| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the PF-00875133-00-5928 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABR | active BCR-related |
| ACACA | acetyl-CoA carboxylase alpha |
| ADAM10 | ADAM metallopeptidase domain 10 |
| AIM1L | absent in melanoma 1-like |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARHGEF9 | Cdc42 guanine nucleotide exchange factor (GEF) 9 |
| C3 | complement component 3 |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| CCDC121 | coiled-coil domain containing 121 |
| CCPG1 | cell cycle progression 1 |
| CDC25A | cell division cycle 25A |
| CDC42 | cell division cycle 42 |
| CDH7 | cadherin 7, type 2 |
| CDK10 | cyclin-dependent kinase 10 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CIDEC | cell death-inducing DFFA-like effector c |
| CROCC | ciliary rootlet coiled-coil, rootletin |
| DDN | dendrin |
| DNAH3 | dynein, axonemal, heavy chain 3 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| EFNA3 | ephrin-A3 |
| EFNB1 | ephrin-B1 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FAM89B | family with sequence similarity 89, member B |
| FLJ42627 | uncharacterized LOC645644 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GFOD2 | glucose-fructose oxidoreductase domain containing 2 |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GTDC1 | glycosyltransferase-like domain containing 1 |
| HAUS5 | HAUS augmin-like complex, subunit 5 |
| HIST1H3G | histone cluster 1, H3g |
| HNMT | histamine N-methyltransferase |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IL17RC | interleukin 17 receptor C |
| KDM6B | lysine (K)-specific demethylase 6B |
| KIF16B | kinesin family member 16B |
| KLF6 | Kruppel-like factor 6 |
| LOC100294391 | uncharacterized LOC100294391 |
| LPIN1 | lipin 1 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAPT | microtubule-associated protein tau |
| MINK1 | misshapen-like kinase 1 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MST1 | macrophage stimulating 1 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| MTUS1 | microtubule associated tumor suppressor 1 |
| MUC3B | mucin 3B, cell surface associated |
| MYO1B | myosin IB |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NOL10 | nucleolar protein 10 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| NUP160 | nucleoporin 160kDa |
| NUP50 | nucleoporin 50kDa |
| NUP54 | nucleoporin 54kDa |
| NXT2 | nuclear transport factor 2-like export factor 2 |
| OSR2 | odd-skipped related transciption factor 2 |
| PARVA | parvin, alpha |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PLCH1 | phospholipase C, eta 1 |
| PLIN2 | perilipin 2 |
| POU5F1B | POU class 5 homeobox 1B |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) |
| RAB33B | RAB33B, member RAS oncogene family |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNMT | RNA (guanine-7-) methyltransferase |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| RPS28 | ribosomal protein S28 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SMIM8 | small integral membrane protein 8 |
| SNX15 | sorting nexin 15 |
| STK17A | serine/threonine kinase 17a |
| TAPBP | TAP binding protein (tapasin) |
| TMEM209 | transmembrane protein 209 |
| TMEM53 | transmembrane protein 53 |
| TMEM8B | transmembrane protein 8B |
| TNS1 | tensin 1 |
| URI1 | URI1, prefoldin-like chaperone |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked |
| VGF | VGF nerve growth factor inducible |
| WDR48 | WD repeat domain 48 |
| ZBED4 | zinc finger, BED-type containing 4 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF10 | zinc finger protein 10 |
| ZNF268 | zinc finger protein 268 |
| ZNF710 | zinc finger protein 710 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ALS2CL | ALS2 C-terminal like |
| AMPH | amphiphysin |
| ANXA10 | annexin A10 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARL14 | ADP-ribosylation factor-like 14 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C1S | complement component 1, s subcomponent |
| C4ORF19 | chromosome 4 open reading frame 19 |
| C8A | complement component 8, alpha polypeptide |
| CADPS2 | Ca++-dependent secretion activator 2 |
| CCDC57 | coiled-coil domain containing 57 |
| CD1C | CD1c molecule |
| CD68 | CD68 molecule |
| CD70 | CD70 molecule |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CYB5R2 | cytochrome b5 reductase 2 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DENND2D | DENN/MADD domain containing 2D |
| EFCAB2 | EF-hand calcium binding domain 2 |
| EGR2 | early growth response 2 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| EXOSC1 | exosome component 1 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM105A | family with sequence similarity 105, member A |
| FGF6 | fibroblast growth factor 6 |
| FLT4 | fms-related tyrosine kinase 4 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GPT | glutamic-pyruvate transaminase (alanine aminotransferase) |
| GPX2 | glutathione peroxidase 2 |
| GRM4 | glutamate receptor, metabotropic 4 |
| HDAC11 | histone deacetylase 11 |
| HDAC9 | histone deacetylase 9 |
| HIST1H2AI | histone cluster 1, H2ai |
| HOXA3 | homeobox A3 |
| HOXB2 | homeobox B2 |
| IBSP | integrin-binding sialoprotein |
| IL15RA | interleukin 15 receptor, alpha |
| IL17RA | interleukin 17 receptor A |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIAA1462 | KIAA1462 |
| KLHL36 | kelch-like family member 36 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LOC257152 | uncharacterized LOC257152 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| MAGEF1 | melanoma antigen family F1 |
| MAGIX | MAGI family member, X-linked |
| METTL16 | methyltransferase like 16 |
| MFI2 | antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 |
| MILR1 | mast cell immunoglobulin-like receptor 1 |
| MIR622 | microRNA 622 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MTCP1 | mature T-cell proliferation 1 |
| NAG18 | NAG18 mRNA |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OR10H1 | olfactory receptor, family 10, subfamily H, member 1 |
| OSMR | oncostatin M receptor |
| PADI1 | peptidyl arginine deiminase, type I |
| PALM | paralemmin |
| PCBP4 | poly(rC) binding protein 4 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| PRR14L | proline rich 14-like |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RAB25 | RAB25, member RAS oncogene family |
| RAB36 | RAB36, member RAS oncogene family |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| REC8 | REC8 meiotic recombination protein |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCIN | scinderin |
| SLC17A4 | solute carrier family 17, member 4 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SNRPN | small nuclear ribonucleoprotein polypeptide N |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAOK1 | TAO kinase 1 |
| TENM4 | teneurin transmembrane protein 4 |
| TGM1 | transglutaminase 1 |
| TLR4 | toll-like receptor 4 |
| TUBA4B | tubulin, alpha 4b |
| URGCP | upregulator of cell proliferation |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZFHX2 | zinc finger homeobox 2 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF711 | zinc finger protein 711 |
| ZNF816 | zinc finger protein 816 |
