| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | PF-06260933 perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the PF-06260933_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LSAMP | limbic system-associated membrane protein | 0.0592992 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0564142 |
| TLE4 | transducin-like enhancer of split 4 | 0.0476969 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0409838 |
| FMN1 | formin 1 | 0.0407163 |
| PLAT | plasminogen activator, tissue | 0.0376166 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0320109 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0301468 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.028585 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0284522 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0268787 |
| DST | dystonin | 0.0260318 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0255706 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0243139 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0231634 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0218577 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0217444 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0217325 |
| VMP1 | vacuole membrane protein 1 | 0.0216709 |
| NRG1 | neuregulin 1 | 0.0215452 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0212664 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0211789 |
| RNF213 | ring finger protein 213 | 0.0211429 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0211014 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0208164 |
| YEATS2 | YEATS domain containing 2 | 0.019763 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0191265 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0188748 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0188659 |
| BPTF | bromodomain PHD finger transcription factor | 0.0185722 |
| AHR | aryl hydrocarbon receptor | 0.0184551 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0180913 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0179394 |
| DPH6 | diphthamine biosynthesis 6 | 0.0175342 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0173701 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0169994 |
| CALD1 | caldesmon 1 | 0.0167505 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0165771 |
| PRKD1 | protein kinase D1 | 0.016412 |
| MEF2A | myocyte enhancer factor 2A | 0.0163302 |
| ZNF638 | zinc finger protein 638 | 0.0162756 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0160245 |
| VCL | vinculin | 0.015974 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0159648 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0156455 |
| PHF3 | PHD finger protein 3 | 0.0156218 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0152922 |
| SYT1 | synaptotagmin I | 0.0152738 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0152246 |
| FAM13A | family with sequence similarity 13, member A | 0.0151979 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0149405 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0148482 |
| INTS6 | integrator complex subunit 6 | 0.014797 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0146738 |
| SMAD3 | SMAD family member 3 | 0.0144033 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0142185 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0141195 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0139916 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0139305 |
| FAM107B | family with sequence similarity 107, member B | 0.0138804 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0135088 |
| RUNX1 | runt-related transcription factor 1 | 0.0134613 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0133303 |
| RAD51B | RAD51 paralog B | 0.0132337 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.013112 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0130618 |
| ATM | ATM serine/threonine kinase | 0.0129413 |
| RALYL | RALY RNA binding protein-like | 0.0127262 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0124703 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0122524 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.0121886 |
| MKI67 | marker of proliferation Ki-67 | 0.0121144 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.0121131 |
| GPC5 | glypican 5 | 0.0120995 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.012073 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0120453 |
| VEGFA | vascular endothelial growth factor A | 0.0120254 |
| TCF12 | transcription factor 12 | 0.0119734 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0115183 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0113683 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0113358 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0113085 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0112225 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0111811 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0110705 |
| MTREX | Mtr4 exosome RNA helicase | 0.0110545 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0110489 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0109568 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0108869 |
| GPATCH2L | G patch domain containing 2-like | 0.0107922 |
| PCNX1 | pecanex 1 | 0.0107501 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.010722 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0105635 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0105612 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0105596 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0105095 |
