| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | phosphoglycerate kinase 1|The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome. [provided by RefSeq, Jan 2014] (NCBI Entrez Gene Database, 5230) |
| External Link | https://ncbi.nlm.nih.gov/gene/5230 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the PGK1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GNAS | GNAS complex locus | 0.0180298 |
| KIAA0100 | KIAA0100 | 0.013702 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0127475 |
| PEG10 | paternally expressed 10 | 0.0125282 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.0117581 |
| ITM2A | integral membrane protein 2A | 0.0116993 |
| GPC3 | glypican 3 | 0.0114503 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0108898 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0108195 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0105783 |
| MGP | matrix Gla protein | 0.0102284 |
| MAGEA3 | melanoma antigen family A3 | 0.00994253 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00935199 |
| METTL7A | methyltransferase like 7A | 0.00919851 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00906031 |
| GOLGA8A | golgin A8 family, member A | 0.00884116 |
| TCF4 | transcription factor 4 | 0.00882115 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00877237 |
| EDN3 | endothelin 3 | 0.00873929 |
| BEX1 | brain expressed, X-linked 1 | 0.00872996 |
| CRABP1 | cellular retinoic acid binding protein 1 | 0.00872957 |
| CADM1 | cell adhesion molecule 1 | 0.00871181 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00866736 |
| CPE | carboxypeptidase E | 0.00858494 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | 0.00843518 |
| PRKD3 | protein kinase D3 | 0.00843504 |
| DPP8 | dipeptidyl-peptidase 8 | 0.00843022 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | 0.00836506 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00834724 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00822108 |
| NFIB | nuclear factor I/B | 0.0081749 |
| RELN | reelin | 0.00812256 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00812147 |
| COL9A3 | collagen, type IX, alpha 3 | 0.00801737 |
| PURA | purine-rich element binding protein A | 0.00779815 |
| PCDH9 | protocadherin 9 | 0.00779016 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00775459 |
| MAGEA12 | melanoma antigen family A12 | 0.00770067 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00766461 |
| EMP2 | epithelial membrane protein 2 | 0.00766192 |
| MT1E | metallothionein 1E | 0.00756222 |
| OLFM1 | olfactomedin 1 | 0.00747481 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00746296 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00745994 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.00743907 |
| FAM222B | family with sequence similarity 222, member B | 0.00742941 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 0.00732557 |
| RGS5 | regulator of G-protein signaling 5 | 0.00728007 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.00726307 |
| FABP7 | fatty acid binding protein 7, brain | 0.00722862 |
| C14ORF132 | chromosome 14 open reading frame 132 | 0.00721379 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00719756 |
| COL6A1 | collagen, type VI, alpha 1 | 0.00718129 |
| FHL1 | four and a half LIM domains 1 | 0.00713879 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00707718 |
| ARHGAP44 | Rho GTPase activating protein 44 | 0.00707063 |
| CHPT1 | choline phosphotransferase 1 | 0.00704083 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00682902 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.00680764 |
| MT1M | metallothionein 1M | 0.00679873 |
| FKBP5 | FK506 binding protein 5 | 0.00679204 |
| DLD | dihydrolipoamide dehydrogenase | 0.00677968 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.0067658 |
| THBS4 | thrombospondin 4 | 0.00669234 |
| MT1HL1 | metallothionein 1H-like 1 | 0.0066008 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | 0.0065988 |
| SLC35G2 | solute carrier family 35, member G2 | 0.00659668 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00656215 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00647714 |
| USP34 | ubiquitin specific peptidase 34 | 0.00647604 |
| GLUL | glutamate-ammonia ligase | 0.00646489 |
| ZBTB16 | zinc finger and BTB domain containing 16 | 0.00645478 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.00643312 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | 0.00637119 |
| PDE10A | phosphodiesterase 10A | 0.006355 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | 0.00634476 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | 0.0063307 |
| MFAP4 | microfibrillar-associated protein 4 | 0.00630315 |
| MAB21L1 | mab-21-like 1 (C. elegans) | 0.0062702 |
