PF-00562151-00-6863 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the PF-00562151-00-6863 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACAD10 acyl-CoA dehydrogenase family, member 10
ADGRB2 adhesion G protein-coupled receptor B2
ALAD aminolevulinate dehydratase
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
APOL6 apolipoprotein L, 6
BCAM basal cell adhesion molecule (Lutheran blood group)
BCL2L1 BCL2-like 1
BICD1 bicaudal D homolog 1 (Drosophila)
BTG2 BTG family, member 2
C11ORF63 chromosome 11 open reading frame 63
C17ORF59 chromosome 17 open reading frame 59
CA9 carbonic anhydrase IX
CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase
CDC14A cell division cycle 14A
CDC40 cell division cycle 40
CDK3 cyclin-dependent kinase 3
CEP68 centrosomal protein 68kDa
CISH cytokine inducible SH2-containing protein
CLN5 ceroid-lipofuscinosis, neuronal 5
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
E2F4 E2F transcription factor 4, p107/p130-binding
ERAP2 endoplasmic reticulum aminopeptidase 2
FAM53B family with sequence similarity 53, member B
FBXO38 F-box protein 38
FGF18 fibroblast growth factor 18
FGFR1 fibroblast growth factor receptor 1
FHL1 four and a half LIM domains 1
FOXG1 forkhead box G1
FZD7 frizzled class receptor 7
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GPATCH2L G patch domain containing 2-like
GPR3 G protein-coupled receptor 3
HDAC5 histone deacetylase 5
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IGF1R insulin-like growth factor 1 receptor
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IL15RA interleukin 15 receptor, alpha
IL20RA interleukin 20 receptor, alpha
IL23A interleukin 23, alpha subunit p19
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
ITCH itchy E3 ubiquitin protein ligase
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
LIPE lipase, hormone-sensitive
LMF1 lipase maturation factor 1
LPAR6 lysophosphatidic acid receptor 6
LRP6 low density lipoprotein receptor-related protein 6
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAPK7 mitogen-activated protein kinase 7
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MBTPS1 membrane-bound transcription factor peptidase, site 1
MED18 mediator complex subunit 18
MFGE8 milk fat globule-EGF factor 8 protein
MMP13 matrix metallopeptidase 13
MOB3B MOB kinase activator 3B
MTA1 metastasis associated 1
NARFL nuclear prelamin A recognition factor-like
NFX1 nuclear transcription factor, X-box binding 1
NPEPL1 aminopeptidase-like 1
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OGFR opioid growth factor receptor
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PEX26 peroxisomal biogenesis factor 26
PKP3 plakophilin 3
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRICKLE3 prickle homolog 3 (Drosophila)
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRR5 proline rich 5 (renal)
PTK2B protein tyrosine kinase 2 beta
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RBM48 RNA binding motif protein 48
RCAN3 RCAN family member 3
RDX radixin
SARM1 sterile alpha and TIR motif containing 1
SBF1 SET binding factor 1
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SH2B1 SH2B adaptor protein 1
SPINK5 serine peptidase inhibitor, Kazal type 5
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAGLN3 transgelin 3
TDRD3 tudor domain containing 3
TFDP1 transcription factor Dp-1
TMEM209 transmembrane protein 209
TMOD3 tropomodulin 3 (ubiquitous)
TUBA3C tubulin, alpha 3c
ZNF174 zinc finger protein 174
ZNF37BP zinc finger protein 37B, pseudogene
ZNF552 zinc finger protein 552

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ACKR3 atypical chemokine receptor 3
ACOT8 acyl-CoA thioesterase 8
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
ADAP2 ArfGAP with dual PH domains 2
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ATAD5 ATPase family, AAA domain containing 5
ATP4B ATPase, H+/K+ exchanging, beta polypeptide
ATXN2 ataxin 2
AVPR1B arginine vasopressin receptor 1B
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
C16ORF59 chromosome 16 open reading frame 59
C1ORF95 chromosome 1 open reading frame 95
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C8B complement component 8, beta polypeptide
CAPN15 calpain 15
CCNE1 cyclin E1
CD300C CD300c molecule
CDK20 cyclin-dependent kinase 20
CEP295 centrosomal protein 295kDa
CFAP44 cilia and flagella associated protein 44
CNPY4 canopy FGF signaling regulator 4
CTF1 cardiotrophin 1
CTRC chymotrypsin C (caldecrin)
CTSK cathepsin K
CXORF21 chromosome X open reading frame 21
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DNMBP dynamin binding protein
DPH2 DPH2 homolog (S. cerevisiae)
ESRP2 epithelial splicing regulatory protein 2
FAM120C family with sequence similarity 120C
FAM186A family with sequence similarity 186, member A
FGL1 fibrinogen-like 1
FOXC1 forkhead box C1
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GUCA1B guanylate cyclase activator 1B (retina)
HIST1H1D histone cluster 1, H1d
HOXC11 homeobox C11
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
KIAA1324 KIAA1324
KIF13A kinesin family member 13A
KLHL25 kelch-like family member 25
KLK1 kallikrein 1
KRT4 keratin 4, type II
LINC00260 long intergenic non-protein coding RNA 260
LMNB1 lamin B1
LY6G5C lymphocyte antigen 6 complex, locus G5C
MEOX1 mesenchyme homeobox 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MYLK myosin light chain kinase
NEK11 NIMA-related kinase 11
NKX3-2 NK3 homeobox 2
OSGIN1 oxidative stress induced growth inhibitor 1
OSMR oncostatin M receptor
PALM paralemmin
PAQR5 progestin and adipoQ receptor family member V
PHOX2B paired-like homeobox 2b
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PNPLA3 patatin-like phospholipase domain containing 3
POMT2 protein-O-mannosyltransferase 2
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RASAL2 RAS protein activator like 2
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RORC RAR-related orphan receptor C
RWDD2A RWD domain containing 2A
S100A3 S100 calcium binding protein A3
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SETD1A SET domain containing 1A
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SPINK1 serine peptidase inhibitor, Kazal type 1
SPTBN2 spectrin, beta, non-erythrocytic 2
SYT17 synaptotagmin XVII
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAGLN transgelin
TESPA1 thymocyte expressed, positive selection associated 1
TM4SF5 transmembrane 4 L six family member 5
TMEM212 transmembrane protein 212
TMPRSS6 transmembrane protease, serine 6
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TTLL7 tubulin tyrosine ligase-like family member 7
WDR4 WD repeat domain 4
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZFP69B ZFP69 zinc finger protein B
ZNF205 zinc finger protein 205
ZNF219 zinc finger protein 219
ZNF665 zinc finger protein 665
ZNF747 zinc finger protein 747