| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | phosphogluconate dehydrogenase|6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015] (NCBI Entrez Gene Database, 5226) |
| External Link | https://ncbi.nlm.nih.gov/gene/5226 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the PGD gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0190772 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0117565 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.0114066 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0110913 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00996704 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.00981492 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00971247 |
| CTSH | cathepsin H | 0.0093394 |
| XBP1 | X-box binding protein 1 | 0.0092438 |
| GSTT1 | glutathione S-transferase theta 1 | 0.00897644 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.00880063 |
| VEGFA | vascular endothelial growth factor A | 0.00879426 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00843159 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0081625 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.00795132 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0079338 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00772969 |
| JAG1 | jagged 1 | 0.0075948 |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) | 0.00734147 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | 0.00725084 |
| ASPN | asporin | 0.00704892 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00703981 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.00669283 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 | 0.00667315 |
| PLN | phospholamban | 0.00665204 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 0.00665 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.00656332 |
| XPOT | exportin, tRNA | 0.00654025 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00648477 |
| BLNK | B-cell linker | 0.00646054 |
| MPST | mercaptopyruvate sulfurtransferase | 0.00642544 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00641492 |
| ATF4 | activating transcription factor 4 | 0.00641232 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00638995 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00635707 |
| CANX | calnexin | 0.00633905 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | 0.00633756 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 0.00633689 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.00633554 |
| RPL14 | ribosomal protein L14 | 0.00633317 |
| YBX3 | Y box binding protein 3 | 0.00632544 |
| MPZL2 | myelin protein zero-like 2 | 0.0062966 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.00628827 |
| RGCC | regulator of cell cycle | 0.006287 |
| MGP | matrix Gla protein | 0.00626516 |
| CBS | cystathionine-beta-synthase | 0.00626202 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.00624535 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.00616557 |
| CRLF1 | cytokine receptor-like factor 1 | 0.0061587 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00613305 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00609465 |
| BMP2 | bone morphogenetic protein 2 | 0.00607844 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | 0.00604482 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00604318 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | 0.00603926 |
| GSDME | gasdermin E | 0.00603657 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.00602854 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.00602467 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.00601944 |
| PER2 | period circadian clock 2 | 0.00597637 |
| RAB25 | RAB25, member RAS oncogene family | 0.00591884 |
| GSAP | gamma-secretase activating protein | 0.00591262 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00588481 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.00584134 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | 0.00583128 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00581239 |
| ZBTB35 | zinc finger and BTB domain containing 35 | 0.00579139 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0057812 |
| C6ORF48 | chromosome 6 open reading frame 48 | 0.0057735 |
| CNTN1 | contactin 1 | 0.00577218 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00572624 |
| MT1H | metallothionein 1H | 0.00572573 |
| RPL36 | ribosomal protein L36 | 0.00571285 |
| CD99 | CD99 molecule | 0.00567823 |
| TSC22D3 | TSC22 domain family, member 3 | 0.00566474 |
| CCND2 | cyclin D2 | 0.00564619 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00563603 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.00562555 |
| SORBS3 | sorbin and SH3 domain containing 3 | 0.00561106 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.00560072 |
