| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the PF-00539745-00-5974 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 |
| AMT | aminomethyltransferase |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| AR | androgen receptor |
| ATF6B | activating transcription factor 6 beta |
| BBS9 | Bardet-Biedl syndrome 9 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| CCDC9 | coiled-coil domain containing 9 |
| CCNO | cyclin O |
| CLIC2 | chloride intracellular channel 2 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| CTBS | chitobiase, di-N-acetyl- |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DUSP6 | dual specificity phosphatase 6 |
| EFNA3 | ephrin-A3 |
| EHD2 | EH-domain containing 2 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| EPOR | erythropoietin receptor |
| EXOSC2 | exosome component 2 |
| FAS | Fas cell surface death receptor |
| FRMD4A | FERM domain containing 4A |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AJ | histone cluster 1, H2aj |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HSPA12A | heat shock 70kDa protein 12A |
| ICAM1 | intercellular adhesion molecule 1 |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KIF1A | kinesin family member 1A |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LIN7B | lin-7 homolog B (C. elegans) |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LRRC14 | leucine rich repeat containing 14 |
| LRRC75B | leucine rich repeat containing 75B |
| LTB4R | leukotriene B4 receptor |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
| MARS | methionyl-tRNA synthetase |
| MEGF6 | multiple EGF-like-domains 6 |
| MIR622 | microRNA 622 |
| NCKAP1 | NCK-associated protein 1 |
| NDRG4 | NDRG family member 4 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NFX1 | nuclear transcription factor, X-box binding 1 |
| NMT1 | N-myristoyltransferase 1 |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NPRL3 | nitrogen permease regulator-like 3 (S. cerevisiae) |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NUP54 | nucleoporin 54kDa |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PAX5 | paired box 5 |
| PCDH1 | protocadherin 1 |
| PCGF3 | polycomb group ring finger 3 |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PITX1 | paired-like homeodomain 1 |
| PLIN2 | perilipin 2 |
| PML | promyelocytic leukemia |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| PRNP | prion protein |
| PRR5 | proline rich 5 (renal) |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| RAB27B | RAB27B, member RAS oncogene family |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RANBP3 | RAN binding protein 3 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
| S100A9 | S100 calcium binding protein A9 |
| SCAMP1 | secretory carrier membrane protein 1 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SIPA1 | signal-induced proliferation-associated 1 |
| SIRT3 | sirtuin 3 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 |
| SOCS6 | suppressor of cytokine signaling 6 |
| STS | steroid sulfatase (microsomal), isozyme S |
| STX3 | syntaxin 3 |
| TAZ | tafazzin |
| TCTN2 | tectonic family member 2 |
| TDRKH | tudor and KH domain containing |
| TFF2 | trefoil factor 2 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TPR | translocated promoter region, nuclear basket protein |
| TUBGCP3 | tubulin, gamma complex associated protein 3 |
| USP12 | ubiquitin specific peptidase 12 |
| VAMP5 | vesicle-associated membrane protein 5 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF573 | zinc finger protein 573 |
| ZNF586 | zinc finger protein 586 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ALDOAP2 | aldolase A, fructose-bisphosphate pseudogene 2 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ASIC4 | acid sensing (proton gated) ion channel family member 4 |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| BDNF | brain-derived neurotrophic factor |
| BICC1 | BicC family RNA binding protein 1 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CACNG3 | calcium channel, voltage-dependent, gamma subunit 3 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CD34 | CD34 molecule |
| CD8A | CD8a molecule |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLIP2 | CAP-GLY domain containing linker protein 2 |
| CNTN5 | contactin 5 |
| CORT | cortistatin |
| CPNE7 | copine VII |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CTRL | chymotrypsin-like |
| DUSP13 | dual specificity phosphatase 13 |
| EDAR | ectodysplasin A receptor |
| ELAVL2 | ELAV like neuron-specific RNA binding protein 2 |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| GAS2 | growth arrest-specific 2 |
| GFAP | glial fibrillary acidic protein |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GLRA1 | glycine receptor, alpha 1 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HAMP | hepcidin antimicrobial peptide |
| HCRTR2 | hypocretin (orexin) receptor 2 |
| HLA-DQB2 | major histocompatibility complex, class II, DQ beta 2 |
| HOXC8 | homeobox C8 |
| HPR | haptoglobin-related protein |
| INO80D | INO80 complex subunit D |
| ITM2C | integral membrane protein 2C |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KIAA0754 | KIAA0754 |
| KLHL25 | kelch-like family member 25 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 |
| LOC57399 | uncharacterized gastric protein ZA52P |
| LOC729164 | hCG1732469 |
| LRP4 | low density lipoprotein receptor-related protein 4 |
| LRRTM2 | leucine rich repeat transmembrane neuronal 2 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| OR10C1 | olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene) |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PCBP3 | poly(rC) binding protein 3 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PIDD1 | p53-induced death domain protein 1 |
| PLAC1 | placenta-specific 1 |
| POU3F2 | POU class 3 homeobox 2 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF2 | ring finger protein 2 |
| RORC | RAR-related orphan receptor C |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SECTM1 | secreted and transmembrane 1 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter), member 3 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SOCS7 | suppressor of cytokine signaling 7 |
| SPIDR | scaffolding protein involved in DNA repair |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SYNDIG1 | synapse differentiation inducing 1 |
| TEX40 | testis expressed 40 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMEM19 | transmembrane protein 19 |
| TMEM254 | transmembrane protein 254 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TRIM21 | tripartite motif containing 21 |
| TUBA3D | tubulin, alpha 3d |
| UCN | urocortin |
| ULBP2 | UL16 binding protein 2 |
| UNC13A | unc-13 homolog A (C. elegans) |
| VASH1 | vasohibin 1 |
| ZNF16 | zinc finger protein 16 |
| ZNF286A | zinc finger protein 286A |
| ZNF362 | zinc finger protein 362 |
| ZNF423 | zinc finger protein 423 |
| ZNF639 | zinc finger protein 639 |
| ZNF76 | zinc finger protein 76 |
