PHAX Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description phosphorylated adaptor for RNA export| (NCBI Entrez Gene Database, 51808)
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Genes

362 genes differentially expressed following the PHAX gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
TXNDC8 thioredoxin domain containing 8 (spermatozoa) 3.26234
OLIG2 oligodendrocyte lineage transcription factor 2 3.26234
SULT1A3 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 3.26234
C19ORF67 chromosome 19 open reading frame 67 3.26234
PECAM1 platelet/endothelial cell adhesion molecule 1 3.26234
ARSF arylsulfatase F 3.26234
ANKRD34A ankyrin repeat domain 34A 3.26234
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3 3.26234
FAM221B family with sequence similarity 221, member B 3.26234
NOTUM notum pectinacetylesterase homolog (Drosophila) 3.26234
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 3.26234
OR1L6 olfactory receptor, family 1, subfamily L, member 6 3.26234
COL16A1 collagen, type XVI, alpha 1 3.26234
EPHX4 epoxide hydrolase 4 3.26234
ZEB2 zinc finger E-box binding homeobox 2 3.26234
DNASE1L2 deoxyribonuclease I-like 2 3.26234
DCAF4L1 DDB1 and CUL4 associated factor 4-like 1 3.26234
HGD homogentisate 1,2-dioxygenase 3.26234
CAPNS2 calpain, small subunit 2 3.26234
HES3 hes family bHLH transcription factor 3 3.26234
AFM afamin 3.26234
SKOR1 SKI family transcriptional corepressor 1 3.26234
SKOR2 SKI family transcriptional corepressor 2 3.26234
LRRC56 leucine rich repeat containing 56 3.26234
PAX2 paired box 2 3.26234
LCN15 lipocalin 15 3.26234
ARRDC2 arrestin domain containing 2 3.26234
KHDC3L KH domain containing 3-like, subcortical maternal complex member 3.26234
SPAG8 sperm associated antigen 8 3.26234
NR4A3 nuclear receptor subfamily 4, group A, member 3 3.26234
MIXL1 Mix paired-like homeobox 3.26234
PRSS22 protease, serine, 22 3.26234
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 3.26234
AMPD1 adenosine monophosphate deaminase 1 3.26234
NPC1L1 NPC1-like 1 3.26234
MYOZ2 myozenin 2 3.26234
STOML3 stomatin (EPB72)-like 3 3.26234
IFITM10 interferon induced transmembrane protein 10 3.26234
ZPLD1 zona pellucida-like domain containing 1 3.26234
TDO2 tryptophan 2,3-dioxygenase 3.26234
SLC22A9 solute carrier family 22 (organic anion transporter), member 9 3.26234
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 3.26234
LRRIQ4 leucine-rich repeats and IQ motif containing 4 3.26234
S100A1 S100 calcium binding protein A1 3.26234
NPIPA7 nuclear pore complex interacting protein family, member A7 3.26234
MUC20 mucin 20, cell surface associated 3.26234
CRYGN crystallin, gamma N 3.26234
ADH6 alcohol dehydrogenase 6 (class V) 3.26234
ASGR2 asialoglycoprotein receptor 2 3.26234
CRYAA crystallin, alpha A 3.26234
SPON2 spondin 2, extracellular matrix protein 3.26234
EVPL envoplakin 3.26234
GREM1 gremlin 1, DAN family BMP antagonist 3.26234
LY6S lymphocyte antigen 6 family member S 3.26234
SIM1 single-minded family bHLH transcription factor 1 3.26234
NEURL3 neuralized E3 ubiquitin protein ligase 3 3.26234
SRPK3 SRSF protein kinase 3 3.26234
VSIG1 V-set and immunoglobulin domain containing 1 3.26234
HTR3C 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic 3.26234
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 3.26234
UBE2QL1 ubiquitin-conjugating enzyme E2Q family-like 1 3.26234
CFAP52 cilia and flagella associated protein 52 3.26234
HAL histidine ammonia-lyase 3.26234
PLEK2 pleckstrin 2 3.26234
STARD6 StAR-related lipid transfer (START) domain containing 6 3.26234
