| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the PF-00875133-00-5923 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| APOE | apolipoprotein E |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BST2 | bone marrow stromal cell antigen 2 |
| C1R | complement component 1, r subcomponent |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CLDN4 | claudin 4 |
| CREB1 | cAMP responsive element binding protein 1 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DAPK2 | death-associated protein kinase 2 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DOCK3 | dedicator of cytokinesis 3 |
| DST | dystonin |
| DUSP13 | dual specificity phosphatase 13 |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP6 | dual specificity phosphatase 6 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| ETV5 | ets variant 5 |
| ETV6 | ets variant 6 |
| FBRS | fibrosin |
| FGF23 | fibroblast growth factor 23 |
| FGFR4 | fibroblast growth factor receptor 4 |
| FRMD1 | FERM domain containing 1 |
| FSCN1 | fascin actin-bundling protein 1 |
| GID4 | GID complex subunit 4 |
| GMPR | guanosine monophosphate reductase |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| HOXD1 | homeobox D1 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KLK8 | kallikrein-related peptidase 8 |
| LRP4 | low density lipoprotein receptor-related protein 4 |
| LRRC40 | leucine rich repeat containing 40 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MAST2 | microtubule associated serine/threonine kinase 2 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
| MEFV | Mediterranean fever |
| MERTK | MER proto-oncogene, tyrosine kinase |
| MRPS12 | mitochondrial ribosomal protein S12 |
| MT1H | metallothionein 1H |
| NKX2-5 | NK2 homeobox 5 |
| P2RY11 | purinergic receptor P2Y, G-protein coupled, 11 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PCNXL2 | pecanex-like 2 (Drosophila) |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PLAA | phospholipase A2-activating protein |
| PLCH1 | phospholipase C, eta 1 |
| PLEC | plectin |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha |
| PRAMEF12 | PRAME family member 12 |
| PROSC | proline synthetase co-transcribed homolog (bacterial) |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| RAB27B | RAB27B, member RAS oncogene family |
| RABIF | RAB interacting factor |
| RANBP1 | RAN binding protein 1 |
| RARA | retinoic acid receptor, alpha |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RUSC2 | RUN and SH3 domain containing 2 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SECTM1 | secreted and transmembrane 1 |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
| SLC39A9 | solute carrier family 39, member 9 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SND1-IT1 | SND1 intronic transcript 1 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| SRPR | signal recognition particle receptor (docking protein) |
| TADA2A | transcriptional adaptor 2A |
| TBX5 | T-box 5 |
| TEP1 | telomerase-associated protein 1 |
| TLR2 | toll-like receptor 2 |
| TMEM63A | transmembrane protein 63A |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
| TOR1AIP1 | torsin A interacting protein 1 |
| TPP1 | tripeptidyl peptidase I |
| TUBG2 | tubulin, gamma 2 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) |
| WDR25 | WD repeat domain 25 |
| WDR62 | WD repeat domain 62 |
| ZNF365 | zinc finger protein 365 |
| ZNF384 | zinc finger protein 384 |
| ZNF552 | zinc finger protein 552 |
| ZNF639 | zinc finger protein 639 |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| ABCB4 | ATP-binding cassette, sub-family B (MDR/TAP), member 4 |
| ACTN4 | actinin, alpha 4 |
| ADM | adrenomedullin |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ALOX15 | arachidonate 15-lipoxygenase |
| AMT | aminomethyltransferase |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| AVPR1B | arginine vasopressin receptor 1B |
| CALML5 | calmodulin-like 5 |
| CAPN5 | calpain 5 |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CDON | cell adhesion associated, oncogene regulated |
| CEP85 | centrosomal protein 85kDa |
| CES3 | carboxylesterase 3 |
| CFD | complement factor D (adipsin) |
| CKMT2 | creatine kinase, mitochondrial 2 (sarcomeric) |
| COL16A1 | collagen, type XVI, alpha 1 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CSF1R | colony stimulating factor 1 receptor |
| CYP4F8 | cytochrome P450, family 4, subfamily F, polypeptide 8 |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| DNASE1L3 | deoxyribonuclease I-like 3 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DYSF | dysferlin |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EN2 | engrailed homeobox 2 |
| F11 | coagulation factor XI |
| FAM212B | family with sequence similarity 212, member B |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FGF4 | fibroblast growth factor 4 |
| FHIT | fragile histidine triad |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GAPDHS | glyceraldehyde-3-phosphate dehydrogenase, spermatogenic |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| HDAC11 | histone deacetylase 11 |
| HOXA10 | homeobox A10 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IGSF6 | immunoglobulin superfamily, member 6 |
| INCENP | inner centromere protein antigens 135/155kDa |
| IRS4 | insulin receptor substrate 4 |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KLK5 | kallikrein-related peptidase 5 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LOC157562 | uncharacterized LOC157562 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MLLT4-AS1 | MLLT4 antisense RNA 1 (head to head) |
| MORN1 | MORN repeat containing 1 |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MSI1 | musashi RNA-binding protein 1 |
| MYF5 | myogenic factor 5 |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| ONECUT2 | one cut homeobox 2 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PARPBP | PARP1 binding protein |
| PCDHB12 | protocadherin beta 12 |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PNPLA3 | patatin-like phospholipase domain containing 3 |
| PRAMEF10 | PRAME family member 10 |
| PRF1 | perforin 1 (pore forming protein) |
| PRKCE | protein kinase C, epsilon |
| PROL1 | proline rich, lacrimal 1 |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| RAB30 | RAB30, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| S100A12 | S100 calcium binding protein A12 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SP1 | Sp1 transcription factor |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STON1 | stonin 1 |
| TAS2R3 | taste receptor, type 2, member 3 |
| TCTN2 | tectonic family member 2 |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
| TMEM254 | transmembrane protein 254 |
| TPK1 | thiamin pyrophosphokinase 1 |
| WNT1 | wingless-type MMTV integration site family, member 1 |
| YIPF5 | Yip1 domain family, member 5 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZBTB22 | zinc finger and BTB domain containing 22 |