| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the PF-00539745-00-5979 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACVR1B | activin A receptor, type IB |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| AMBRA1 | autophagy/beclin-1 regulator 1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APOE | apolipoprotein E |
| ARL14 | ADP-ribosylation factor-like 14 |
| BRCA2 | breast cancer 2, early onset |
| BTBD18 | BTB (POZ) domain containing 18 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C1QL1 | complement component 1, q subcomponent-like 1 |
| C1S | complement component 1, s subcomponent |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CCDC71 | coiled-coil domain containing 71 |
| CD68 | CD68 molecule |
| CDK18 | cyclin-dependent kinase 18 |
| CEP295 | centrosomal protein 295kDa |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DOCK6 | dedicator of cytokinesis 6 |
| EDNRA | endothelin receptor type A |
| EFNA3 | ephrin-A3 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EMID1 | EMI domain containing 1 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM188A | family with sequence similarity 188, member A |
| FLT4 | fms-related tyrosine kinase 4 |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GGA3 | golgi-associated, gamma adaptin ear containing, ARF binding protein 3 |
| GK | glycerol kinase |
| GNAL | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type |
| GPR17 | G protein-coupled receptor 17 |
| GPR21 | G protein-coupled receptor 21 |
| HOMER3 | homer scaffolding protein 3 |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| IL17RA | interleukin 17 receptor A |
| IL17RB | interleukin 17 receptor B |
| IL33 | interleukin 33 |
| ING4 | inhibitor of growth family, member 4 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KIAA0319L | KIAA0319-like |
| KLF2 | Kruppel-like factor 2 |
| LIMD2 | LIM domain containing 2 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 |
| MAPK8IP2 | mitogen-activated protein kinase 8 interacting protein 2 |
| MECP2 | methyl CpG binding protein 2 |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NRP2 | neuropilin 2 |
| OR3A3 | olfactory receptor, family 3, subfamily A, member 3 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PALM | paralemmin |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDE10A | phosphodiesterase 10A |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PDIA2 | protein disulfide isomerase family A, member 2 |
| PENK | proenkephalin |
| PICK1 | protein interacting with PRKCA 1 |
| PLXND1 | plexin D1 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RANBP1 | RAN binding protein 1 |
| RECQL5 | RecQ protein-like 5 |
| RHOT2 | ras homolog family member T2 |
| RPL35A | ribosomal protein L35a |
| RUNDC3B | RUN domain containing 3B |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SFRP4 | secreted frizzled-related protein 4 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SH2D3A | SH2 domain containing 3A |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SQSTM1 | sequestosome 1 |
| STK4 | serine/threonine kinase 4 |
| STON1 | stonin 1 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMEM209 | transmembrane protein 209 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TREX1 | three prime repair exonuclease 1 |
| TRIM3 | tripartite motif containing 3 |
| TROVE2 | TROVE domain family, member 2 |
| YY1 | YY1 transcription factor |
| ZDHHC8P1 | zinc finger, DHHC-type containing 8 pseudogene 1 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF500 | zinc finger protein 500 |
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
| ACSBG2 | acyl-CoA synthetase bubblegum family member 2 |
| ADRA2B | adrenoceptor alpha 2B |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ANXA10 | annexin A10 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| ARMC4 | armadillo repeat containing 4 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| AUTS2 | autism susceptibility candidate 2 |
| BBC3 | BCL2 binding component 3 |
| BEND5 | BEN domain containing 5 |
| BMP15 | bone morphogenetic protein 15 |
| BNC1 | basonuclin 1 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C19ORF26 | chromosome 19 open reading frame 26 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CARD8 | caspase recruitment domain family, member 8 |
| CARF | calcium responsive transcription factor |
| CD82 | CD82 molecule |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| DEPDC5 | DEP domain containing 5 |
| DUSP8 | dual specificity phosphatase 8 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 |
| ETV6 | ets variant 6 |
| EVI2B | ecotropic viral integration site 2B |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FMOD | fibromodulin |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| HHIPL2 | HHIP-like 2 |
| HIST1H4C | histone cluster 1, H4c |
| HOXC5 | homeobox C5 |
| IGFBP1 | insulin-like growth factor binding protein 1 |
| INCENP | inner centromere protein antigens 135/155kDa |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNB1 | potassium channel, voltage gated Shab related subfamily B, member 1 |
| KLF15 | Kruppel-like factor 15 |
| KLHL29 | kelch-like family member 29 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| KRT86 | keratin 86, type II |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LYPD3 | LY6/PLAUR domain containing 3 |
| LYZL6 | lysozyme-like 6 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 |
| MLLT4-AS1 | MLLT4 antisense RNA 1 (head to head) |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MOXD1 | monooxygenase, DBH-like 1 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NAG18 | NAG18 mRNA |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
| OSMR | oncostatin M receptor |
| PARD6A | par-6 family cell polarity regulator alpha |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 |
| PCDH12 | protocadherin 12 |
| PLA1A | phospholipase A1 member A |
| PLCH2 | phospholipase C, eta 2 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| POLL | polymerase (DNA directed), lambda |
| PRDM12 | PR domain containing 12 |
| PRSS22 | protease, serine, 22 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| SAA4 | serum amyloid A4, constitutive |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SETD1A | SET domain containing 1A |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SMIM14 | small integral membrane protein 14 |
| SOSTDC1 | sclerostin domain containing 1 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| SYT13 | synaptotagmin XIII |
| TAS2R1 | taste receptor, type 2, member 1 |
| TCTN2 | tectonic family member 2 |
| THSD4 | thrombospondin, type I, domain containing 4 |
| TMEM144 | transmembrane protein 144 |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TNNT2 | troponin T type 2 (cardiac) |
| TRAF2 | TNF receptor-associated factor 2 |
| TRIM25 | tripartite motif containing 25 |
| TUBA4B | tubulin, alpha 4b |
| VGLL3 | vestigial-like family member 3 |
| XYLT1 | xylosyltransferase I |
| ZNF234 | zinc finger protein 234 |
| ZNF446 | zinc finger protein 446 |
| ZNF76 | zinc finger protein 76 |
| ZXDB | zinc finger, X-linked, duplicated B |