| CCP110 | centriolar coiled coil protein 110kDa | 0.00626548 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | 0.00625516 |
| ACACB | acetyl-CoA carboxylase beta | 0.00624819 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.00624574 |
| NKTR | natural killer cell triggering receptor | 0.00624061 |
| DCLRE1C | DNA cross-link repair 1C | 0.00623566 |
| AHNAK | AHNAK nucleoprotein | 0.00622851 |
| H1-10 | H1.10 linker histone | 0.00621103 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00620829 |
| MT1H | metallothionein 1H | 0.00615493 |
| SGCE | sarcoglycan, epsilon | 0.00615441 |
| GLTP | glycolipid transfer protein | 0.00611969 |
| MAGEA1 | melanoma antigen family A1 | 0.00611831 |
| PGBD5 | piggyBac transposable element derived 5 | 0.00609602 |
| ZNF652 | zinc finger protein 652 | 0.00607987 |
| TSPAN7 | tetraspanin 7 | 0.00606716 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.00600793 |
| PAX6 | paired box 6 | 0.00600644 |
| EMP1 | epithelial membrane protein 1 | 0.00600641 |
| ASPH | aspartate beta-hydroxylase | 0.00599975 |
| UBXN7 | UBX domain protein 7 | 0.00599769 |
| MEOX2 | mesenchyme homeobox 2 | 0.00598771 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00597115 |
| ZBTB35 | zinc finger and BTB domain containing 35 | 0.00597103 |
| CA4 | carbonic anhydrase IV | 0.00594086 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | 0.00590348 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.00587764 |
| TSC22D1 | TSC22 domain family, member 1 | 0.005867 |
| DVL3 | dishevelled segment polarity protein 3 | 0.00586309 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | 0.00583934 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0058238 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0058065 |
| AHCYL1 | adenosylhomocysteinase-like 1 | 0.00579375 |
| MBD2 | methyl-CpG binding domain protein 2 | 0.00575976 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00575017 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.0057392 |
| MT2A | metallothionein 2A | 0.00573794 |
| CD70 | CD70 molecule | 0.00572281 |
| KIF20A | kinesin family member 20A | 0.00571448 |
| CREBZF | CREB/ATF bZIP transcription factor | 0.00570571 |
| DCHS1 | dachsous cadherin-related 1 | 0.00570251 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00569699 |
| PFN2 | profilin 2 | 0.00569107 |
| TNNC1 | troponin C type 1 (slow) | 0.00568366 |
| SDC2 | syndecan 2 | 0.00566501 |
| HMGB1 | high mobility group box 1 | 0.00565788 |
| RIOX2 | ribosomal oxygenase 2 | 0.00564605 |
| CDC42 | cell division cycle 42 | 0.0056371 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | 0.00563135 |
| SUSD4 | sushi domain containing 4 | 0.00560764 |
| C2ORF68 | chromosome 2 open reading frame 68 | 0.00560449 |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) | 0.00560329 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00560095 |
| NOTCH2NL | notch 2 N-terminal like | 0.00560073 |
| GUCA2A | guanylate cyclase activator 2A (guanylin) | 0.00559 |
| PDAP1 | PDGFA associated protein 1 | 0.00557015 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00556775 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.0055501 |
| CLCA4 | chloride channel accessory 4 | 0.00551944 |
| MSH2 | mutS homolog 2 | 0.00550907 |
| MEX3D | mex-3 RNA binding family member D | 0.00550069 |
| PRRX1 | paired related homeobox 1 | 0.00548931 |
| HIRA | histone cell cycle regulator | 0.00548585 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.00548268 |
| RASA4 | RAS p21 protein activator 4 | 0.00548158 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.00547492 |
| CDC123 | cell division cycle 123 | 0.00547385 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.00546684 |
| PGD | phosphogluconate dehydrogenase | 0.00546318 |
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 | 0.00545981 |
| TENM3 | teneurin transmembrane protein 3 | 0.00545927 |
| CUX1 | cut-like homeobox 1 | 0.00545481 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 | 0.00544982 |
| GRAMD1B | GRAM domain containing 1B | 0.00543759 |
| CS | citrate synthase | 0.00543443 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.00542905 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.00542763 |
| ATP9A | ATPase, class II, type 9A | 0.00539498 |
| CDV3 | CDV3 homolog (mouse) | 0.00539493 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.00538516 |
| CDA | cytidine deaminase | 0.00537785 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited | 0.0053704 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.00536769 |
| ADD3 | adducin 3 (gamma) | 0.00536285 |
| ARMCX3 | armadillo repeat containing, X-linked 3 | 0.0053534 |
| NFIC | nuclear factor I/C (CCAAT-binding transcription factor) | 0.00533425 |
| CHGB | chromogranin B | 0.00532724 |