| PDE1A | phosphodiesterase 1A, calmodulin-dependent | 0.00559028 |
| HOPX | HOP homeobox | 0.00558858 |
| PLS3 | plastin 3 | 0.00556903 |
| MT1F | metallothionein 1F | 0.00554898 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | 0.00553785 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00552906 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.00552284 |
| VSNL1 | visinin-like 1 | 0.00550231 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | 0.00546108 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00544954 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00544348 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00543229 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.00541498 |
| TRIM22 | tripartite motif containing 22 | 0.00539455 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | 0.00537429 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.00533676 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.00531897 |
| ITGB4 | integrin, beta 4 | 0.00531407 |
| CPNE1 | copine I | 0.00530495 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | 0.00529699 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.00528124 |
| KLK10 | kallikrein-related peptidase 10 | 0.0052802 |
| MAOA | monoamine oxidase A | 0.00527688 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00526931 |
| PRDX2 | peroxiredoxin 2 | 0.00523573 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00522476 |
| ITGA6 | integrin, alpha 6 | 0.00521032 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.00520957 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.00518739 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.00516885 |
| SATB2 | SATB homeobox 2 | 0.00516713 |
| THBS2 | thrombospondin 2 | 0.00515834 |
| ELANE | elastase, neutrophil expressed | 0.00514058 |
| SFTPB | surfactant protein B | 0.00514033 |
| PLA1A | phospholipase A1 member A | 0.00511602 |
| PHGDH | phosphoglycerate dehydrogenase | 0.00511542 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.00510749 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | 0.00509806 |
| EMP1 | epithelial membrane protein 1 | 0.0050784 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.00507292 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.00505355 |
| CCL21 | chemokine (C-C motif) ligand 21 | 0.00505113 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | 0.00505105 |
| APOB | apolipoprotein B | 0.00503399 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | 0.00502676 |
| CD200 | CD200 molecule | 0.00502092 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.004994 |
| ATP5F1D | ATP synthase F1 subunit delta | 0.00498104 |
| MST1 | macrophage stimulating 1 | 0.00496666 |
| HDLBP | high density lipoprotein binding protein | 0.00496487 |
| FAXDC2 | fatty acid hydroxylase domain containing 2 | 0.00493197 |
| MT1E | metallothionein 1E | 0.0049271 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | 0.00492709 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00491847 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | 0.00490885 |
| HYOU1 | hypoxia up-regulated 1 | 0.00490736 |
| FLNA | filamin A, alpha | 0.00490156 |
| APOD | apolipoprotein D | 0.00489995 |
| C4BPA | complement component 4 binding protein, alpha | 0.00489934 |
| LHFP | lipoma HMGIC fusion partner | 0.00489419 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0048887 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00488484 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00487903 |
| CLIP3 | CAP-GLY domain containing linker protein 3 | 0.00486981 |
| MID1IP1 | MID1 interacting protein 1 | 0.00486043 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00485234 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa | 0.00484141 |
| NIPSNAP2 | nipsnap homolog 2 | 0.00479994 |
| CAPG | capping protein (actin filament), gelsolin-like | 0.00479968 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.00475471 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00474238 |
| MT1G | metallothionein 1G | 0.00473801 |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 | 0.00472643 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 | 0.00472465 |
| TPST2 | tyrosylprotein sulfotransferase 2 | 0.00471895 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.004708 |
| G0S2 | G0/G1 switch 2 | 0.00470774 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | 0.00470612 |
| WFDC1 | WAP four-disulfide core domain 1 | 0.00470409 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | 0.00470302 |
| FST | follistatin | 0.0047023 |
| TSPAN1 | tetraspanin 1 | 0.00470213 |
| A2M | alpha-2-macroglobulin | 0.00470095 |
| APOC2 | apolipoprotein C-II | 0.00469838 |
