PGAM5 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description phosphoglycerate mutase family member 5| (NCBI Entrez Gene Database, 192111)
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Genes

325 genes differentially expressed following the PGAM5 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
GJA9 gap junction protein, alpha 9, 59kDa 2.87612
SCNN1D sodium channel, non voltage gated 1 delta subunit 2.87612
RHOJ ras homolog family member J 2.87612
AMPD1 adenosine monophosphate deaminase 1 2.87612
LRRK2 leucine-rich repeat kinase 2 2.87612
GJB3 gap junction protein, beta 3, 31kDa 2.87612
SCRG1 stimulator of chondrogenesis 1 2.87612
PADI1 peptidyl arginine deiminase, type I 2.87612
TMEM82 transmembrane protein 82 2.87612
CCDC27 coiled-coil domain containing 27 2.87612
HES3 hes family bHLH transcription factor 3 2.87612
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 2.87612
SCRT2 scratch family zinc finger 2 2.87612
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2 2.87612
OR10AG1 olfactory receptor, family 10, subfamily AG, member 1 2.87612
RP1L1 retinitis pigmentosa 1-like 1 2.87612
ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 2.87612
NFAM1 NFAT activating protein with ITAM motif 1 2.87612
NEU4 sialidase 4 2.87612
GPR149 G protein-coupled receptor 149 2.87612
ASMT acetylserotonin O-methyltransferase 2.87612
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 2.87612
H2BC12 H2B clustered histone 12 2.87612
AVPR1B arginine vasopressin receptor 1B 2.87612
STX11 syntaxin 11 2.87612
PDZRN4 PDZ domain containing ring finger 4 2.87612
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 2.82824
RGPD4 RANBP2-like and GRIP domain containing 4 2.82824
VTN vitronectin 2.82824
PRICKLE4 prickle homolog 4 (Drosophila) 2.82824
OR52A5 olfactory receptor, family 52, subfamily A, member 5 2.82824
CD14 CD14 molecule 2.82824
ZBTB42 zinc finger and BTB domain containing 42 2.82824
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 2.82824
CTRC chymotrypsin C (caldecrin) 2.82824
CX3CR1 chemokine (C-X3-C motif) receptor 1 2.82824
PARP3 poly (ADP-ribose) polymerase family, member 3 2.82824
OR2AG2 olfactory receptor, family 2, subfamily AG, member 2 2.82824
CDH5 cadherin 5, type 2 (vascular endothelium) 2.82824
PLCH2 phospholipase C, eta 2 2.82824
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 2.82824
ZNF662 zinc finger protein 662 2.82824
GMFG glia maturation factor, gamma 2.82824
EPPIN epididymal peptidase inhibitor 2.82824
MSC musculin 2.82824
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 2.82824
DSG3 desmoglein 3 2.82824
SHCBP1L SHC SH2-domain binding protein 1-like 2.82824
CSTL1 cystatin-like 1 2.82824
GPR21 G protein-coupled receptor 21 2.82824
ELSPBP1 epididymal sperm binding protein 1 2.82824
ADGB androglobin 2.82824
SGPP2 sphingosine-1-phosphate phosphatase 2 2.82824
OR10A4 olfactory receptor, family 10, subfamily A, member 4 2.82824
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 2.82824
CXCL2 chemokine (C-X-C motif) ligand 2 2.82824
KRT23 keratin 23, type I 2.82824
SLC35G5 solute carrier family 35, member G5 2.82824
TRPV6 transient receptor potential cation channel, subfamily V, member 6 2.82824
NUGGC nuclear GTPase, germinal center associated 2.82824
COL19A1 collagen, type XIX, alpha 1 2.82824
LOC107986837 uncharacterized LOC107986837 2.82824
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 2.82824
GPR37L1 G protein-coupled receptor 37 like 1 2.82824
LY6H lymphocyte antigen 6 complex, locus H 2.82824
CSAG1 chondrosarcoma associated gene 1 2.82824
GPR85 G protein-coupled receptor 85 2.82824
CFAP99 cilia and flagella associated protein 99 2.82824
ARMC12 armadillo repeat containing 12 2.82824
CAPN8 calpain 8 2.82824
C6 complement component 6 2.82824
OR6F1 olfactory receptor, family 6, subfamily F, member 1 2.82824
PLCZ1 phospholipase C, zeta 1 2.82824
FMOD fibromodulin 2.82824
CSNK2A2IP casein kinase 2 subunit alpha' interacting protein 2.82824
