PGAP1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description post-GPI attachment to proteins 1|PGAP1 catalyzes the inositol deacylation of glycosylphosphatidylinositol (GPI) at an early step in GPI biosynthesis. Inositol deacylation is essential for the generation of mature GPI capable of attachment to proteins (Tanaka et al., 2004 [PubMed 14734546]).[supplied by OMIM, Mar 2008] (NCBI Entrez Gene Database, 80055)
External Link https://ncbi.nlm.nih.gov/gene/80055
Similar Terms
Downloads & Tools

Genes

500 genes differentially expressed following the PGAP1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
BIRC3 baculoviral IAP repeat containing 3 0.013077
HOXB7 homeobox B7 0.0125578
SELL selectin L 0.0121024
HIST1H2AC histone cluster 1, H2ac 0.0120766
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.0117007
CXCL8 chemokine (C-X-C motif) ligand 8 0.0115692
CSTA cystatin A (stefin A) 0.0114991
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 0.0111255
ZNF589 zinc finger protein 589 0.0110598
CD69 CD69 molecule 0.0108466
SORD sorbitol dehydrogenase 0.0107151
H1-2 H1.2 linker histone, cluster member 0.0102268
CCL20 chemokine (C-C motif) ligand 20 0.0101399
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.0100293
LY75 lymphocyte antigen 75 0.00998911
PRAME preferentially expressed antigen in melanoma 0.00996146
ADD3 adducin 3 (gamma) 0.00993329
CXCL3 chemokine (C-X-C motif) ligand 3 0.00992966
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00980582
PITX3 paired-like homeodomain 3 0.00974013
GJA1 gap junction protein, alpha 1, 43kDa 0.00973054
MAL mal, T-cell differentiation protein 0.00968647
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.00954239
C6ORF48 chromosome 6 open reading frame 48 0.00950474
S100A7 S100 calcium binding protein A7 0.00931124
WFDC1 WAP four-disulfide core domain 1 0.00913109
P3H2 prolyl 3-hydroxylase 2 0.00912232
PRSS21 protease, serine, 21 (testisin) 0.00906368
CHKB choline kinase beta 0.00902705
AOC1 amine oxidase, copper containing 1 0.00899575
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.00894127
RGS10 regulator of G-protein signaling 10 0.00893438
CCR7 chemokine (C-C motif) receptor 7 0.00891702
KYNU kynureninase 0.00891176
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 0.00887594
GALC galactosylceramidase 0.00885111
TBC1D31 TBC1 domain family, member 31 0.00882274
AQP3 aquaporin 3 (Gill blood group) 0.00879903
ZNF185 zinc finger protein 185 (LIM domain) 0.00873875
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.00869786
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.00869087
KLF10 Kruppel-like factor 10 0.00864692
KRT5 keratin 5, type II 0.0085703
ACP3 acid phosphatase 3 0.00854697
HOXB6 homeobox B6 0.00845181
SRGN serglycin 0.00844205
SLC25A46 solute carrier family 25, member 46 0.00843202
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00827269
MAT2B methionine adenosyltransferase II, beta 0.00824524
TUBB2A tubulin, beta 2A class IIa 0.00824414
LGALS13 lectin, galactoside-binding, soluble, 13 0.00807205
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 0.00805656
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.00805292
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.007978
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.00789251
SVIL supervillin 0.00783362
CXCL2 chemokine (C-X-C motif) ligand 2 0.00774292
COL4A5 collagen, type IV, alpha 5 0.00771733
LCN2 lipocalin 2 0.0076661
IL2RG interleukin 2 receptor, gamma 0.00766516
BTG3 BTG family, member 3 0.00760814
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 0.0075811
BCL2A1 BCL2-related protein A1 0.00756232
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.00754751
AKR1C3 aldo-keto reductase family 1, member C3 0.00752058
MMP1 matrix metallopeptidase 1 0.00750889
HIST1H2BK histone cluster 1, H2bk 0.0074874
VNN1 vanin 1 0.00745744
NFIL3 nuclear factor, interleukin 3 regulated 0.0074389
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 0.00742251
TSC22D3 TSC22 domain family, member 3 0.00731673
KIAA0226L KIAA0226-like 0.00729408
NELL2 NEL-like 2 (chicken) 0.00728496
ANXA3 annexin A3 0.00726622
DDIT3 DNA-damage-inducible transcript 3 0.00725052
ZEB1 zinc finger E-box binding homeobox 1 0.00723494
LRRN3 leucine rich repeat neuronal 3 0.00722973
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 0.00721881
