| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | PF-06260933 perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the PF-06260933_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PRKCA | protein kinase C, alpha | 0.0991457 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0786536 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.071138 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0612367 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0570094 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.056708 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0562433 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0555006 |
| DTNA | dystrobrevin, alpha | 0.0522884 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0491345 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0475261 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.04655 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0452694 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0452169 |
| NAV3 | neuron navigator 3 | 0.0445312 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0438562 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0435697 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0427518 |
| PGK1 | phosphoglycerate kinase 1 | 0.0411724 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0395798 |
| LDHA | lactate dehydrogenase A | 0.0390524 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0388761 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0388686 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0382071 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0376305 |
| ATXN1 | ataxin 1 | 0.0371719 |
| BRD2 | bromodomain containing 2 | 0.0364457 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0362089 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | 0.0350195 |
| GOLGB1 | golgin B1 | 0.0347508 |
| FLNB | filamin B, beta | 0.0345703 |
| INTS6 | integrator complex subunit 6 | 0.0345055 |
| MSN | moesin | 0.0332234 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0331287 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0322282 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0315141 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0314674 |
| RBM39 | RNA binding motif protein 39 | 0.0285144 |
| HLA-A | major histocompatibility complex, class I, A | 0.0280747 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0280152 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0279147 |
| CAPRIN2 | caprin family member 2 | 0.0273887 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0273797 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0267956 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0265371 |
| VEGFA | vascular endothelial growth factor A | 0.0261413 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0260196 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0258327 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0257816 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0256229 |
| RPS3 | ribosomal protein S3 | 0.0252799 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0250592 |
| BRD4 | bromodomain containing 4 | 0.0249506 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0246786 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0243254 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0241898 |
| NDRG1 | N-myc downstream regulated 1 | 0.0241661 |
| NAV2 | neuron navigator 2 | 0.0239704 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0239178 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0236073 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0234693 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0231252 |
| SMAD3 | SMAD family member 3 | 0.0231219 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 | 0.0229993 |
| ITGA6 | integrin, alpha 6 | 0.0224482 |
| ANXA5 | annexin A5 | 0.0223381 |
| ATP13A3 | ATPase type 13A3 | 0.0223217 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0222296 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0221975 |
| ACTN1 | actinin, alpha 1 | 0.0221829 |
| NUP58 | nucleoporin 58 | 0.0219964 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.021956 |
| PRELID2 | PRELI domain containing 2 | 0.0215958 |
| TFRC | transferrin receptor | 0.0215425 |
| ACTG1 | actin gamma 1 | 0.0215197 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0211971 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0211344 |
| HM13 | histocompatibility (minor) 13 | 0.0211186 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.020921 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0209128 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0208887 |
| SEC24A | SEC24 family member A | 0.0206191 |
| GPATCH2L | G patch domain containing 2-like | 0.0206085 |
| MAP1B | microtubule-associated protein 1B | 0.020601 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0205938 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0204619 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0203869 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0202591 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0202183 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0201631 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0201165 |
| AREG | amphiregulin | 0.020052 |
| FMNL2 | formin-like 2 | 0.0199401 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.0198543 |
| HPCAL1 | hippocalcin-like 1 | 0.0196581 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.01965 |