VN1R1 vomeronasal 1 receptor 1 3.26234
CLDN16 claudin 16 3.26234
SPEGNB SPEG neighbor 3.26234
CSP2 CS pseudogene 2 3.26234
DEFB109B defensin beta 109B 3.26234
TMT1B thiol methyltransferase 1B 3.26234
C20ORF204 chromosome 20 open reading frame 204 3.26234
H3-7 H3.7 histone (putative) 3.26234
TENT5D terminal nucleotidyltransferase 5D 3.26234
HYCC2 hyccin PI4KA lipid kinase complex subunit 2 3.26234
TBXT T-box transcription factor T 3.26234
OTOA otoancorin 3.26234
ZAR1 zygote arrest 1 3.26234
ABHD15 abhydrolase domain containing 15 3.26234
MPPED1 metallophosphoesterase domain containing 1 3.26234
MTMR11 myotubularin related protein 11 3.26234
HLX H2.0-like homeobox 3.26234
HRH1 histamine receptor H1 3.26234
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18 3.26234
CFAP74 cilia and flagella associated protein 74 3.26234
CD93 CD93 molecule 3.26234
NAPSA napsin A aspartic peptidase 3.26234
DNAJC5G DnaJ (Hsp40) homolog, subfamily C, member 5 gamma 3.26234
DNAJC5B DnaJ (Hsp40) homolog, subfamily C, member 5 beta 3.26234
MAP3K7CL MAP3K7 C-terminal like 3.26234
ALG1L2 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like 2 3.26234
LIPH lipase, member H 3.26234
TMPRSS11F transmembrane protease, serine 11F 3.26234
FPR2 formyl peptide receptor 2 3.26234
MYOT myotilin 3.26234
HSPB6 heat shock protein, alpha-crystallin-related, B6 3.26234
AWAT1 acyl-CoA wax alcohol acyltransferase 1 3.26234
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 3.26234
TSGA10IP testis specific, 10 interacting protein 3.26234
ZBTB16 zinc finger and BTB domain containing 16 3.26234
PCDHB12 protocadherin beta 12 3.26234
ARL5C ADP-ribosylation factor-like 5C 3.26234
DMP1 dentin matrix acidic phosphoprotein 1 3.26234
GGT5 gamma-glutamyltransferase 5 3.26234
DPF3 D4, zinc and double PHD fingers, family 3 3.26234
SPINK1 serine peptidase inhibitor, Kazal type 1 3.26234
XCR1 chemokine (C motif) receptor 1 3.26234
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) 3.26234
NOX3 NADPH oxidase 3 3.26234
NOX1 NADPH oxidase 1 3.26234
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 3.26234
TRADD TNFRSF1A-associated via death domain 3.26234
MEIS1 Meis homeobox 1 3.26234
PCDHAC2 protocadherin alpha subfamily C, 2 3.26234
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 3.26234
WDR17 WD repeat domain 17 3.26234
CASQ2 calsequestrin 2 (cardiac muscle) 3.26234
GLOD5 glyoxalase domain containing 5 3.26234
CTAGE9 CTAGE family, member 9 3.26234
ZNF541 zinc finger protein 541 3.26234
CNGB1 cyclic nucleotide gated channel beta 1 3.26234
CDC20B cell division cycle 20B 3.26234
HHATL hedgehog acyltransferase-like 3.26234
CLRN1 clarin 1 3.26234
CXCR6 chemokine (C-X-C motif) receptor 6 3.26234
GBX2 gastrulation brain homeobox 2 3.26234
TF transferrin 3.26234
EMP1 epithelial membrane protein 1 3.26234
SLC25A34 solute carrier family 25, member 34 3.26234
TBX1 T-box 1 3.26234
BCL2L15 BCL2-like 15 3.26234
TG thyroglobulin 3.26234
CISH cytokine inducible SH2-containing protein 3.26234
PDCD1LG2 programmed cell death 1 ligand 2 3.26234
CTSW cathepsin W 3.26234
PRSS33 protease, serine, 33 3.26234
PKHD1L1 polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1 3.26234
CFAP47 cilia and flagella associated protein 47 3.26234
KLK4 kallikrein-related peptidase 4 3.26234
ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B 3.26234
LGALS14 lectin, galactoside-binding, soluble, 14 3.26234
WNT7B wingless-type MMTV integration site family, member 7B 3.26234
CSF1R colony stimulating factor 1 receptor 3.26234
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 3.26234
