| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the PHA-00767505E-6591 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTB | actin, beta |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| ASTN2 | astrotactin 2 |
| ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A |
| BBS9 | Bardet-Biedl syndrome 9 |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C6ORF62 | chromosome 6 open reading frame 62 |
| CCNG2 | cyclin G2 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| COL6A2 | collagen, type VI, alpha 2 |
| CREB1 | cAMP responsive element binding protein 1 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| CTNS | cystinosin, lysosomal cystine transporter |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DIAPH1 | diaphanous-related formin 1 |
| EIF5A | eukaryotic translation initiation factor 5A |
| ENO1 | enolase 1, (alpha) |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 |
| EPS8L1 | EPS8-like 1 |
| ETV1 | ets variant 1 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FBLN1 | fibulin 1 |
| FH | fumarate hydratase |
| FHL1 | four and a half LIM domains 1 |
| FNTB | farnesyltransferase, CAAX box, beta |
| FUS | FUS RNA binding protein |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase |
| GATAD1 | GATA zinc finger domain containing 1 |
| GLUL | glutamate-ammonia ligase |
| GMIP | GEM interacting protein |
| GNS | glucosamine (N-acetyl)-6-sulfatase |
| H2AFX | H2A histone family, member X |
| HIGD2A | HIG1 hypoxia inducible domain family, member 2A |
| HIST1H2AJ | histone cluster 1, H2aj |
| HLA-G | major histocompatibility complex, class I, G |
| HOOK1 | hook microtubule-tethering protein 1 |
| IL17RC | interleukin 17 receptor C |
| ITGA10 | integrin, alpha 10 |
| LIMK2 | LIM domain kinase 2 |
| MBTPS1 | membrane-bound transcription factor peptidase, site 1 |
| METTL7A | methyltransferase like 7A |
| MPPE1 | metallophosphoesterase 1 |
| MTRR | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase |
| NEK2 | NIMA-related kinase 2 |
| NFRKB | nuclear factor related to kappaB binding protein |
| NFYC | nuclear transcription factor Y, gamma |
| NMT1 | N-myristoyltransferase 1 |
| NOTCH2 | notch 2 |
| OCRL | oculocerebrorenal syndrome of Lowe |
| PLAU | plasminogen activator, urokinase |
| PLEC | plectin |
| POGK | pogo transposable element with KRAB domain |
| POLR3C | polymerase (RNA) III (DNA directed) polypeptide C (62kD) |
| PPIF | peptidylprolyl isomerase F |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PRNP | prion protein |
| PRPF31 | pre-mRNA processing factor 31 |
| PRPF4 | pre-mRNA processing factor 4 |
| PRUNE | prune exopolyphosphatase |
| PSAT1 | phosphoserine aminotransferase 1 |
| PSEN1 | presenilin 1 |
| PTBP1 | polypyrimidine tract binding protein 1 |
| PTK2 | protein tyrosine kinase 2 |
| R3HDM4 | R3H domain containing 4 |
| RAB11B | RAB11B, member RAS oncogene family |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) |
| RALB | v-ral simian leukemia viral oncogene homolog B |
| RBBP4 | retinoblastoma binding protein 4 |
| RDX | radixin |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF24 | ring finger protein 24 |
| RNFT1 | ring finger protein, transmembrane 1 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC43A3 | solute carrier family 43, member 3 |
| SMAD3 | SMAD family member 3 |
| SMG9 | SMG9 nonsense mediated mRNA decay factor |
| SPAG9 | sperm associated antigen 9 |
| SQLE | squalene epoxidase |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| STIP1 | stress-induced phosphoprotein 1 |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TFCP2 | transcription factor CP2 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TPD52L1 | tumor protein D52-like 1 |
| TRADD | TNFRSF1A-associated via death domain |
| TRIM29 | tripartite motif containing 29 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 |
| UNC119 | unc-119 homolog (C. elegans) |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| USB1 | U6 snRNA biogenesis 1 |
| WHSC1 | Wolf-Hirschhorn syndrome candidate 1 |
| WNK1 | WNK lysine deficient protein kinase 1 |
| ZNF324 | zinc finger protein 324 |
| ZNF45 | zinc finger protein 45 |
| Symbol | Name |
|---|---|
| ABHD8 | abhydrolase domain containing 8 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 |
| BANP | BTG3 associated nuclear protein |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BMP4 | bone morphogenetic protein 4 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| BTBD18 | BTB (POZ) domain containing 18 |
| BTC | betacellulin |
| C17ORF62 | chromosome 17 open reading frame 62 |
| C1S | complement component 1, s subcomponent |
| C22ORF29 | chromosome 22 open reading frame 29 |
| CCNJL | cyclin J-like |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CEL | carboxyl ester lipase |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| COBL | cordon-bleu WH2 repeat protein |
| COL21A1 | collagen, type XXI, alpha 1 |
| CPB2 | carboxypeptidase B2 (plasma) |
| CREB5 | cAMP responsive element binding protein 5 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CTSK | cathepsin K |
| CXORF56 | chromosome X open reading frame 56 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EFCAB2 | EF-hand calcium binding domain 2 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ERC2-IT1 | ERC2 intronic transcript 1 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| FLT4 | fms-related tyrosine kinase 4 |
| GAS8 | growth arrest-specific 8 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GIPR | gastric inhibitory polypeptide receptor |
| GSN-AS1 | GSN antisense RNA 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIRA | histone cell cycle regulator |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H4C | histone cluster 1, H4c |
| HIST1H4D | histone cluster 1, H4d |
| HOXC5 | homeobox C5 |
| HOXC8 | homeobox C8 |
| INCENP | inner centromere protein antigens 135/155kDa |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLHDC4 | kelch domain containing 4 |
| KRT4 | keratin 4, type II |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LIFR | leukemia inhibitory factor receptor alpha |
| LMNB1 | lamin B1 |
| LMTK1 | lemur tail kinase 1 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| MEOX1 | mesenchyme homeobox 1 |
| MT1M | metallothionein 1M |
| MX1 | MX dynamin-like GTPase 1 |
| NEK11 | NIMA-related kinase 11 |
| NRTN | neurturin |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PAQR5 | progestin and adipoQ receptor family member V |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PELP1 | proline, glutamate and leucine rich protein 1 |
| PHF14 | PHD finger protein 14 |
| PRAMEF11 | PRAME family member 11 |
| PRPH | peripherin |
| PRR7 | proline rich 7 (synaptic) |
| PTPRH | protein tyrosine phosphatase, receptor type, H |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SCNN1B | sodium channel, non voltage gated 1 beta subunit |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SLN | sarcolipin |
| SNHG3 | small nucleolar RNA host gene 3 |
| SPATA2L | spermatogenesis associated 2-like |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| TMEM183A | transmembrane protein 183A |
| TRABD | TraB domain containing |
| TRIM25 | tripartite motif containing 25 |
| TRNAU1AP | tRNA selenocysteine 1 associated protein 1 |
| TSC22D4 | TSC22 domain family, member 4 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| VPS37C | vacuolar protein sorting 37 homolog C (S. cerevisiae) |
| WDR25 | WD repeat domain 25 |
| XAB2 | XPA binding protein 2 |
| ZCCHC2 | zinc finger, CCHC domain containing 2 |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF446 | zinc finger protein 446 |