| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | PH-797804 perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the PH-797804_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.29227 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.232732 |
| EXT1 | exostosin glycosyltransferase 1 | 0.148713 |
| SQSTM1 | sequestosome 1 | 0.116709 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.106623 |
| ASPH | aspartate beta-hydroxylase | 0.104011 |
| TMEM156 | transmembrane protein 156 | 0.0828691 |
| SMAD3 | SMAD family member 3 | 0.0657097 |
| VCL | vinculin | 0.0652952 |
| EREG | epiregulin | 0.0641874 |
| CANX | calnexin | 0.0596588 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0541295 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0535115 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0514872 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0504589 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.049344 |
| NTN4 | netrin 4 | 0.0486307 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0480974 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0475179 |
| TXNRD1 | thioredoxin reductase 1 | 0.0463849 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0458312 |
| TPR | translocated promoter region, nuclear basket protein | 0.0455049 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0447636 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0431839 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0430049 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0413949 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0403033 |
| RAB10 | RAB10, member RAS oncogene family | 0.0397112 |
| GLIS3 | GLIS family zinc finger 3 | 0.0393916 |
| STC2 | stanniocalcin 2 | 0.0377949 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0377844 |
| SEPTIN9 | septin 9 | 0.0377418 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0374795 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0373201 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0372415 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0367401 |
| SSH1 | slingshot protein phosphatase 1 | 0.036402 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0361915 |
| SMYD3 | SET and MYND domain containing 3 | 0.0361543 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0360739 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0358256 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0342707 |
| LOXL2 | lysyl oxidase-like 2 | 0.0341747 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0341378 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0336485 |
| RASAL2 | RAS protein activator like 2 | 0.033627 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0335007 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0328559 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0327241 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0322972 |
| ITGA1 | integrin, alpha 1 | 0.0321937 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0313387 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0305959 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0305819 |
| HLA-B | major histocompatibility complex, class I, B | 0.0303517 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0302063 |
| APP | amyloid beta (A4) precursor protein | 0.0300431 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0299487 |
| SVIL | supervillin | 0.0296669 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0296633 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0296583 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.029516 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0293962 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0293644 |
| OSMR | oncostatin M receptor | 0.0288315 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0286129 |
| B2M | beta-2-microglobulin | 0.0284472 |
| RBM39 | RNA binding motif protein 39 | 0.02814 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0278062 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0277695 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0276104 |
| NXN | nucleoredoxin | 0.0272832 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0270475 |
| DST | dystonin | 0.0269771 |
| KLHL5 | kelch-like family member 5 | 0.0268351 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.026799 |
| RAB31 | RAB31, member RAS oncogene family | 0.0265929 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0265155 |
| IL6ST | interleukin 6 signal transducer | 0.025609 |
| SIK3 | SIK family kinase 3 | 0.0253872 |
| GPATCH2L | G patch domain containing 2-like | 0.0252704 |
| IER3 | immediate early response 3 | 0.0252487 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0249442 |
| ENO1 | enolase 1, (alpha) | 0.024781 |
| ENAH | enabled homolog (Drosophila) | 0.0246956 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0246504 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0244146 |
| ATF6 | activating transcription factor 6 | 0.0242758 |
| S100A10 | S100 calcium binding protein A10 | 0.0242598 |
| CLTC | clathrin, heavy chain (Hc) | 0.0242582 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0241786 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0241637 |
| SYT1 | synaptotagmin I | 0.0241134 |
| PALLD | palladin, cytoskeletal associated protein | 0.0238862 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.0237192 |
| OGA | O-GlcNAcase | 0.0236862 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.023685 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0235907 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0233381 |
| LMNA | lamin A/C | 0.023173 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.0836283 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0653756 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0543746 |
| TMEM165 | transmembrane protein 165 | -0.0407124 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0397943 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0335934 |
| VEGFA | vascular endothelial growth factor A | -0.0334469 |
| POTEF | POTE ankyrin domain family, member F | -0.033062 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.031634 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0301227 |
| PLIN2 | perilipin 2 | -0.0280693 |
| PTMA | prothymosin, alpha | -0.0280072 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0258288 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0230282 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0183818 |
| HMGA1 | high mobility group AT-hook 1 | -0.0179748 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0176272 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0171952 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0165089 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0155528 |
| HDGF | hepatoma-derived growth factor | -0.0133372 |
| PFN1 | profilin 1 | -0.013321 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0132633 |
| FLNB | filamin B, beta | -0.0130906 |
| FAM13A | family with sequence similarity 13, member A | -0.0124466 |
| LOX | lysyl oxidase | -0.0122127 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0122046 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0121416 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0121151 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.012015 |
| RPL21 | ribosomal protein L21 | -0.0119335 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0116457 |
| ATN1 | atrophin 1 | -0.0115307 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.011327 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.0111716 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0107131 |
| IGF2 | insulin-like growth factor 2 | -0.0105969 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0105328 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0104123 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00985594 |
| RIC1 | RAB6A GEF complex partner 1 | -0.00968585 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0094505 |
| HSPB1 | heat shock 27kDa protein 1 | -0.00931713 |
| TMSB10 | thymosin beta 10 | -0.00920747 |
| TOB2 | transducer of ERBB2, 2 | -0.00911173 |
| CTSD | cathepsin D | -0.00892623 |
| MNT | MAX network transcriptional repressor | -0.00891972 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.00870702 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.00858478 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.00846474 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | -0.00842568 |
| RNF145 | ring finger protein 145 | -0.00836995 |
| RNASEH2A | ribonuclease H2, subunit A | -0.00836079 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.00831271 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.00826446 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.00802182 |
| GOLGA4 | golgin A4 | -0.00797141 |
| ZFP36 | ZFP36 ring finger protein | -0.0079677 |
| HLA-G | major histocompatibility complex, class I, G | -0.00796673 |
| PGM3 | phosphoglucomutase 3 | -0.00792392 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.0079111 |
| AGRN | agrin | -0.00786554 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.00781937 |
| CADM1 | cell adhesion molecule 1 | -0.00773831 |
| SRP54 | signal recognition particle 54kDa | -0.00764901 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.00757962 |
| TFG | TRK-fused gene | -0.00746472 |
| MYO1B | myosin IB | -0.00740282 |
| COG5 | component of oligomeric golgi complex 5 | -0.00739915 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.00739696 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.00736594 |
| ACTG1 | actin gamma 1 | -0.00733028 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.00732847 |
| CFAP96 | cilia and flagella associated protein 96 | -0.00728414 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.00727525 |
| NBEAL1 | neurobeachin-like 1 | -0.00724809 |
| TBC1D20 | TBC1 domain family, member 20 | -0.00720082 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.00718789 |
| SSR4 | signal sequence receptor, delta | -0.00716681 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.00710699 |
| LRRC23 | leucine rich repeat containing 23 | -0.00710152 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00705395 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.00704458 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.00702649 |
| SLC43A3 | solute carrier family 43, member 3 | -0.00699875 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00698341 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.00697988 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.00697982 |
| ARF4 | ADP-ribosylation factor 4 | -0.00690036 |
| CFB | complement factor B | -0.00685228 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.00665247 |
| INSIG2 | insulin induced gene 2 | -0.0066379 |
| ASTN2 | astrotactin 2 | -0.00657688 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.00655455 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.00653133 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | -0.00647687 |
| MXD1 | MAX dimerization protein 1 | -0.00645397 |
| FOSL2 | FOS-like antigen 2 | -0.00644741 |
| TAPBP | TAP binding protein (tapasin) | -0.00643904 |
| NUCB2 | nucleobindin 2 | -0.00642536 |
