| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the PF-01378883-00-6405 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSBG1 | acyl-CoA synthetase bubblegum family member 1 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADCY2 | adenylate cyclase 2 (brain) |
| AEBP1 | AE binding protein 1 |
| AK1 | adenylate kinase 1 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| AMPD1 | adenosine monophosphate deaminase 1 |
| APOE | apolipoprotein E |
| ARHGAP24 | Rho GTPase activating protein 24 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide |
| BCL3 | B-cell CLL/lymphoma 3 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| BTN3A3 | butyrophilin, subfamily 3, member A3 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| C1RL | complement component 1, r subcomponent-like |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CD69 | CD69 molecule |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CDK6 | cyclin-dependent kinase 6 |
| CHM | choroideremia (Rab escort protein 1) |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| DOCK5 | dedicator of cytokinesis 5 |
| DOCK9 | dedicator of cytokinesis 9 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DSC3 | desmocollin 3 |
| DUSP6 | dual specificity phosphatase 6 |
| ELAVL2 | ELAV like neuron-specific RNA binding protein 2 |
| ETV5 | ets variant 5 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FHL1 | four and a half LIM domains 1 |
| FPR1 | formyl peptide receptor 1 |
| FSHB | follicle stimulating hormone, beta polypeptide |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GOSR2 | golgi SNAP receptor complex member 2 |
| GPC3 | glypican 3 |
| HIST1H4E | histone cluster 1, H4e |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HRH3 | histamine receptor H3 |
| ICAM1 | intercellular adhesion molecule 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFNG | interferon, gamma |
| IRF4 | interferon regulatory factor 4 |
| ITGB4 | integrin, beta 4 |
| KIAA1467 | KIAA1467 |
| LEFTY2 | left-right determination factor 2 |
| LMNA | lamin A/C |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| LRRC17 | leucine rich repeat containing 17 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MALL | mal, T-cell differentiation protein-like |
| MAP2 | microtubule-associated protein 2 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MFSD7 | major facilitator superfamily domain containing 7 |
| MMP11 | matrix metallopeptidase 11 |
| MSI1 | musashi RNA-binding protein 1 |
| NME8 | NME/NM23 family member 8 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| NRP2 | neuropilin 2 |
| NTF3 | neurotrophin 3 |
| P3H2 | prolyl 3-hydroxylase 2 |
| PADI3 | peptidyl arginine deiminase, type III |
| PCDHB3 | protocadherin beta 3 |
| PHTF2 | putative homeodomain transcription factor 2 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLIN2 | perilipin 2 |
| PLTP | phospholipid transfer protein |
| PQLC3 | PQ loop repeat containing 3 |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| PTK2B | protein tyrosine kinase 2 beta |
| RBM12B | RNA binding motif protein 12B |
| RBM48 | RNA binding motif protein 48 |
| RFXAP | regulatory factor X-associated protein |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SLC25A16 | solute carrier family 25 (mitochondrial carrier), member 16 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SMOX | spermine oxidase |
| SPEG | SPEG complex locus |
| SPON1 | spondin 1, extracellular matrix protein |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TGM2 | transglutaminase 2 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TSC22D2 | TSC22 domain family, member 2 |
| TTC38 | tetratricopeptide repeat domain 38 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR78 | WD repeat domain 78 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| YTHDC2 | YTH domain containing 2 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALOX12 | arachidonate 12-lipoxygenase |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| ATP6V1B1 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BCL2A1 | BCL2-related protein A1 |
| BCO1 | beta-carotene oxygenase 1 |
| BMP15 | bone morphogenetic protein 15 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| CACNG3 | calcium channel, voltage-dependent, gamma subunit 3 |
| CCL19 | chemokine (C-C motif) ligand 19 |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDK3 | cyclin-dependent kinase 3 |
| CDO1 | cysteine dioxygenase type 1 |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CLCA3P | chloride channel accessory 3, pseudogene |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLSTN3 | calsyntenin 3 |
| CNTD2 | cyclin N-terminal domain containing 2 |
| COL15A1 | collagen, type XV, alpha 1 |
| CPA2 | carboxypeptidase A2 (pancreatic) |
| DAGLA | diacylglycerol lipase, alpha |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DMRT1 | doublesex and mab-3 related transcription factor 1 |
| DSPP | dentin sialophosphoprotein |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| ERCC2 | excision repair cross-complementation group 2 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| FAM198B | family with sequence similarity 198, member B |
| FAM212B | family with sequence similarity 212, member B |
| FBXO2 | F-box protein 2 |
| FGF4 | fibroblast growth factor 4 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GARNL3 | GTPase activating Rap/RanGAP domain-like 3 |
| GOLGA6A | golgin A6 family, member A |
| GPR15 | G protein-coupled receptor 15 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| HIST1H3I | histone cluster 1, H3i |
| HIST1H4F | histone cluster 1, H4f |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HOXA4 | homeobox A4 |
| HOXC5 | homeobox C5 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IL36RN | interleukin 36 receptor antagonist |
| IQCC | IQ motif containing C |
| ITGA8 | integrin, alpha 8 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KIAA0125 | KIAA0125 |
| KLF2 | Kruppel-like factor 2 |
| LHX1 | LIM homeobox 1 |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MIP | major intrinsic protein of lens fiber |
| MLN | motilin |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| MPP1 | membrane protein, palmitoylated 1, 55kDa |
| NCF1C | neutrophil cytosolic factor 1C pseudogene |
| NEUROD4 | neuronal differentiation 4 |
| NPPA | natriuretic peptide A |
| NTRK1 | neurotrophic tyrosine kinase, receptor, type 1 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PENK | proenkephalin |
| PEX5L | peroxisomal biogenesis factor 5-like |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PIN1P1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| POF1B | premature ovarian failure, 1B |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PRLH | prolactin releasing hormone |
| PRO2964 | uncharacterized protein PRO2964 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PURG | purine-rich element binding protein G |
| QPCT | glutaminyl-peptide cyclotransferase |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RDH16 | retinol dehydrogenase 16 (all-trans) |
| SDC3 | syndecan 3 |
| SERPINF2 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 |
| SLC5A12 | solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12 |
| STAC | SH3 and cysteine rich domain |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TLR5 | toll-like receptor 5 |
| TMC5 | transmembrane channel-like 5 |
| TMEM206 | transmembrane protein 206 |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TRIM36 | tripartite motif containing 36 |
| TSGA10 | testis specific, 10 |
| TUBB2B | tubulin, beta 2B class IIb |
| ZNF155 | zinc finger protein 155 |
