| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | PH-797804 perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the PH-797804_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.159249 |
| RPS12 | ribosomal protein S12 | 0.117729 |
| MT2A | metallothionein 2A | 0.104715 |
| RPS3 | ribosomal protein S3 | 0.0799575 |
| RPL37A | ribosomal protein L37a | 0.0746432 |
| VIM | vimentin | 0.0714766 |
| RPS8 | ribosomal protein S8 | 0.0575143 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0554361 |
| RPLP2 | ribosomal protein, large, P2 | 0.054629 |
| RPL23 | ribosomal protein L23 | 0.0539658 |
| RPS6 | ribosomal protein S6 | 0.0522439 |
| RPLP1 | ribosomal protein, large, P1 | 0.048836 |
| RPS24 | ribosomal protein S24 | 0.0470434 |
| RPS19 | ribosomal protein S19 | 0.0452509 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.042769 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0421828 |
| RPL36 | ribosomal protein L36 | 0.0406585 |
| TMSB10 | thymosin beta 10 | 0.0386268 |
| B2M | beta-2-microglobulin | 0.0380121 |
| RPL26 | ribosomal protein L26 | 0.0360064 |
| RPL31 | ribosomal protein L31 | 0.0352437 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0319064 |
| HDAC9 | histone deacetylase 9 | 0.0319058 |
| RPS13 | ribosomal protein S13 | 0.0317136 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0306648 |
| RPS25 | ribosomal protein S25 | 0.0303744 |
| RPL9 | ribosomal protein L9 | 0.0302823 |
| RPS17 | ribosomal protein S17 | 0.0300281 |
| RPL36A | ribosomal protein L36a | 0.0293957 |
| RPL5 | ribosomal protein L5 | 0.0293347 |
| RPS27A | ribosomal protein S27a | 0.0291268 |
| RPS4X | ribosomal protein S4, X-linked | 0.0278136 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0276348 |
| RPL37 | ribosomal protein L37 | 0.0272964 |
| RPL19 | ribosomal protein L19 | 0.0269621 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0268659 |
| NAV2 | neuron navigator 2 | 0.0260955 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.025558 |
| PRELID2 | PRELI domain containing 2 | 0.0250279 |
| RPL18 | ribosomal protein L18 | 0.0244821 |
| RPS18 | ribosomal protein S18 | 0.023687 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0236643 |
| RPL7A | ribosomal protein L7a | 0.0236583 |
| RPL12 | ribosomal protein L12 | 0.0229899 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0228747 |
| RPS14 | ribosomal protein S14 | 0.0226445 |
| RACK1 | receptor for activated C kinase 1 | 0.0224006 |
| RPL27A | ribosomal protein L27a | 0.0222422 |
| RPL7 | ribosomal protein L7 | 0.0221331 |
| VEGFA | vascular endothelial growth factor A | 0.0218629 |
| RAI1 | retinoic acid induced 1 | 0.0210121 |
| PCBP2 | poly(rC) binding protein 2 | 0.0205791 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0203875 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0203132 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0202808 |
| RPS27 | ribosomal protein S27 | 0.0201952 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0200313 |
| RPL27 | ribosomal protein L27 | 0.0197311 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0196519 |
| YBX1 | Y box binding protein 1 | 0.019616 |
| STC2 | stanniocalcin 2 | 0.0191244 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0181816 |
| FTL | ferritin, light polypeptide | 0.0180375 |
| RPL15 | ribosomal protein L15 | 0.0179488 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0177825 |
| RPS20 | ribosomal protein S20 | 0.0174733 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0174608 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0174601 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0173985 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0172133 |
| PTMA | prothymosin, alpha | 0.0171123 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0170731 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0170423 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0168594 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0167289 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0166864 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0165792 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0165271 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0164322 |
| RPS29 | ribosomal protein S29 | 0.0163846 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0163211 |
| RPL13A | ribosomal protein L13a | 0.0162996 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0161881 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0159982 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.015918 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0159015 |
| SMYD3 | SET and MYND domain containing 3 | 0.015842 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.015634 |
| SPAG9 | sperm associated antigen 9 | 0.0156239 |
| ATXN1 | ataxin 1 | 0.0155334 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.015525 |
| RPS10 | ribosomal protein S10 | 0.0155208 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0153446 |
| RPL28 | ribosomal protein L28 | 0.0151379 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.015089 |
| RPS2 | ribosomal protein S2 | 0.0150256 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0146449 |
| TRIM25 | tripartite motif containing 25 | 0.0145318 |
| RPS16 | ribosomal protein S16 | 0.0144782 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0143515 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.108458 |