SPMIP11 sperm microtubule inner protein 11 2.82824
VCF1 VCP nuclear cofactor family member 1 2.82824
OOSP4A oocyte secreted protein family member 4A 2.82824
LOC124903233 uncharacterized LOC124903233 2.82824
H2BW2 H2B.W histone 2 2.82824
PLAAT4 phospholipase A and acyltransferase 4 2.82824
ASDURF ASNSD1 upstream open reading frame 2.82824
LTB4R2 leukotriene B4 receptor 2 2.82824
SASH3 SAM and SH3 domain containing 3 2.82824
SBSN suprabasin 2.82824
TUBA3D tubulin, alpha 3d 2.82824
ARL5C ADP-ribosylation factor-like 5C 2.82824
PRB4 proline-rich protein BstNI subfamily 4 2.82824
APOBEC4 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative) 2.82824
FAM3D family with sequence similarity 3, member D 2.82824
USH1G Usher syndrome 1G (autosomal recessive) 2.82824
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 2.82824
SLC22A14 solute carrier family 22, member 14 2.82824
SYCP2 synaptonemal complex protein 2 2.82824
CCDC13 coiled-coil domain containing 13 2.82824
EDAR ectodysplasin A receptor 2.82824
GHSR growth hormone secretagogue receptor 2.82824
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 2.82824
S100G S100 calcium binding protein G 2.82824
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 2.82824
CDSN corneodesmosin 2.82824
SPDYC speedy/RINGO cell cycle regulator family member C 2.82824
INSRR insulin receptor-related receptor 2.82824
TBX5 T-box 5 2.82824
TLR6 toll-like receptor 6 2.82824
HPR haptoglobin-related protein 2.82824
HNF4A hepatocyte nuclear factor 4, alpha 2.82824
OR3A1 olfactory receptor, family 3, subfamily A, member 1 2.82824
GLOD5 glyoxalase domain containing 5 2.82824
SMIM23 small integral membrane protein 23 2.82824
EMX2 empty spiracles homeobox 2 2.82824
WFDC6 WAP four-disulfide core domain 6 2.82824
WFDC9 WAP four-disulfide core domain 9 2.82824
CALHM3 calcium homeostasis modulator 3 2.82824
GLT1D1 glycosyltransferase 1 domain containing 1 2.82824
CLEC4G C-type lectin domain family 4, member G 2.82824
HUS1B HUS1 checkpoint homolog b (S. pombe) 2.82824
RSPH10B radial spoke head 10 homolog B (Chlamydomonas) 2.82824
LYG1 lysozyme G-like 1 2.82824
DQX1 DEAQ box RNA-dependent ATPase 1 2.82824
KRT17 keratin 17, type I 2.82824
TBPL2 TATA box binding protein like 2 2.82824
OR9Q1 olfactory receptor, family 9, subfamily Q, member 1 2.82824
FBXO39 F-box protein 39 2.82824
MYF6 myogenic factor 6 (herculin) 2.82824
MRLN myoregulin 2.82824
EDN3 endothelin 3 2.82824
CLDN34 claudin 34 2.82824
GOLGA8N golgin A8 family, member N 2.82824
HCRT hypocretin (orexin) neuropeptide precursor 2.82824
LMOD2 leiomodin 2 (cardiac) 2.82824
COX7B2 cytochrome c oxidase subunit VIIb2 2.82824
CDH17 cadherin 17, LI cadherin (liver-intestine) 2.82824
DLX3 distal-less homeobox 3 2.82824
HIGD2A HIG1 hypoxia inducible domain family, member 2A 2.82824
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 2.82824
IGIP IgA-inducing protein 2.82824
KLHL12 kelch-like family member 12 2.82824
GPR150 G protein-coupled receptor 150 2.82824
GPR142 G protein-coupled receptor 142 2.82824
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 2.82824
PLA2G2C phospholipase A2, group IIC 2.82824
GSTA2 glutathione S-transferase alpha 2 2.82824
LSMEM1 leucine-rich single-pass membrane protein 1 2.82824
VWA3B von Willebrand factor A domain containing 3B 2.82824
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C 2.82824
HRCT1 histidine rich carboxyl terminus 1 2.82824
ITGA8 integrin, alpha 8 2.82824
C8ORF89 chromosome 8 open reading frame 89 2.82824
FAM135B family with sequence similarity 135, member B 2.82824
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 2.82824
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 2.82824
ARL13A ADP-ribosylation factor-like 13A 2.82824
CRYBA1 crystallin, beta A1 2.82824
MB myoglobin 2.82824
PDCD1 programmed cell death 1 2.82824
C8ORF74 chromosome 8 open reading frame 74 2.82824
ANXA2R annexin A2 receptor 2.82824
NFE2 nuclear factor, erythroid 2 2.82824
TSSK1B testis-specific serine kinase 1B 2.82824