| GDF15 | growth differentiation factor 15 | 0.00469536 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.00468978 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.00468845 |
| EREG | epiregulin | 0.00468567 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00466555 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0046562 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 0.00465418 |
| AHSG | alpha-2-HS-glycoprotein | 0.00463718 |
| AHCYL1 | adenosylhomocysteinase-like 1 | 0.00463473 |
| ZFAND1 | zinc finger, AN1-type domain 1 | 0.00463452 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.00462376 |
| CHN2 | chimerin 2 | 0.00462338 |
| AREG | amphiregulin | 0.00461454 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 0.00461428 |
| ASPH | aspartate beta-hydroxylase | 0.00461373 |
| EPAS1 | endothelial PAS domain protein 1 | 0.00459663 |
| TNS1 | tensin 1 | 0.00459629 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00459429 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.00458962 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | 0.00457405 |
| GRB10 | growth factor receptor-bound protein 10 | 0.00456039 |
| H1-0 | H1.0 linker histone | 0.00455648 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00452278 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | 0.00452237 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.00452142 |
| ARG2 | arginase 2 | 0.00452089 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.00450572 |
| RASA1 | RAS p21 protein activator (GTPase activating protein) 1 | 0.00448973 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00448726 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | 0.00447991 |
| GTPBP8 | GTP-binding protein 8 (putative) | 0.00447537 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | 0.00447409 |
| TMEM63A | transmembrane protein 63A | 0.0044384 |
| APOM | apolipoprotein M | 0.00441939 |
| PRNP | prion protein | 0.0043941 |
| TLCD3A | TLC domain containing 3A | 0.00439174 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | 0.00439108 |
| LETMD1 | LETM1 domain containing 1 | 0.00439013 |
| S100A6 | S100 calcium binding protein A6 | 0.00438483 |
| MFAP5 | microfibrillar associated protein 5 | 0.00438021 |
| NPTXR | neuronal pentraxin receptor | 0.00437348 |
| NOP53 | NOP53 ribosome biogenesis factor | 0.00436992 |
| PLXNB1 | plexin B1 | 0.00436939 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.00436705 |
| RSL24D1 | ribosomal L24 domain containing 1 | 0.00435848 |
| FABP3 | fatty acid binding protein 3, muscle and heart | 0.00435343 |
| EIF3F | eukaryotic translation initiation factor 3, subunit F | 0.0043314 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 0.00432673 |
| RNF19B | ring finger protein 19B | 0.00432421 |
| LAMA3 | laminin, alpha 3 | 0.00432141 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.00430362 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | 0.00430182 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.00429634 |
| CPQ | carboxypeptidase Q | 0.00429458 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.00429295 |
| REG1A | regenerating islet-derived 1 alpha | 0.00429247 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.00428894 |
| ASS1 | argininosuccinate synthase 1 | 0.00428086 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.00427458 |
| SMTN | smoothelin | 0.0042695 |
| FILIP1L | filamin A interacting protein 1-like | 0.0042688 |
| GOLGA8A | golgin A8 family, member A | 0.00426788 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.00426361 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.00425606 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.00424941 |
| MSN | moesin | 0.0042491 |
| COL5A2 | collagen, type V, alpha 2 | 0.00424098 |
| USP25 | ubiquitin specific peptidase 25 | 0.00423283 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.00421811 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | 0.00421606 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.00421606 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00420908 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.0041968 |
| INSR | insulin receptor | 0.0041957 |
| CLIC4 | chloride intracellular channel 4 | 0.00419517 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00418169 |
| SLC16A6 | solute carrier family 16, member 6 | 0.0041662 |
| GALE | UDP-galactose-4-epimerase | 0.00416111 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | 0.00415684 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00414996 |
| ADRB2 | adrenoceptor beta 2, surface | 0.00414883 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 0.00414628 |
| PILRB | paired immunoglobin-like type 2 receptor beta | 0.00414425 |
| CFD | complement factor D (adipsin) | 0.00414295 |
| CHRDL1 | chordin-like 1 | 0.00413882 |