| PROM1 | prominin 1 | 0.00531308 |
| SEPHS1 | selenophosphate synthetase 1 | 0.00530452 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00529372 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.00528988 |
| CAPRIN1 | cell cycle associated protein 1 | 0.00528334 |
| USP6NL | USP6 N-terminal like | 0.00528201 |
| ZNF281 | zinc finger protein 281 | 0.00526808 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | 0.00526664 |
| PTCH1 | patched 1 | 0.00524718 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.00524177 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.00522885 |
| MGLL | monoglyceride lipase | 0.00521927 |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 | 0.00521867 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.00521594 |
| TFDP1 | transcription factor Dp-1 | 0.00520624 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.00520538 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) | 0.00519858 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | 0.00519098 |
| LAMA2 | laminin, alpha 2 | 0.00518341 |
| ADK | adenosine kinase | 0.00518152 |
| PCOLCE | procollagen C-endopeptidase enhancer | 0.00517028 |
| MECP2 | methyl CpG binding protein 2 | 0.00516719 |
| RTN2 | reticulon 2 | 0.00515672 |
| OPHN1 | oligophrenin 1 | 0.00515202 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | 0.00514713 |
| PLCG1 | phospholipase C, gamma 1 | 0.00513725 |
| CRYAB | crystallin, alpha B | 0.00513357 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | 0.00510136 |
| BST2 | bone marrow stromal cell antigen 2 | 0.00507865 |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) | 0.00507452 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00505742 |
| PRKCA | protein kinase C, alpha | 0.00505081 |
| ACAT1 | acetyl-CoA acetyltransferase 1 | 0.00504932 |
| LOX | lysyl oxidase | 0.00504517 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | 0.00504298 |
| TBC1D2B | TBC1 domain family, member 2B | 0.00503524 |
| GRK5 | G protein-coupled receptor kinase 5 | 0.00503348 |
| ADAM22 | ADAM metallopeptidase domain 22 | 0.00501527 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.00501416 |
| ZMYND11 | zinc finger, MYND-type containing 11 | 0.00500535 |
| CSNK1G2 | casein kinase 1, gamma 2 | 0.00500338 |
| CASD1 | CAS1 domain containing 1 | 0.00499195 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00499099 |
| VPS35 | vacuolar protein sorting 35 homolog (S. cerevisiae) | 0.00499018 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00498638 |
| WASF2 | WAS protein family, member 2 | 0.00498138 |
| ZNF106 | zinc finger protein 106 | 0.00497618 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.00496789 |
| ABHD17A | abhydrolase domain containing 17A | 0.00496102 |
| HK2 | hexokinase 2 | 0.00495801 |
| NOTCH2 | notch 2 | 0.00495092 |
| RAB1A | RAB1A, member RAS oncogene family | 0.00494694 |
| MAP1B | microtubule-associated protein 1B | 0.00494406 |
| DLAT | dihydrolipoamide S-acetyltransferase | 0.00493526 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.00493446 |
| KLF9 | Kruppel-like factor 9 | 0.00492645 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 | 0.00492077 |
| NRCAM | neuronal cell adhesion molecule | 0.00491473 |
| TNPO3 | transportin 3 | 0.00491045 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00489079 |
| STMN2 | stathmin 2 | 0.00488891 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00488611 |
| FMOD | fibromodulin | 0.00488497 |
| PSRC1 | proline/serine-rich coiled-coil 1 | 0.00488061 |
| KYNU | kynureninase | 0.00487649 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.00487203 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0048669 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | 0.00486506 |
| RBBP4 | retinoblastoma binding protein 4 | 0.00486029 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | 0.00485565 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00484158 |
| PHTF1 | putative homeodomain transcription factor 1 | 0.0048342 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha | 0.00483243 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.00483068 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.00481937 |
| FOCAD | focadhesin | 0.00481805 |
| CD320 | CD320 molecule | 0.004815 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.00479959 |
| PDHA1 | pyruvate dehydrogenase (lipoamide) alpha 1 | 0.00479736 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.00479608 |
| NES | nestin | 0.00477817 |
| KIF14 | kinesin family member 14 | 0.00477743 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | 0.00477371 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TOX3 | TOX high mobility group box family member 3 | -0.014518 |
