| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | platelet factor 4|This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum. [provided by RefSeq, Oct 2014] (NCBI Entrez Gene Database, 5196) |
| External Link | https://ncbi.nlm.nih.gov/gene/5196 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the PF4 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GNAS | GNAS complex locus | 0.0183874 |
| XIC | X chromosome inactivation center | 0.0163481 |
| ABHD4 | abhydrolase domain containing 4 | 0.0150233 |
| EPCAM | epithelial cell adhesion molecule | 0.0142433 |
| ASPN | asporin | 0.0139483 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0137991 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.0131666 |
| MMP7 | matrix metallopeptidase 7 | 0.0120319 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.0116569 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.0112408 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0110665 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.0106262 |
| MFAP5 | microfibrillar associated protein 5 | 0.0105741 |
| LUM | lumican | 0.0104748 |
| OLFM4 | olfactomedin 4 | 0.0104507 |
| PERP | PERP, TP53 apoptosis effector | 0.0102918 |
| CTSK | cathepsin K | 0.0102582 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0101587 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.0100842 |
| KRT18 | keratin 18, type I | 0.00995805 |
| KRT19 | keratin 19, type I | 0.00973911 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00957916 |
| CLTB | clathrin, light chain B | 0.00955753 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00953814 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00930803 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00927626 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00913607 |
| TOB1 | transducer of ERBB2, 1 | 0.00906384 |
| DSP | desmoplakin | 0.00906178 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00898793 |
| SIK1 | salt-inducible kinase 1 | 0.00898673 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00882746 |
| KRT8 | keratin 8, type II | 0.00846495 |
| DCHS1 | dachsous cadherin-related 1 | 0.00844699 |
| COMP | cartilage oligomeric matrix protein | 0.00843103 |
| S100A10 | S100 calcium binding protein A10 | 0.00839171 |
| COL5A2 | collagen, type V, alpha 2 | 0.00835249 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.0083135 |
| ECM1 | extracellular matrix protein 1 | 0.00827672 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00825699 |
| ATF3 | activating transcription factor 3 | 0.00825498 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.00819368 |
| BBX | bobby sox homolog (Drosophila) | 0.00814962 |
| TPD52 | tumor protein D52 | 0.00814612 |
| RIPOR2 | RHO family interacting cell polarization regulator 2 | 0.00810089 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00802947 |
| LPAR6 | lysophosphatidic acid receptor 6 | 0.00801963 |
| PLAT | plasminogen activator, tissue | 0.00796513 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 0.0079589 |
| MERTK | MER proto-oncogene, tyrosine kinase | 0.00792044 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00789296 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 0.00784727 |
| TGIF1 | TGFB-induced factor homeobox 1 | 0.00774289 |
| COL10A1 | collagen, type X, alpha 1 | 0.00767861 |
| TGFA | transforming growth factor, alpha | 0.00765893 |
| CHP1 | calcineurin-like EF-hand protein 1 | 0.00760252 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00756661 |
| SERINC5 | serine incorporator 5 | 0.00756582 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00753927 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00751664 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.00751223 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00750888 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00750553 |
| HLA-B | major histocompatibility complex, class I, B | 0.00749299 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00747628 |
| CADM1 | cell adhesion molecule 1 | 0.00746471 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00744024 |
| CIDEC | cell death-inducing DFFA-like effector c | 0.00743782 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.0074136 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.00738303 |
| VGLL4 | vestigial-like family member 4 | 0.00737006 |
| NPC2 | Niemann-Pick disease, type C2 | 0.00736297 |
| GSN | gelsolin | 0.00734692 |
| TXNIP | thioredoxin interacting protein | 0.00733486 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00732507 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.00730961 |
| ITGAV | integrin, alpha V | 0.0072914 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00728471 |
