PHB2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description prohibitin 2| (NCBI Entrez Gene Database, 11331)
External Link https://ncbi.nlm.nih.gov/gene/11331
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Genes

499 genes differentially expressed following the PHB2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.0286118
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.0254132
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 0.023487
STC2 stanniocalcin 2 0.0231693
PSAT1 phosphoserine aminotransferase 1 0.022484
S100P S100 calcium binding protein P 0.0200796
DDIT4 DNA-damage-inducible transcript 4 0.0196398
TRIB3 tribbles pseudokinase 3 0.0190278
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.017331
ASS1 argininosuccinate synthase 1 0.0171579
CBS cystathionine-beta-synthase 0.016984
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 0.0169437
XBP1 X-box binding protein 1 0.0162169
PHGDH phosphoglycerate dehydrogenase 0.0158874
GARS1 glycyl-tRNA synthetase 1 0.0157645
YARS1 tyrosyl-tRNA synthetase 1 0.0153609
TFF1 trefoil factor 1 0.0142077
WARS1 tryptophanyl-tRNA synthetase 1 0.0141214
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.0139498
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 0.0132611
XPOT exportin, tRNA 0.0132112
IARS1 isoleucyl-tRNA synthetase 1 0.0129629
SLC38A1 solute carrier family 38, member 1 0.0129546
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 0.0123649
ATF4 activating transcription factor 4 0.0116931
DDIT3 DNA-damage-inducible transcript 3 0.0115327
SARS1 seryl-tRNA synthetase 1 0.0112926
VEGFA vascular endothelial growth factor A 0.0110997
TSC22D3 TSC22 domain family, member 3 0.0110312
LCN2 lipocalin 2 0.0106475
CTH cystathionine gamma-lyase 0.0105934
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.0105793
IFITM1 interferon induced transmembrane protein 1 0.0105572
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.010522
MARS1 methionyl-tRNA synthetase 1 0.0103969
IFI44L interferon-induced protein 44-like 0.0103749
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 0.0103537
SIRT3 sirtuin 3 0.01035
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.0103219
GDF15 growth differentiation factor 15 0.0103149
AARS1 alanyl-tRNA synthetase 1 0.0102835
LEF1 lymphoid enhancer-binding factor 1 0.0101995
MOCOS molybdenum cofactor sulfurase 0.00992936
S100A12 S100 calcium binding protein A12 0.00991446
NUPR1 nuclear protein, transcriptional regulator, 1 0.00991364
INHBE inhibin, beta E 0.009873
CFB complement factor B 0.00979946
LYZ lysozyme 0.00978429
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.00959016
PYCR1 pyrroline-5-carboxylate reductase 1 0.00948438
AGR2 anterior gradient 2 0.00944623
NARS1 asparaginyl-tRNA synthetase 1 0.00926733
C6ORF48 chromosome 6 open reading frame 48 0.00922012
TARS1 threonyl-tRNA synthetase 1 0.00911635
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.00908875
ZMIZ1 zinc finger, MIZ-type containing 1 0.0090523
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.00902511
GRB10 growth factor receptor-bound protein 10 0.00898849
GTPBP2 GTP binding protein 2 0.00893593
DDR2 discoidin domain receptor tyrosine kinase 2 0.00889941
SMAD3 SMAD family member 3 0.00881137
ABLIM1 actin binding LIM protein 1 0.00877047
CARS1 cysteinyl-tRNA synthetase 1 0.0087327
IFRD1 interferon-related developmental regulator 1 0.00871584
NID2 nidogen 2 (osteonidogen) 0.0087035
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) 0.00850363
G0S2 G0/G1 switch 2 0.00849927
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 0.00845302
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.0084467
VLDLR very low density lipoprotein receptor 0.00835084
PSPH phosphoserine phosphatase 0.00830002
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.00822552
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.00819439
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.00818245
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.00814283
MX2 MX dynamin-like GTPase 2 0.00808942
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00808102
TGIF1 TGFB-induced factor homeobox 1 0.00807471
TBC1D16 TBC1 domain family, member 16 0.00806933
IFITM2 interferon induced transmembrane protein 2 0.00803583