DPH1 diphthamide biosynthesis 1 3.26234
CNR1 cannabinoid receptor 1 (brain) 3.26234
CD27 CD27 molecule 3.26234
SLC22A24 solute carrier family 22, member 24 3.26234
TP63 tumor protein p63 3.26234
PTPN7 protein tyrosine phosphatase, non-receptor type 7 3.26234
CFP complement factor properdin 3.26234
LY6G6C lymphocyte antigen 6 complex, locus G6C 3.26234
ARMCX6 armadillo repeat containing, X-linked 6 3.26234
FITM1 fat storage-inducing transmembrane protein 1 3.26234
CARNS1 carnosine synthase 1 3.26234
AMER3 APC membrane recruitment protein 3 3.26234
AMER2 APC membrane recruitment protein 2 3.26234
GOLGA8Q golgin A8 family, member Q 3.26234
CFI complement factor I 3.26234
ZNF534 zinc finger protein 534 3.26234
SYTL4 synaptotagmin-like 4 3.26234
SLC36A3 solute carrier family 36, member 3 3.26234
ACOX2 acyl-CoA oxidase 2, branched chain 3.26234
ZBED6 zinc finger, BED-type containing 6 3.26234
ART1 ADP-ribosyltransferase 1 3.26234
TRPM1 transient receptor potential cation channel, subfamily M, member 1 3.26234
RHAG Rh-associated glycoprotein 3.26234
FGF18 fibroblast growth factor 18 3.26234
NUTM2A NUT family member 2A 3.26234
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 3.26234
MRLN myoregulin 3.26234
BRDT bromodomain, testis-specific 3.26234
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 3.26234
ZNF831 zinc finger protein 831 3.26234
RPA4 replication protein A4, 30kDa 3.26234
PCDHGB7 protocadherin gamma subfamily B, 7 3.26234
EDN2 endothelin 2 3.26234
FCN3 ficolin (collagen/fibrinogen domain containing) 3 3.26234
PRRX1 paired related homeobox 1 3.26234
OR13A1 olfactory receptor, family 13, subfamily A, member 1 3.26234
ALOX15B arachidonate 15-lipoxygenase, type B 3.26234
CUX1 cut-like homeobox 1 3.23661
CCKBR cholecystokinin B receptor 3.23288
VIL1 villin 1 3.23288
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 3.17168
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1 3.119
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 3.01401
ART3 ADP-ribosyltransferase 3 2.99046
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.95538
SOCS2 suppressor of cytokine signaling 2 2.88525
ESYT2 extended synaptotagmin-like protein 2 2.86545
CACNG6 calcium channel, voltage-dependent, gamma subunit 6 2.78642
MT2A metallothionein 2A 2.66313
FAM184B family with sequence similarity 184, member B 2.65751
STEEP1 STING1 ER exit protein 1 2.59151
C16ORF95 chromosome 16 open reading frame 95 2.57433
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 2.57433
HHIPL1 HHIP-like 1 2.57433
MRPS6 mitochondrial ribosomal protein S6 2.55031
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 2.53174
PNPLA6 patatin-like phospholipase domain containing 6 2.50852
SARNP SAP domain containing ribonucleoprotein 2.50477
TDP2 tyrosyl-DNA phosphodiesterase 2 2.50068
VMA12 vacuolar ATPase assembly factor VMA12 2.49674
CNTFR ciliary neurotrophic factor receptor 2.49303
TMED6 transmembrane emp24 protein transport domain containing 6 2.49303
CSRNP3 cysteine-serine-rich nuclear protein 3 2.49303
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 2.49303
GRHL3 grainyhead-like 3 (Drosophila) 2.49303
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 2.4751
PNMA3 paraneoplastic Ma antigen 3 2.44363
LEF1 lymphoid enhancer-binding factor 1 2.43033
TTC36 tetratricopeptide repeat domain 36 2.43033
TSPAN19 tetraspanin 19 2.42298
TLE6 transducin-like enhancer of split 6 2.42298
MYT1L myelin transcription factor 1-like 2.42298
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2 2.38751
PNPLA2 patatin-like phospholipase domain containing 2 2.36692