| FGF9 | fibroblast growth factor 9 | 0.00413831 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA1A | heat shock 70kDa protein 1A | -0.0168589 |
| XIC | X chromosome inactivation center | -0.0142495 |
| S100A8 | S100 calcium binding protein A8 | -0.0112073 |
| MMD | monocyte to macrophage differentiation-associated | -0.0105943 |
| TSPAN13 | tetraspanin 13 | -0.00957674 |
| RPA3 | replication protein A3, 14kDa | -0.00928055 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00880582 |
| KYNU | kynureninase | -0.00876902 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00863101 |
| CA12 | carbonic anhydrase XII | -0.00834788 |
| MAP7 | microtubule-associated protein 7 | -0.00833804 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.00814473 |
| HSPA2 | heat shock 70kDa protein 2 | -0.00802435 |
| STK10 | serine/threonine kinase 10 | -0.00789966 |
| GCH1 | GTP cyclohydrolase 1 | -0.00773086 |
| S100A9 | S100 calcium binding protein A9 | -0.00768464 |
| BST2 | bone marrow stromal cell antigen 2 | -0.00760476 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00759981 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00759165 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.0074781 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | -0.00739603 |
| LUM | lumican | -0.00739035 |
| NR0B1 | nuclear receptor subfamily 0, group B, member 1 | -0.00714462 |
| CLGN | calmegin | -0.00712506 |
| PEG10 | paternally expressed 10 | -0.00710881 |
| PLIN2 | perilipin 2 | -0.00709723 |
| TMSB15A | thymosin beta 15a | -0.00700799 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.00695843 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.00695807 |
| NVL | nuclear VCP-like | -0.00687983 |
| MCM10 | minichromosome maintenance complex component 10 | -0.0068252 |
| SPP1 | secreted phosphoprotein 1 | -0.00680638 |
| LYPD1 | LY6/PLAUR domain containing 1 | -0.00670774 |
| DACH1 | dachshund family transcription factor 1 | -0.00669008 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | -0.00665832 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -0.00662866 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00655633 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.00655484 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | -0.00655196 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.00654023 |
| TWIST1 | twist family bHLH transcription factor 1 | -0.00650564 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00643258 |
| ADGRE1 | adhesion G protein-coupled receptor E1 | -0.00636935 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -0.00635483 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) | -0.0063403 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | -0.00629603 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00629468 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.00628404 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.0062653 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | -0.0062435 |
| COMMD3 | COMM domain containing 3 | -0.00623885 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.00615038 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00614445 |
| AUTS2 | autism susceptibility candidate 2 | -0.0061083 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.0060517 |
| TTK | TTK protein kinase | -0.00601334 |
| HOXB7 | homeobox B7 | -0.00600816 |
| LEPROTL1 | leptin receptor overlapping transcript-like 1 | -0.00597702 |
| IL15 | interleukin 15 | -0.00596814 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00596161 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | -0.00590397 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 | -0.00586501 |
| TDO2 | tryptophan 2,3-dioxygenase | -0.0058638 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00586212 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00579 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00578282 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00575775 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00575169 |
| CLC | Charcot-Leyden crystal galectin | -0.005687 |
| CD8A | CD8a molecule | -0.00568094 |
| CSRP2 | cysteine and glycine-rich protein 2 | -0.00562577 |
| SOX11 | SRY (sex determining region Y)-box 11 | -0.00560788 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00554024 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00553631 |
| COCH | cochlin | -0.00550579 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.0054979 |
| NSL1 | NSL1, MIS12 kinetochore complex component | -0.00549185 |
| CCNE2 | cyclin E2 | -0.0054582 |
| NLRP2 | NLR family, pyrin domain containing 2 | -0.00545621 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00544402 |
| SRGN | serglycin | -0.00540973 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | -0.00540074 |