MX1 MX dynamin-like GTPase 1 0.0080018
SH3YL1 SH3 and SYLF domain containing 1 0.00796228
NTS neurotensin 0.00792407
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00776476
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 0.00770823
OLFM4 olfactomedin 4 0.00768108
DUOX2 dual oxidase 2 0.00767484
TRIB2 tribbles pseudokinase 2 0.00767347
COL11A1 collagen, type XI, alpha 1 0.00765163
GPX2 glutathione peroxidase 2 0.00759986
RSAD2 radical S-adenosyl methionine domain containing 2 0.00758252
GTF2IRD1 GTF2I repeat domain containing 1 0.00758232
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.00756355
AKR1C3 aldo-keto reductase family 1, member C3 0.0075353
CCPG1 cell cycle progression 1 0.00753016
AREG amphiregulin 0.0074492
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 0.00739689
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.00737764
SCG5 secretogranin V 0.00732477
CXCL11 chemokine (C-X-C motif) ligand 11 0.00729155
KLF9 Kruppel-like factor 9 0.00725681
MET MET proto-oncogene, receptor tyrosine kinase 0.00722414
LCK LCK proto-oncogene, Src family tyrosine kinase 0.00719436
ZSCAN18 zinc finger and SCAN domain containing 18 0.00717645
VSNL1 visinin-like 1 0.00713729
TRIM22 tripartite motif containing 22 0.00710258
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 0.00709717
XAF1 XIAP associated factor 1 0.00706131
WIPI1 WD repeat domain, phosphoinositide interacting 1 0.00705679
JCHAIN joining chain of multimeric IgA and IgM 0.00695531
KAZN kazrin, periplakin interacting protein 0.00694992
FABP1 fatty acid binding protein 1, liver 0.00694974
RPIA ribose 5-phosphate isomerase A 0.00694278
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.00694041
IRF9 interferon regulatory factor 9 0.00693332
REG3A regenerating islet-derived 3 alpha 0.00692026
NMRK1 nicotinamide riboside kinase 1 0.00690743
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.00690493
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 0.00690058
PCOLCE procollagen C-endopeptidase enhancer 0.00689877
HSPA13 heat shock protein 70kDa family, member 13 0.00687774
XYLT1 xylosyltransferase I 0.00687419
THAP9-AS1 THAP9 antisense RNA 1 0.00687049
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.00686452
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.0068313
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 0.00681105
MID1IP1 MID1 interacting protein 1 0.00679528
EPHB2 EPH receptor B2 0.00676712
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 0.00675754
ZNF91 zinc finger protein 91 0.00675446
STK39 serine threonine kinase 39 0.00669497
PTCH1 patched 1 0.00669464
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00664722
NFIL3 nuclear factor, interleukin 3 regulated 0.00660551
DEFA6 defensin, alpha 6, Paneth cell-specific 0.0065293
MED13 mediator complex subunit 13 0.00652753
SULF1 sulfatase 1 0.00652619
ADIRF adipogenesis regulatory factor 0.00651877
CLIC4 chloride intracellular channel 4 0.00650795
AOC1 amine oxidase, copper containing 1 0.00650679
ATP10B ATPase, class V, type 10B 0.00647215
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00644883
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.00640619
CNTN1 contactin 1 0.00639918
TFF3 trefoil factor 3 (intestinal) 0.00635267
RSL24D1 ribosomal L24 domain containing 1 0.00635175
CLC Charcot-Leyden crystal galectin 0.00634044
LARP6 La ribonucleoprotein domain family, member 6 0.00627898
CADPS2 Ca++-dependent secretion activator 2 0.00627376
GREM1 gremlin 1, DAN family BMP antagonist 0.00626411
IFITM3 interferon induced transmembrane protein 3 0.00626333
CDH17 cadherin 17, LI cadherin (liver-intestine) 0.00623932
PDGFD platelet derived growth factor D 0.00621587
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00617843
KRCC1 lysine-rich coiled-coil 1 0.00616451
PHACTR2 phosphatase and actin regulator 2 0.00614881
ZCCHC8 zinc finger, CCHC domain containing 8 0.00614694
PXDN peroxidasin 0.00613139
SYT1 synaptotagmin I 0.00612185
RCAN1 regulator of calcineurin 1 0.00611157
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 0.00611124
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00611001
GSE1 Gse1 coiled-coil protein 0.00610328
CCDC92 coiled-coil domain containing 92 0.00610099
JMJD1C jumonji domain containing 1C 0.00608909