| TUBB2A | tubulin, beta 2A class IIa | -0.0144086 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0129011 |
| PUF60 | poly-U binding splicing factor 60KDa | -0.0124133 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.0115877 |
| DIPK1A | divergent protein kinase domain 1A | -0.0108849 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.0108549 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.0106359 |
| WT1 | Wilms tumor 1 | -0.0105407 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.0104768 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0102609 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.010201 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.0101158 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00984129 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.00983332 |
| VEGFA | vascular endothelial growth factor A | -0.00982909 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00959148 |
| CSTA | cystatin A (stefin A) | -0.00956146 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | -0.00951255 |
| CTSH | cathepsin H | -0.00948354 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.0094668 |
| PXDC1 | PX domain containing 1 | -0.00945215 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00939462 |
| GRB7 | growth factor receptor-bound protein 7 | -0.00916939 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00915435 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.009121 |
| RNASE6 | ribonuclease, RNase A family, k6 | -0.00909117 |
| HBD | hemoglobin, delta | -0.00904416 |
| CA2 | carbonic anhydrase II | -0.00898319 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00893905 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | -0.00886755 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | -0.00884586 |
| HOXB2 | homeobox B2 | -0.00874685 |
| PLBD1 | phospholipase B domain containing 1 | -0.00865675 |
| HNMT | histamine N-methyltransferase | -0.00864427 |
| RNF167 | ring finger protein 167 | -0.00857867 |
| ACP3 | acid phosphatase 3 | -0.00857712 |
| EPCAM | epithelial cell adhesion molecule | -0.0085766 |
| XCL1 | chemokine (C motif) ligand 1 | -0.00857655 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.00853907 |
| AGTR1 | angiotensin II receptor, type 1 | -0.00853227 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00852901 |
| MSMB | microseminoprotein, beta- | -0.0084827 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00846922 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00842866 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00840705 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00839535 |
| GPR183 | G protein-coupled receptor 183 | -0.00818516 |
| GPR137B | G protein-coupled receptor 137B | -0.00816691 |
| ACP5 | acid phosphatase 5, tartrate resistant | -0.00813287 |
| TARP | TCR gamma alternate reading frame protein | -0.00813048 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.00803821 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | -0.00803687 |
| CRYM | crystallin, mu | -0.00800108 |
| SLC44A4 | solute carrier family 44, member 4 | -0.00796816 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.00795065 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.00779046 |
| F5 | coagulation factor V (proaccelerin, labile factor) | -0.00777135 |
| AMACR | alpha-methylacyl-CoA racemase | -0.00776693 |
| BCL2L1 | BCL2-like 1 | -0.0077484 |
| SLC17A3 | solute carrier family 17 (organic anion transporter), member 3 | -0.00771775 |
| AIF1 | allograft inflammatory factor 1 | -0.00770236 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 | -0.00769111 |
| FZD5 | frizzled class receptor 5 | -0.00763873 |
| DPP4 | dipeptidyl-peptidase 4 | -0.00762807 |
| NKX3-1 | NK3 homeobox 1 | -0.00757691 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | -0.00757375 |
| TMEM176B | transmembrane protein 176B | -0.0075158 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00751126 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 | -0.00749567 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A | -0.00742592 |
| IRF7 | interferon regulatory factor 7 | -0.00740705 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.00730563 |
| FRMD4B | FERM domain containing 4B | -0.00725287 |
| DAPK1 | death-associated protein kinase 1 | -0.0072521 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -0.00723903 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -0.00723141 |
| STK26 | serine/threonine protein kinase 26 | -0.00721616 |
| DSP | desmoplakin | -0.00721239 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | -0.00721188 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00717891 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.00716665 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.00716028 |