CETN2 centrin, EF-hand protein, 2 0.00714688
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.00714525
GYPC glycophorin C (Gerbich blood group) 0.00713211
YPEL5 yippee-like 5 (Drosophila) 0.00712419
TLK1 tousled-like kinase 1 0.00711459
WNT5A wingless-type MMTV integration site family, member 5A 0.00710214
CRISP3 cysteine-rich secretory protein 3 0.00708312
GSTM3 glutathione S-transferase mu 3 (brain) 0.00707688
MLF1 myeloid leukemia factor 1 0.00707035
TRH thyrotropin-releasing hormone 0.00703362
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.00702729
SELE selectin E 0.00697984
MEIS1 Meis homeobox 1 0.00697306
ATXN1 ataxin 1 0.00696367
STOM stomatin 0.00694308
LPAR6 lysophosphatidic acid receptor 6 0.00693222
ATF3 activating transcription factor 3 0.00692463
PCYOX1L prenylcysteine oxidase 1 like 0.00690611
CCNI cyclin I 0.00687989
LYRM1 LYR motif containing 1 0.00687683
DNASE1L3 deoxyribonuclease I-like 3 0.00685105
IFT52 intraflagellar transport 52 0.00683862
RGS2 regulator of G-protein signaling 2 0.00683177
CAV2 caveolin 2 0.00681789
ARHGAP15 Rho GTPase activating protein 15 0.00679999
BPI bactericidal/permeability-increasing protein 0.0067807
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.00676506
SIDT1 SID1 transmembrane family, member 1 0.00675662
DCK deoxycytidine kinase 0.00673717
IQCG IQ motif containing G 0.00672967
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.00671106
CD2AP CD2-associated protein 0.00671041
CD83 CD83 molecule 0.00670964
SRP72 signal recognition particle 72kDa 0.00667883
CSRP2 cysteine and glycine-rich protein 2 0.00660155
XK X-linked Kx blood group 0.00658876
BAMBI BMP and activin membrane-bound inhibitor 0.006583
ZNF184 zinc finger protein 184 0.00657628
FOSL2 FOS-like antigen 2 0.00657189
MAP2K6 mitogen-activated protein kinase kinase 6 0.00654393
LTBP1 latent transforming growth factor beta binding protein 1 0.00650511
JUNB jun B proto-oncogene 0.00650042
HIST1H2BD histone cluster 1, H2bd 0.0064946
DUSP2 dual specificity phosphatase 2 0.00647771
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.00646972
ITK IL2-inducible T-cell kinase 0.00645745
IFI44 interferon-induced protein 44 0.00645454
MMP12 matrix metallopeptidase 12 0.00645079
TCF21 transcription factor 21 0.00642685
IL6ST interleukin 6 signal transducer 0.00640304
ODC1 ornithine decarboxylase 1 0.00639356
USP46 ubiquitin specific peptidase 46 0.00637913
ICOS inducible T-cell co-stimulator 0.00635897
PLK1 polo-like kinase 1 0.00635642
NIBAN1 niban apoptosis regulator 1 0.0063552
PDE4D phosphodiesterase 4D, cAMP-specific 0.00635367
CCL15 chemokine (C-C motif) ligand 15 0.00635215
GPR171 G protein-coupled receptor 171 0.00634397
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 0.00634117
CDC42 cell division cycle 42 0.0063096
DNMBP dynamin binding protein 0.00629806
SET SET nuclear proto-oncogene 0.00627965
COPS4 COP9 signalosome subunit 4 0.00625726
CAB39 calcium binding protein 39 0.0062532
WLS wntless Wnt ligand secretion mediator 0.00624527
LAMC2 laminin, gamma 2 0.00623837
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.00623324
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 0.00621471
OARD1 O-acyl-ADP-ribose deacylase 1 0.00620372
ZNF267 zinc finger protein 267 0.00619729
GCH1 GTP cyclohydrolase 1 0.00619149
ISG20 interferon stimulated exonuclease gene 20kDa 0.00618861
SLC16A4 solute carrier family 16, member 4 0.00618778
CRIPT cysteine-rich PDZ-binding protein 0.00618573
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.00617959
EAPP E2F-associated phosphoprotein 0.00616844
TFRC transferrin receptor 0.00615815
MRPS10 mitochondrial ribosomal protein S10 0.00615567
C12ORF29 chromosome 12 open reading frame 29 0.00615229
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.00613212
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.00612178
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00611387
MXI1 MAX interactor 1, dimerization protein 0.00608398
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 0.00606592
AKAP11 A kinase (PRKA) anchor protein 11 0.00606249
IL15 interleukin 15 0.00605281
GPA33 glycoprotein A33 (transmembrane) 0.00604909
IVNS1ABP influenza virus NS1A binding protein 0.00604426
CLMN calmin (calponin-like, transmembrane) 0.00604213
