| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | PH-797804 perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the PH-797804_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.191346 |
| VCL | vinculin | 0.146299 |
| FMN1 | formin 1 | 0.145062 |
| LSAMP | limbic system-associated membrane protein | 0.118842 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0951286 |
| SYT1 | synaptotagmin I | 0.0834196 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0801202 |
| TLE4 | transducin-like enhancer of split 4 | 0.0796335 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0733073 |
| RPL23 | ribosomal protein L23 | 0.0731612 |
| VIM | vimentin | 0.0720648 |
| PTMA | prothymosin, alpha | 0.0664464 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0640005 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0577589 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0571497 |
| RPLP1 | ribosomal protein, large, P1 | 0.0560425 |
| VMP1 | vacuole membrane protein 1 | 0.0559935 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0556034 |
| RPS12 | ribosomal protein S12 | 0.0545251 |
| RPL19 | ribosomal protein L19 | 0.0541335 |
| RPL37A | ribosomal protein L37a | 0.0513309 |
| RPS3 | ribosomal protein S3 | 0.0510494 |
| PRKCA | protein kinase C, alpha | 0.0458946 |
| BPTF | bromodomain PHD finger transcription factor | 0.0457063 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0445429 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0430279 |
| MSI2 | musashi RNA-binding protein 2 | 0.0426317 |
| MEIS2 | Meis homeobox 2 | 0.0424399 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0418603 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0401839 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0391921 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0384623 |
| B2M | beta-2-microglobulin | 0.0373257 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0366065 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0361005 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0360656 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0360106 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0354155 |
| RPS24 | ribosomal protein S24 | 0.0353179 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0345852 |
| SMYD3 | SET and MYND domain containing 3 | 0.0336003 |
| TPM1 | tropomyosin 1 (alpha) | 0.0330637 |
| MAP1B | microtubule-associated protein 1B | 0.0325951 |
| TMSB10 | thymosin beta 10 | 0.032369 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.032215 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0318773 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0317299 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0315284 |
| SIK2 | salt-inducible kinase 2 | 0.031042 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.030644 |
| PLPP1 | phospholipid phosphatase 1 | 0.0302387 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.030173 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0298441 |
| TRIB2 | tribbles pseudokinase 2 | 0.0296128 |
| GLCCI1 | glucocorticoid induced 1 | 0.0296127 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0295688 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0295522 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0294776 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0294221 |
| DST | dystonin | 0.0293724 |
| FERMT2 | fermitin family member 2 | 0.0292261 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0291304 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0290801 |
| CRH | corticotropin releasing hormone | 0.0290172 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0289897 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0287243 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0286608 |
| ENAH | enabled homolog (Drosophila) | 0.028388 |
| PLAT | plasminogen activator, tissue | 0.0283516 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0280994 |
| RAD51B | RAD51 paralog B | 0.02801 |
| PGK1 | phosphoglycerate kinase 1 | 0.0269283 |
| ASPH | aspartate beta-hydroxylase | 0.0267193 |
| RPS6 | ribosomal protein S6 | 0.0265737 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0264424 |
| RPL26 | ribosomal protein L26 | 0.026149 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0260272 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0257543 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0256978 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0255529 |
| RPS17 | ribosomal protein S17 | 0.0255121 |
| FAM107B | family with sequence similarity 107, member B | 0.0255046 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0250466 |
| FTL | ferritin, light polypeptide | 0.0248546 |
| RPL36 | ribosomal protein L36 | 0.0247302 |
| RPL12 | ribosomal protein L12 | 0.0247251 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0245291 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0244236 |
| SIK3 | SIK family kinase 3 | 0.0242556 |
| RPS19 | ribosomal protein S19 | 0.0240654 |
| EGR1 | early growth response 1 | 0.0239828 |
| KLF6 | Kruppel-like factor 6 | 0.0236558 |
| TPM4 | tropomyosin 4 | 0.0236204 |
| INTS6 | integrator complex subunit 6 | 0.023503 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0233994 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0231293 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0230807 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0230582 |
| HOMER1 | homer scaffolding protein 1 | 0.0229655 |
| RNF213 | ring finger protein 213 | 0.0228588 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.100686 |