| FADD | Fas (TNFRSF6)-associated via death domain | -0.00537607 |
| MCL1 | myeloid cell leukemia 1 | -0.00536698 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0053551 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.00532129 |
| TMEM14A | transmembrane protein 14A | -0.0053063 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | -0.00529188 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00527664 |
| RUNX3 | runt-related transcription factor 3 | -0.00526927 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.00525351 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | -0.00522709 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | -0.00519996 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.0051783 |
| MAGEA3 | melanoma antigen family A3 | -0.00513743 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | -0.00511419 |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa | -0.00511156 |
| PCLAF | PCNA clamp associated factor | -0.00510641 |
| PLXNC1 | plexin C1 | -0.00510376 |
| NENF | neudesin neurotrophic factor | -0.00509166 |
| EMP2 | epithelial membrane protein 2 | -0.00508895 |
| PBK | PDZ binding kinase | -0.00507581 |
| SYT1 | synaptotagmin I | -0.00505835 |
| JUNB | jun B proto-oncogene | -0.00505334 |
| C5ORF30 | chromosome 5 open reading frame 30 | -0.00505033 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.00502872 |
| NEFH | neurofilament, heavy polypeptide | -0.00501775 |
| NCAPG | non-SMC condensin I complex, subunit G | -0.00501169 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | -0.00500422 |
| RNASEH2A | ribonuclease H2, subunit A | -0.00499499 |
| HSPA14 | heat shock 70kDa protein 14 | -0.00498731 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00495697 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00495148 |
| AURKB | aurora kinase B | -0.00494334 |
| SNRPG | small nuclear ribonucleoprotein polypeptide G | -0.00493884 |
| CD1E | CD1e molecule | -0.00493617 |
| SLC25A44 | solute carrier family 25, member 44 | -0.00491284 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.00487912 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | -0.00487191 |
| BCL2A1 | BCL2-related protein A1 | -0.00485446 |
| POPDC3 | popeye domain containing 3 | -0.00481713 |
| CENPE | centromere protein E, 312kDa | -0.00481328 |
| CENPU | centromere protein U | -0.00481222 |
| THAP11 | THAP domain containing 11 | -0.00480725 |
| CYB5A | cytochrome b5 type A (microsomal) | -0.00480291 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.004792 |
| CALML5 | calmodulin-like 5 | -0.004767 |
| MLF1 | myeloid leukemia factor 1 | -0.00476658 |
| SELPLG | selectin P ligand | -0.00476468 |
| IL32 | interleukin 32 | -0.00474738 |
| IFI44 | interferon-induced protein 44 | -0.00474301 |
| ADI1 | acireductone dioxygenase 1 | -0.0047178 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) | -0.00471272 |
| CTSS | cathepsin S | -0.00470795 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | -0.00469801 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0046946 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.00466019 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | -0.00463674 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.00463651 |
| MMP12 | matrix metallopeptidase 12 | -0.00462891 |
| ORMDL2 | ORMDL sphingolipid biosynthesis regulator 2 | -0.0046147 |
| TYROBP | TYRO protein tyrosine kinase binding protein | -0.00460435 |
| MMP10 | matrix metallopeptidase 10 | -0.00459248 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0045768 |
| BID | BH3 interacting domain death agonist | -0.00457425 |
| HOXA5 | homeobox A5 | -0.00457386 |
| ARF3 | ADP-ribosylation factor 3 | -0.00456933 |
| SUSD4 | sushi domain containing 4 | -0.00456705 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.00453629 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00453611 |
| PLBD1 | phospholipase B domain containing 1 | -0.00453457 |
| WT1 | Wilms tumor 1 | -0.00451571 |
| PLAT | plasminogen activator, tissue | -0.00451427 |
| TUBA1A | tubulin, alpha 1a | -0.00450736 |
| BEX4 | brain expressed, X-linked 4 | -0.00449341 |
| ATG101 | autophagy related 101 | -0.00449119 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0044891 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.00448207 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0044762 |
| SMAD6 | SMAD family member 6 | -0.00446803 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00446429 |
| RRM2 | ribonucleotide reductase M2 | -0.00446052 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | -0.00445908 |
| SHCBP1 | SHC SH2-domain binding protein 1 | -0.00444766 |
| UGT8 | UDP glycosyltransferase 8 | -0.00444161 |
| RTN2 | reticulon 2 | -0.00442294 |