KAT2B K(lysine) acetyltransferase 2B 0.0060383
FAM46C family with sequence similarity 46, member C 0.00602572
KDM5B lysine (K)-specific demethylase 5B 0.00601906
ARL4A ADP-ribosylation factor-like 4A 0.00600475
JAM2 junctional adhesion molecule 2 0.00600219
ERAP2 endoplasmic reticulum aminopeptidase 2 0.00598895
ECI2 enoyl-CoA delta isomerase 2 0.0059731
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 0.00595885
NME7 NME/NM23 family member 7 0.00595852
CCDC176 coiled-coil domain containing 176 0.00594782
CAMP cathelicidin antimicrobial peptide 0.00594717
HDAC9 histone deacetylase 9 0.0059441
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0059371
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.00592264
CD27 CD27 molecule 0.0059217
ZDHHC14 zinc finger, DHHC-type containing 14 0.00591786
GNG12 guanine nucleotide binding protein (G protein), gamma 12 0.00589362
VCPKMT valosin containing protein lysine (K) methyltransferase 0.00588339
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.00587967
RHCG Rh family, C glycoprotein 0.00587762
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 0.00585863
H1-10 H1.10 linker histone 0.00585508
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) 0.00585156
SNRK SNF related kinase 0.00584971
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 0.00584472
TMEM168 transmembrane protein 168 0.00584411
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase 0.00584037
MARCKS myristoylated alanine-rich protein kinase C substrate 0.00583811
MICA MHC class I polypeptide-related sequence A 0.00583519
ACSM3 acyl-CoA synthetase medium-chain family member 3 0.00583313
IL18RAP interleukin 18 receptor accessory protein 0.00582723
CHPT1 choline phosphotransferase 1 0.00582656
TXNIP thioredoxin interacting protein 0.00581359
PLCL2 phospholipase C-like 2 0.00579959
H2AFV H2A histone family, member V 0.00579351
TMEM242 transmembrane protein 242 0.00578008
ALAS2 5'-aminolevulinate synthase 2 0.0057783
BPGM 2,3-bisphosphoglycerate mutase 0.0057632
PAQR3 progestin and adipoQ receptor family member III 0.00575592
EGLN3 egl-9 family hypoxia-inducible factor 3 0.00575194
LOC730101 uncharacterized LOC730101 0.00574576
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 0.00574494
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 0.00574049
HBZ hemoglobin, zeta 0.00573425
SLC44A4 solute carrier family 44, member 4 0.00567886
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00565854
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.00565567
DEFA4 defensin, alpha 4, corticostatin 0.00565407
RPA2 replication protein A2, 32kDa 0.00565261
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 0.00564542
MYNN myoneurin 0.00563115
JAG1 jagged 1 0.0056263
CFLAR CASP8 and FADD-like apoptosis regulator 0.00561614
CD44 CD44 molecule (Indian blood group) 0.00561045
TJP2 tight junction protein 2 0.00560541
ZCCHC10 zinc finger, CCHC domain containing 10 0.00560054
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 0.00557701
ZBTB18 zinc finger and BTB domain containing 18 0.00556473
MAGEA3 melanoma antigen family A3 0.00556077
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) 0.00555814
MGAM maltase-glucoamylase 0.00553877
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 0.00553215
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00553044
RAB4A RAB4A, member RAS oncogene family 0.00552291
BABAM2 BRISC and BRCA1 A complex member 2 0.0055039
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 0.00550287
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 0.00547286
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent 0.00546974
MPO myeloperoxidase 0.0054674
TMPRSS2 transmembrane protease, serine 2 0.00546642
RPP40 ribonuclease P/MRP 40kDa subunit 0.00545561
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.00544842
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 0.00544532
ANKRD28 ankyrin repeat domain 28 0.00544451
PRKD1 protein kinase D1 0.00544184
CEP68 centrosomal protein 68kDa 0.00543907
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 0.00542115
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00542009
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.00541017
CAV1 caveolin 1, caveolae protein, 22kDa 0.00540799
ADM adrenomedullin 0.00540666
IER2 immediate early response 2 0.00540211
