| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | PH-797804 perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the PH-797804_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.207895 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.120885 |
| LMO7 | LIM domain 7 | 0.111624 |
| FAT1 | FAT atypical cadherin 1 | 0.107308 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0926212 |
| RPS12 | ribosomal protein S12 | 0.0890044 |
| NDRG1 | N-myc downstream regulated 1 | 0.0682809 |
| EREG | epiregulin | 0.0669848 |
| CALR | calreticulin | 0.0549698 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.054899 |
| NEBL | nebulette | 0.0513097 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0508101 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0473753 |
| PRELID2 | PRELI domain containing 2 | 0.0471142 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0469854 |
| DSPP | dentin sialophosphoprotein | 0.0455591 |
| RPS3 | ribosomal protein S3 | 0.0451786 |
| ASPH | aspartate beta-hydroxylase | 0.0451781 |
| ATXN1 | ataxin 1 | 0.0451244 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0443199 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0440712 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0405218 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0400521 |
| RPL18 | ribosomal protein L18 | 0.0396702 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0372956 |
| H1-0 | H1.0 linker histone | 0.0371799 |
| FAM13A | family with sequence similarity 13, member A | 0.0367524 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0361767 |
| MED13 | mediator complex subunit 13 | 0.0358414 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0358294 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0354348 |
| RPS19 | ribosomal protein S19 | 0.0350066 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0349386 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0347242 |
| CADPS | Ca++-dependent secretion activator | 0.0346686 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0337263 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0331183 |
| LDHA | lactate dehydrogenase A | 0.0330991 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0329967 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0321155 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0317313 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.0314131 |
| RPS2 | ribosomal protein S2 | 0.0303048 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0300999 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.030039 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0292113 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0291481 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0290428 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.028978 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0285361 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.028478 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0284162 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0283316 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0282864 |
| RPL37A | ribosomal protein L37a | 0.0280646 |
| RPS18 | ribosomal protein S18 | 0.0278523 |
| PGK1 | phosphoglycerate kinase 1 | 0.0270536 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0267233 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0266637 |
| TMF1 | TATA element modulatory factor 1 | 0.0261045 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0260731 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.0260217 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0260016 |
| RPL36 | ribosomal protein L36 | 0.0258065 |
| SERINC5 | serine incorporator 5 | 0.0256082 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0254908 |
| MUC13 | mucin 13, cell surface associated | 0.025194 |
| OGA | O-GlcNAcase | 0.0246478 |
| SSR1 | signal sequence receptor, alpha | 0.0241325 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0239052 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.02385 |
| HDLBP | high density lipoprotein binding protein | 0.0236542 |
| RPL26 | ribosomal protein L26 | 0.0235869 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0235127 |
| FTL | ferritin, light polypeptide | 0.0234416 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.022952 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0228339 |
| TPD52 | tumor protein D52 | 0.0228303 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0226934 |
| COG5 | component of oligomeric golgi complex 5 | 0.0226347 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0226277 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.022227 |
| LIMA1 | LIM domain and actin binding 1 | 0.021964 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0216841 |
| RNF145 | ring finger protein 145 | 0.0216765 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0216058 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0214602 |
| GOLGA4 | golgin A4 | 0.0213698 |
| VEGFA | vascular endothelial growth factor A | 0.0213622 |
| RNF43 | ring finger protein 43 | 0.0212744 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0212642 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0212629 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0211726 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.0211427 |
| RPLP1 | ribosomal protein, large, P1 | 0.0208513 |
| RPS17 | ribosomal protein S17 | 0.0208299 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0208008 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0206246 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0203076 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0202192 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.207018 |
| PTMA | prothymosin, alpha | -0.14757 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.115933 |
| ACTG1 | actin gamma 1 | -0.0931356 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0920871 |
| TMSB10 | thymosin beta 10 | -0.0725728 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0704318 |
| VCL | vinculin | -0.0679921 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0675797 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0638195 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0630588 |
| GPHN | gephyrin | -0.0614594 |
| RPL35A | ribosomal protein L35a | -0.057035 |
| RPS6 | ribosomal protein S6 | -0.0517258 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.048776 |
| RPS23 | ribosomal protein S23 | -0.0445082 |
| RPL34 | ribosomal protein L34 | -0.0435296 |
| ANXA2 | annexin A2 | -0.0434227 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0425096 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0417828 |
| IER3 | immediate early response 3 | -0.0404789 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0391335 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.036107 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0350208 |
| TFF1 | trefoil factor 1 | -0.0348538 |
| EGR1 | early growth response 1 | -0.0343977 |
| RPL8 | ribosomal protein L8 | -0.0343496 |
| FOSL1 | FOS-like antigen 1 | -0.0335802 |
| WDR43 | WD repeat domain 43 | -0.0333093 |
| RPS29 | ribosomal protein S29 | -0.0330713 |
| PIGR | polymeric immunoglobulin receptor | -0.0329608 |
| LAMA4 | laminin, alpha 4 | -0.0321801 |
| HMGB1 | high mobility group box 1 | -0.0319234 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0316954 |
| RPS11 | ribosomal protein S11 | -0.0312193 |
| POTEF | POTE ankyrin domain family, member F | -0.0310277 |
| MUC17 | mucin 17, cell surface associated | -0.0306991 |
| CALB1 | calbindin 1, 28kDa | -0.0305852 |
| DEK | DEK proto-oncogene | -0.0304022 |
| CCND1 | cyclin D1 | -0.0288052 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0286307 |
| HMGA1 | high mobility group AT-hook 1 | -0.0283762 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0277397 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.027739 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0276073 |
| S100A6 | S100 calcium binding protein A6 | -0.0275851 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0271563 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0265317 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0263942 |
| ONECUT3 | one cut homeobox 3 | -0.0262756 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0252452 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0249964 |
| ACTN4 | actinin, alpha 4 | -0.0248999 |
| LSAMP | limbic system-associated membrane protein | -0.0248838 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0243255 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0241397 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.02412 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0237114 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0235926 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0229858 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0228756 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0228141 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0226001 |
| TPM4 | tropomyosin 4 | -0.0222661 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0219925 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0217136 |
| RPS15 | ribosomal protein S15 | -0.0216466 |
| S100A10 | S100 calcium binding protein A10 | -0.0214554 |
| RNF217 | ring finger protein 217 | -0.0212236 |
| FERMT1 | fermitin family member 1 | -0.0211411 |
| FUS | FUS RNA binding protein | -0.0209672 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0208057 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | -0.0205389 |
| ITGB4 | integrin, beta 4 | -0.0204506 |
| RPL38 | ribosomal protein L38 | -0.0204245 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0203871 |
| KLK10 | kallikrein-related peptidase 10 | -0.0203196 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0202433 |
| FLNB | filamin B, beta | -0.0198338 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0198311 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0196727 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0193818 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0183946 |
| FDPS | farnesyl diphosphate synthase | -0.0183314 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | -0.0182776 |
| PPP4R3A | protein phosphatase 4 regulatory subunit 3A | -0.0182195 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.0181894 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0181748 |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | -0.0181711 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | -0.0178683 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0175889 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0174924 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0173261 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0172943 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.017205 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0171342 |
| RLF | rearranged L-myc fusion | -0.0170197 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0162515 |
| GTPBP4 | GTP binding protein 4 | -0.0161605 |
| INSIG1 | insulin induced gene 1 | -0.0161565 |