| MFGE8 | milk fat globule-EGF factor 8 protein | 0.00728185 |
| MIR22HG | MIR22 host gene | 0.00725526 |
| AGR2 | anterior gradient 2 | 0.00723652 |
| GLS | glutaminase | 0.0072226 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.00722193 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.00721307 |
| CHRDL1 | chordin-like 1 | 0.00719286 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | 0.00718482 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00717685 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00715757 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00714748 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0071323 |
| CDCA4 | cell division cycle associated 4 | 0.00712706 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.00711197 |
| CTSE | cathepsin E | 0.00706381 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | 0.00698889 |
| MX2 | MX dynamin-like GTPase 2 | 0.00690889 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00690777 |
| LAMC2 | laminin, gamma 2 | 0.00689646 |
| POSTN | periostin, osteoblast specific factor | 0.00685982 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 | 0.00682527 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00677393 |
| THBS2 | thrombospondin 2 | 0.00674802 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 | 0.00671049 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00669655 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00661799 |
| CD9 | CD9 molecule | 0.00660621 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.0065967 |
| JUP | junction plakoglobin | 0.00658544 |
| PLLP | plasmolipin | 0.00657476 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.00652949 |
| IL1R1 | interleukin 1 receptor, type I | 0.00652264 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00652135 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.00648332 |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled | 0.00647735 |
| PLS3 | plastin 3 | 0.00647313 |
| LEPROT | leptin receptor overlapping transcript | 0.00646367 |
| BMP2 | bone morphogenetic protein 2 | 0.00643999 |
| LXN | latexin | 0.00643275 |
| IRS2 | insulin receptor substrate 2 | 0.00643048 |
| TSPAN13 | tetraspanin 13 | 0.00641371 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.00639902 |
| REG1A | regenerating islet-derived 1 alpha | 0.00636549 |
| GPX2 | glutathione peroxidase 2 | 0.00636176 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00635554 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00631931 |
| PTER | phosphotriesterase related | 0.00631401 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.00631191 |
| TBX3 | T-box 3 | 0.00630414 |
| EPYC | epiphycan | 0.0062952 |
| CLDN3 | claudin 3 | 0.00629447 |
| LPIN1 | lipin 1 | 0.0062305 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 | 0.00622184 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 | 0.00621514 |
| TLR4 | toll-like receptor 4 | 0.00620822 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.00620452 |
| REG1B | regenerating islet-derived 1 beta | 0.00617559 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 | 0.00617339 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | 0.00616093 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 0.00611821 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 0.00611138 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.00610785 |
| MYO6 | myosin VI | 0.00610243 |
| BTG2 | BTG family, member 2 | 0.00609861 |
| MMP11 | matrix metallopeptidase 11 | 0.00606516 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.00606218 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.00605041 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.00604131 |
| CTSV | cathepsin V | 0.00601879 |
| AOC3 | amine oxidase, copper containing 3 | 0.00600874 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 | 0.00600652 |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 | 0.00599585 |
| ACVR1 | activin A receptor, type I | 0.00597665 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0059556 |
| SMAD7 | SMAD family member 7 | 0.00593317 |
| SPP1 | secreted phosphoprotein 1 | 0.00593064 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.00586913 |
| OAT | ornithine aminotransferase | 0.00586816 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.00586723 |
| NR0B1 | nuclear receptor subfamily 0, group B, member 1 | 0.00585111 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.00584922 |
| SC5D | sterol-C5-desaturase | 0.00580489 |
| TRIM38 | tripartite motif containing 38 | 0.00578907 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | 0.00578877 |
