PGAP2 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description post-GPI attachment to proteins 2 (NCBI Entrez Gene Database, 27315)
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Genes

319 genes differentially expressed following the PGAP2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
CCDC152 coiled-coil domain containing 152 2.29935
PAX6 paired box 6 2.29935
ZNF471 zinc finger protein 471 2.29935
PEAR1 platelet endothelial aggregation receptor 1 2.29935
LAMA4 laminin, alpha 4 2.29935
PSKH2 protein serine kinase H2 2.29935
ZFP57 ZFP57 zinc finger protein 2.29935
PRELP proline/arginine-rich end leucine-rich repeat protein 2.29935
JSRP1 junctional sarcoplasmic reticulum protein 1 2.29935
OPLAH 5-oxoprolinase (ATP-hydrolysing) 2.29935
DGCR6 DiGeorge syndrome critical region gene 6 2.29935
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 2.29935
OVOL3 ovo-like zinc finger 3 2.29935
INHBE inhibin, beta E 2.29935
SCARA5 scavenger receptor class A, member 5 2.29935
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 2.29935
PRPH2 peripherin 2 (retinal degeneration, slow) 2.29935
ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2 2.29935
C1ORF232 chromosome 1 open reading frame 230 2.29935
PITX3 paired-like homeodomain 3 2.29935
RHOJ ras homolog family member J 2.29935
NTN5 netrin 5 2.29935
TSPAN14 tetraspanin 14 2.29935
SMIM41 small integral membrane protein 41 2.29935
ZNF875 zinc finger protein 875 2.28491
FAM216B family with sequence similarity 216, member B 2.25147
IL2RA interleukin 2 receptor, alpha 2.25147
TCP11 t-complex 11, testis-specific 2.25147
DNASE1L2 deoxyribonuclease I-like 2 2.25147
CD209 CD209 molecule 2.25147
CCNJL cyclin J-like 2.25147
CORO6 coronin 6 2.25147
ACR acrosin 2.25147
TMEM144 transmembrane protein 144 2.25147
SIX3 SIX homeobox 3 2.25147
CST11 cystatin 11 2.25147
SLC25A47 solute carrier family 25, member 47 2.25147
IL4I1 interleukin 4 induced 1 2.25147
DIO3 deiodinase, iodothyronine, type III 2.25147
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 2.25147
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 2.25147
CX3CR1 chemokine (C-X3-C motif) receptor 1 2.25147
GLUD2 glutamate dehydrogenase 2 2.25147
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 2.25147
UNC45B unc-45 homolog B (C. elegans) 2.25147
RFPL3 ret finger protein-like 3 2.25147
C11ORF87 chromosome 11 open reading frame 87 2.25147
NRROS negative regulator of reactive oxygen species 2.25147
ATF7 activating transcription factor 7 2.25147
ZNF615 zinc finger protein 615 2.25147
ARPP21 cAMP-regulated phosphoprotein, 21kDa 2.25147
HCRTR2 hypocretin (orexin) receptor 2 2.25147
SLC30A2 solute carrier family 30 (zinc transporter), member 2 2.25147
TUBB1 tubulin, beta 1 class VI 2.25147
PCDHB7 protocadherin beta 7 2.25147
SLC35G5 solute carrier family 35, member G5 2.25147
ZNF467 zinc finger protein 467 2.25147
SOX14 SRY (sex determining region Y)-box 14 2.25147
NCF2 neutrophil cytosolic factor 2 2.25147
RLN3 relaxin 3 2.25147
LASP1 LIM and SH3 protein 1 2.25147
NFAM1 NFAT activating protein with ITAM motif 1 2.25147
MOGAT3 monoacylglycerol O-acyltransferase 3 2.25147
CATSPERH catsper channel auxiliary subunit eta 2.25147
ALDOB aldolase B, fructose-bisphosphate 2.25147
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 2.25147
EIF4H eukaryotic translation initiation factor 4H 2.25147
MCHR2 melanin-concentrating hormone receptor 2 2.25147
AVPR1A arginine vasopressin receptor 1A 2.25147
CAPN9 calpain 9 2.25147
DUSP8 dual specificity phosphatase 8 2.25147
RD3 retinal degeneration 3 2.25147
FMO1 flavin containing monooxygenase 1 2.25147
TOGARAM1 TOG array regulator of axonemal microtubules 1 2.25147
SQOR sulfide quinone oxidoreductase 2.25147
DERPC DERPC proline and glycine rich nuclear protein 2.25147
ACKR5 atypical chemokine receptor 5 2.25147
NICOL1 NELL2 interacting cell ontogeny regulator 1 2.25147
