| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the PF-00539758-00-6379 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ANGPTL4 | angiopoietin-like 4 |
| APAF1 | apoptotic peptidase activating factor 1 |
| APOE | apolipoprotein E |
| ARID1A | AT rich interactive domain 1A (SWI-like) |
| ARTN | artemin |
| ATN1 | atrophin 1 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| BCAN | brevican |
| C10ORF10 | chromosome 10 open reading frame 10 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CACYBP | calcyclin binding protein |
| CADM4 | cell adhesion molecule 4 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CARD14 | caspase recruitment domain family, member 14 |
| CAV2 | caveolin 2 |
| CBS | cystathionine-beta-synthase |
| CCNK | cyclin K |
| CD22 | CD22 molecule |
| CD6 | CD6 molecule |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CIC | capicua transcriptional repressor |
| COL1A1 | collagen, type I, alpha 1 |
| CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 |
| DTNB | dystrobrevin, beta |
| EMP1 | epithelial membrane protein 1 |
| EPX | eosinophil peroxidase |
| ESR1 | estrogen receptor 1 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| EWSR1 | EWS RNA-binding protein 1 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSL2 | FOS-like antigen 2 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GGT1 | gamma-glutamyltransferase 1 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR161 | G protein-coupled receptor 161 |
| GPR182 | G protein-coupled receptor 182 |
| HNF4A | hepatocyte nuclear factor 4, alpha |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 |
| IFFO1 | intermediate filament family orphan 1 |
| IFT122 | intraflagellar transport 122 |
| IGFLR1 | IGF-like family receptor 1 |
| IRF4 | interferon regulatory factor 4 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KIAA1109 | KIAA1109 |
| KLHL12 | kelch-like family member 12 |
| LAMC3 | laminin, gamma 3 |
| LIPE | lipase, hormone-sensitive |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAP7D3 | MAP7 domain containing 3 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MLXIPL | MLX interacting protein-like |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NCOR2 | nuclear receptor corepressor 2 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NPFFR1 | neuropeptide FF receptor 1 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDCD2 | programmed cell death 2 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PGLYRP4 | peptidoglycan recognition protein 4 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLA2G1B | phospholipase A2, group IB (pancreas) |
| PLK3 | polo-like kinase 3 |
| POU5F1B | POU class 5 homeobox 1B |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PRTN3 | proteinase 3 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RPL23AP53 | ribosomal protein L23a pseudogene 53 |
| SAA4 | serum amyloid A4, constitutive |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SCNN1B | sodium channel, non voltage gated 1 beta subunit |
| SHOX2 | short stature homeobox 2 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SRPK2 | SRSF protein kinase 2 |
| STAC | SH3 and cysteine rich domain |
| TBC1D2B | TBC1 domain family, member 2B |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TLE4 | transducin-like enhancer of split 4 |
| TLN2 | talin 2 |
| TMEM74B | transmembrane protein 74B |
| TNS1 | tensin 1 |
| TRIM25 | tripartite motif containing 25 |
| TRIM3 | tripartite motif containing 3 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| UBXN1 | UBX domain protein 1 |
| VCL | vinculin |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| Symbol | Name |
|---|---|
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BNC1 | basonuclin 1 |
| CBLC | Cbl proto-oncogene C, E3 ubiquitin protein ligase |
| CCR9 | chemokine (C-C motif) receptor 9 |
| CDK6 | cyclin-dependent kinase 6 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CLEC7A | C-type lectin domain family 7, member A |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| CNTLN | centlein, centrosomal protein |
| COL21A1 | collagen, type XXI, alpha 1 |
| COL9A2 | collagen, type IX, alpha 2 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CPLX2 | complexin 2 |
| CPNE7 | copine VII |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| CYP39A1 | cytochrome P450, family 39, subfamily A, polypeptide 1 |
| DDN | dendrin |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| DSCAM | Down syndrome cell adhesion molecule |
| DUSP2 | dual specificity phosphatase 2 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FLJ11710 | uncharacterized protein FLJ11710 |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GOLGA2P5 | golgin A2 pseudogene 5 |
| GPR27 | G protein-coupled receptor 27 |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| GRM4 | glutamate receptor, metabotropic 4 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HIST1H2AK | histone cluster 1, H2ak |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| IFNW1 | interferon, omega 1 |
| INE1 | inactivation escape 1 (non-protein coding) |
| IREB2 | iron-responsive element binding protein 2 |
| IRF8 | interferon regulatory factor 8 |
| KCNB1 | potassium channel, voltage gated Shab related subfamily B, member 1 |
| KEL | Kell blood group, metallo-endopeptidase |
| KIFC3 | kinesin family member C3 |
| LEFTY1 | left-right determination factor 1 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LIPF | lipase, gastric |
| LMTK2 | lemur tyrosine kinase 2 |
| MEGF8 | multiple EGF-like-domains 8 |
| MIP | major intrinsic protein of lens fiber |
| NECAB2 | N-terminal EF-hand calcium binding protein 2 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NPY4R | neuropeptide Y receptor Y4 |
| NXF2 | nuclear RNA export factor 2 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OTOR | otoraplin |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PER3 | period circadian clock 3 |
| PICK1 | protein interacting with PRKCA 1 |
| POLL | polymerase (DNA directed), lambda |
| POPDC2 | popeye domain containing 2 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RAB36 | RAB36, member RAS oncogene family |
| RAB3D | RAB3D, member RAS oncogene family |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RIMS1 | regulating synaptic membrane exocytosis 1 |
| RLN1 | relaxin 1 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| RNF208 | ring finger protein 208 |
| RYR1 | ryanodine receptor 1 (skeletal) |
| S1PR1 | sphingosine-1-phosphate receptor 1 |
| SCAI | suppressor of cancer cell invasion |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SLC2A11 | solute carrier family 2 (facilitated glucose transporter), member 11 |
| SLC9A7 | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 |
| STMN3 | stathmin-like 3 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMEM209 | transmembrane protein 209 |
| TOR3A | torsin family 3, member A |
| TTC21B | tetratricopeptide repeat domain 21B |
| TUBB2B | tubulin, beta 2B class IIb |
| VNN1 | vanin 1 |
| VPS9D1 | VPS9 domain containing 1 |
| XDH | xanthine dehydrogenase |
| ZNF219 | zinc finger protein 219 |
| ZNF230 | zinc finger protein 230 |
| ZNF391 | zinc finger protein 391 |
| ZNF671 | zinc finger protein 671 |
| ZNF76 | zinc finger protein 76 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