| TEX10 | testis expressed 10 | 0.00577484 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | 0.00577236 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | 0.00575309 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | 0.00574352 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.00570549 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00570308 |
| NPY1R | neuropeptide Y receptor Y1 | 0.00567468 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00566731 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.00566158 |
| RPS27L | ribosomal protein S27-like | 0.00563146 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 0.00562387 |
| GAS7 | growth arrest-specific 7 | 0.0056184 |
| AVPI1 | arginine vasopressin-induced 1 | 0.00561161 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00561044 |
| REG3A | regenerating islet-derived 3 alpha | 0.00560619 |
| FAM13B | family with sequence similarity 13, member B | 0.00560069 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00559708 |
| ANXA4 | annexin A4 | 0.00559665 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.00558623 |
| CHMP4A | charged multivesicular body protein 4A | 0.00555891 |
| APOB | apolipoprotein B | 0.0055383 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.00553295 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | 0.00552075 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | 0.00551654 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0055029 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00549429 |
| HLA-C | major histocompatibility complex, class I, C | 0.0054928 |
| HLA-F | major histocompatibility complex, class I, F | 0.00548801 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00547045 |
| UPP1 | uridine phosphorylase 1 | 0.00545325 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00544603 |
| KDSR | 3-ketodihydrosphingosine reductase | 0.00544254 |
| INHBA | inhibin, beta A | 0.00544121 |
| GSTP1 | glutathione S-transferase pi 1 | 0.00544018 |
| NKX2-1 | NK2 homeobox 1 | 0.00543728 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.00543345 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00543294 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 0.0054276 |
| NUTF2 | nuclear transport factor 2 | 0.00542655 |
| PON2 | paraoxonase 2 | 0.00542635 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta | 0.00541864 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 | 0.00540777 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00537921 |
| PROM1 | prominin 1 | 0.0053673 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.00536641 |
| EGFL6 | EGF-like-domain, multiple 6 | 0.00535943 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.00535028 |
| MXRA5 | matrix-remodelling associated 5 | 0.00534187 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.00533329 |
| BTG3 | BTG family, member 3 | 0.00533274 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00533096 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0053282 |
| HLA-A | major histocompatibility complex, class I, A | 0.00531955 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.00531884 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00531089 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.00530985 |
| SCPEP1 | serine carboxypeptidase 1 | 0.00530366 |
| ANXA1 | annexin A1 | 0.00529883 |
| MITF | microphthalmia-associated transcription factor | 0.00528778 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00526342 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.00525785 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0052575 |
| ITGB4 | integrin, beta 4 | 0.00525691 |
| C3 | complement component 3 | 0.0052568 |
| HEPH | hephaestin | 0.00525416 |
| CBFB | core-binding factor, beta subunit | 0.00523901 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | 0.00523333 |
| MTF2 | metal response element binding transcription factor 2 | 0.00521355 |
| PHYH | phytanoyl-CoA 2-hydroxylase | 0.00518871 |
| KRT7 | keratin 7, type II | 0.00518821 |
| FNTA | farnesyltransferase, CAAX box, alpha | 0.00518643 |
| DSG2 | desmoglein 2 | 0.00518562 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.00517782 |
| FABP1 | fatty acid binding protein 1, liver | 0.00516318 |
| PLAU | plasminogen activator, urokinase | 0.00516183 |
| VPS35 | vacuolar protein sorting 35 homolog (S. cerevisiae) | 0.00513948 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.00513851 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | 0.00513614 |
| SNAI2 | snail family zinc finger 2 | 0.00512746 |
| ZG16 | zymogen granule protein 16 | 0.00511323 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00511321 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | 0.0051123 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | 0.00511184 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | 0.00510073 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0050986 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase | 0.00508371 |