LOC124906010 uncharacterized LOC124906010 2.25147
OR52P1 olfactory receptor family 52 subfamily P member 1 (gene/pseudogene) 2.25147
KASH5 KASH domain containing 5 2.25147
CBLIF cobalamin binding intrinsic factor 2.25147
GK3 glycerol kinase 3 2.25147
SLURP2 secreted LY6/PLAUR domain containing 2 2.25147
LOC124906892 uncharacterized LOC124906892 2.25147
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 2.25147
IQCF1 IQ motif containing F1 2.25147
PROZ protein Z, vitamin K-dependent plasma glycoprotein 2.25147
SCRT2 scratch family zinc finger 2 2.25147
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.25147
FAM78A family with sequence similarity 78, member A 2.25147
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 2.25147
TUBA3D tubulin, alpha 3d 2.25147
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 2.25147
ARL5C ADP-ribosylation factor-like 5C 2.25147
PRB4 proline-rich protein BstNI subfamily 4 2.25147
RAB44 RAB44, member RAS oncogene family 2.25147
TLR2 toll-like receptor 2 2.25147
NR0B1 nuclear receptor subfamily 0, group B, member 1 2.25147
PGA3 pepsinogen 3, group I (pepsinogen A) 2.25147
ASB5 ankyrin repeat and SOCS box containing 5 2.25147
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 2.25147
GATA3 GATA binding protein 3 2.25147
KL klotho 2.25147
CNTN4 contactin 4 2.25147
CNTN6 contactin 6 2.25147
HNF1A HNF1 homeobox A 2.25147
GPR84 G protein-coupled receptor 84 2.25147
PLEK2 pleckstrin 2 2.25147
FAM3D family with sequence similarity 3, member D 2.25147
AKNAD1 AKNA domain containing 1 2.25147
SPO11 SPO11 meiotic protein covalently bound to DSB 2.25147
OAZ3 ornithine decarboxylase antizyme 3 2.25147
CPA2 carboxypeptidase A2 (pancreatic) 2.25147
CBX8 chromobox homolog 8 2.25147
NREP neuronal regeneration related protein 2.25147
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 2.25147
PCDHGA2 protocadherin gamma subfamily A, 2 2.25147
COL17A1 collagen, type XVII, alpha 1 2.25147
CAMK2B calcium/calmodulin-dependent protein kinase II beta 2.25147
CST5 cystatin D 2.25147
LRTM2 leucine-rich repeats and transmembrane domains 2 2.25147
ZMYND10 zinc finger, MYND-type containing 10 2.25147
PKLR pyruvate kinase, liver and RBC 2.25147
SMIM22 small integral membrane protein 22 2.25147
GAL3ST2 galactose-3-O-sulfotransferase 2 2.25147
TMEM132E transmembrane protein 132E 2.25147
ZNF132 zinc finger protein 132 2.25147
EDN3 endothelin 3 2.25147
DYDC1 DPY30 domain containing 1 2.25147
ZCCHC12 zinc finger, CCHC domain containing 12 2.25147
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 2.25147
FBXO40 F-box protein 40 2.25147
CLEC1A C-type lectin domain family 1, member A 2.25147
MOBP myelin-associated oligodendrocyte basic protein 2.25147
NMBR neuromedin B receptor 2.25147
POU4F1 POU class 4 homeobox 1 2.25147
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 2.25147
ESPNL espin-like 2.25147
ADAM18 ADAM metallopeptidase domain 18 2.25147
GOLGA8M golgin A8 family, member M 2.25147
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 2.25147
IP6K3 inositol hexakisphosphate kinase 3 2.25147
ARL13A ADP-ribosylation factor-like 13A 2.25147
EGR2 early growth response 2 2.25147
SST somatostatin 2.25147
CFAP47 cilia and flagella associated protein 47 2.25147
LENEP lens epithelial protein 2.25147
SLCO2B1 solute carrier organic anion transporter family, member 2B1 2.25147
TAAR1 trace amine associated receptor 1 2.25147
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 2.25147
RIPPLY2 ripply transcriptional repressor 2 2.25147
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 2.25147
ASCL2 achaete-scute family bHLH transcription factor 2 2.25147
PARP15 poly (ADP-ribose) polymerase family, member 15 2.25147
ACADL acyl-CoA dehydrogenase, long chain 2.25147
APOL4 apolipoprotein L, 4 2.25147
ANGPTL3 angiopoietin-like 3 2.25147
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 2.25147
