| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the PHA-00851261E-4333 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AADAC | arylacetamide deacetylase |
| ACTN2 | actinin, alpha 2 |
| ACVR1B | activin A receptor, type IB |
| ADAM28 | ADAM metallopeptidase domain 28 |
| ADD2 | adducin 2 (beta) |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ANGPT1 | angiopoietin 1 |
| ANKRD12 | ankyrin repeat domain 12 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ASPH | aspartate beta-hydroxylase |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| ATXN7L3B | ataxin 7-like 3B |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| C1ORF95 | chromosome 1 open reading frame 95 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit |
| CD52 | CD52 molecule |
| CLEC4E | C-type lectin domain family 4, member E |
| CLTCL1 | clathrin, heavy chain-like 1 |
| CNGA1 | cyclic nucleotide gated channel alpha 1 |
| CNTNAP2 | contactin associated protein-like 2 |
| CXXC4 | CXXC finger protein 4 |
| DLX2 | distal-less homeobox 2 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DOC2B | double C2-like domains, beta |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ESR1 | estrogen receptor 1 |
| EZR | ezrin |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FOXN2 | forkhead box N2 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GGT1 | gamma-glutamyltransferase 1 |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GPM6B | glycoprotein M6B |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H3E | histone cluster 1, H3e |
| HIST1H4C | histone cluster 1, H4c |
| HIST1H4F | histone cluster 1, H4f |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HPX | hemopexin |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IL1RN | interleukin 1 receptor antagonist |
| INO80D | INO80 complex subunit D |
| KAT6A | K(lysine) acetyltransferase 6A |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KIAA0100 | KIAA0100 |
| KIRREL | kin of IRRE like (Drosophila) |
| LMNB1 | lamin B1 |
| LOC157562 | uncharacterized LOC157562 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MED1 | mediator complex subunit 1 |
| MED18 | mediator complex subunit 18 |
| MED25 | mediator complex subunit 25 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NOP14-AS1 | NOP14 antisense RNA 1 |
| NOVA2 | neuro-oncological ventral antigen 2 |
| NPTX1 | neuronal pentraxin I |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OLFML2B | olfactomedin-like 2B |
| ONECUT2 | one cut homeobox 2 |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PHF3 | PHD finger protein 3 |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| RAB36 | RAB36, member RAS oncogene family |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) |
| REST | RE1-silencing transcription factor |
| RET | ret proto-oncogene |
| RNF122 | ring finger protein 122 |
| RNF43 | ring finger protein 43 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
| SF1 | splicing factor 1 |
| SLC17A2 | solute carrier family 17, member 2 |
| SMC1A | structural maintenance of chromosomes 1A |
| SP110 | SP110 nuclear body protein |
| SRPK3 | SRSF protein kinase 3 |
| STAT4 | signal transducer and activator of transcription 4 |
| TBXA2R | thromboxane A2 receptor |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| THRA | thyroid hormone receptor, alpha |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| UGCG | UDP-glucose ceramide glucosyltransferase |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C |
| WIZ | widely interspaced zinc finger motifs |
| ZMYM2 | zinc finger, MYM-type 2 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| AFF4 | AF4/FMR2 family, member 4 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| AXIN1 | axin 1 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| CAPN15 | calpain 15 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CBX4 | chromobox homolog 4 |
| CCDC106 | coiled-coil domain containing 106 |
| CCDC88C | coiled-coil domain containing 88C |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD53 | CD53 molecule |
| CES3 | carboxylesterase 3 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CISH | cytokine inducible SH2-containing protein |
| DBF4B | DBF4 zinc finger B |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| EFNB1 | ephrin-B1 |
| EN1 | engrailed homeobox 1 |
| ERCC2 | excision repair cross-complementation group 2 |
| EXOC5 | exocyst complex component 5 |
| FZD10 | frizzled class receptor 10 |
| GBX2 | gastrulation brain homeobox 2 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GTF2I | general transcription factor IIi |
| HOXC10 | homeobox C10 |
| HOXC11 | homeobox C11 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IFNA17 | interferon, alpha 17 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IL22 | interleukin 22 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KLC2 | kinesin light chain 2 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LRRC61 | leucine rich repeat containing 61 |
| MAP3K3 | mitogen-activated protein kinase kinase kinase 3 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MATN3 | matrilin 3 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MYO1D | myosin ID |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| OSBP2 | oxysterol binding protein 2 |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PDE8B | phosphodiesterase 8B |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha |
| PRSS53 | protease, serine, 53 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF146 | ring finger protein 146 |
| RUSC2 | RUN and SH3 domain containing 2 |
| S1PR1 | sphingosine-1-phosphate receptor 1 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SETBP1 | SET binding protein 1 |
| SETD1A | SET domain containing 1A |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SSBP3 | single stranded DNA binding protein 3 |
| STRA6 | stimulated by retinoic acid 6 |
| STRN4 | striatin, calmodulin binding protein 4 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SYCP2 | synaptonemal complex protein 2 |
| SYTL2 | synaptotagmin-like 2 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMEM8A | transmembrane protein 8A |
| TMEM8B | transmembrane protein 8B |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| TRABD | TraB domain containing |
| TSC22D4 | TSC22 domain family, member 4 |
| TTC30A | tetratricopeptide repeat domain 30A |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 |
| USP6 | ubiquitin specific peptidase 6 |
| UTRN | utrophin |
| VEGFB | vascular endothelial growth factor B |
| WDR25 | WD repeat domain 25 |
| ZNF10 | zinc finger protein 10 |
| ZNF155 | zinc finger protein 155 |
| ZNF711 | zinc finger protein 711 |
| ZNF76 | zinc finger protein 76 |