PFSK-1 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: malignant primitive neuroectodermal tumor (Cell Line Ontology, CLO_0008425)
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Genes

216 genes mutated in the PFSK-1 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACSM5 acyl-CoA synthetase medium-chain family member 5
ADAM32 ADAM metallopeptidase domain 32
ADAMTSL2 ADAMTS-like 2
ADAMTSL4 ADAMTS-like 4
ADGRF2 adhesion G protein-coupled receptor F2
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
AGBL4 ATP/GTP binding protein-like 4
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2
AIM1 absent in melanoma 1
AIRE autoimmune regulator
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B
ANO3 anoctamin 3
APOBEC3H apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
APOLD1 apolipoprotein L domain containing 1
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATOH8 atonal homolog 8 (Drosophila)
ATP10B ATPase, class V, type 10B
ATP9B ATPase, class II, type 9B
ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1
BAAT bile acid CoA:amino acid N-acyltransferase
BANF2 barrier to autointegration factor 2
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
BCL2L1 BCL2-like 1
BFSP1 beaded filament structural protein 1, filensin
BLM Bloom syndrome, RecQ helicase-like
BLVRA biliverdin reductase A
CA9 carbonic anhydrase IX
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CC2D1A coiled-coil and C2 domain containing 1A
CCDC116 coiled-coil domain containing 116
CD1A CD1a molecule
CD247 CD247 molecule
CDC42BPG CDC42 binding protein kinase gamma (DMPK-like)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21
CENPJ centromere protein J
CFAP97 cilia and flagella associated protein 97
CHRM3 cholinergic receptor, muscarinic 3
CHSY3 chondroitin sulfate synthase 3
CIB4 calcium and integrin binding family member 4
CIDEC cell death-inducing DFFA-like effector c
CLP1 cleavage and polyadenylation factor I subunit 1
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CNTLN centlein, centrosomal protein
COL6A2 collagen, type VI, alpha 2
CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CROCC ciliary rootlet coiled-coil, rootletin
CTNND1 catenin (cadherin-associated protein), delta 1
CTSF cathepsin F
CYFIP2 cytoplasmic FMR1 interacting protein 2
DACT2 dishevelled-binding antagonist of beta-catenin 2
DAPK2 death-associated protein kinase 2
DCHS1 dachsous cadherin-related 1
DDIT4 DNA-damage-inducible transcript 4
DDX12P DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12, pseudogene
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DMXL1 Dmx-like 1
DNAH11 dynein, axonemal, heavy chain 11
DNAH2 dynein, axonemal, heavy chain 2
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DOPEY2 dopey family member 2
DSE dermatan sulfate epimerase
DST dystonin
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EDC4 enhancer of mRNA decapping 4
EHD4 EH-domain containing 4
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EML3 echinoderm microtubule associated protein like 3
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
F8 coagulation factor VIII, procoagulant component
FAM110C family with sequence similarity 110, member C
FAM9B family with sequence similarity 9, member B
FAT4 FAT atypical cadherin 4
FBN1 fibrillin 1
FGF20 fibroblast growth factor 20
FIGNL1 fidgetin-like 1
FLG filaggrin
FLNB filamin B, beta
FN1 fibronectin 1
FOCAD focadhesin
FOXN1 forkhead box N1
FRZB frizzled-related protein
GCNT7 glucosaminyl (N-acetyl) transferase family member 7
GDF2 growth differentiation factor 2
GGCX gamma-glutamyl carboxylase
GLI3 GLI family zinc finger 3
GLT6D1 glycosyltransferase 6 domain containing 1
GMPR guanosine monophosphate reductase
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GRIK1 glutamate receptor, ionotropic, kainate 1
GSN gelsolin
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BJ histone cluster 1, H2bj
HIST3H2BB histone cluster 3, H2bb
HLA-C major histocompatibility complex, class I, C
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HYDIN HYDIN, axonemal central pair apparatus protein
IGFBP7 insulin-like growth factor binding protein 7
