| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | PH-797804 perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the PH-797804_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.129472 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.1057 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0935828 |
| NDRG1 | N-myc downstream regulated 1 | 0.0825378 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0621357 |
| PTMA | prothymosin, alpha | 0.0619876 |
| LDHA | lactate dehydrogenase A | 0.0616772 |
| SQSTM1 | sequestosome 1 | 0.0592557 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0568085 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.052698 |
| RPL37A | ribosomal protein L37a | 0.0515253 |
| RPS3 | ribosomal protein S3 | 0.050173 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0475934 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0453753 |
| NAV2 | neuron navigator 2 | 0.0433616 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0432044 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0428965 |
| B2M | beta-2-microglobulin | 0.0417232 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.040877 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0401373 |
| RPS12 | ribosomal protein S12 | 0.0399497 |
| PRELID2 | PRELI domain containing 2 | 0.0392061 |
| FLNB | filamin B, beta | 0.0390232 |
| OGA | O-GlcNAcase | 0.0389357 |
| TMSB10 | thymosin beta 10 | 0.0388484 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0386352 |
| CD44 | CD44 molecule (Indian blood group) | 0.0376031 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0372074 |
| RPS24 | ribosomal protein S24 | 0.0370179 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0364756 |
| RPL26 | ribosomal protein L26 | 0.0356502 |
| RPLP1 | ribosomal protein, large, P1 | 0.0352594 |
| LMNA | lamin A/C | 0.0351889 |
| CSTB | cystatin B (stefin B) | 0.0348142 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0345022 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.034449 |
| CAVIN1 | caveolae associated protein 1 | 0.0338196 |
| HDAC9 | histone deacetylase 9 | 0.0330349 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.032721 |
| RPLP2 | ribosomal protein, large, P2 | 0.0321278 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0321093 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0316293 |
| RPS8 | ribosomal protein S8 | 0.0315294 |
| FAM107B | family with sequence similarity 107, member B | 0.028819 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0287363 |
| ASPH | aspartate beta-hydroxylase | 0.0286581 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0281722 |
| RPL36 | ribosomal protein L36 | 0.0280706 |
| CALR | calreticulin | 0.0280053 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.0279247 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0270077 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0269457 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0264231 |
| VIM | vimentin | 0.0260599 |
| SEC61G | Sec61 gamma subunit | 0.0254773 |
| RPL31 | ribosomal protein L31 | 0.0254613 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0253873 |
| RPS27A | ribosomal protein S27a | 0.0253055 |
| RPL23 | ribosomal protein L23 | 0.0244669 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.023962 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0238869 |
| RACK1 | receptor for activated C kinase 1 | 0.0238026 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0231727 |
| RPL12 | ribosomal protein L12 | 0.0227491 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0225702 |
| RPL7A | ribosomal protein L7a | 0.0223843 |
| RPS17 | ribosomal protein S17 | 0.0221056 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0220994 |
| RPS19 | ribosomal protein S19 | 0.0220323 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0219114 |
| FMNL2 | formin-like 2 | 0.0216849 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0215444 |
| S100A6 | S100 calcium binding protein A6 | 0.021356 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.021341 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.021271 |
| RPS13 | ribosomal protein S13 | 0.0211877 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0211089 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0205786 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0205614 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0205255 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0203759 |
| HIP1 | huntingtin interacting protein 1 | 0.020339 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0203139 |
| ATXN1 | ataxin 1 | 0.0202761 |
| STC1 | stanniocalcin 1 | 0.0202649 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.019894 |
| DST | dystonin | 0.0198266 |
| ARFGEF3 | ARFGEF family member 3 | 0.0197597 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0197244 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0196555 |
| MYO9A | myosin IXA | 0.0196385 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0196338 |
| RAI1 | retinoic acid induced 1 | 0.0195982 |
| MYOF | myoferlin | 0.0194006 |
| RPL35A | ribosomal protein L35a | 0.0193745 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0192144 |
| RPL37 | ribosomal protein L37 | 0.0190046 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0189248 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0188249 |
