PF-00562151-00-5922 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the PF-00562151-00-5922 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADGRB2 adhesion G protein-coupled receptor B2
AIM1L absent in melanoma 1-like
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
APOLD1 apolipoprotein L domain containing 1
APOM apolipoprotein M
ARNT aryl hydrocarbon receptor nuclear translocator
BCL6 B-cell CLL/lymphoma 6
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C10ORF10 chromosome 10 open reading frame 10
C1ORF56 chromosome 1 open reading frame 56
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CCDC106 coiled-coil domain containing 106
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD34 CD34 molecule
CDC14A cell division cycle 14A
CDK10 cyclin-dependent kinase 10
CDK18 cyclin-dependent kinase 18
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CIDEB cell death-inducing DFFA-like effector b
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CNTNAP2 contactin associated protein-like 2
CXORF56 chromosome X open reading frame 56
DGKA diacylglycerol kinase, alpha 80kDa
DRD2 dopamine receptor D2
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
EVI5 ecotropic viral integration site 5
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit
FAM131B family with sequence similarity 131, member B
FBXO22 F-box protein 22
FBXO31 F-box protein 31
FGFR1 fibroblast growth factor receptor 1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GALK1 galactokinase 1
GNAS GNAS complex locus
GPER1 G protein-coupled estrogen receptor 1
GPR4 G protein-coupled receptor 4
GRIK2 glutamate receptor, ionotropic, kainate 2
GSTCD glutathione S-transferase, C-terminal domain containing
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HEG1 heart development protein with EGF-like domains 1
HIC2 hypermethylated in cancer 2
HIST1H2BO histone cluster 1, H2bo
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HPS1 Hermansky-Pudlak syndrome 1
INPP5J inositol polyphosphate-5-phosphatase J
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KRT17 keratin 17, type I
LRRK1 leucine-rich repeat kinase 1
MAGEF1 melanoma antigen family F1
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MRPS18C mitochondrial ribosomal protein S18C
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYO9B myosin IXB
NACAD NAC alpha domain containing
NCOA2 nuclear receptor coactivator 2
NCOR2 nuclear receptor corepressor 2
NEBL nebulette
NFYA nuclear transcription factor Y, alpha
NOVA1 neuro-oncological ventral antigen 1
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NR4A1 nuclear receptor subfamily 4, group A, member 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE4DIP phosphodiesterase 4D interacting protein
PRAF2 PRA1 domain family, member 2
PRB3 proline-rich protein BstNI subfamily 3
RABGAP1L RAB GTPase activating protein 1-like
RPL23AP32 ribosomal protein L23a pseudogene 32
RPLP2 ribosomal protein, large, P2
RS1 retinoschisin 1
RUNX1 runt-related transcription factor 1
SCN9A sodium channel, voltage gated, type IX alpha subunit
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SOGA1 suppressor of glucose, autophagy associated 1
SPATA6 spermatogenesis associated 6
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
STAG3 stromal antigen 3
STOML1 stomatin (EPB72)-like 1
TFEB transcription factor EB
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TINAGL1 tubulointerstitial nephritis antigen-like 1
TLX2 T-cell leukemia homeobox 2
TMEM53 transmembrane protein 53
TOM1 target of myb1 (chicken)
TRIM14 tripartite motif containing 14
TRIO trio Rho guanine nucleotide exchange factor
TTC22 tetratricopeptide repeat domain 22
TTC30A tetratricopeptide repeat domain 30A
TTLL3 tubulin tyrosine ligase-like family member 3
ULK2 unc-51 like autophagy activating kinase 2
UNC45A unc-45 homolog A (C. elegans)
WFDC2 WAP four-disulfide core domain 2
ZNF76 zinc finger protein 76
ZNF767P zinc finger family member 767, pseudogene

decreased expression

Symbol Name
ADAM23 ADAM metallopeptidase domain 23
AGBL3 ATP/GTP binding protein-like 3
AMDHD2 amidohydrolase domain containing 2
ANKRD55 ankyrin repeat domain 55
ANKRD7 ankyrin repeat domain 7
APH1B APH1B gamma secretase subunit
ARID5A AT rich interactive domain 5A (MRF1-like)
ASAP1-IT1 ASAP1 intronic transcript 1
ASTN1 astrotactin 1
ATG10 autophagy related 10
BAAT bile acid CoA:amino acid N-acyltransferase
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
BTF3P12 basic transcription factor 3 pseudogene 12
C17ORF80 chromosome 17 open reading frame 80
C22ORF46 chromosome 22 open reading frame 46
C8ORF44 chromosome 8 open reading frame 44
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CAMKMT calmodulin-lysine N-methyltransferase
CATR1 CATR tumorigenicity conversion 1
CD82 CD82 molecule
CENPJ centromere protein J
CEP295 centrosomal protein 295kDa
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRLF1 cytokine receptor-like factor 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DES desmin
DOCK3 dedicator of cytokinesis 3
ENOX1 ecto-NOX disulfide-thiol exchanger 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EXO5 exonuclease 5
FLJ20712 uncharacterized FLJ20712
GJA8 gap junction protein, alpha 8, 50kDa
GPR19 G protein-coupled receptor 19
HSF2BP heat shock transcription factor 2 binding protein
IL17RB interleukin 17 receptor B
IL32 interleukin 32
IQSEC2 IQ motif and Sec7 domain 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KERA keratocan
KIAA1456 KIAA1456
KL klotho
LEFTY1 left-right determination factor 1
LIME1 Lck interacting transmembrane adaptor 1
LMNB1 lamin B1
LOC257152 uncharacterized LOC257152
MAGEA10 melanoma antigen family A10
MAGOH2P mago-nashi homolog 2, pseudogene
MED31 mediator complex subunit 31
MEGF8 multiple EGF-like-domains 8
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MYOZ3 myozenin 3
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NOL6 nucleolar protein 6 (RNA-associated)
NPIPB15 nuclear pore complex interacting protein family, member B15
NPM3 nucleophosmin/nucleoplasmin 3
NR3C2 nuclear receptor subfamily 3, group C, member 2
ODF2 outer dense fiber of sperm tails 2
OXCT2 3-oxoacid CoA transferase 2
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PALM paralemmin
PEX26 peroxisomal biogenesis factor 26
PF4V1 platelet factor 4 variant 1
PMCH pro-melanin-concentrating hormone
PNPLA3 patatin-like phospholipase domain containing 3
PRF1 perforin 1 (pore forming protein)
PTCH2 patched 2
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAVER2 ribonucleoprotein, PTB-binding 2
RPL23AP53 ribosomal protein L23a pseudogene 53
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
S100B S100 calcium binding protein B
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SELL selectin L
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SETD8 SET domain containing (lysine methyltransferase) 8
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SPTBN5 spectrin, beta, non-erythrocytic 5
STK32B serine/threonine kinase 32B
STXBP5L syntaxin binding protein 5-like
TADA2A transcriptional adaptor 2A
TCP10L t-complex 10-like
TCP11 t-complex 11, testis-specific
TEC tec protein tyrosine kinase
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TNN tenascin N
TRAC T cell receptor alpha constant
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF254 zinc finger protein 254
ZNF428 zinc finger protein 428
ZNF480 zinc finger protein 480
ZNF516 zinc finger protein 516
ZNF667 zinc finger protein 667
ZNF702P zinc finger protein 702, pseudogene
ZNF749 zinc finger protein 749