| FN1 | fibronectin 1 | -0.0992596 |
| GLIS3 | GLIS family zinc finger 3 | -0.0985215 |
| FRMD4A | FERM domain containing 4A | -0.0970676 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0836983 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0799255 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.06363 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0602134 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0592345 |
| VCL | vinculin | -0.0542851 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0541313 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0515595 |
| COL1A1 | collagen, type I, alpha 1 | -0.0508795 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0492694 |
| VCAN | versican | -0.0455055 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0439321 |
| RAI14 | retinoic acid induced 14 | -0.0436621 |
| CD44 | CD44 molecule (Indian blood group) | -0.042883 |
| HMGA2 | high mobility group AT-hook 2 | -0.0407357 |
| CDH13 | cadherin 13 | -0.0401623 |
| INHBA | inhibin, beta A | -0.0394644 |
| ZNF292 | zinc finger protein 292 | -0.0390671 |
| COL1A2 | collagen, type I, alpha 2 | -0.0383893 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0375747 |
| IER3 | immediate early response 3 | -0.037502 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0368218 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0360145 |
| ACTG1 | actin gamma 1 | -0.0360061 |
| EGR1 | early growth response 1 | -0.0351833 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0351497 |
| DST | dystonin | -0.0335541 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0324835 |
| CTSB | cathepsin B | -0.0316287 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0308529 |
| THBS1 | thrombospondin 1 | -0.0303974 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0301686 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.028824 |
| PDE10A | phosphodiesterase 10A | -0.0288224 |
| LOX | lysyl oxidase | -0.0287765 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0277254 |
| RASAL2 | RAS protein activator like 2 | -0.0261636 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0255647 |
| TENM2 | teneurin transmembrane protein 2 | -0.0253715 |
| CLMP | CXADR-like membrane protein | -0.0253587 |
| NAV1 | neuron navigator 1 | -0.0253382 |
| TPM4 | tropomyosin 4 | -0.0253096 |
| KRT19 | keratin 19, type I | -0.0247619 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0245411 |
| ANXA2 | annexin A2 | -0.0245361 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0243702 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0239637 |
| TMEM132D | transmembrane protein 132D | -0.023435 |
| TMSB4X | thymosin beta 4, X-linked | -0.0232642 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0231045 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0230129 |
| NRN1 | neuritin 1 | -0.022025 |
| RND3 | Rho family GTPase 3 | -0.0218502 |
| TUBB | tubulin, beta class I | -0.0217114 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0215251 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0210904 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0210633 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0210118 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0208697 |
| FBXO32 | F-box protein 32 | -0.0207722 |
| BNC2 | basonuclin 2 | -0.0207406 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0204038 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0199096 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0197818 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.019742 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0197159 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0197023 |
| THBS2 | thrombospondin 2 | -0.0195341 |
| UBC | ubiquitin C | -0.0195151 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0194758 |
| NABP1 | nucleic acid binding protein 1 | -0.0194283 |
| DIAPH2 | diaphanous-related formin 2 | -0.0193948 |
| STC1 | stanniocalcin 1 | -0.0192815 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0191458 |
| AHNAK | AHNAK nucleoprotein | -0.0190989 |
| JUN | jun proto-oncogene | -0.0190398 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0187863 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0187108 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0186648 |
| BICC1 | BicC family RNA binding protein 1 | -0.0185386 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0184686 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0183848 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -0.017849 |
| ERBIN | erbb2 interacting protein | -0.0177757 |
| ATP13A3 | ATPase type 13A3 | -0.0176505 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0172968 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0172116 |
| WDR43 | WD repeat domain 43 | -0.0171867 |
| HLA-B | major histocompatibility complex, class I, B | -0.0167525 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0164433 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0164124 |
| FOSL1 | FOS-like antigen 1 | -0.0163174 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0161076 |
| PHF3 | PHD finger protein 3 | -0.0159549 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0158368 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0157297 |