| PYCARD | PYD and CARD domain containing | -0.00715334 |
| KLK10 | kallikrein-related peptidase 10 | -0.00715086 |
| FPGS | folylpolyglutamate synthase | -0.00714743 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.00713332 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00710223 |
| EFNB2 | ephrin-B2 | -0.00705708 |
| XIC | X chromosome inactivation center | -0.00705403 |
| TUFT1 | tuftelin 1 | -0.00704217 |
| CALB1 | calbindin 1, 28kDa | -0.00702422 |
| SERINC5 | serine incorporator 5 | -0.00701977 |
| GMPR | guanosine monophosphate reductase | -0.00698314 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00697582 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -0.00693803 |
| SOCS1 | suppressor of cytokine signaling 1 | -0.00692623 |
| S100P | S100 calcium binding protein P | -0.006894 |
| CST1 | cystatin SN | -0.00688694 |
| IGSF6 | immunoglobulin superfamily, member 6 | -0.00684413 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00684288 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.00681895 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.00681368 |
| ALAS2 | 5'-aminolevulinate synthase 2 | -0.00680103 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | -0.0067906 |
| SLAMF1 | signaling lymphocytic activation molecule family member 1 | -0.00676226 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00675949 |
| TMEM176A | transmembrane protein 176A | -0.00674634 |
| LST1 | leukocyte specific transcript 1 | -0.00671907 |
| LY86 | lymphocyte antigen 86 | -0.0066953 |
| LIMK2 | LIM domain kinase 2 | -0.00669504 |
| HOXB6 | homeobox B6 | -0.00669306 |
| CYTIP | cytohesin 1 interacting protein | -0.0066898 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.00668771 |
| CYP4A11 | cytochrome P450, family 4, subfamily A, polypeptide 11 | -0.00668062 |
| NKG7 | natural killer cell granule protein 7 | -0.00666733 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.0066619 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00664361 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.00661272 |
| CD86 | CD86 molecule | -0.00658929 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.00658833 |
| FKBP9 | FK506 binding protein 9, 63 kDa | -0.00657876 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00657836 |
| CANT1 | calcium activated nucleotidase 1 | -0.00656593 |
| CLEC4A | C-type lectin domain family 4, member A | -0.0065477 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | -0.00652578 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00651936 |
| BPGM | 2,3-bisphosphoglycerate mutase | -0.00651437 |
| CTSV | cathepsin V | -0.00647656 |
| DUSP3 | dual specificity phosphatase 3 | -0.00646463 |
| CNN1 | calponin 1, basic, smooth muscle | -0.0064599 |
| CYB5A | cytochrome b5 type A (microsomal) | -0.00645732 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.00644799 |
| CD300A | CD300a molecule | -0.00641144 |
| TYROBP | TYRO protein tyrosine kinase binding protein | -0.00637588 |
| MLPH | melanophilin | -0.00633988 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -0.00632004 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00631435 |
| CD38 | CD38 molecule | -0.00629129 |
| KLK2 | kallikrein-related peptidase 2 | -0.00628291 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.00625983 |
| IER2 | immediate early response 2 | -0.0062567 |
| BLVRB | biliverdin reductase B | -0.00625334 |
| MIPEP | mitochondrial intermediate peptidase | -0.00624742 |
| LYZ | lysozyme | -0.00623152 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.00621089 |
| MPP1 | membrane protein, palmitoylated 1, 55kDa | -0.00619598 |
| TJP2 | tight junction protein 2 | -0.00617623 |
| GPX2 | glutathione peroxidase 2 | -0.00616168 |
| USP18 | ubiquitin specific peptidase 18 | -0.00615616 |
| KLF10 | Kruppel-like factor 10 | -0.00615523 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.00614541 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00614336 |
| RNF19B | ring finger protein 19B | -0.00612736 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog | -0.00610207 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | -0.00608577 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00606957 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.0060562 |
| NTS | neurotensin | -0.00605228 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.00603899 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | -0.00602417 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | -0.00602163 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | -0.00600843 |
| LY96 | lymphocyte antigen 96 | -0.00599916 |
| BHMT | betaine--homocysteine S-methyltransferase | -0.00599774 |
| AQP9 | aquaporin 9 | -0.00595846 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.00593749 |