IFI44 interferon-induced protein 44 0.00607628
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.00604805
MBNL2 muscleblind-like splicing regulator 2 0.00602771
SYBU syntabulin (syntaxin-interacting) 0.0060253
PTP4A2 protein tyrosine phosphatase type IVA, member 2 0.00602278
CEMIP cell migration inducing protein, hyaluronan binding 0.00601999
LOX lysyl oxidase 0.00601094
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 0.00600833
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.0060021
GSAP gamma-secretase activating protein 0.00599615
IGFBP1 insulin-like growth factor binding protein 1 0.00596937
LAMB1 laminin, beta 1 0.00596872
H1-0 H1.0 linker histone 0.00596613
HBD hemoglobin, delta 0.00595242
DPEP1 dipeptidase 1 (renal) 0.00594532
KRT20 keratin 20, type I 0.0059417
NAV2 neuron navigator 2 0.00593058
R3HDM2 R3H domain containing 2 0.00592898
MTMR11 myotubularin related protein 11 0.00591607
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.00591419
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 0.00591244
REG1A regenerating islet-derived 1 alpha 0.00589673
SPG11 spastic paraplegia 11 (autosomal recessive) 0.00589607
SMC6 structural maintenance of chromosomes 6 0.00588689
NELL2 NEL-like 2 (chicken) 0.00588667
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 0.00586459
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.00585596
BLNK B-cell linker 0.0058178
LRRC8D leucine rich repeat containing 8 family, member D 0.00576769
PLBD1 phospholipase B domain containing 1 0.00575444
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.00574699
KLF2 Kruppel-like factor 2 0.00573397
DEFA5 defensin, alpha 5, Paneth cell-specific 0.00572558
HAX1 HCLS1 associated protein X-1 0.00571282
ACSL5 acyl-CoA synthetase long-chain family member 5 0.0057046
COMP cartilage oligomeric matrix protein 0.00570026
RNF43 ring finger protein 43 0.00568168
FAM120A family with sequence similarity 120A 0.00567819
CUX1 cut-like homeobox 1 0.00565293
CPT1A carnitine palmitoyltransferase 1A (liver) 0.00563942
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.0056377
TRIO trio Rho guanine nucleotide exchange factor 0.00563655
PITX3 paired-like homeodomain 3 0.00562062
CPE carboxypeptidase E 0.00561865
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.00561595
POU2AF1 POU class 2 associating factor 1 0.00560001
MFAP5 microfibrillar associated protein 5 0.00559054
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) 0.00555455
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.00552679
ABAT 4-aminobutyrate aminotransferase 0.00551302
HEPH hephaestin 0.00550498
KANK1 KN motif and ankyrin repeat domains 1 0.00550175
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 0.00549151
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00548806
CLCN4 chloride channel, voltage-sensitive 4 0.00548194
DMTF1 cyclin D binding myb-like transcription factor 1 0.00547813
RGS5 regulator of G-protein signaling 5 0.00546437
NAV3 neuron navigator 3 0.00544759
IFI27 interferon, alpha-inducible protein 27 0.00544701
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.00544488
ELP1 elongator acetyltransferase complex subunit 1 0.00541854
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.00541515
ARHGAP5 Rho GTPase activating protein 5 0.0054137
EIF1 eukaryotic translation initiation factor 1 0.00538821
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.00537752
PTK2 protein tyrosine kinase 2 0.00537657
TMEM106B transmembrane protein 106B 0.005334
TRPA1 transient receptor potential cation channel, subfamily A, member 1 0.00533263
MARCKSL1 MARCKS-like 1 0.00532987
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) 0.00532443
APOL6 apolipoprotein L, 6 0.00531512
SKAP2 src kinase associated phosphoprotein 2 0.00531369
TRIM37 tripartite motif containing 37 0.00531153
NIBAN1 niban apoptosis regulator 1 0.00528728
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.00528562
EPB41L4B erythrocyte membrane protein band 4.1 like 4B 0.00528282
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00527791
SELE selectin E 0.00525838
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 0.00524852
PFN2 profilin 2 0.00524735
S100A6 S100 calcium binding protein A6 0.00523759
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.00522903