CLCNKB chloride channel, voltage-sensitive Kb 2.25147
ACAN aggrecan 2.25147
TEX38 testis expressed 38 2.25147
ICAM2 intercellular adhesion molecule 2 2.25147
XCR1 chemokine (C motif) receptor 1 2.25147
ASCL5 achaete-scute family bHLH transcription factor 5 2.25147
RCC1 regulator of chromosome condensation 1 2.25147
PADI1 peptidyl arginine deiminase, type I 2.25147
PPP1R3A protein phosphatase 1, regulatory subunit 3A 2.25147
MMP13 matrix metallopeptidase 13 2.25147
KIF12 kinesin family member 12 2.25147
FAM9B family with sequence similarity 9, member B 2.25147
CLCA2 chloride channel accessory 2 2.25147
KIF4B kinesin family member 4B 2.25147
NOL11 nucleolar protein 11 2.25147
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 2.25147
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 2.25147
NUTM2D NUT family member 2D 2.25147
TECRL trans-2,3-enoyl-CoA reductase-like 2.25147
ABCA10 ATP-binding cassette, sub-family A (ABC1), member 10 2.25147
BAG1 BCL2-associated athanogene 2.25147
FITM1 fat storage-inducing transmembrane protein 1 2.25147
DEFB134 defensin, beta 134 2.25147
CFAP54 cilia and flagella associated 54 2.25147
CERS4 ceramide synthase 4 2.23359
TNS4 tensin 4 2.22794
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 2.22794
DENND4C DENN/MADD domain containing 4C 2.22425
CFAP61 cilia and flagella associated protein 61 2.22425
HUNK hormonally up-regulated Neu-associated kinase 2.22425
DNAAF1 dynein, axonemal, assembly factor 1 2.22425
ACTL6A actin-like 6A 2.22425
SLC6A16 solute carrier family 6, member 16 2.22425
HYAL3 hyaluronoglucosaminidase 3 2.22425
CENPK centromere protein K 2.22425
SMKR1 small lysine-rich protein 1 2.22425
RNF34 ring finger protein 34, E3 ubiquitin protein ligase 2.22425
ZSCAN2 zinc finger and SCAN domain containing 2 2.22425
DEMA1 DPM1 ER membrane anchor 1 2.22388
ZNF736 zinc finger protein 736 2.22388
ORAI2 ORAI calcium release-activated calcium modulator 2 2.22233
OLFML1 olfactomedin-like 1 2.21804
SF3A3 splicing factor 3a, subunit 3, 60kDa 2.19091
CCDC138 coiled-coil domain containing 138 2.18715
FSCN1 fascin actin-bundling protein 1 2.16326
PPIL6 peptidylprolyl isomerase (cyclophilin)-like 6 2.15365
SNTA1 syntrophin, alpha 1 2.15365
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 2.14582
TMEM35B transmembrane protein 35B 2.13969
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 2.13969
TSKU tsukushi, small leucine rich proteoglycan 2.08972
PUM2 pumilio RNA-binding family member 2 2.08821
RAB39B RAB39B, member RAS oncogene family 2.08821
PALS2 protein associated with LIN7 2, MAGUK p55 family member 2.08661
PRKACB protein kinase, cAMP-dependent, catalytic, beta 2.07994
CCNL2 cyclin L2 2.07484
HNRNPM heterogeneous nuclear ribonucleoprotein M 2.06143
KIF9 kinesin family member 9 2.05999
GSG1L GSG1-like 2.04279
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 2.04097
SEPTIN6 septin 6 2.04096
JAKMIP2 janus kinase and microtubule interacting protein 2 2.02278
COL14A1 collagen, type XIV, alpha 1 2.01208
ENG endoglin 2.01208
BMPR1B bone morphogenetic protein receptor, type IB 2.01208
GSDME gasdermin E 2.00216

decreased expression

Symbol Name Standardized Value
ADPRH ADP-ribosylarginine hydrolase -2.29935
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa -2.29935
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family) -2.25147
MIER1 mesoderm induction early response 1, transcriptional regulator -2.25147
M1AP meiosis 1 associated protein -2.25147
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 -2.25147
BMP8A bone morphogenetic protein 8a -2.25147
TENT4B terminal nucleotidyltransferase 4B -2.25147
TSKS testis-specific serine kinase substrate -2.25147
CCDC167 coiled-coil domain containing 167 -2.25147
MSH4 mutS homolog 4 -2.25147
FOXO6 forkhead box O6 -2.25147
ADRA1D adrenoceptor alpha 1D -2.25147
FAM89A family with sequence similarity 89, member A -2.25147