| THBS1 | thrombospondin 1 | -0.00592136 |
| AHSP | alpha hemoglobin stabilizing protein | -0.00591284 |
| SELENBP1 | selenium binding protein 1 | -0.0058815 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | -0.00586367 |
| ETNK1 | ethanolamine kinase 1 | -0.00586177 |
| ZNF267 | zinc finger protein 267 | -0.00585817 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.00584851 |
| MYRF | myelin regulatory factor | -0.00583515 |
| PBLD | phenazine biosynthesis-like protein domain containing | -0.00582777 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 | -0.00580215 |
| CCR2 | chemokine (C-C motif) receptor 2 | -0.00579234 |
| MOSPD1 | motile sperm domain containing 1 | -0.00579009 |
| SH3YL1 | SH3 and SYLF domain containing 1 | -0.00578154 |
| GJB1 | gap junction protein, beta 1, 32kDa | -0.00577394 |
| LACTB2 | lactamase, beta 2 | -0.00576459 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | -0.00576406 |
| LGALS9 | lectin, galactoside-binding, soluble, 9 | -0.00576375 |
| C6ORF48 | chromosome 6 open reading frame 48 | -0.00575464 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00574824 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | -0.00574455 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa | -0.00572598 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0057157 |
| IRF9 | interferon regulatory factor 9 | -0.00571444 |
| AHR | aryl hydrocarbon receptor | -0.00569971 |
| CST7 | cystatin F (leukocystatin) | -0.00569733 |
| MARCKSL1 | MARCKS-like 1 | -0.00569384 |
| DIO1 | deiodinase, iodothyronine, type I | -0.00569086 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) | -0.0056785 |
| LY75 | lymphocyte antigen 75 | -0.00566826 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.00566399 |
| MRPS28 | mitochondrial ribosomal protein S28 | -0.00564892 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | -0.00564778 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00564609 |
| OSTM1 | osteopetrosis associated transmembrane protein 1 | -0.00564442 |
| GNLY | granulysin | -0.00564428 |
| RAB38 | RAB38, member RAS oncogene family | -0.00564037 |
| PCNA | proliferating cell nuclear antigen | -0.00563782 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | -0.00562463 |
| TSPAN1 | tetraspanin 1 | -0.00561566 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | -0.005613 |
| HIST1H2AC | histone cluster 1, H2ac | -0.00559856 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00559198 |
| KRT1 | keratin 1, type II | -0.00558243 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00557919 |
| EGR3 | early growth response 3 | -0.00557823 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.00557418 |
| SLAMF7 | SLAM family member 7 | -0.00557196 |
| MX2 | MX dynamin-like GTPase 2 | -0.00554221 |
| ZCCHC10 | zinc finger, CCHC domain containing 10 | -0.00553517 |
| HIST1H2BK | histone cluster 1, H2bk | -0.00553392 |
| GPC4 | glypican 4 | -0.00553325 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | -0.00552002 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | -0.00551945 |
| ZNF468 | zinc finger protein 468 | -0.00550634 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.00550219 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | -0.0054956 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00548887 |
| KLK3 | kallikrein-related peptidase 3 | -0.00547714 |
| SEPHS2 | selenophosphate synthetase 2 | -0.00545645 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00545538 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.00543749 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00543076 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00542332 |
| ADAP2 | ArfGAP with dual PH domains 2 | -0.00541866 |
| TFEC | transcription factor EC | -0.0054168 |
| FAAH | fatty acid amide hydrolase | -0.0054054 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.00539861 |
| SMTN | smoothelin | -0.00539476 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | -0.00539042 |
| TTC38 | tetratricopeptide repeat domain 38 | -0.00537723 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | -0.00537338 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | -0.00535878 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00535287 |
| YARS1 | tyrosyl-tRNA synthetase 1 | -0.00535211 |
| CLEC7A | C-type lectin domain family 7, member A | -0.00535053 |
| ACE2 | angiotensin I converting enzyme 2 | -0.00534467 |
| PLS1 | plastin 1 | -0.00534274 |
| GIMAP4 | GTPase, IMAP family member 4 | -0.00531108 |
| PDGFC | platelet derived growth factor C | -0.00530357 |
| NSG1 | neuron specific gene family member 1 | -0.00529628 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 | -0.0052856 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | -0.00527561 |