BLNK B-cell linker 0.00540095

decreased expression

Symbol Name Standardized Value
CADM1 cell adhesion molecule 1 -0.0162287
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.0138989
KRT23 keratin 23, type I -0.0138034
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.0130907
PXDN peroxidasin -0.0123664
TCTA T-cell leukemia translocation altered -0.0122832
C3 complement component 3 -0.0120106
MMP2 matrix metallopeptidase 2 -0.0115087
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -0.0109278
ASPN asporin -0.0108794
PCNA proliferating cell nuclear antigen -0.0107693
SFTPB surfactant protein B -0.0105703
TAGLN transgelin -0.010416
PDGFRL platelet-derived growth factor receptor-like -0.0103918
MFAP5 microfibrillar associated protein 5 -0.0103314
PLXND1 plexin D1 -0.0103007
KRT7 keratin 7, type II -0.0102819
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -0.0101717
HYOU1 hypoxia up-regulated 1 -0.0100288
MBL2 mannose-binding lectin (protein C) 2, soluble -0.00989505
PLAAT3 phospholipase A and acyltransferase 3 -0.00960503
TFF3 trefoil factor 3 (intestinal) -0.00951822
ADCY9 adenylate cyclase 9 -0.00949251
H2AX H2A.X variant histone -0.00941845
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.00930583
MEF2C myocyte enhancer factor 2C -0.00928279
SPON2 spondin 2, extracellular matrix protein -0.0092755
ANKRD11 ankyrin repeat domain 11 -0.00918375
MTUS1 microtubule associated tumor suppressor 1 -0.00914759
PPIB peptidylprolyl isomerase B (cyclophilin B) -0.00912089
FABP4 fatty acid binding protein 4, adipocyte -0.0091031
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.00908036
LMO2 LIM domain only 2 (rhombotin-like 1) -0.00905162
CD9 CD9 molecule -0.00903217
HSPA1A heat shock 70kDa protein 1A -0.00900706
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 -0.0090046
KIAA0930 KIAA0930 -0.00900061
ANPEP alanyl (membrane) aminopeptidase -0.00894671
RAP2A RAP2A, member of RAS oncogene family -0.00888303
MYBPC1 myosin binding protein C, slow type -0.00881948
A2M alpha-2-macroglobulin -0.00868282
PTGIS prostaglandin I2 (prostacyclin) synthase -0.00864652
DYNLL1 dynein, light chain, LC8-type 1 -0.0086464
ACADVL acyl-CoA dehydrogenase, very long chain -0.00862919
LY6E lymphocyte antigen 6 complex, locus E -0.00857527
KRAS Kirsten rat sarcoma viral oncogene homolog -0.00856114
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00852851
THBS2 thrombospondin 2 -0.0085086
GLUL glutamate-ammonia ligase -0.00848453
KANK1 KN motif and ankyrin repeat domains 1 -0.00839764
SFRP4 secreted frizzled-related protein 4 -0.00837165
RNPS1 RNA binding protein S1, serine-rich domain -0.00824995
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00824049
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00819613
ADI1 acireductone dioxygenase 1 -0.00819352
LAT2 linker for activation of T cells family, member 2 -0.00813619
NKX2-1 NK2 homeobox 1 -0.00813094
CXCR4 chemokine (C-X-C motif) receptor 4 -0.00811374
COMP cartilage oligomeric matrix protein -0.00805188
C1S complement component 1, s subcomponent -0.00805086
MEG3 maternally expressed 3 (non-protein coding) -0.00803923
ASS1 argininosuccinate synthase 1 -0.00793989
ASCL1 achaete-scute family bHLH transcription factor 1 -0.007938
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -0.00788047
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00784714
PLXNC1 plexin C1 -0.00780217
MTF2 metal response element binding transcription factor 2 -0.00778683
SPIN1 spindlin 1 -0.00777234
INSM1 insulinoma-associated 1 -0.00774691
MPRIP myosin phosphatase Rho interacting protein -0.00774021
DUSP4 dual specificity phosphatase 4 -0.00773175
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00772687
CALCA calcitonin-related polypeptide alpha -0.00771277
SRSF1 serine/arginine-rich splicing factor 1 -0.0076809
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.00764517
SRPRA SRP receptor subunit alpha -0.00764252
TIMP1 TIMP metallopeptidase inhibitor 1 -0.00760976
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 -0.00760343
TNNI2 troponin I type 2 (skeletal, fast) -0.00759233
RAPSN receptor-associated protein of the synapse -0.00758058
PLK2 polo-like kinase 2 -0.00753872
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -0.0075267
STIP1 stress-induced phosphoprotein 1 -0.00749264
EML3 echinoderm microtubule associated protein like 3 -0.00745857