| TP53I3 | tumor protein p53 inducible protein 3 | 0.0050725 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0279482 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.0139977 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.0134893 |
| CA12 | carbonic anhydrase XII | -0.0130858 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.0127501 |
| CA2 | carbonic anhydrase II | -0.0117732 |
| TMSB15A | thymosin beta 15a | -0.0106998 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -0.0105924 |
| RTN2 | reticulon 2 | -0.0105798 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.0091405 |
| S100A7 | S100 calcium binding protein A7 | -0.00903078 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00901979 |
| MEIS2 | Meis homeobox 2 | -0.00895773 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.00888125 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.0088448 |
| RGCC | regulator of cell cycle | -0.00852342 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00850722 |
| GLUL | glutamate-ammonia ligase | -0.0084869 |
| FLNC | filamin C, gamma | -0.00843287 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | -0.00834588 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.00818653 |
| NREP | neuronal regeneration related protein | -0.00814466 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00808302 |
| PTN | pleiotrophin | -0.00801585 |
| STMN2 | stathmin 2 | -0.00789017 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00783314 |
| HBB | hemoglobin, beta | -0.00782518 |
| PRC1 | protein regulator of cytokinesis 1 | -0.00780731 |
| OLFM1 | olfactomedin 1 | -0.0076834 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | -0.00761432 |
| EREG | epiregulin | -0.00740869 |
| NEFM | neurofilament, medium polypeptide | -0.00736094 |
| LIG1 | ligase I, DNA, ATP-dependent | -0.00733008 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00722244 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.00719098 |
| CLU | clusterin | -0.00708932 |
| PENK | proenkephalin | -0.00699758 |
| KIF20A | kinesin family member 20A | -0.00699519 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00695644 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00695534 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.00694995 |
| FASN | fatty acid synthase | -0.00691954 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00690502 |
| NES | nestin | -0.00689729 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0068803 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | -0.00682714 |
| TTC39A | tetratricopeptide repeat domain 39A | -0.00678779 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.00676254 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00671775 |
| TTN | titin | -0.00665881 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.00657452 |
| ARG1 | arginase 1 | -0.00650638 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.00650413 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00649995 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00647144 |
| ANGPT2 | angiopoietin 2 | -0.00646103 |
| CA9 | carbonic anhydrase IX | -0.00636152 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | -0.00633704 |
| SETBP1 | SET binding protein 1 | -0.00633192 |
| SNCAIP | synuclein, alpha interacting protein | -0.00629455 |
| S100A9 | S100 calcium binding protein A9 | -0.00619806 |
| CALML5 | calmodulin-like 5 | -0.00619408 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00618759 |
| CALB1 | calbindin 1, 28kDa | -0.00614537 |
| STC2 | stanniocalcin 2 | -0.00614236 |
| SRGN | serglycin | -0.00612684 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.00603317 |
| DBF4 | DBF4 zinc finger | -0.0060272 |
| TSPAN5 | tetraspanin 5 | -0.00600824 |
| KLHDC8A | kelch domain containing 8A | -0.00597142 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.00597114 |
| PEG10 | paternally expressed 10 | -0.00595998 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -0.00592064 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | -0.00591701 |
| DAXX | death-domain associated protein | -0.00587106 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | -0.00581905 |
| MAPT | microtubule-associated protein tau | -0.00579569 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.0057864 |
| GPM6A | glycoprotein M6A | -0.00577264 |
| FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23) | -0.00571909 |
| DCLK1 | doublecortin-like kinase 1 | -0.0057106 |
| CCNA2 | cyclin A2 | -0.0057003 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.00569216 |
| FAM107A | family with sequence similarity 107, member A | -0.00569055 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.00568917 |