| SMYD3 | SET and MYND domain containing 3 | 0.0105018 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0103282 |
| FOXP1 | forkhead box P1 | 0.0102784 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.0102439 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.311032 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.120607 |
| VIM | vimentin | -0.0829043 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.067213 |
| PTMA | prothymosin, alpha | -0.0543012 |
| RPS6 | ribosomal protein S6 | -0.0474387 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.045203 |
| RPLP1 | ribosomal protein, large, P1 | -0.0393741 |
| WDR45B | WD repeat domain 45B | -0.0381617 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0380415 |
| GNAS | GNAS complex locus | -0.0311335 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0307225 |
| LPIN1 | lipin 1 | -0.027754 |
| CANX | calnexin | -0.0271605 |
| IGF2 | insulin-like growth factor 2 | -0.0265235 |
| RPL35A | ribosomal protein L35a | -0.0259006 |
| RPS19 | ribosomal protein S19 | -0.0257186 |
| TMSB10 | thymosin beta 10 | -0.025249 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0250306 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0238887 |
| FTL | ferritin, light polypeptide | -0.0233401 |
| NDRG1 | N-myc downstream regulated 1 | -0.0231813 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0231184 |
| RPL34 | ribosomal protein L34 | -0.0231058 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0230021 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0223854 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0220108 |
| POTEF | POTE ankyrin domain family, member F | -0.0219656 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0216972 |
| DSTN | destrin (actin depolymerizing factor) | -0.0216808 |
| GLG1 | golgi glycoprotein 1 | -0.0214696 |
| RPS12 | ribosomal protein S12 | -0.0214408 |
| RPL12 | ribosomal protein L12 | -0.0211291 |
| RPL26 | ribosomal protein L26 | -0.0208602 |
| RPS16 | ribosomal protein S16 | -0.0208494 |
| SCG2 | secretogranin II | -0.0203666 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.020364 |
| RPL32 | ribosomal protein L32 | -0.0197856 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0194293 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0193165 |
| RPS24 | ribosomal protein S24 | -0.019271 |
| RPLP0 | ribosomal protein, large, P0 | -0.0190589 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0189505 |
| PTK2 | protein tyrosine kinase 2 | -0.0186633 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0185375 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0181274 |
| ASPH | aspartate beta-hydroxylase | -0.0180499 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0180491 |
| S100A9 | S100 calcium binding protein A9 | -0.0174641 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0173842 |
| RPL23 | ribosomal protein L23 | -0.0171433 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0169962 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.01676 |
| PFN1 | profilin 1 | -0.01658 |
| MAP1B | microtubule-associated protein 1B | -0.0164626 |
| RPL37 | ribosomal protein L37 | -0.0163972 |
| RPS25 | ribosomal protein S25 | -0.0160207 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0160074 |
| OGA | O-GlcNAcase | -0.0158945 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0158082 |
| VDAC1 | voltage-dependent anion channel 1 | -0.015443 |
| RPS14 | ribosomal protein S14 | -0.0153948 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0151231 |
| USP3 | ubiquitin specific peptidase 3 | -0.015117 |
| RPS3 | ribosomal protein S3 | -0.015051 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0148544 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0148197 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0147513 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0146924 |
| ANXA2 | annexin A2 | -0.0146734 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0146291 |
| UBC | ubiquitin C | -0.0145771 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0144521 |
| RPL13A | ribosomal protein L13a | -0.0143999 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0143819 |
| RYBP | RING1 and YY1 binding protein | -0.014219 |
| SERF2 | small EDRK-rich factor 2 | -0.0139422 |
| RPL28 | ribosomal protein L28 | -0.0137646 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0136611 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0136338 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0136243 |
| RPL31 | ribosomal protein L31 | -0.0136219 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0135469 |
| DACH2 | dachshund family transcription factor 2 | -0.0134508 |
| B2M | beta-2-microglobulin | -0.0134489 |
| USP34 | ubiquitin specific peptidase 34 | -0.0134324 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0131434 |
| TMEM123 | transmembrane protein 123 | -0.0130419 |
| RLF | rearranged L-myc fusion | -0.0129845 |
| CCND1 | cyclin D1 | -0.0129843 |
| GOLGA4 | golgin A4 | -0.0129665 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0129577 |
| YBX1 | Y box binding protein 1 | -0.0128777 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | -0.012869 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0127021 |
| COPA | coatomer protein complex, subunit alpha | -0.0126356 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0126001 |
| KLHL24 | kelch-like family member 24 | -0.0124838 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | -0.0124809 |
| RPL35 | ribosomal protein L35 | -0.0124728 |