CENPK centromere protein K 2.33992
POLE polymerase (DNA directed), epsilon, catalytic subunit 2.33725
CPVL carboxypeptidase, vitellogenic-like 2.3102
SKIC8 SKI8 subunit of superkiller complex 2.3102
NCAM2 neural cell adhesion molecule 2 2.30053
GLE1 GLE1 RNA export mediator 2.29805
DENND4B DENN/MADD domain containing 4B 2.2505
DOCK2 dedicator of cytokinesis 2 2.24712
TSACC TSSK6 activating co-chaperone 2.24663
UBAC1 UBA domain containing 1 2.2325
ARMC9 armadillo repeat containing 9 2.21954
SIMC1 SUMO-interacting motifs containing 1 2.20381
SHFL shiftless antiviral inhibitor of ribosomal frameshifting 2.20321
ARMCX4 armadillo repeat containing, X-linked 4 2.1974
SYNE4 spectrin repeat containing, nuclear envelope family member 4 2.17918
ASPHD2 aspartate beta-hydroxylase domain containing 2 2.16894
PTRH1 peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae) 2.15128
B3GAT2 beta-1,3-glucuronyltransferase 2 2.15112
ZNF85 zinc finger protein 85 2.12869
NAV1 neuron navigator 1 2.12782
NLRC5 NLR family, CARD domain containing 5 2.08008
CC2D2B coiled-coil and C2 domain containing 2B 2.08008
GPR34 G protein-coupled receptor 34 2.08008
CRHR2 corticotropin releasing hormone receptor 2 2.08008
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 2.08008
CENPV centromere protein V 2.07905
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2 2.07191
SAMHD1 SAM domain and HD domain 1 2.06132
RPL10 ribosomal protein L10 2.05673
PPARD peroxisome proliferator-activated receptor delta 2.04401
SF3B4 splicing factor 3b, subunit 4, 49kDa 2.02575
RMP24 ribonuclease MRP subunit p24 2.00666

decreased expression

Symbol Name Standardized Value
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 -3.26234
WDR31 WD repeat domain 31 -3.26234
LGALS7B lectin, galactoside-binding, soluble, 7B -3.26234
OR52A1 olfactory receptor, family 52, subfamily A, member 1 -3.26234
KRTAP13-4 keratin associated protein 13-4 -3.26234
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 -3.26234
OR2AG2 olfactory receptor, family 2, subfamily AG, member 2 -3.26234
GPR171 G protein-coupled receptor 171 -3.26234
ZC2HC1A zinc finger, C2HC-type containing 1A -3.26234
SFTPD surfactant protein D -3.26234
TBX6 T-box 6 -3.26234
F13A1 coagulation factor XIII, A1 polypeptide -3.26234
ZNF823 zinc finger protein 823 -3.26234
C3 complement component 3 -3.26234
SCIN scinderin -3.26234
PROM2 prominin 2 -3.26234
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein -3.26234
REN renin -3.26234
FGF20 fibroblast growth factor 20 -3.26234
SPNS2 spinster homolog 2 (Drosophila) -3.26234
YY2 YY2 transcription factor -3.26234
SPINK13 serine peptidase inhibitor, Kazal type 13 (putative) -3.26234
TMPRSS11E transmembrane protease, serine 11E -3.26234
FAM216B family with sequence similarity 216, member B -3.26234
EPCIP exosomal polycystin 1 interacting protein -3.26234
OVCH2 ovochymase 2 (gene/pseudogene) -3.26234
NIPSNAP3B nipsnap homolog 3B (C. elegans) -3.26234
NMUR1 neuromedin U receptor 1 -3.26234
NPB neuropeptide B -3.26234
CNGA4 cyclic nucleotide gated channel alpha 4 -3.26234
IMPG1 interphotoreceptor matrix proteoglycan 1 -3.26234
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 -3.26234
NYX nyctalopin -3.26234
DENND1C DENN/MADD domain containing 1C -3.26234
LOXHD1 lipoxygenase homology domains 1 -3.26234
SLC38A5 solute carrier family 38, member 5 -3.26234
AMIGO1 adhesion molecule with Ig-like domain 1 -3.26234
CFAP73 cilia and flagella associated protein 73 -3.26234
CFAP61 cilia and flagella associated protein 61 -3.26234
CFAP54 cilia and flagella associated 54 -3.26234