| TRIB3 | tribbles pseudokinase 3 | -0.00568521 |
| HAL | histidine ammonia-lyase | -0.00567244 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.00565119 |
| MYBPC1 | myosin binding protein C, slow type | -0.00563008 |
| UPB1 | ureidopropionase, beta | -0.00562653 |
| RET | ret proto-oncogene | -0.00560642 |
| LY6D | lymphocyte antigen 6 complex, locus D | -0.00558972 |
| RNH1 | ribonuclease/angiogenin inhibitor 1 | -0.00558483 |
| KRT1 | keratin 1, type II | -0.00557159 |
| PBK | PDZ binding kinase | -0.00556444 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.00554682 |
| SRP72 | signal recognition particle 72kDa | -0.00554596 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | -0.00553604 |
| PLEK | pleckstrin | -0.0055215 |
| EPHB2 | EPH receptor B2 | -0.0055121 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 | -0.00549691 |
| BEX1 | brain expressed, X-linked 1 | -0.00547619 |
| C7 | complement component 7 | -0.00546185 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | -0.00546116 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.00545942 |
| MKI67 | marker of proliferation Ki-67 | -0.00544572 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00541593 |
| GUCY2C | guanylate cyclase 2C | -0.00540774 |
| PCLAF | PCNA clamp associated factor | -0.00540234 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.00539038 |
| PEX6 | peroxisomal biogenesis factor 6 | -0.0053828 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.00526083 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00525364 |
| HBD | hemoglobin, delta | -0.00520938 |
| GAP43 | growth associated protein 43 | -0.00520882 |
| VSNL1 | visinin-like 1 | -0.00520199 |
| SELENBP1 | selenium binding protein 1 | -0.00520003 |
| MEIS1 | Meis homeobox 1 | -0.00516081 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.0051597 |
| HSPA4L | heat shock 70kDa protein 4-like | -0.00515461 |
| SELENOW | selenoprotein W | -0.00515024 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.00514617 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00514096 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.00513175 |
| HOXB6 | homeobox B6 | -0.00512079 |
| PRR16 | proline rich 16 | -0.00511724 |
| VWF | von Willebrand factor | -0.00510641 |
| RHOB | ras homolog family member B | -0.00510395 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.00509574 |
| NAV3 | neuron navigator 3 | -0.00508383 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.00507731 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.00506337 |
| FANCG | Fanconi anemia, complementation group G | -0.00504864 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | -0.00504602 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | -0.00504576 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.00502575 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.00502235 |
| RGS3 | regulator of G-protein signaling 3 | -0.00500968 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -0.00500493 |
| AUTS2 | autism susceptibility candidate 2 | -0.00499679 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -0.00499206 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00498425 |
| ANXA6 | annexin A6 | -0.00497554 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0049721 |
| PF4 | platelet factor 4 | -0.00497139 |
| GPR88 | G protein-coupled receptor 88 | -0.00496282 |
| FBL | fibrillarin | -0.00496275 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | -0.00496107 |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | -0.00495867 |
| NOD2 | nucleotide-binding oligomerization domain containing 2 | -0.00495849 |
| CNTNAP2 | contactin associated protein-like 2 | -0.00495295 |
| BNC2 | basonuclin 2 | -0.00494621 |
| NKG7 | natural killer cell granule protein 7 | -0.00493262 |
| CIT | citron rho-interacting serine/threonine kinase | -0.00492432 |
| TNNI1 | troponin I type 1 (skeletal, slow) | -0.00492267 |
| GAL | galanin/GMAP prepropeptide | -0.00491091 |
| STEAP1B | STEAP family member 1B | -0.0048995 |
| COPS6 | COP9 signalosome subunit 6 | -0.00489182 |
| OBSL1 | obscurin-like 1 | -0.00488978 |
| RACGAP1 | Rac GTPase activating protein 1 | -0.00488745 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase | -0.00488687 |
| LOR | loricrin | -0.00488056 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00487761 |
| TPX2 | TPX2, microtubule-associated | -0.004863 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | -0.00486283 |
| XCL1 | chemokine (C motif) ligand 1 | -0.00486139 |
| MRPS27 | mitochondrial ribosomal protein S27 | -0.00483949 |
| TNC | tenascin C | -0.00483884 |
| MCM5 | minichromosome maintenance complex component 5 | -0.00483098 |
| MNDA | myeloid cell nuclear differentiation antigen | -0.00482896 |