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL1F10 interleukin 1 family, member 10 (theta)
IL20RA interleukin 20 receptor, alpha
IMPAD1 inositol monophosphatase domain containing 1
INADL InaD-like (Drosophila)
IPO9 importin 9
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA0754 KIAA0754
KLK2 kallikrein-related peptidase 2
KRT37 keratin 37, type I
LHX4 LIM homeobox 4
LMOD3 leiomodin 3 (fetal)
LONRF1 LON peptidase N-terminal domain and ring finger 1
LONRF2 LON peptidase N-terminal domain and ring finger 2
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MED13L mediator complex subunit 13-like
MON2 MON2 homolog (S. cerevisiae)
MUC4 mucin 4, cell surface associated
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
NBAS neuroblastoma amplified sequence
NCOA7 nuclear receptor coactivator 7
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
NECAB1 N-terminal EF-hand calcium binding protein 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFE2L3 nuclear factor, erythroid 2-like 3
NUP98 nucleoporin 98kDa
OR10G9 olfactory receptor, family 10, subfamily G, member 9
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCDH11X protocadherin 11 X-linked
PCDHA7 protocadherin alpha 7
PDE4DIP phosphodiesterase 4D interacting protein
PFAS phosphoribosylformylglycinamidine synthase
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLS1 plastin 1
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
PRAMEF10 PRAME family member 10
PSME4 proteasome (prosome, macropain) activator subunit 4
PTCH2 patched 2
PTPRD protein tyrosine phosphatase, receptor type, D
PTPRS protein tyrosine phosphatase, receptor type, S
RAB28 RAB28, member RAS oncogene family
RBBP4 retinoblastoma binding protein 4
RBM12B RNA binding motif protein 12B
RBM44 RNA binding motif protein 44
REEP2 receptor accessory protein 2
RGS20 regulator of G-protein signaling 20
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RP1L1 retinitis pigmentosa 1-like 1
RPA1 replication protein A1, 70kDa
RSPO2 R-spondin 2
RUMY1 regulator of UNG2 and MKLN1 interacting yippee protein 1
SCAF1 SR-related CTD-associated factor 1
SCN3A sodium channel, voltage gated, type III alpha subunit
SELENBP1 selenium binding protein 1
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
SEMG1 semenogelin I
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SGK3 serum/glucocorticoid regulated kinase family, member 3
SIGLEC5 sialic acid binding Ig-like lectin 5
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLC6A16 solute carrier family 6, member 16
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMC4 structural maintenance of chromosomes 4
SMYD4 SET and MYND domain containing 4
SOS1 son of sevenless homolog 1 (Drosophila)
SOX13 SRY (sex determining region Y)-box 13
SP100 SP100 nuclear antigen
SPOCD1 SPOC domain containing 1
SPTA1 spectrin, alpha, erythrocytic 1
SYTL2 synaptotagmin-like 2
TAS2R31 taste receptor, type 2, member 31
TBC1D2B TBC1 domain family, member 2B
TGFBR3 transforming growth factor, beta receptor III
TLK2 tousled-like kinase 2
TM2D1 TM2 domain containing 1
TM9SF2 transmembrane 9 superfamily member 2
TMEM161B transmembrane protein 161B
TMEM173 transmembrane protein 173
TMEM214 transmembrane protein 214
TMTC2 transmembrane and tetratricopeptide repeat containing 2
TNPO2 transportin 2
TP53 tumor protein p53
TPBG trophoblast glycoprotein
TPH2 tryptophan hydroxylase 2
TRIM74 tripartite motif containing 74
TSC2 tuberous sclerosis 2
TTC37 tetratricopeptide repeat domain 37
TUBGCP3 tubulin, gamma complex associated protein 3
TUBGCP6 tubulin, gamma complex associated protein 6
UBA7 ubiquitin-like modifier activating enzyme 7
USP19 ubiquitin specific peptidase 19
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae)
WEE1 WEE1 G2 checkpoint kinase
WFS1 Wolfram syndrome 1 (wolframin)
WHSC1 Wolf-Hirschhorn syndrome candidate 1
WISP2 WNT1 inducible signaling pathway protein 2
XBP1 X-box binding protein 1
ZNF121 zinc finger protein 121
ZNF136 zinc finger protein 136
ZNF292 zinc finger protein 292
ZNF513 zinc finger protein 513
ZNF530 zinc finger protein 530
ZNF610 zinc finger protein 610
ZNF708 zinc finger protein 708
ZNF709 zinc finger protein 709
ZNF784 zinc finger protein 784
ZNF786 zinc finger protein 786