DCLK1 doublecortin-like kinase 1 -0.0074496
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 -0.00742397
FAM3C family with sequence similarity 3, member C -0.00739601
PUM1 pumilio RNA-binding family member 1 -0.0073899
ACTB actin, beta -0.00738412
CTBP2 C-terminal binding protein 2 -0.00737467
RUFY3 RUN and FYVE domain containing 3 -0.00732383
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 -0.00732239
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) -0.00729537
ICMT isoprenylcysteine carboxyl methyltransferase -0.00727224
CP ceruloplasmin (ferroxidase) -0.00727078
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 -0.00725894
MFSD10 major facilitator superfamily domain containing 10 -0.00722797
TIMP3 TIMP metallopeptidase inhibitor 3 -0.0072042
SFTPA2 surfactant protein A2 -0.00717564
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 -0.00717334
RAP1GAP RAP1 GTPase activating protein -0.0071698
ABHD2 abhydrolase domain containing 2 -0.00716086
CEL carboxyl ester lipase -0.00707581
CFH complement factor H -0.00702856
CSNK1E casein kinase 1, epsilon -0.00700269
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase -0.00697557
HMGB1 high mobility group box 1 -0.00696783
THBS4 thrombospondin 4 -0.0069628
CD163 CD163 molecule -0.00694525
BCAP31 B-cell receptor-associated protein 31 -0.00692994
FBXO2 F-box protein 2 -0.00690101
FGL1 fibrinogen-like 1 -0.00688838
C1R complement component 1, r subcomponent -0.00688813
DTX4 deltex 4, E3 ubiquitin ligase -0.00685034
MAN2A1 mannosidase, alpha, class 2A, member 1 -0.00682426
C4BPA complement component 4 binding protein, alpha -0.00682373
FN1 fibronectin 1 -0.00681234
MAEA macrophage erythroblast attacher -0.0067941
CHD4 chromodomain helicase DNA binding protein 4 -0.00678039
SC5D sterol-C5-desaturase -0.00676485
CCDC92 coiled-coil domain containing 92 -0.00676252
ACAD8 acyl-CoA dehydrogenase family, member 8 -0.00674859
BEX1 brain expressed, X-linked 1 -0.00673997
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.00673577
IRAK1 interleukin-1 receptor-associated kinase 1 -0.00669844
FGL2 fibrinogen-like 2 -0.00667434
MCM5 minichromosome maintenance complex component 5 -0.00665643
FBXW12 F-box and WD repeat domain containing 12 -0.00665268
PPARG peroxisome proliferator-activated receptor gamma -0.00664153
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -0.00663011
TUBB4B tubulin, beta 4B class IVb -0.00662967
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -0.006599
PTPRE protein tyrosine phosphatase, receptor type, E -0.00658158
SETBP1 SET binding protein 1 -0.00658084
APLP2 amyloid beta (A4) precursor-like protein 2 -0.0065298
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 -0.00652933
LRRC15 leucine rich repeat containing 15 -0.00651827
STK25 serine/threonine kinase 25 -0.0065046
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.0065017
ACTA1 actin, alpha 1, skeletal muscle -0.00649377
CLDN3 claudin 3 -0.00648958
PDIA4 protein disulfide isomerase family A, member 4 -0.00648591
SNX7 sorting nexin 7 -0.00647891
KLHL41 kelch-like family member 41 -0.00647783
GRAMD4 GRAM domain containing 4 -0.00646629
NFIB nuclear factor I/B -0.00646444
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 -0.0064644
CNN3 calponin 3, acidic -0.00643368
CRLF1 cytokine receptor-like factor 1 -0.00640824
IFI30 interferon, gamma-inducible protein 30 -0.00640392
ETV5 ets variant 5 -0.00640091
TOX3 TOX high mobility group box family member 3 -0.00639765
PIGG phosphatidylinositol glycan anchor biosynthesis, class G -0.00639026
PTPRD protein tyrosine phosphatase, receptor type, D -0.00636542
LIMCH1 LIM and calponin homology domains 1 -0.00634915
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -0.00634903
ALB albumin -0.00633651
GAS6 growth arrest-specific 6 -0.00626977
FNDC3B fibronectin type III domain containing 3B -0.00626859
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) -0.00626105
ELF5 E74-like factor 5 (ets domain transcription factor) -0.00624258
CD320 CD320 molecule -0.00623654
ZNF91 zinc finger protein 91 -0.00622631
KRT19 keratin 19, type I -0.00621124
KIF1A kinesin family member 1A -0.00620103
RALGDS ral guanine nucleotide dissociation stimulator -0.00618126
SST somatostatin -0.00617724
S100A4 S100 calcium binding protein A4 -0.00617654