| KIF23 | kinesin family member 23 | -0.00440966 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00440761 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | -0.00440439 |
| ADM | adrenomedullin | -0.00440405 |
| PTGES | prostaglandin E synthase | -0.0043972 |
| IL18 | interleukin 18 | -0.00438752 |
| APOBEC3A | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A | -0.00438608 |
| EFHD1 | EF-hand domain family, member D1 | -0.00438361 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00438127 |
| CCNE1 | cyclin E1 | -0.00436425 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | -0.0043631 |
| CRIPT | cysteine-rich PDZ-binding protein | -0.00436184 |
| IL2RG | interleukin 2 receptor, gamma | -0.00435165 |
| FAM171A1 | family with sequence similarity 171, member A1 | -0.00435105 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | -0.00435083 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | -0.00434265 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.00433891 |
| MEN1 | multiple endocrine neoplasia I | -0.00432194 |
| SNX11 | sorting nexin 11 | -0.00432169 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00432098 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.00431614 |
| DAPK1 | death-associated protein kinase 1 | -0.00431465 |
| ZWILCH | zwilch kinetochore protein | -0.00429822 |
| TKTL1 | transketolase-like 1 | -0.00429669 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | -0.00429482 |
| ZW10 | zw10 kinetochore protein | -0.00429304 |
| CLCA1 | chloride channel accessory 1 | -0.00429056 |
| PIP | prolactin-induced protein | -0.00428944 |
| FASTKD5 | FAST kinase domains 5 | -0.00428332 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 | -0.00428133 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0042667 |
| RB1 | retinoblastoma 1 | -0.00426103 |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | -0.00425197 |
| NDC80 | NDC80 kinetochore complex component | -0.00424768 |
| FPR1 | formyl peptide receptor 1 | -0.00423978 |
| ASF1B | anti-silencing function 1B histone chaperone | -0.00423909 |
| CSF1R | colony stimulating factor 1 receptor | -0.00422449 |
| DCK | deoxycytidine kinase | -0.00422204 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.00421023 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D | -0.00420518 |
| SLC25A46 | solute carrier family 25, member 46 | -0.00418832 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00418325 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.00418213 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -0.0041814 |
| FBXO11 | F-box protein 11 | -0.0041775 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -0.00417096 |
| CDC123 | cell division cycle 123 | -0.00416814 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.0041607 |
| HMOX1 | heme oxygenase 1 | -0.00415561 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | -0.00414693 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 | -0.00413803 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | -0.00413524 |
| SYNPO | synaptopodin | -0.00412217 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.00412085 |
| IL7R | interleukin 7 receptor | -0.00411267 |
| BAG3 | BCL2-associated athanogene 3 | -0.00409717 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -0.00409594 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | -0.00409193 |
| TYMP | thymidine phosphorylase | -0.00408443 |
| CDK19 | cyclin-dependent kinase 19 | -0.00408199 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -0.0040735 |
| HSBP1 | heat shock factor binding protein 1 | -0.00407241 |
| MEIS2 | Meis homeobox 2 | -0.00406672 |
| IL1R2 | interleukin 1 receptor, type II | -0.00406293 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00405797 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -0.00404711 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.00404598 |
| TOR1A | torsin family 1, member A (torsin A) | -0.00403386 |
| RAD51 | RAD51 recombinase | -0.00402337 |
| KIF20A | kinesin family member 20A | -0.00402289 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -0.00401164 |
| RNF144A | ring finger protein 144A | -0.00401162 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | -0.00400881 |
| ATP5F1C | ATP synthase F1 subunit gamma | -0.00400632 |
| HOXB13 | homeobox B13 | -0.00400373 |
| MMP9 | matrix metallopeptidase 9 | -0.00400063 |
| HMGN5 | high mobility group nucleosome binding domain 5 | -0.00399806 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | -0.00399712 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | -0.00399658 |
| CCR7 | chemokine (C-C motif) receptor 7 | -0.00399028 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | -0.00398346 |
| MAL | mal, T-cell differentiation protein | -0.00397892 |
| PARPBP | PARP1 binding protein | -0.00396983 |