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 0.00521891
LGALS4 lectin, galactoside-binding, soluble, 4 0.00521096
TRPS1 trichorhinophalangeal syndrome I 0.00520585

decreased expression

Symbol Name Standardized Value
HSPA1A heat shock 70kDa protein 1A -0.0157342
FABP7 fatty acid binding protein 7, brain -0.0134273
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.0109504
HOPX HOP homeobox -0.0104666
TMEM45A transmembrane protein 45A -0.0104417
TAGLN2 transgelin 2 -0.00989689
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00960092
NLRP2 NLR family, pyrin domain containing 2 -0.00932855
RTN2 reticulon 2 -0.00923127
H2AX H2A.X variant histone -0.00891231
BAD BCL2-associated agonist of cell death -0.00881953
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -0.0085413
TGM2 transglutaminase 2 -0.00853499
CLU clusterin -0.00811013
CLDN8 claudin 8 -0.0080739
CES1 carboxylesterase 1 -0.00805256
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00802807
CDCA4 cell division cycle associated 4 -0.00794107
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.0076467
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00764524
CD44 CD44 molecule (Indian blood group) -0.00764136
SDC4 syndecan 4 -0.00764078
MEIS2 Meis homeobox 2 -0.00763293
CRELD2 cysteine-rich with EGF-like domains 2 -0.007565
SLC43A3 solute carrier family 43, member 3 -0.00754692
UBE2S ubiquitin-conjugating enzyme E2S -0.00751533
MYBPC1 myosin binding protein C, slow type -0.00747745
SPARCL1 SPARC-like 1 (hevin) -0.00744503
CD59 CD59 molecule, complement regulatory protein -0.00740296
CXADR coxsackie virus and adenovirus receptor -0.00735288
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.00730984
ATOX1 antioxidant 1 copper chaperone -0.00729702
KRT7 keratin 7, type II -0.00728726
HSPA8 heat shock 70kDa protein 8 -0.0072554
BAMBI BMP and activin membrane-bound inhibitor -0.00724874
COCH cochlin -0.00713641
ERGIC2 ERGIC and golgi 2 -0.00702197
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00700403
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00699511
CDC42 cell division cycle 42 -0.0069596
EDN3 endothelin 3 -0.00691262
CST6 cystatin E/M -0.00690694
CETN2 centrin, EF-hand protein, 2 -0.0068817
NSDHL NAD(P) dependent steroid dehydrogenase-like -0.00680601
TFRC transferrin receptor -0.00678524
HSPB1 heat shock 27kDa protein 1 -0.00670138
BHLHE41 basic helix-loop-helix family, member e41 -0.00667464
AK4 adenylate kinase 4 -0.00666264
MAGEA3 melanoma antigen family A3 -0.0066498
RDX radixin -0.00664474
PLK1 polo-like kinase 1 -0.00663285
HSPB8 heat shock 22kDa protein 8 -0.00663063
FASN fatty acid synthase -0.00663025
TMEM100 transmembrane protein 100 -0.00659545
NCALD neurocalcin delta -0.00653744
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -0.00652625
EMP3 epithelial membrane protein 3 -0.00650074
MED6 mediator complex subunit 6 -0.00649811
EXT1 exostosin glycosyltransferase 1 -0.00649029
CADM1 cell adhesion molecule 1 -0.00648399
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00647474
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -0.00647184
CSRP2 cysteine and glycine-rich protein 2 -0.00646904
SLPI secretory leukocyte peptidase inhibitor -0.00646782
KDM3A lysine (K)-specific demethylase 3A -0.0064285
COL6A2 collagen, type VI, alpha 2 -0.00637945
TKTL1 transketolase-like 1 -0.00634046
CYTL1 cytokine-like 1 -0.00632473
IDI1 isopentenyl-diphosphate delta isomerase 1 -0.00631719
MEF2C myocyte enhancer factor 2C -0.00631423
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 -0.00630014
C1ORF115 chromosome 1 open reading frame 115 -0.00628749
SFTPC surfactant protein C -0.00625547
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.00623054
BCAP31 B-cell receptor-associated protein 31 -0.0061837
MAGEA12 melanoma antigen family A12 -0.00616948
DMD dystrophin -0.00615839
CCNE2 cyclin E2 -0.00615575
REEP1 receptor accessory protein 1 -0.00614757
MSMB microseminoprotein, beta- -0.00613321
PON2 paraoxonase 2 -0.00612866
TUBB2A tubulin, beta 2A class IIa -0.00612197
EGR3 early growth response 3 -0.00611999
RRM2 ribonucleotide reductase M2 -0.00610954
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 -0.0060596
CDC25A cell division cycle 25A -0.00605591
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.0060314