NRGN neurogranin (protein kinase C substrate, RC3) 2.82824
KIAA1755 KIAA1755 2.82824
NEUROD4 neuronal differentiation 4 2.82824
ASCL3 achaete-scute family bHLH transcription factor 3 2.82824
SDSL serine dehydratase-like 2.82824
CCDC83 coiled-coil domain containing 83 2.82824
FGF6 fibroblast growth factor 6 2.82824
CNOT6L CCR4-NOT transcription complex, subunit 6-like 2.82824
TMCO5A transmembrane and coiled-coil domains 5A 2.82824
TSHZ1 teashirt zinc finger homeobox 1 2.82824
CPLX3 complexin 3 2.82824
PRR22 proline rich 22 2.82824
UBASH3B ubiquitin associated and SH3 domain containing B 2.82824
FAM9B family with sequence similarity 9, member B 2.82824
DNAH2 dynein, axonemal, heavy chain 2 2.82824
LHB luteinizing hormone beta polypeptide 2.82824
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 2.82824
ACKR3 atypical chemokine receptor 3 2.82824
DMTN dematin actin binding protein 2.82824
TBC1D26 TBC1 domain family, member 26 2.82824
LGALS4 lectin, galactoside-binding, soluble, 4 2.82824
PSORS1C2 psoriasis susceptibility 1 candidate 2 2.82824
HHIPL2 HHIP-like 2 2.82824
GPBAR1 G protein-coupled bile acid receptor 1 2.82824
CD8A CD8a molecule 2.82824
MAGEA12 melanoma antigen family A12 2.82824
TSKS testis-specific serine kinase substrate 2.82824
MEX3B mex-3 RNA binding family member B 2.79384
JPH2 junctophilin 2 2.67966
HSPB8 heat shock 22kDa protein 8 2.67966
ACVR1B activin A receptor, type IB 2.62271
GNS glucosamine (N-acetyl)-6-sulfatase 2.56625
KIF3C kinesin family member 3C 2.48162
BAIAP3 BAI1-associated protein 3 2.44076
LRRD1 leucine-rich repeats and death domain containing 1 2.43741
KANK1 KN motif and ankyrin repeat domains 1 2.40325
BAG1 BCL2-associated athanogene 2.37637
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 2.36416
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 2.36416
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 2.36416
FMO4 flavin containing monooxygenase 4 2.35534
VN1R1 vomeronasal 1 receptor 1 2.34518
HAUS7 HAUS augmin-like complex, subunit 7 2.32559
FTH1 ferritin, heavy polypeptide 1 2.31622
C11ORF68 chromosome 11 open reading frame 68 2.29498
FAM78A family with sequence similarity 78, member A 2.28812
PHIP pleckstrin homology domain interacting protein 2.27923
TRAF3IP2 TRAF3 interacting protein 2 2.26838
DXO decapping exoribonuclease 2.23707
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 2.23707
SASH1 SAM and SH3 domain containing 1 2.2231
NES nestin 2.2231
VSNL1 visinin-like 1 2.20233
PNRC2 proline-rich nuclear receptor coactivator 2 2.16206
SV2B synaptic vesicle glycoprotein 2B 2.15489
CCR5AS CCR5 antisense RNA 2.14401
UBN1 ubinuclein 1 2.13827
POFUT1 protein O-fucosyltransferase 1 2.11028
LZTFL1 leucine zipper transcription factor-like 1 2.10596
HSBP1 heat shock factor binding protein 1 2.10576
BAIAP2L2 BAI1-associated protein 2-like 2 2.09582
CAMTA2 calmodulin binding transcription activator 2 2.074
PPIL4 peptidylprolyl isomerase (cyclophilin)-like 4 2.06373
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase 2.06373
ATN1 atrophin 1 2.04829
MRPS7 mitochondrial ribosomal protein S7 2.04699
SIRT5 sirtuin 5 2.03797
D2HGDH D-2-hydroxyglutarate dehydrogenase 2.03611
RBM41 RNA binding motif protein 41 2.02762
HP1BP3 heterochromatin protein 1, binding protein 3 2.01923
CEBPZOS CEBPZ opposite strand 2.00495

decreased expression

Symbol Name Standardized Value
SCN4B sodium channel, voltage gated, type IV beta subunit -2.87612
BMP2 bone morphogenetic protein 2 -2.82824
LINGO3 leucine rich repeat and Ig domain containing 3 -2.82824
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic -2.82824
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 -2.82824
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 -2.82824
TBX20 T-box 20 -2.82824
DRICH1 aspartate-rich 1 -2.82824
EDEM2 ER degradation enhancer, mannosidase alpha-like 2 -2.82824
PTGER3 prostaglandin E receptor 3 (subtype EP3) -2.82824
DKK2 dickkopf WNT signaling pathway inhibitor 2 -2.82824
