PHB Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description prohibitin|This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3' UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] (NCBI Entrez Gene Database, 5245)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_PHB
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Genes

123 co-expressed genes for PHB from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
AATF apoptosis antagonizing transcription factor
ADAM15 ADAM metallopeptidase domain 15
AFG3L2 AFG3-like AAA ATPase 2
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
BAHD1 bromo adjacent homology domain containing 1
BMS1 BMS1 ribosome biogenesis factor
BPHL biphenyl hydrolase-like (serine hydrolase)
BRD3 bromodomain containing 3
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CDC25C cell division cycle 25C
CHD3 chromodomain helicase DNA binding protein 3
CIB1 calcium and integrin binding 1 (calmyrin)
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CNPPD1 cyclin Pas1/PHO80 domain containing 1
COPS6 COP9 signalosome subunit 6
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CS citrate synthase
CSNK1D casein kinase 1, delta
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
DAXX death-domain associated protein
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8
DRG1 developmentally regulated GTP binding protein 1
DRG2 developmentally regulated GTP binding protein 2
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EBP emopamil binding protein (sterol isomerase)
EIF6 eukaryotic translation initiation factor 6
ELK1 ELK1, member of ETS oncogene family
EML3 echinoderm microtubule associated protein like 3
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1
ESYT1 extended synaptotagmin-like protein 1
FAM189B family with sequence similarity 189, member B
FANCG Fanconi anemia, complementation group G
FDXR ferredoxin reductase
GNL2 guanine nucleotide binding protein-like 2 (nucleolar)
GPAA1 glycosylphosphatidylinositol anchor attachment 1
GRK6 G protein-coupled receptor kinase 6
HMG20B high mobility group 20B
HNRNPL heterogeneous nuclear ribonucleoprotein L
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha
IFRD2 interferon-related developmental regulator 2
IGSF9B immunoglobulin superfamily, member 9B
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
ILF2 interleukin enhancer binding factor 2
ILVBL ilvB (bacterial acetolactate synthase)-like
KAT2A K(lysine) acetyltransferase 2A
KIAA0195 KIAA0195
LSM12 LSM12 homolog (S. cerevisiae)
MCRS1 microspherule protein 1
MEA1 male-enhanced antigen 1
METAP1 methionyl aminopeptidase 1
MFN2 mitofusin 2
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MLEC malectin
MPST mercaptopyruvate sulfurtransferase
MRPL28 mitochondrial ribosomal protein L28
MTX1 metaxin 1
NAP1L4 nucleosome assembly protein 1-like 4
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NELFB negative elongation factor complex member B
NFRKB nuclear factor related to kappaB binding protein
NFYB nuclear transcription factor Y, beta
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3
NUP188 nucleoporin 188kDa
NUP62 nucleoporin 62kDa
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1
PABPN1 poly(A) binding protein, nuclear 1
PARN poly(A)-specific ribonuclease
PAX8 paired box 8
PCBP3 poly(rC) binding protein 3
PCGF1 polycomb group ring finger 1
PCGF2 polycomb group ring finger 2
PFDN1 prefoldin subunit 1
PHB prohibitin
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PLIN3 perilipin 3
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKCSH protein kinase C substrate 80K-H
PRPF8 pre-mRNA processing factor 8
PSD4 pleckstrin and Sec7 domain containing 4
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PWP1 PWP1 homolog (S. cerevisiae)
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RBBP8 retinoblastoma binding protein 8
RPA2 replication protein A2, 32kDa
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SCARB1 scavenger receptor class B, member 1
SFSWAP splicing factor, suppressor of white-apricot family
SH2B1 SH2B adaptor protein 1
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
SPRN shadow of prion protein homolog (zebrafish)
SRRT serrate, RNA effector molecule
STK19 serine/threonine kinase 19
TCOF1 Treacher Collins-Franceschetti syndrome 1
TERF2IP telomeric repeat binding factor 2, interacting protein
TEX261 testis expressed 261
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TOMM34 translocase of outer mitochondrial membrane 34
TP53BP1 tumor protein p53 binding protein 1
TPR translocated promoter region, nuclear basket protein
TSTA3 tissue specific transplantation antigen P35B
TUBGCP2 tubulin, gamma complex associated protein 2
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VARS valyl-tRNA synthetase
WDR18 WD repeat domain 18
WDR62 WD repeat domain 62
XPO6 exportin 6
ZBED1 zinc finger, BED-type containing 1
ZNF271P zinc finger protein 271, pseudogene
ZPR1 ZPR1 zinc finger