CCL2 chemokine (C-C motif) ligand 2 -0.00601399
FZD5 frizzled class receptor 5 -0.00601322
TUBB4B tubulin, beta 4B class IVb -0.00600451
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -0.00600005
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.00598147
FEN1 flap structure-specific endonuclease 1 -0.00594269
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.00594037
GRB14 growth factor receptor-bound protein 14 -0.00593703
LOR loricrin -0.00593606
CPM carboxypeptidase M -0.00592604
MSMO1 methylsterol monooxygenase 1 -0.00591711
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -0.00586715
SCGB2A1 secretoglobin, family 2A, member 1 -0.00586534
ANOS1 anosmin 1 -0.00586227
FLNA filamin A, alpha -0.00585563
TMEM87A transmembrane protein 87A -0.00583065
WWTR1 WW domain containing transcription regulator 1 -0.00582788
HSPE1 heat shock 10kDa protein 1 -0.00582274
CHP1 calcineurin-like EF-hand protein 1 -0.00581665
FASTKD5 FAST kinase domains 5 -0.00581617
NUSAP1 nucleolar and spindle associated protein 1 -0.00579029
C20ORF27 chromosome 20 open reading frame 27 -0.00578483
MAGEA1 melanoma antigen family A1 -0.00575863
HMGN3 high mobility group nucleosomal binding domain 3 -0.00575128
RRAD Ras-related associated with diabetes -0.00571103
P4HB prolyl 4-hydroxylase, beta polypeptide -0.00570418
ACTG2 actin, gamma 2, smooth muscle, enteric -0.00569134
ALOX15B arachidonate 15-lipoxygenase, type B -0.00568414
BANF1 barrier to autointegration factor 1 -0.00564323
NT5DC2 5'-nucleotidase domain containing 2 -0.00560287
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 -0.00559783
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.0055903
AQP3 aquaporin 3 (Gill blood group) -0.00558044
COL7A1 collagen, type VII, alpha 1 -0.0055802
REEP5 receptor accessory protein 5 -0.00557143
PCOLCE2 procollagen C-endopeptidase enhancer 2 -0.00556726
AP1S1 adaptor-related protein complex 1, sigma 1 subunit -0.00556388
UBE2E3 ubiquitin-conjugating enzyme E2E 3 -0.00555371
HILPDA hypoxia inducible lipid droplet-associated -0.0055349
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00553224
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.00553081
TACSTD2 tumor-associated calcium signal transducer 2 -0.00551127
SIVA1 SIVA1, apoptosis-inducing factor -0.00550462
CRYBG1 crystallin beta-gamma domain containing 1 -0.00548976
EGR1 early growth response 1 -0.00547096
CHKB choline kinase beta -0.00546202
ORC1 origin recognition complex, subunit 1 -0.00545587
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) -0.00545523
FOLR1 folate receptor 1 (adult) -0.00544904
G6PD glucose-6-phosphate dehydrogenase -0.00539021
CCNA2 cyclin A2 -0.0053868
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.00537812
GUK1 guanylate kinase 1 -0.00537341
ATP5MG ATP synthase membrane subunit g -0.00537144
SHCBP1 SHC SH2-domain binding protein 1 -0.00535332
SEC61G Sec61 gamma subunit -0.00534404
NCAPD3 non-SMC condensin II complex, subunit D3 -0.00534218
EIF4E2 eukaryotic translation initiation factor 4E family member 2 -0.00533852
ZNF589 zinc finger protein 589 -0.00533598
EGR2 early growth response 2 -0.00533353
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 -0.00533177
CD1E CD1e molecule -0.00532271
RGS10 regulator of G-protein signaling 10 -0.00530939
GPR88 G protein-coupled receptor 88 -0.00530145
RAB38 RAB38, member RAS oncogene family -0.00528842
IL27RA interleukin 27 receptor, alpha -0.00527659
PLN phospholamban -0.00527568
CKS2 CDC28 protein kinase regulatory subunit 2 -0.00525987
SFRP1 secreted frizzled-related protein 1 -0.00524513
VAMP8 vesicle-associated membrane protein 8 -0.00524246
ILF2 interleukin enhancer binding factor 2 -0.00523029
MARCO macrophage receptor with collagenous structure -0.00522604
DSG1 desmoglein 1 -0.00521618
ASRGL1 asparaginase like 1 -0.00520579
GRWD1 glutamate-rich WD repeat containing 1 -0.00520335
SDF4 stromal cell derived factor 4 -0.00520006
PCNA proliferating cell nuclear antigen -0.00517638
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -0.00515521
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -0.00514513
TUBA1A tubulin, alpha 1a -0.00513269
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) -0.00513024
RFWD3 ring finger and WD repeat domain 3 -0.00512603