CD68 CD68 molecule -2.82824
S100A2 S100 calcium binding protein A2 -2.82824
HIGD1C HIG1 hypoxia inducible domain family, member 1C -2.82824
HES7 hes family bHLH transcription factor 7 -2.82824
TLDC2 TBC/LysM-associated domain containing 2 -2.82824
PABPC1L2A poly(A) binding protein, cytoplasmic 1-like 2A -2.82824
GDF5 growth differentiation factor 5 -2.82824
KRT80 keratin 80, type II -2.82824
GOLGA8R golgin A8 family, member R -2.82824
ADRA2A adrenoceptor alpha 2A -2.82824
TM4SF19 transmembrane 4 L six family member 19 -2.82824
GNMT glycine N-methyltransferase -2.82824
TERB1 telomere repeat binding bouquet formation protein 1 -2.82824
GSDMA gasdermin A -2.82824
TPPP2 tubulin polymerization-promoting protein family member 2 -2.82824
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 -2.82824
LCN2 lipocalin 2 -2.82824
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 -2.82824
OTOF otoferlin -2.82824
SMIM24 small integral membrane protein 24 -2.82824
LGR6 leucine-rich repeat containing G protein-coupled receptor 6 -2.8104
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3 -2.8104
GOT1 glutamic-oxaloacetic transaminase 1, soluble -2.77804
TBL2 transducin (beta)-like 2 -2.77714
PPP4R3B protein phosphatase 4 regulatory subunit 3B -2.77139
CLPSL1 colipase-like 1 -2.72125
SEC24D SEC24 family member D -2.64598
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 -2.62724
STPG4 sperm-tail PG-rich repeat containing 4 -2.58727
CNOT6 CCR4-NOT transcription complex, subunit 6 -2.58077
SDF2 stromal cell-derived factor 2 -2.57463
PHOSPHO2 phosphatase, orphan 2 -2.56318
MICU2 mitochondrial calcium uptake 2 -2.55325
CENPU centromere protein U -2.53655
SLFN12 schlafen family member 12 -2.52376
MTERF1 mitochondrial transcription termination factor 1 -2.47714
UBR1 ubiquitin protein ligase E3 component n-recognin 1 -2.4555
PRSS53 protease, serine, 53 -2.4535
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 -2.45228
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 -2.41772
FAM222B family with sequence similarity 222, member B -2.39123
SMIM13 small integral membrane protein 13 -2.35582
SLIT1 slit homolog 1 (Drosophila) -2.34252
GAGE10 G antigen 10 -2.28581
EFCAB6 EF-hand calcium binding domain 6 -2.28581
TP53TG5 TP53 target 5 -2.28581
TMC7 transmembrane channel-like 7 -2.28581
CDC25A cell division cycle 25A -2.26291
UFL1 UFM1-specific ligase 1 -2.25036
BAG5 BCL2-associated athanogene 5 -2.22387
FARSB phenylalanyl-tRNA synthetase, beta subunit -2.21404
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase -2.20598
SNX12 sorting nexin 12 -2.20598
OXR1 oxidation resistance 1 -2.20598
CLDN20 claudin 20 -2.20212
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) -2.19994
SOX10 SRY (sex determining region Y)-box 10 -2.16334
GIP gastric inhibitory polypeptide -2.16206
CCDC39 coiled-coil domain containing 39 -2.16206
PLD3 phospholipase D family, member 3 -2.14401
MPZ myelin protein zero -2.11838
TMEM170A transmembrane protein 170A -2.11838
FAF1 Fas (TNFRSF6) associated factor 1 -2.10576
WASHC3 WASH complex subunit 3 -2.10576
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 -2.09467
PRMT6 protein arginine methyltransferase 6 -2.09467
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit -2.09158
CAPN12 calpain 12 -2.09139
CMC1 C-x(9)-C motif containing 1 -2.074
ZNF124 zinc finger protein 124 -2.06546
SPMIP2 sperm microtubule inner protein 2 -2.06196
SEC16A SEC16 homolog A (S. cerevisiae) -2.05513
RPSA2 ribosomal protein SA 2 -2.05024
NICOL1 NELL2 interacting cell ontogeny regulator 1 -2.04829
CHODL chondrolectin -2.04571
MICALL2 MICAL-like 2 -2.02577
LAMA4 laminin, alpha 4 -2.02577
CDNF cerebral dopamine neurotrophic factor -2.02577
CATSPERQ catsper channel auxiliary subunit theta -2.02577
TCAF1 TRPM8 channel-associated factor 1 -2.0174
CRIPTO3 cripto, EGF-CFC family member 3 -2.00575
SPSB2 splA/ryanodine receptor domain and SOCS box containing 2 -2.00495
BOLA2B bolA family member 2B -2.00107