CXCR2 chemokine (C-X-C motif) receptor 2 -3.26234
OR52P1 olfactory receptor family 52 subfamily P member 1 (gene/pseudogene) -3.26234
ADAM8 ADAM metallopeptidase domain 8 -3.26234
PCSK4 proprotein convertase subtilisin/kexin type 4 -3.26234
C2ORF72 chromosome 2 open reading frame 72 -3.26234
SMIM47 small integral membrane protein 47 -3.26234
BTNL8 butyrophilin-like 8 -3.26234
CPHXL2 cytoplasmic polyadenylated homeobox like 2 -3.26234
ARSL arylsulfatase L -3.26234
FRS3 fibroblast growth factor receptor substrate 3 -3.26234
NTMT2 N-terminal Xaa-Pro-Lys N-methyltransferase 2 -3.15301
DEF6 differentially expressed in FDCP 6 homolog (mouse) -3.15301
ENTREP2 endosomal transmembrane epsin interactor 2 -2.94404
PIEZO2 piezo-type mechanosensitive ion channel component 2 -2.90761
ADAM32 ADAM metallopeptidase domain 32 -2.8814
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 -2.85062
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 -2.80781
CBR1 carbonyl reductase 1 -2.76973
CAND1 cullin-associated and neddylation-dissociated 1 -2.74427
ARHGAP27 Rho GTPase activating protein 27 -2.64363
HBQ1 hemoglobin, theta 1 -2.64363
SYBU syntabulin (syntaxin-interacting) -2.64363
NATD1 N-acetyltransferase domain containing 1 -2.64363
SEC24A SEC24 family member A -2.60414
TSLIG1 tRNA splicing ligase complex subunit 1 -2.57747
CCNB2 cyclin B2 -2.54687
AKIRIN2 akirin 2 -2.54033
UBALD1 UBA-like domain containing 1 -2.53688
HACD1 3-hydroxyacyl-CoA dehydratase 1 -2.53497
ZHX2 zinc fingers and homeoboxes 2 -2.47953
TENT5C terminal nucleotidyltransferase 5C -2.44906
PRSS27 protease, serine 27 -2.44906
ERBB4 erb-b2 receptor tyrosine kinase 4 -2.43794
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -2.41356
PHAF1 phagosome assembly factor 1 -2.38751
ZBED3 zinc finger, BED-type containing 3 -2.36391
H3C6 H3 clustered histone 6 -2.35605
CC2D1B coiled-coil and C2 domain containing 1B -2.35605
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 -2.33992
ABI2 abl-interactor 2 -2.33725
B2M beta-2-microglobulin -2.32781
SNAI1 snail family zinc finger 1 -2.3102
ARC activity-regulated cytoskeleton-associated protein -2.3102
FBXO15 F-box protein 15 -2.3102
RBM46 RNA binding motif protein 46 -2.3102
HIST1H2BF histone cluster 1, H2bf -2.3102
RAI1 retinoic acid induced 1 -2.3102
PAIP2 poly(A) binding protein interacting protein 2 -2.30779
PRDX3 peroxiredoxin 3 -2.29201
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 -2.2481
TMC7 transmembrane channel-like 7 -2.24755
GSAP gamma-secretase activating protein -2.22806
MBNL2 muscleblind-like splicing regulator 2 -2.21707
MTOR mechanistic target of rapamycin (serine/threonine kinase) -2.20314
TSPAN18 tetraspanin 18 -2.1344
P3H1 prolyl 3-hydroxylase 1 -2.11144
TMEM154 transmembrane protein 154 -2.10624
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa -2.10551
CREB3 cAMP responsive element binding protein 3 -2.08236
HDLBP high density lipoprotein binding protein -2.08008
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 -2.0729
CRLF1 cytokine receptor-like factor 1 -2.07191
PPP1R12C protein phosphatase 1, regulatory subunit 12C -2.06385
TRMT61B tRNA methyltransferase 61B -2.05905
GANC glucosidase, alpha; neutral C -2.05896
FZD6 frizzled class receptor 6 -2.05896
CAV2 caveolin 2 -2.05532
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 -2.04909
PABIR1 PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 -2.04546
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 -2.02994
ATG2A autophagy related 2A -2.02318
ACTR10 actin-related protein 10 homolog (S. cerevisiae) -2.01351