NRBP1 nuclear receptor binding protein 1 -0.00511845
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -0.00511238
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) -0.00510771
PXMP4 peroxisomal membrane protein 4, 24kDa -0.00509879
WDR26 WD repeat domain 26 -0.00508217
TLCD3A TLC domain containing 3A -0.00507961
SDF2L1 stromal cell-derived factor 2-like 1 -0.00507297
BMPR1A bone morphogenetic protein receptor, type IA -0.00506192
CD99 CD99 molecule -0.00506181
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) -0.00505514
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -0.0050539
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -0.00504867
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 -0.00503672
CHERP calcium homeostasis endoplasmic reticulum protein -0.00502076
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -0.0050114
UGCG UDP-glucose ceramide glucosyltransferase -0.00500889
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 -0.00500223
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa -0.00499836
IER5 immediate early response 5 -0.00499455
UBAP2L ubiquitin associated protein 2-like -0.00499375
SFTPD surfactant protein D -0.00498325
PON3 paraoxonase 3 -0.0049763
LRP4 low density lipoprotein receptor-related protein 4 -0.00497003
SCARB1 scavenger receptor class B, member 1 -0.00496682
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa -0.00496206
L1CAM L1 cell adhesion molecule -0.00495945
ANO1 anoctamin 1, calcium activated chloride channel -0.00495888
AQP4 aquaporin 4 -0.00495098
NCAPD2 non-SMC condensin I complex, subunit D2 -0.0049472
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 -0.00494673
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.00494516
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.00494501
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -0.00494221
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -0.00493286
H1-2 H1.2 linker histone, cluster member -0.00493014
S100A10 S100 calcium binding protein A10 -0.00491732
CFAP20 cilia and flagella associated protein 20 -0.00491389
ENO1 enolase 1, (alpha) -0.00491348
LMO3 LIM domain only 3 (rhombotin-like 2) -0.00490803
STIP1 stress-induced phosphoprotein 1 -0.00490376
S100A7 S100 calcium binding protein A7 -0.00490016
CAVIN1 caveolae associated protein 1 -0.00489331
COBL cordon-bleu WH2 repeat protein -0.0048917
PRDX4 peroxiredoxin 4 -0.00488109
MRPL20 mitochondrial ribosomal protein L20 -0.00487473
EGLN3 egl-9 family hypoxia-inducible factor 3 -0.00487253
NOTCH2 notch 2 -0.00486871
RTL8C retrotransposon Gag like 8C -0.00485908
AAMP angio-associated, migratory cell protein -0.00485244
TSPO translocator protein (18kDa) -0.00484763
RRAS2 related RAS viral (r-ras) oncogene homolog 2 -0.00484578
SERHL2 serine hydrolase-like 2 -0.0048413
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 -0.00484107
ZNF207 zinc finger protein 207 -0.00482327
FRMD4A FERM domain containing 4A -0.00481895
HAL histidine ammonia-lyase -0.00481325
ANAPC15 anaphase promoting complex subunit 15 -0.00479667
CXCR4 chemokine (C-X-C motif) receptor 4 -0.00478402
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 -0.00477888
MCM5 minichromosome maintenance complex component 5 -0.00477517
APOC1 apolipoprotein C-I -0.00476919
ZNF124 zinc finger protein 124 -0.00476839
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits -0.00476273
SINHCAF SIN3-HDAC complex associated factor -0.00475396
HABP2 hyaluronan binding protein 2 -0.00475136
GPX3 glutathione peroxidase 3 -0.00474515
DIO2 deiodinase, iodothyronine, type II -0.00473842
NFIB nuclear factor I/B -0.00473649
RNF125 ring finger protein 125, E3 ubiquitin protein ligase -0.00473508
ANGPT1 angiopoietin 1 -0.00472998
ZNF432 zinc finger protein 432 -0.00472974
PIP prolactin-induced protein -0.00471984
SFPQ splicing factor proline/glutamine-rich -0.00471609
FHOD3 formin homology 2 domain containing 3 -0.00469966
MFSD5 major facilitator superfamily domain containing 5 -0.00469588
BATF3 basic leucine zipper transcription factor, ATF-like 3 -0.00469552
RFC2 replication factor C (activator 1) 2, 40kDa -0.00469435
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -0.00469341
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 -0.00469278
FSCN1 fascin actin-bundling protein 1 -0.00468469