KDM5C lysine (K)-specific demethylase 5C -2.25147
SOX21 SRY (sex determining region Y)-box 21 -2.25147
GMPR guanosine monophosphate reductase -2.25147
USP10 ubiquitin specific peptidase 10 -2.25147
ADAM15 ADAM metallopeptidase domain 15 -2.25147
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit -2.25147
LOC390937 Ets2 repressor factor-like -2.25147
NFYA nuclear transcription factor Y, alpha -2.25147
MBTD1 mbt domain containing 1 -2.25147
ADCK2 aarF domain containing kinase 2 -2.25147
WTIP Wilms tumor 1 interacting protein -2.25147
WDR49 WD repeat domain 49 -2.25147
PKP3 plakophilin 3 -2.25147
CFAP73 cilia and flagella associated protein 73 -2.25147
RPL7A ribosomal protein L7a -2.25147
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta -2.22433
PCP4L1 Purkinje cell protein 4 like 1 -2.22425
KYNU kynureninase -2.22425
ASIC4 acid sensing (proton gated) ion channel family member 4 -2.22425
DUXB double homeobox B -2.22425
PTGER3 prostaglandin E receptor 3 (subtype EP3) -2.22425
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 -2.22425
VSTM2L V-set and transmembrane domain containing 2 like -2.22425
KCNRG potassium channel regulator -2.22425
RIMBP2 RIMS binding protein 2 -2.22425
NPPC natriuretic peptide C -2.22425
RNF113B ring finger protein 113B -2.22425
NME5 NME/NM23 family member 5 -2.22425
MTMR11 myotubularin related protein 11 -2.22425
CSP2 CS pseudogene 2 -2.22425
RNF112 ring finger protein 112 -2.22425
VEGFD vascular endothelial growth factor D -2.22425
ERFE erythroferrone -2.22425
SV2C synaptic vesicle glycoprotein 2C -2.22425
CLRN1 clarin 1 -2.22425
TENT5D terminal nucleotidyltransferase 5D -2.22425
ARG1 arginase 1 -2.22425
RANBP3L RAN binding protein 3-like -2.22425
DRD3 dopamine receptor D3 -2.22425
ADAP1 ArfGAP with dual PH domains 1 -2.22425
PCDHAC1 protocadherin alpha subfamily C, 1 -2.22425
ARHGAP40 Rho GTPase activating protein 40 -2.22425
NPIPB15 nuclear pore complex interacting protein family, member B15 -2.22425
DNAH8 dynein, axonemal, heavy chain 8 -2.22425
ACRBP acrosin binding protein -2.22425
NLRP1 NLR family, pyrin domain containing 1 -2.22425
UNC5A unc-5 homolog A (C. elegans) -2.22425
TSPAN1 tetraspanin 1 -2.22425
PADI4 peptidyl arginine deiminase, type IV -2.22425
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 -2.22425
ADM5 adrenomedullin 5 (putative) -2.22425
ACKR3 atypical chemokine receptor 3 -2.22425
PTGDR prostaglandin D2 receptor (DP) -2.22425
DGKD diacylglycerol kinase, delta 130kDa -2.22425
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -2.22388
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide -2.20854
CHP2 calcineurin-like EF-hand protein 2 -2.18303
LOC112694756 uncharaterized LOC112694756 -2.16326
TMEM200C transmembrane protein 200C -2.16326
C17ORF100 chromosome 17 open reading frame 100 -2.16326
SLC67A1 solute carrier family 67 member 1 -2.16326
KCNMB4 potassium channel subfamily M regulatory beta subunit 4 -2.1527
MEF2D myocyte enhancer factor 2D -2.15058
ACAT2 acetyl-CoA acetyltransferase 2 -2.09826
STOX1 storkhead box 1 -2.0902
TMEM181 transmembrane protein 181 -2.08955
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 -2.07484
LMO1 LIM domain only 1 (rhombotin 1) -2.0732
COQ4 coenzyme Q4 -2.06721
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 -2.05862
HSBP1L1 heat shock factor binding protein 1-like 1 -2.05862
ARID3B AT rich interactive domain 3B (BRIGHT-like) -2.05862
YIPF4 Yip1 domain family, member 4 -2.04097
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) -2.04097
LRRN1 leucine rich repeat neuronal 1 -2.04097
UBP1 upstream binding protein 1 (LBP-1a) -2.02938
JAKMIP1 janus kinase and microtubule interacting protein 1 -2.01208
ACSF3 acyl-CoA synthetase family member 3 -2.01208
OR56A1 olfactory receptor, family 56, subfamily A, member 1 -2.01208
AMN1 antagonist of mitotic exit network 1 homolog (S. cerevisiae) -2.01208