SPRY2 sprouty homolog 2 (Drosophila) -0.00617111
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00616462
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A -0.00615267
CYRIA CYFIP related Rac1 interactor A -0.0061192
LDOC1 leucine zipper, down-regulated in cancer 1 -0.00610796
ATP5ME ATP synthase membrane subunit e -0.00610658
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) -0.00609619
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -0.00609571
SMC1A structural maintenance of chromosomes 1A -0.00609426
KLF6 Kruppel-like factor 6 -0.00608505
MED13 mediator complex subunit 13 -0.00607649
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.00607456
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.00607002
ENAH enabled homolog (Drosophila) -0.00606559
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -0.00605056
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -0.00605037
OXTR oxytocin receptor -0.00604872
MELK maternal embryonic leucine zipper kinase -0.00604424
CANT1 calcium activated nucleotidase 1 -0.00602057
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.00602015
UBE4A ubiquitination factor E4A -0.00599824
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) -0.0059771
IVD isovaleryl-CoA dehydrogenase -0.0059732
PPL periplakin -0.00595837
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) -0.00594618
MCUB mitochondrial calcium uniporter dominant negative subunit beta -0.00594093
SDC2 syndecan 2 -0.00594056
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) -0.00593429
AKAP1 A kinase (PRKA) anchor protein 1 -0.0059332
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.00592213
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00591935
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00591554
DVL1 dishevelled segment polarity protein 1 -0.00590756
SOX11 SRY (sex determining region Y)-box 11 -0.00589629
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -0.00588715
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -0.0058767
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.00587408
TLCD3A TLC domain containing 3A -0.00586533
FKBP2 FK506 binding protein 2, 13kDa -0.00586451
ZNF160 zinc finger protein 160 -0.00586082
WSB1 WD repeat and SOCS box containing 1 -0.00585484
FADS1 fatty acid desaturase 1 -0.00585393
GLA galactosidase, alpha -0.0058393
KLF2 Kruppel-like factor 2 -0.00583531
PHC2 polyhomeotic homolog 2 (Drosophila) -0.00582945
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 -0.00582788
LEPROT leptin receptor overlapping transcript -0.00580405
CCR1 chemokine (C-C motif) receptor 1 -0.00579554
SLIT2 slit homolog 2 (Drosophila) -0.00578563
RBPMS RNA binding protein with multiple splicing -0.00578458
RAB14 RAB14, member RAS oncogene family -0.0057785
GAS7 growth arrest-specific 7 -0.00577785
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta -0.00577726
CHGB chromogranin B -0.00577641
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -0.00577608
CD63 CD63 molecule -0.00576918
STEAP3 STEAP family member 3, metalloreductase -0.00576088
CELF2 CUGBP, Elav-like family member 2 -0.00574477
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -0.00572838
FOXO3 forkhead box O3 -0.00572734
PDGFD platelet derived growth factor D -0.0057266
IGFBP6 insulin-like growth factor binding protein 6 -0.00572284
ARL5A ADP-ribosylation factor-like 5A -0.00571945
ELAC2 elaC ribonuclease Z 2 -0.00571678
CLU clusterin -0.0057001
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 -0.00569151
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.00568507
FLII flightless I homolog (Drosophila) -0.00568439
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00567301
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.0056638
HMGB3 high mobility group box 3 -0.0056434
TMEM176B transmembrane protein 176B -0.00562001
TSPYL5 TSPY-like 5 -0.00560553
PRDX1 peroxiredoxin 1 -0.00559829
TYROBP TYRO protein tyrosine kinase binding protein -0.00559244
MYH11 myosin, heavy chain 11, smooth muscle -0.00558049
CALHM2 calcium homeostasis modulator 2 -0.00556514
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -0.00555812
FEN1 flap structure-specific endonuclease 1 -0.00554936
ELOVL1 ELOVL fatty acid elongase 1 -0.00554794
KIF5B kinesin family member 5B -0.00554076
RRBP1 ribosome binding protein 1 -0.00553454