| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | PF-06260933 perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the PF-06260933_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.163539 |
| FLNB | filamin B, beta | 0.154465 |
| MTSS1 | metastasis suppressor 1 | 0.107893 |
| LAMC2 | laminin, gamma 2 | 0.0966809 |
| PODXL | podocalyxin-like | 0.091359 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0852727 |
| PLEC | plectin | 0.0814801 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0808209 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0802097 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0774837 |
| AHNAK | AHNAK nucleoprotein | 0.0728114 |
| LMO7 | LIM domain 7 | 0.0694456 |
| SMAD3 | SMAD family member 3 | 0.0629377 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0623946 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0582395 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0539136 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0537113 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.052488 |
| RAI14 | retinoic acid induced 14 | 0.0523945 |
| CDK6 | cyclin-dependent kinase 6 | 0.0509128 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0495057 |
| INTS6 | integrator complex subunit 6 | 0.0491301 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0487226 |
| RASAL2 | RAS protein activator like 2 | 0.0463831 |
| AMOTL1 | angiomotin like 1 | 0.0461016 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0447715 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0443533 |
| DOCK5 | dedicator of cytokinesis 5 | 0.044129 |
| ASPH | aspartate beta-hydroxylase | 0.043458 |
| OSMR | oncostatin M receptor | 0.042544 |
| SULF2 | sulfatase 2 | 0.0423943 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0414083 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0406687 |
| PRELID2 | PRELI domain containing 2 | 0.0389682 |
| NAV2 | neuron navigator 2 | 0.0386908 |
| MSN | moesin | 0.0382568 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.038231 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0379965 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.036024 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0358739 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0352778 |
| SQSTM1 | sequestosome 1 | 0.0349858 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0345179 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0337204 |
| EFNA5 | ephrin-A5 | 0.0330727 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0328403 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0325797 |
| ACTN1 | actinin, alpha 1 | 0.0323883 |
| HMGA2 | high mobility group AT-hook 2 | 0.0323195 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.032191 |
| SMYD3 | SET and MYND domain containing 3 | 0.032136 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0313919 |
| RNF217 | ring finger protein 217 | 0.0296896 |
| EFNB2 | ephrin-B2 | 0.0295186 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0294715 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0292809 |
| LUZP1 | leucine zipper protein 1 | 0.0292372 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0291822 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0288205 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0286972 |
| BLCAP | bladder cancer associated protein | 0.0284924 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0284203 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0283717 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.028241 |
| JAG1 | jagged 1 | 0.028186 |
| FN1 | fibronectin 1 | 0.0280893 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0276815 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0271931 |
| MECOM | MDS1 and EVI1 complex locus | 0.0271877 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0271345 |
| SH3PXD2A | SH3 and PX domains 2A | 0.026819 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0267006 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0265174 |
| PLXNA2 | plexin A2 | 0.0264886 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.026331 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0261846 |
| VEGFA | vascular endothelial growth factor A | 0.0261742 |
| APP | amyloid beta (A4) precursor protein | 0.0261364 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0260138 |
| AOPEP | aminopeptidase O (putative) | 0.0258409 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0258159 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0254562 |
| HLA-B | major histocompatibility complex, class I, B | 0.0254228 |
| FOXO1 | forkhead box O1 | 0.0248262 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0248056 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0246639 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.024582 |
| CMIP | c-Maf inducing protein | 0.024382 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0242928 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0242608 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0241013 |
| LDHA | lactate dehydrogenase A | 0.0240724 |
| KIAA0040 | KIAA0040 | 0.0239729 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0232079 |
| ATXN1 | ataxin 1 | 0.0230282 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0224204 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0223295 |
| THBD | thrombomodulin | 0.0222782 |
| FLNA | filamin A, alpha | 0.0222165 |
