X
MYC v-myc avian myelocytomatosis viral oncogene homolog
PEX1 peroxisomal biogenesis factor 1
PEX10 peroxisomal biogenesis factor 10
PEX13 peroxisomal biogenesis factor 13
PEX14 peroxisomal biogenesis factor 14
PEX16 peroxisomal biogenesis factor 16
PEX19 peroxisomal biogenesis factor 19
PEX2 peroxisomal biogenesis factor 2
PEX26 peroxisomal biogenesis factor 26
PEX5 peroxisomal biogenesis factor 5
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TCP1 t-complex 1
TCP11L1 t-complex 11, testis-specific-like 1
TTC1 tetratricopeptide repeat domain 1
TUBA1A tubulin, alpha 1a
TUBA1B tubulin, alpha 1b
TUBA4A tubulin, alpha 4a
TUBB tubulin, beta class I
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
TUBB3 tubulin, beta 3 class III
TUBB4A tubulin, beta 4A class IVa
TUBB4B tubulin, beta 4B class IVb
TUBB6 tubulin, beta 6 class V
TUBB8 tubulin, beta 8 class VIII
TUBG2 tubulin, gamma 2
UBC ubiquitin C