| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the PF-00562151-00-6912 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AASDHPPT | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ABHD3 | abhydrolase domain containing 3 |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type |
| ADAM9 | ADAM metallopeptidase domain 9 |
| ADK | adenosine kinase |
| AREG | amphiregulin |
| ASPH | aspartate beta-hydroxylase |
| ATM | ATM serine/threonine kinase |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| C17ORF75 | chromosome 17 open reading frame 75 |
| C1ORF109 | chromosome 1 open reading frame 109 |
| CBR4 | carbonyl reductase 4 |
| CD302 | CD302 molecule |
| CDK8 | cyclin-dependent kinase 8 |
| CEP72 | centrosomal protein 72kDa |
| CRY1 | cryptochrome circadian clock 1 |
| DOCK9 | dedicator of cytokinesis 9 |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| EIF4E | eukaryotic translation initiation factor 4E |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FAIM | Fas apoptotic inhibitory molecule |
| GAN | gigaxonin |
| GCA | grancalcin, EF-hand calcium binding protein |
| GINS3 | GINS complex subunit 3 (Psf3 homolog) |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GLRX | glutaredoxin (thioltransferase) |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| HABP4 | hyaluronan binding protein 4 |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IL1RAP | interleukin 1 receptor accessory protein |
| IRF2 | interferon regulatory factor 2 |
| ITGA6 | integrin, alpha 6 |
| ITGB5 | integrin, beta 5 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| JMJD1C | jumonji domain containing 1C |
| JUN | jun proto-oncogene |
| KLF5 | Kruppel-like factor 5 (intestinal) |
| KLHL2 | kelch-like family member 2 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LOC730101 | uncharacterized LOC730101 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MED7 | mediator complex subunit 7 |
| MEX3C | mex-3 RNA binding family member C |
| MORC3 | MORC family CW-type zinc finger 3 |
| MTM1 | myotubularin 1 |
| MTMR6 | myotubularin related protein 6 |
| NCKAP1 | NCK-associated protein 1 |
| NNT | nicotinamide nucleotide transhydrogenase |
| NOAZFP | nucleolar atypical zinc finger |
| NPY1R | neuropeptide Y receptor Y1 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PNISR | PNN-interacting serine/arginine-rich protein |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B |
| PTK6 | protein tyrosine kinase 6 |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| RB1CC1 | RB1-inducible coiled-coil 1 |
| RNF14 | ring finger protein 14 |
| RPL26 | ribosomal protein L26 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SOCS6 | suppressor of cytokine signaling 6 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SRSF10 | serine/arginine-rich splicing factor 10 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 |
| TGIF1 | TGFB-induced factor homeobox 1 |
| THBD | thrombomodulin |
| TMED7 | transmembrane emp24 protein transport domain containing 7 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TMEM5 | transmembrane protein 5 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) |
| TSFM | Ts translation elongation factor, mitochondrial |
| UFL1 | UFM1-specific ligase 1 |
| UHRF1BP1L | UHRF1 binding protein 1-like |
| WAPAL | wings apart-like homolog (Drosophila) |
| WWTR1 | WW domain containing transcription regulator 1 |
| YEATS4 | YEATS domain containing 4 |
| ZFX | zinc finger protein, X-linked |
| ZNF816 | zinc finger protein 816 |
| Symbol | Name |
|---|---|
| ABHD17A | abhydrolase domain containing 17A |
| ACVR2B | activin A receptor, type IIB |
| AES | amino-terminal enhancer of split |
| ALDH18A1 | aldehyde dehydrogenase 18 family, member A1 |
| ALG3 | ALG3, alpha-1,3- mannosyltransferase |
| APEH | acylaminoacyl-peptide hydrolase |
| ARL2 | ADP-ribosylation factor-like 2 |
| ASNA1 | arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) |
| AURKB | aurora kinase B |
| CAPN15 | calpain 15 |
| CAPNS1 | calpain, small subunit 1 |
| CCNL2 | cyclin L2 |
| CDC37 | cell division cycle 37 |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CHPF | chondroitin polymerizing factor |
| CLIC3 | chloride intracellular channel 3 |
| CLN3 | ceroid-lipofuscinosis, neuronal 3 |
| COLGALT1 | collagen beta(1-O)galactosyltransferase 1 |
| CRIP2 | cysteine-rich protein 2 |
| CYC1 | cytochrome c-1 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DDA1 | DET1 and DDB1 associated 1 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| DPM2 | dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit |
| EDC3 | enhancer of mRNA decapping 3 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| ERI3 | ERI1 exoribonuclease family member 3 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 |
| GPI | glucose-6-phosphate isomerase |
| GPR19 | G protein-coupled receptor 19 |
| GPS2 | G protein pathway suppressor 2 |
| GPX3 | glutathione peroxidase 3 |
| GPX4 | glutathione peroxidase 4 |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| H1FX | H1 histone family, member X |
| HDAC5 | histone deacetylase 5 |
| ILK | integrin-linked kinase |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 |
| KIAA0319L | KIAA0319-like |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B |
| MLF2 | myeloid leukemia factor 2 |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| NBEAL2 | neurobeachin-like 2 |
| NUCB1 | nucleobindin 1 |
| NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 |
| PGD | phosphogluconate dehydrogenase |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLD3 | phospholipase D family, member 3 |
| PLK1 | polo-like kinase 1 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) |
| PODXL2 | podocalyxin-like 2 |
| PPAP2C | phosphatidic acid phosphatase type 2C |
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme |
| PPP6R1 | protein phosphatase 6, regulatory subunit 1 |
| PRKCD | protein kinase C, delta |
| PRMT1 | protein arginine methyltransferase 1 |
| PRMT5 | protein arginine methyltransferase 5 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PSENEN | presenilin enhancer gamma secretase subunit |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 |
| RABGGTA | Rab geranylgeranyltransferase, alpha subunit |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RHOC | ras homolog family member C |
| RHOG | ras homolog family member G |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| SCAMP2 | secretory carrier membrane protein 2 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 |
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SMG9 | SMG9 nonsense mediated mRNA decay factor |
| SNX17 | sorting nexin 17 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TBC1D17 | TBC1 domain family, member 17 |
| TECR | trans-2,3-enoyl-CoA reductase |
| TLN1 | talin 1 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| UBE2M | ubiquitin-conjugating enzyme E2M |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| UROS | uroporphyrinogen III synthase |
| USP21 | ubiquitin specific peptidase 21 |
| XAB2 | XPA binding protein 2 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF282 | zinc finger protein 282 |
