| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the PF-00539758-00-6421 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD6 | abhydrolase domain containing 6 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| ADRA1D | adrenoceptor alpha 1D |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ANKRD26 | ankyrin repeat domain 26 |
| APOL2 | apolipoprotein L, 2 |
| ARIH2 | ariadne RBR E3 ubiquitin protein ligase 2 |
| BBS7 | Bardet-Biedl syndrome 7 |
| BSPRY | B-box and SPRY domain containing |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CCDC101 | coiled-coil domain containing 101 |
| CCNG2 | cyclin G2 |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| COL6A1 | collagen, type VI, alpha 1 |
| COX15 | cytochrome c oxidase assembly homolog 15 (yeast) |
| CPT1A | carnitine palmitoyltransferase 1A (liver) |
| CTTN | cortactin |
| EN1 | engrailed homeobox 1 |
| EVC | Ellis van Creveld protein |
| FBLN1 | fibulin 1 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FLCN | folliculin |
| FN1 | fibronectin 1 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 |
| GLCE | glucuronic acid epimerase |
| GLUL | glutamate-ammonia ligase |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GOSR2 | golgi SNAP receptor complex member 2 |
| GRB7 | growth factor receptor-bound protein 7 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| HIST1H2AG | histone cluster 1, H2ag |
| HOMER3 | homer scaffolding protein 3 |
| HSF1 | heat shock transcription factor 1 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| IQCE | IQ motif containing E |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KDM5A | lysine (K)-specific demethylase 5A |
| KIAA1549L | KIAA1549-like |
| KIF16B | kinesin family member 16B |
| KLHL20 | kelch-like family member 20 |
| MAP2K3 | mitogen-activated protein kinase kinase 3 |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 |
| MCMBP | minichromosome maintenance complex binding protein |
| MPPE1 | metallophosphoesterase 1 |
| MTMR1 | myotubularin related protein 1 |
| MTUS1 | microtubule associated tumor suppressor 1 |
| MXD3 | MAX dimerization protein 3 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| N4BP1 | NEDD4 binding protein 1 |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NDE1 | nudE neurodevelopment protein 1 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OSMR | oncostatin M receptor |
| PARVB | parvin, beta |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PER1 | period circadian clock 1 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PFDN6 | prefoldin subunit 6 |
| PLCD1 | phospholipase C, delta 1 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRR4 | proline rich 4 (lacrimal) |
| RANBP1 | RAN binding protein 1 |
| RECQL5 | RecQ protein-like 5 |
| RPL10 | ribosomal protein L10 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SAPCD1 | suppressor APC domain containing 1 |
| SHB | Src homology 2 domain containing adaptor protein B |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
| STC1 | stanniocalcin 1 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SYT1 | synaptotagmin I |
| TBCD | tubulin folding cofactor D |
| TK2 | thymidine kinase 2, mitochondrial |
| TLN1 | talin 1 |
| TMEM259 | transmembrane protein 259 |
| TUBA3C | tubulin, alpha 3c |
| USF2 | upstream transcription factor 2, c-fos interacting |
| WBP2 | WW domain binding protein 2 |
| ZBTB1 | zinc finger and BTB domain containing 1 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF10 | zinc finger protein 10 |
| ZNF701 | zinc finger protein 701 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| AHSP | alpha hemoglobin stabilizing protein |
| ALPK1 | alpha-kinase 1 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| C11ORF21 | chromosome 11 open reading frame 21 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C3AR1 | complement component 3a receptor 1 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CDK3 | cyclin-dependent kinase 3 |
| CFD | complement factor D (adipsin) |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CREB5 | cAMP responsive element binding protein 5 |
| DDN | dendrin |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| FAM50B | family with sequence similarity 50, member B |
| FANCC | Fanconi anemia, complementation group C |
| FLT4 | fms-related tyrosine kinase 4 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GAS2 | growth arrest-specific 2 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GLDC | glycine dehydrogenase (decarboxylating) |
| HIST1H2BJ | histone cluster 1, H2bj |
| HMOX1 | heme oxygenase 1 |
| HOXA6 | homeobox A6 |
| HSF2BP | heat shock transcription factor 2 binding protein |
| KCNB1 | potassium channel, voltage gated Shab related subfamily B, member 1 |
| KRT8P12 | keratin 8 pseudogene 12 |
| LGALS9 | lectin, galactoside-binding, soluble, 9 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LOC729164 | hCG1732469 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| MCC | mutated in colorectal cancers |
| MED31 | mediator complex subunit 31 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MFI2 | antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 |
| MMP10 | matrix metallopeptidase 10 |
| MMP2 | matrix metallopeptidase 2 |
| MON1B | MON1 secretory trafficking family member B |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NELL2 | NEL-like 2 (chicken) |
| NOL10 | nucleolar protein 10 |
| NOL12 | nucleolar protein 12 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NPHP1 | nephronophthisis 1 (juvenile) |
| NTF3 | neurotrophin 3 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| ODF1 | outer dense fiber of sperm tails 1 |
| OLFML2A | olfactomedin-like 2A |
| OSBP2 | oxysterol binding protein 2 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PODNL1 | podocan-like 1 |
| PODXL2 | podocalyxin-like 2 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RETN | resistin |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCNN1B | sodium channel, non voltage gated 1 beta subunit |
| SDC3 | syndecan 3 |
| SERPINI2 | serpin peptidase inhibitor, clade I (pancpin), member 2 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SIX3 | SIX homeobox 3 |
| SMCP | sperm mitochondria-associated cysteine-rich protein |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TMEM212 | transmembrane protein 212 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRIM25 | tripartite motif containing 25 |
| TRIM45 | tripartite motif containing 45 |
| TTC30A | tetratricopeptide repeat domain 30A |
| TUBB2B | tubulin, beta 2B class IIb |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VASP | vasodilator-stimulated phosphoprotein |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR78 | WD repeat domain 78 |
| WFDC2 | WAP four-disulfide core domain 2 |
| YOD1 | YOD1 deubiquitinase |
| ZNF155 | zinc finger protein 155 |
| ZNF214 | zinc finger protein 214 |
| ZNF253 | zinc finger protein 253 |
| ZNF276 | zinc finger protein 276 |
| ZNF671 | zinc finger protein 671 |
| ZNF76 | zinc finger protein 76 |