| SMYD3 | SET and MYND domain containing 3 | 0.0187408 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.376233 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.124288 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.116589 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0989532 |
| FN1 | fibronectin 1 | -0.0961157 |
| SUCNR1 | succinate receptor 1 | -0.0822985 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0665786 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0654466 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0653024 |
| LOX | lysyl oxidase | -0.0648651 |
| COL5A1 | collagen, type V, alpha 1 | -0.0591096 |
| PLAT | plasminogen activator, tissue | -0.0573271 |
| COL5A2 | collagen, type V, alpha 2 | -0.0567848 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0564205 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0538246 |
| FOSL1 | FOS-like antigen 1 | -0.0509834 |
| CD99 | CD99 molecule | -0.0503432 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.047928 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0478128 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0477691 |
| COL1A2 | collagen, type I, alpha 2 | -0.0469298 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0442757 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0438735 |
| MAP1B | microtubule-associated protein 1B | -0.0430092 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0427076 |
| TPM1 | tropomyosin 1 (alpha) | -0.0415555 |
| WDR43 | WD repeat domain 43 | -0.0415305 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0415088 |
| CANX | calnexin | -0.0406021 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0391632 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0386947 |
| PRSS23 | protease, serine, 23 | -0.0383002 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0358637 |
| CUX1 | cut-like homeobox 1 | -0.035311 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0338005 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0314991 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0312007 |
| MX2 | MX dynamin-like GTPase 2 | -0.0296755 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0281536 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0276716 |
| KRT81 | keratin 81, type II | -0.0274489 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0273309 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0271265 |
| S100A10 | S100 calcium binding protein A10 | -0.0269701 |
| MEIS2 | Meis homeobox 2 | -0.0261617 |
| DCLK2 | doublecortin-like kinase 2 | -0.0254429 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0251503 |
| TNS3 | tensin 3 | -0.0248411 |
| POTEF | POTE ankyrin domain family, member F | -0.0243233 |
| BCL2L1 | BCL2-like 1 | -0.0238701 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0238004 |
| ACTG1 | actin gamma 1 | -0.023745 |
| SRPK2 | SRSF protein kinase 2 | -0.023737 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0234727 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -0.0234514 |
| RUNX1 | runt-related transcription factor 1 | -0.02341 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0230959 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0229584 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0216003 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0213635 |
| LAMB1 | laminin, beta 1 | -0.0211555 |
| ZMAT3 | zinc finger, matrin-type 3 | -0.0211268 |
| IL7R | interleukin 7 receptor | -0.020844 |
| FGF13 | fibroblast growth factor 13 | -0.0208042 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.0205028 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0203849 |
| JAZF1 | JAZF zinc finger 1 | -0.020236 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0200698 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0195618 |
| LRRC17 | leucine rich repeat containing 17 | -0.0190598 |
| ITPRIP | inositol 1,4,5-trisphosphate receptor interacting protein | -0.018774 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0187607 |
| RIGI | RNA sensor RIG-I | -0.0187514 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0184524 |
| COL1A1 | collagen, type I, alpha 1 | -0.0183786 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0182571 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0182402 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0182233 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0182217 |
| PCDH7 | protocadherin 7 | -0.0181104 |
| TAGLN2 | transgelin 2 | -0.0178696 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | -0.0176967 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0172551 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.016963 |
| RNF145 | ring finger protein 145 | -0.0169496 |
| VEGFC | vascular endothelial growth factor C | -0.0168399 |
| ATP13A3 | ATPase type 13A3 | -0.0166423 |
| RASAL2 | RAS protein activator like 2 | -0.0165365 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0163207 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.016319 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0162597 |
| MED13L | mediator complex subunit 13-like | -0.0160302 |
| INSIG1 | insulin induced gene 1 | -0.0159381 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0159365 |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 | -0.0158473 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0155992 |
| PLCB4 | phospholipase C, beta 4 | -0.0154206 |
| TENM3 | teneurin transmembrane protein 3 | -0.0153138 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.015201 |
| PODXL | podocalyxin-like | -0.0151835 |