| WDR43 | WD repeat domain 43 | -0.0152007 |
| KIAA1217 | KIAA1217 | -0.0146419 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0132532 |
| SETD5 | SET domain containing 5 | -0.012725 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.0113656 |
| HMGA1 | high mobility group AT-hook 1 | -0.0107978 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.010773 |
| USPL1 | ubiquitin specific peptidase like 1 | -0.010483 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0102568 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0102026 |
| RPL11 | ribosomal protein L11 | -0.0101447 |
| GDF15 | growth differentiation factor 15 | -0.0101322 |
| WDR49 | WD repeat domain 49 | -0.0100491 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00993716 |
| ZNF292 | zinc finger protein 292 | -0.00965103 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00953882 |
| SART3 | squamous cell carcinoma antigen recognized by T cells 3 | -0.00950407 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | -0.00913973 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | -0.00907003 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0090379 |
| DIAPH3 | diaphanous-related formin 3 | -0.00897092 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.00871195 |
| CCNL1 | cyclin L1 | -0.00870508 |
| RFX7 | regulatory factor X, 7 | -0.00869475 |
| VGLL4 | vestigial-like family member 4 | -0.00869029 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00865046 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.00840393 |
| NCOA2 | nuclear receptor coactivator 2 | -0.00827547 |
| KIF13A | kinesin family member 13A | -0.00823407 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.00819695 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.00817112 |
| HMGB1 | high mobility group box 1 | -0.0081256 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | -0.00810476 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.00807629 |
| ATP13A3 | ATPase type 13A3 | -0.00806771 |
| MPHOSPH9 | M-phase phosphoprotein 9 | -0.00805086 |
| PPP4R3A | protein phosphatase 4 regulatory subunit 3A | -0.00802671 |
| OSBP | oxysterol binding protein | -0.00791251 |
| GSPT1 | G1 to S phase transition 1 | -0.00788942 |
| NOL11 | nucleolar protein 11 | -0.00781885 |
| TP53 | tumor protein p53 | -0.00780667 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.00779958 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.00771819 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.00769397 |
| BUB3 | BUB3 mitotic checkpoint protein | -0.00767547 |
| SF3B3 | splicing factor 3b, subunit 3, 130kDa | -0.00766275 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.00765164 |
| KIF1B | kinesin family member 1B | -0.00764008 |
| TCERG1 | transcription elongation regulator 1 | -0.00762787 |
| CGGBP1 | CGG triplet repeat binding protein 1 | -0.00754333 |
| RNF4 | ring finger protein 4 | -0.00752423 |
| SIN3A | SIN3 transcription regulator family member A | -0.00749244 |
| SIAH1 | siah E3 ubiquitin protein ligase 1 | -0.00742029 |
| SRPK2 | SRSF protein kinase 2 | -0.00741715 |
| RREB1 | ras responsive element binding protein 1 | -0.00735922 |
| GSK3B | glycogen synthase kinase 3 beta | -0.00734188 |
| HAUS6 | HAUS augmin-like complex, subunit 6 | -0.00732837 |
| ANXA2 | annexin A2 | -0.00729208 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.00728021 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.00727455 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0071888 |
| GID8 | GID complex subunit 8 | -0.00717123 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.00712461 |
| FUS | FUS RNA binding protein | -0.0070984 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.00709649 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00707581 |
| XPO1 | exportin 1 | -0.00706702 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.00704523 |
| OTUD4 | OTU deubiquitinase 4 | -0.00701918 |
| SHTN1 | shootin 1 | -0.00700596 |
| PPP6C | protein phosphatase 6, catalytic subunit | -0.00699558 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.00695203 |
| LAMA5 | laminin, alpha 5 | -0.00694033 |
| NDC1 | NDC1 transmembrane nucleoporin | -0.00691296 |
| PDCD10 | programmed cell death 10 | -0.00690413 |
| FOXK2 | forkhead box K2 | -0.00687711 |
| PRRC1 | proline-rich coiled-coil 1 | -0.00685198 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.00685124 |
| TRIP4 | thyroid hormone receptor interactor 4 | -0.00685014 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.00683693 |
| GEMIN5 | gem (nuclear organelle) associated protein 5 | -0.00683629 |
| EWSR1 | EWS RNA-binding protein 1 | -0.00681801 |
| MTMR12 | myotubularin related protein 12 | -0.0067834 |
| CCNT2 | cyclin T2 | -0.00673851 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.00671398 |
| KIFAP3 | kinesin-associated protein 3 | -0.00667163 |
| FASN | fatty acid synthase | -0.00666286 |
| MANBA | mannosidase, beta A, lysosomal | -0.00664838 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.00663779 |
| RIOK3 | RIO kinase 3 | -0.00662917 |
| FBXO45 | F-box protein 45 | -0.0065989 |
| CCDC59 | coiled-coil domain containing 59 | -0.00657919 |
| MIGA1 | mitoguardin 1 | -0.00655698 |
| TUBA1B | tubulin, alpha 1b | -0.00655041 |
| SP3 | Sp3 transcription factor | -0.00654729 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0065411 |
| IMPA1 | inositol(myo)-1(or 4)-monophosphatase 1 | -0.00653005 |
| CYLD | cylindromatosis (turban tumor syndrome) | -0.00650051 |
| PLXNB2 | plexin B2 | -0.00647826 |
