| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the PF-00539745-00-5939 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACACA | acetyl-CoA carboxylase alpha |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AEN | apoptosis enhancing nuclease |
| AGGF1 | angiogenic factor with G patch and FHA domains 1 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ALPK3 | alpha-kinase 3 |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| APOC1 | apolipoprotein C-I |
| APP | amyloid beta (A4) precursor protein |
| ARG2 | arginase 2 |
| ARL1 | ADP-ribosylation factor-like 1 |
| ARTN | artemin |
| ATN1 | atrophin 1 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 |
| ATXN7 | ataxin 7 |
| AURKA | aurora kinase A |
| BACH1 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 |
| BAIAP3 | BAI1-associated protein 3 |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| C17ORF53 | chromosome 17 open reading frame 53 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CDK18 | cyclin-dependent kinase 18 |
| CEP162 | centrosomal protein 162kDa |
| CEP68 | centrosomal protein 68kDa |
| CHML | choroideremia-like (Rab escort protein 2) |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CNTLN | centlein, centrosomal protein |
| CORT | cortistatin |
| CUL7 | cullin 7 |
| CYHR1 | cysteine/histidine-rich 1 |
| DAPK3 | death-associated protein kinase 3 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| EML3 | echinoderm microtubule associated protein like 3 |
| EPHB2 | EPH receptor B2 |
| EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit |
| FASTKD2 | FAST kinase domains 2 |
| FH | fumarate hydratase |
| FLT4 | fms-related tyrosine kinase 4 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| FYB | FYN binding protein |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFNA14 | interferon, alpha 14 |
| IFT27 | intraflagellar transport 27 |
| IL11 | interleukin 11 |
| IL36G | interleukin 36, gamma |
| ING4 | inhibitor of growth family, member 4 |
| ITPKA | inositol-trisphosphate 3-kinase A |
| KLF12 | Kruppel-like factor 12 |
| LIPG | lipase, endothelial |
| LMNB1 | lamin B1 |
| LOC644450 | uncharacterized LOC644450 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MANSC1 | MANSC domain containing 1 |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 |
| MXD4 | MAX dimerization protein 4 |
| NEUROG2 | neurogenin 2 |
| NOL12 | nucleolar protein 12 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PELO | pelota homolog (Drosophila) |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLXNB3 | plexin B3 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
| RGS14 | regulator of G-protein signaling 14 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| SAP18 | Sin3A-associated protein, 18kDa |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC35F6 | solute carrier family 35, member F6 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SOX30 | SRY (sex determining region Y)-box 30 |
| SPN | sialophorin |
| SREBF2 | sterol regulatory element binding transcription factor 2 |
| TK2 | thymidine kinase 2, mitochondrial |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TUBA3D | tubulin, alpha 3d |
| TUBD1 | tubulin, delta 1 |
| TXNL4A | thioredoxin-like 4A |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) |
| VWA1 | von Willebrand factor A domain containing 1 |
| WIZ | widely interspaced zinc finger motifs |
| WWOX | WW domain containing oxidoreductase |
| YTHDC2 | YTH domain containing 2 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF573 | zinc finger protein 573 |
| ZNF747 | zinc finger protein 747 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADAM3A | ADAM metallopeptidase domain 3A (pseudogene) |
| ADCK4 | aarF domain containing kinase 4 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ARG1 | arginase 1 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| ATP12A | ATPase, H+/K+ transporting, nongastric, alpha polypeptide |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C8A | complement component 8, alpha polypeptide |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CALB2 | calbindin 2 |
| CCT8L2 | chaperonin containing TCP1, subunit 8 (theta)-like 2 |
| CD70 | CD70 molecule |
| CEP85 | centrosomal protein 85kDa |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CLDND1 | claudin domain containing 1 |
| CLTCL1 | clathrin, heavy chain-like 1 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| ETNK2 | ethanolamine kinase 2 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FGF6 | fibroblast growth factor 6 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| GEMIN7 | gem (nuclear organelle) associated protein 7 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GMPR | guanosine monophosphate reductase |
| GPR85 | G protein-coupled receptor 85 |
| HIST1H3A | histone cluster 1, H3a |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| HOOK1 | hook microtubule-tethering protein 1 |
| HOXC13 | homeobox C13 |
| IL2 | interleukin 2 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 |
| KIAA0087 | KIAA0087 |
| KIAA0556 | KIAA0556 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LMTK2 | lemur tyrosine kinase 2 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| NBR2 | neighbor of BRCA1 gene 2 (non-protein coding) |
| NCS1 | neuronal calcium sensor 1 |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRDM12 | PR domain containing 12 |
| PROL1 | proline rich, lacrimal 1 |
| PRSS22 | protease, serine, 22 |
| PRSS53 | protease, serine, 53 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SELP | selectin P (granule membrane protein 140kDa, antigen CD62) |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
| SRD5A2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) |
| SSTR5 | somatostatin receptor 5 |
| SYNGR3 | synaptogyrin 3 |
| SYT13 | synaptotagmin XIII |
| TFCP2L1 | transcription factor CP2-like 1 |
| TFDP3 | transcription factor Dp family, member 3 |
| TMC7 | transmembrane channel-like 7 |
| TMEM180 | transmembrane protein 180 |
| TMEM19 | transmembrane protein 19 |
| TMEM209 | transmembrane protein 209 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TNS4 | tensin 4 |
| TPSD1 | tryptase delta 1 |
| TSC22D4 | TSC22 domain family, member 4 |
| TUBA4B | tubulin, alpha 4b |
| VGF | VGF nerve growth factor inducible |
| ZNF492 | zinc finger protein 492 |
| ZNF74 | zinc finger protein 74 |
| ZNF76 | zinc finger protein 76 |