| ELOVL7 | ELOVL fatty acid elongase 7 | 0.0196441 |
| GTDC1 | glycosyltransferase-like domain containing 1 | 0.0195973 |
| FN1 | fibronectin 1 | 0.0195229 |
| EGR1 | early growth response 1 | 0.0195155 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.146149 |
| VIM | vimentin | -0.131893 |
| GNAS | GNAS complex locus | -0.0793779 |
| PTMA | prothymosin, alpha | -0.0679817 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0597169 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0494944 |
| TXNRD1 | thioredoxin reductase 1 | -0.0487871 |
| ANXA2 | annexin A2 | -0.0445086 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.044081 |
| CANX | calnexin | -0.0413033 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0409239 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0383072 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0378132 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0358202 |
| RPLP0 | ribosomal protein, large, P0 | -0.0356537 |
| NCOA6 | nuclear receptor coactivator 6 | -0.0340163 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0330979 |
| BSG | basigin (Ok blood group) | -0.0330413 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0328491 |
| SMYD3 | SET and MYND domain containing 3 | -0.0325409 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0321794 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0321667 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0316318 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0313961 |
| RPS23 | ribosomal protein S23 | -0.0305179 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0302392 |
| TMSB10 | thymosin beta 10 | -0.0302146 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.030051 |
| RPL32 | ribosomal protein L32 | -0.0299798 |
| DEK | DEK proto-oncogene | -0.0292865 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0292478 |
| NF1 | neurofibromin 1 | -0.0291346 |
| TPX2 | TPX2, microtubule-associated | -0.0281971 |
| SEPTIN7 | septin 7 | -0.0281588 |
| RPL4 | ribosomal protein L4 | -0.0279542 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0269614 |
| KIF5B | kinesin family member 5B | -0.0269249 |
| YBX3 | Y box binding protein 3 | -0.0268405 |
| GOLT1B | golgi transport 1B | -0.0265308 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0264323 |
| ANLN | anillin, actin binding protein | -0.0262152 |
| SPAG9 | sperm associated antigen 9 | -0.0258099 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0258029 |
| RPL12 | ribosomal protein L12 | -0.0256716 |
| ZNF609 | zinc finger protein 609 | -0.0256462 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0255892 |
| CENPF | centromere protein F, 350/400kDa | -0.0255749 |
| ECT2 | epithelial cell transforming 2 | -0.0255417 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.025371 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0250579 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0250569 |
| GLG1 | golgi glycoprotein 1 | -0.0249418 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0246702 |
| LATS2 | large tumor suppressor kinase 2 | -0.0245865 |
| EFNA5 | ephrin-A5 | -0.0244779 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0243469 |
| SSH2 | slingshot protein phosphatase 2 | -0.024203 |
| TUBB | tubulin, beta class I | -0.0236628 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0233882 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0233339 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0233326 |
| SGO2 | shugoshin 2 | -0.0232042 |
| KIAA1328 | KIAA1328 | -0.0231073 |
| TXNIP | thioredoxin interacting protein | -0.0230206 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0229411 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0226647 |
| RPL11 | ribosomal protein L11 | -0.0226624 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0224989 |
| TUT4 | terminal uridylyl transferase 4 | -0.0223393 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0222165 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0220253 |
| RPLP1 | ribosomal protein, large, P1 | -0.0220251 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0218677 |
| RPL34 | ribosomal protein L34 | -0.0216615 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0215366 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | -0.0214893 |
| HMGB1 | high mobility group box 1 | -0.0214675 |
| OGA | O-GlcNAcase | -0.021341 |
| TPM4 | tropomyosin 4 | -0.0212847 |
| PRR11 | proline rich 11 | -0.0211072 |
| TCF12 | transcription factor 12 | -0.0210853 |
| ETV6 | ets variant 6 | -0.0210725 |
| MATR3 | matrin 3 | -0.0208499 |
| CAPN7 | calpain 7 | -0.0208463 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0207796 |
| CFH | complement factor H | -0.0207583 |
| TCERG1 | transcription elongation regulator 1 | -0.0206794 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0206594 |
| NKTR | natural killer cell triggering receptor | -0.0204377 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.0203508 |
| ATM | ATM serine/threonine kinase | -0.0202259 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0200048 |
| RPS8 | ribosomal protein S8 | -0.0199814 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0199329 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0197036 |
| PHIP | pleckstrin homology domain interacting protein | -0.0196291 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0196014 |
| UBB | ubiquitin B | -0.019546 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0194942 |
| ZC3H6 | zinc finger CCCH-type containing 6 | -0.0194179 |