| MEG3 | maternally expressed 3 (non-protein coding) | -0.00482092 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.0048138 |
| DOP1B | DOP1 leucine zipper like protein B | -0.00481073 |
| CDHR1 | cadherin-related family member 1 | -0.00480375 |
| KIF11 | kinesin family member 11 | -0.0047883 |
| CDC25B | cell division cycle 25B | -0.00478709 |
| DMAC2 | distal membrane arm assembly component 2 | -0.00478155 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | -0.00477873 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00475729 |
| POLR3B | polymerase (RNA) III (DNA directed) polypeptide B | -0.00473648 |
| TMEM176B | transmembrane protein 176B | -0.00472872 |
| THSD7A | thrombospondin, type I, domain containing 7A | -0.00469319 |
| SOX11 | SRY (sex determining region Y)-box 11 | -0.00468661 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.00468529 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | -0.00465474 |
| NCAPG | non-SMC condensin I complex, subunit G | -0.00465453 |
| HMGB2 | high mobility group box 2 | -0.00465022 |
| KLHL41 | kelch-like family member 41 | -0.0046481 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | -0.00464659 |
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 | -0.00464329 |
| AMMECR1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 | -0.00462481 |
| CD248 | CD248 molecule, endosialin | -0.00462452 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | -0.00460856 |
| TFR2 | transferrin receptor 2 | -0.00460611 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.004604 |
| SOBP | sine oculis binding protein homolog (Drosophila) | -0.00460236 |
| PLXNA2 | plexin A2 | -0.0045918 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.00459157 |
| MED22 | mediator complex subunit 22 | -0.00458862 |
| SNRPA | small nuclear ribonucleoprotein polypeptide A | -0.00456279 |
| RTN1 | reticulon 1 | -0.00455939 |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) | -0.00454977 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.00454872 |
| VEGFA | vascular endothelial growth factor A | -0.00454657 |
| MYL6B | myosin, light chain 6B, alkali, smooth muscle and non-muscle | -0.00454039 |
| CST7 | cystatin F (leukocystatin) | -0.00453534 |
| H2AFV | H2A histone family, member V | -0.00451574 |
| KIF23 | kinesin family member 23 | -0.00451405 |
| ASMTL | acetylserotonin O-methyltransferase-like | -0.00451323 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00451253 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00450387 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | -0.00450155 |
| AQP5 | aquaporin 5 | -0.00450021 |
| TEAD4 | TEA domain family member 4 | -0.0045002 |
| INHBB | inhibin, beta B | -0.00449861 |
| C12ORF29 | chromosome 12 open reading frame 29 | -0.00449424 |
| PI4KA | phosphatidylinositol 4-kinase, catalytic, alpha | -0.00448232 |
| TMEM176A | transmembrane protein 176A | -0.00447988 |
| ZNF22 | zinc finger protein 22 | -0.00447956 |
| COLEC11 | collectin sub-family member 11 | -0.00447798 |
| ESM1 | endothelial cell-specific molecule 1 | -0.00446043 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -0.00445766 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.00444786 |
| ZFHX4 | zinc finger homeobox 4 | -0.00444666 |
| MCM6 | minichromosome maintenance complex component 6 | -0.0044448 |
| NDRG2 | NDRG family member 2 | -0.00444341 |
| TRMT5 | tRNA methyltransferase 5 | -0.00444183 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.00444072 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00443672 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.00443055 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | -0.00442617 |
| TBL1X | transducin (beta)-like 1X-linked | -0.00441878 |
| CSK | c-src tyrosine kinase | -0.00440446 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | -0.0044009 |
| AGTR1 | angiotensin II receptor, type 1 | -0.00439808 |
| YEATS4 | YEATS domain containing 4 | -0.0043816 |
| ANXA10 | annexin A10 | -0.0043807 |
| NNAT | neuronatin | -0.00437582 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.0043756 |
| PRPF8 | pre-mRNA processing factor 8 | -0.00436069 |
| LIMA1 | LIM domain and actin binding 1 | -0.00436001 |
| LMNB2 | lamin B2 | -0.00435566 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | -0.00435565 |
| RRM2 | ribonucleotide reductase M2 | -0.00434985 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00434062 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | -0.00434059 |
| MID1IP1 | MID1 interacting protein 1 | -0.00433515 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | -0.00433272 |
| PITX2 | paired-like homeodomain 2 | -0.00433066 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | -0.00433032 |