| RASA3 | RAS p21 protein activator 3 | 0.0222063 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.13514 |
| CLU | clusterin | -0.107389 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0738062 |
| POTEF | POTE ankyrin domain family, member F | -0.0685409 |
| PTMA | prothymosin, alpha | -0.0640489 |
| MEF2A | myocyte enhancer factor 2A | -0.0544197 |
| MT2A | metallothionein 2A | -0.0521987 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0509443 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0501663 |
| RPS6 | ribosomal protein S6 | -0.0496451 |
| B2M | beta-2-microglobulin | -0.0490577 |
| DSTN | destrin (actin depolymerizing factor) | -0.0487487 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0483575 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0482777 |
| MT1X | metallothionein 1X | -0.0479688 |
| S100A10 | S100 calcium binding protein A10 | -0.0465181 |
| GOLGA4 | golgin A4 | -0.0417943 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0407469 |
| S100A6 | S100 calcium binding protein A6 | -0.0403689 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.039008 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0387164 |
| TMSB10 | thymosin beta 10 | -0.0365978 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0365671 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.036155 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.0354856 |
| TXNIP | thioredoxin interacting protein | -0.0353122 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0347263 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0342863 |
| TPX2 | TPX2, microtubule-associated | -0.0330541 |
| ANLN | anillin, actin binding protein | -0.0328391 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.032241 |
| YBX1 | Y box binding protein 1 | -0.0320783 |
| VDAC1 | voltage-dependent anion channel 1 | -0.03193 |
| GNAS | GNAS complex locus | -0.0317071 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0316403 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0314502 |
| SPAG9 | sperm associated antigen 9 | -0.0313282 |
| ANXA1 | annexin A1 | -0.0308855 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0306789 |
| FTL | ferritin, light polypeptide | -0.0306584 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0304066 |
| KRT17 | keratin 17, type I | -0.0299299 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0299201 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0296887 |
| PFN1 | profilin 1 | -0.0292882 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0291783 |
| NDRG1 | N-myc downstream regulated 1 | -0.0290877 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0290035 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0289977 |
| TAGLN2 | transgelin 2 | -0.0288428 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0282988 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0281967 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0280659 |
| RNF145 | ring finger protein 145 | -0.0280101 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0279057 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0274371 |
| WASF2 | WAS protein family, member 2 | -0.0268458 |
| MORF4L2 | mortality factor 4 like 2 | -0.0267314 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0265173 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0264753 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0264626 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0264017 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0262968 |
| S100A9 | S100 calcium binding protein A9 | -0.0262159 |
| H1-0 | H1.0 linker histone | -0.0262024 |
| GLYAT | glycine-N-acyltransferase | -0.0260222 |
| RPS13 | ribosomal protein S13 | -0.0257922 |
| RPLP0 | ribosomal protein, large, P0 | -0.0254738 |
| ITM2B | integral membrane protein 2B | -0.025437 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0250175 |
| ITGA6 | integrin, alpha 6 | -0.0248539 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0246977 |
| DENND4C | DENN/MADD domain containing 4C | -0.0245923 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0245894 |
| XPO1 | exportin 1 | -0.0245398 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0245321 |
| CD99 | CD99 molecule | -0.0238727 |
| TMEM165 | transmembrane protein 165 | -0.0234131 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0231022 |
| RPLP2 | ribosomal protein, large, P2 | -0.0230118 |
| RPL27A | ribosomal protein L27a | -0.0228833 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0226641 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.02194 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.021904 |
| SRP54 | signal recognition particle 54kDa | -0.0218809 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.0218488 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.0218035 |
| RPLP1 | ribosomal protein, large, P1 | -0.021718 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0215785 |
| CENPF | centromere protein F, 350/400kDa | -0.0215778 |
| TMEM123 | transmembrane protein 123 | -0.0214288 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0212801 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0211119 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.0210226 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0210201 |
| YBX3 | Y box binding protein 3 | -0.0208398 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.020724 |
| RIOK3 | RIO kinase 3 | -0.0204745 |
| CANX | calnexin | -0.0203971 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.020358 |
