PF-01378883-00-6410 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the PF-01378883-00-6410 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
AKR1C1 aldo-keto reductase family 1, member C1
ANKLE2 ankyrin repeat and LEM domain containing 2
APOL6 apolipoprotein L, 6
APOLD1 apolipoprotein L domain containing 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ASTN2 astrotactin 2
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
ATP9A ATPase, class II, type 9A
B3GAT3 beta-1,3-glucuronyltransferase 3
C8ORF60 chromosome 8 open reading frame 60
CAPN10 calpain 10
CASZ1 castor zinc finger 1
CCHCR1 coiled-coil alpha-helical rod protein 1
CD82 CD82 molecule
CFAP69 cilia and flagella associated protein 69
CHD3 chromodomain helicase DNA binding protein 3
CHRDL1 chordin-like 1
CISH cytokine inducible SH2-containing protein
CLEC11A C-type lectin domain family 11, member A
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CUL7 cullin 7
CUZD1 CUB and zona pellucida-like domains 1
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DOCK5 dedicator of cytokinesis 5
DOCK6 dedicator of cytokinesis 6
ECE1 endothelin converting enzyme 1
ECM1 extracellular matrix protein 1
ELF4 E74-like factor 4 (ets domain transcription factor)
ERP44 endoplasmic reticulum protein 44
FAM50B family with sequence similarity 50, member B
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GABARAPL1 GABA(A) receptor-associated protein like 1
GAS7 growth arrest-specific 7
GLS2 glutaminase 2 (liver, mitochondrial)
GPM6B glycoprotein M6B
HSF2 heat shock transcription factor 2
IFT122 intraflagellar transport 122
IFT27 intraflagellar transport 27
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL7 interleukin 7
MAP2K5 mitogen-activated protein kinase kinase 5
MAPK11 mitogen-activated protein kinase 11
MDFIC MyoD family inhibitor domain containing
MOCS3 molybdenum cofactor synthesis 3
MSL3 male-specific lethal 3 homolog (Drosophila)
MYH14 myosin, heavy chain 14, non-muscle
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NEK11 NIMA-related kinase 11
NPFFR1 neuropeptide FF receptor 1
NPR2 natriuretic peptide receptor 2
NR2C1 nuclear receptor subfamily 2, group C, member 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OASL 2'-5'-oligoadenylate synthetase-like
PACS1 phosphofurin acidic cluster sorting protein 1
PADI1 peptidyl arginine deiminase, type I
PAIP2B poly(A) binding protein interacting protein 2B
PAQR6 progestin and adipoQ receptor family member VI
PCOLCE procollagen C-endopeptidase enhancer
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PFDN4 prefoldin subunit 4
PLK3 polo-like kinase 3
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRR4 proline rich 4 (lacrimal)
PRRC2B proline-rich coiled-coil 2B
PRSS16 protease, serine, 16 (thymus)
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTK6 protein tyrosine kinase 6
RAB17 RAB17, member RAS oncogene family
REPS1 RALBP1 associated Eps domain containing 1
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RHOBTB2 Rho-related BTB domain containing 2
RNF122 ring finger protein 122
SBF1 SET binding factor 1
SOGA1 suppressor of glucose, autophagy associated 1
SPN sialophorin
ST20 suppressor of tumorigenicity 20
STK17A serine/threonine kinase 17a
STS steroid sulfatase (microsomal), isozyme S
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TMEM231 transmembrane protein 231
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TRAIP TRAF interacting protein
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSC22D4 TSC22 domain family, member 4
TUBA3C tubulin, alpha 3c
U2SURP U2 snRNP-associated SURP domain containing
UBOX5 U-box domain containing 5
WDR61 WD repeat domain 61
WSB1 WD repeat and SOCS box containing 1
YTHDC1 YTH domain containing 1
ZNF37BP zinc finger protein 37B, pseudogene
ZNF74 zinc finger protein 74
ZNHIT2 zinc finger, HIT-type containing 2

decreased expression

Symbol Name
ADGRF1 adhesion G protein-coupled receptor F1
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARL15 ADP-ribosylation factor-like 15
ARPIN actin-related protein 2/3 complex inhibitor
ARRB2 arrestin, beta 2
ARSA arylsulfatase A
ATP7B ATPase, Cu++ transporting, beta polypeptide
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BST1 bone marrow stromal cell antigen 1
C16ORF62 chromosome 16 open reading frame 62
C17ORF53 chromosome 17 open reading frame 53
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CCDC71 coiled-coil domain containing 71
CD80 CD80 molecule
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHI3L2 chitinase 3-like 2
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLDN14 claudin 14
CST4 cystatin S
CST6 cystatin E/M
CXCL3 chemokine (C-X-C motif) ligand 3
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DGKE diacylglycerol kinase, epsilon 64kDa
DMBT1 deleted in malignant brain tumors 1
DPF1 D4, zinc and double PHD fingers family 1
DRD1 dopamine receptor D1
DSCAM Down syndrome cell adhesion molecule
ELOVL4 ELOVL fatty acid elongase 4
EPN3 epsin 3
FAM120C family with sequence similarity 120C
FKBP10 FK506 binding protein 10, 65 kDa
FLT4 fms-related tyrosine kinase 4
FOXO4 forkhead box O4
GBA3 glucosidase, beta, acid 3 (gene/pseudogene)
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GPR1 G protein-coupled receptor 1
GPR183 G protein-coupled receptor 183
GRIP2 glutamate receptor interacting protein 2
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene)
HCG9 HLA complex group 9 (non-protein coding)
HDAC11 histone deacetylase 11
HDAC7 histone deacetylase 7
HHIPL2 HHIP-like 2
HIST1H2AG histone cluster 1, H2ag
IPO8 importin 8
IRAK4 interleukin-1 receptor-associated kinase 4
KRT24 keratin 24, type I
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LSP1 lymphocyte-specific protein 1
LY96 lymphocyte antigen 96
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MUC3B mucin 3B, cell surface associated
NPM3 nucleophosmin/nucleoplasmin 3
NPY1R neuropeptide Y receptor Y1
OGFRL1 opioid growth factor receptor-like 1
OLFML3 olfactomedin-like 3
OSMR oncostatin M receptor
OSR2 odd-skipped related transciption factor 2
PAX9 paired box 9
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PICK1 protein interacting with PRKCA 1
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PODXL2 podocalyxin-like 2
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
POMT2 protein-O-mannosyltransferase 2
PRAF2 PRA1 domain family, member 2
PRB3 proline-rich protein BstNI subfamily 3
PRR3 proline rich 3
PRR7 proline rich 7 (synaptic)
PRSS22 protease, serine, 22
R3HCC1L R3H domain and coiled-coil containing 1-like
RABL6 RAB, member RAS oncogene family-like 6
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RARS arginyl-tRNA synthetase
RNF208 ring finger protein 208
SCN10A sodium channel, voltage gated, type X alpha subunit
SETBP1 SET binding protein 1
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SOX12 SRY (sex determining region Y)-box 12
SPRR1B small proline-rich protein 1B
STRA6 stimulated by retinoic acid 6
TAC3 tachykinin 3
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCTN1 tectonic family member 1
TEX40 testis expressed 40
THRAP3 thyroid hormone receptor associated protein 3
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMEM209 transmembrane protein 209
TRIM25 tripartite motif containing 25
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TUBB2B tubulin, beta 2B class IIb
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WNT7A wingless-type MMTV integration site family, member 7A