PHC1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description polyhomeotic homolog 1 (Drosophila)|This gene is a homolog of the Drosophila polyhomeotic gene, which is a member of the Polycomb group of genes. The gene product is a component of a multimeric protein complex that contains EDR2 and the vertebrate Polycomb protein BMH1. The gene product, the EDR2 protein, and the Drosophila polyhomeotic protein share 2 highly conserved domains, named homology domains I and II. These domains are involved in protein-protein interactions and may mediate heterodimerization of the protein encoded by this gene and the EDR2 protein. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1911)
External Link http://www.ncbi.nlm.nih.gov/gene/1911
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67 interacting proteins for PHC1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
BMI1 BMI1 proto-oncogene, polycomb ring finger
CBX2 chromobox homolog 2
CBX4 chromobox homolog 4
CBX6 chromobox homolog 6
CBX7 chromobox homolog 7
CBX8 chromobox homolog 8
CCDC158 coiled-coil domain containing 158
CENPF centromere protein F, 350/400kDa
CHD7 chromodomain helicase DNA binding protein 7
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
CSNK2B casein kinase 2, beta polypeptide
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
EED embryonic ectoderm development
ELAVL1 ELAV like RNA binding protein 1
ERCC6 excision repair cross-complementation group 6
FER fer (fps/fes related) tyrosine kinase
GMNN geminin, DNA replication inhibitor
HDAC2 histone deacetylase 2
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1
HIST1H1A histone cluster 1, H1a
HIST1H4F histone cluster 1, H4f
HSPA1B heat shock 70kDa protein 1B
HSPA8 heat shock 70kDa protein 8
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
MAPK11 mitogen-activated protein kinase 11
MAPK14 mitogen-activated protein kinase 14
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MDM1 Mdm1 nuclear protein homolog (mouse)
MKI67 marker of proliferation Ki-67
MOV10 Mov10 RISC complex RNA helicase
PCGF2 polycomb group ring finger 2
PCGF6 polycomb group ring finger 6
PHC2 polyhomeotic homolog 2 (Drosophila)
PHC3 polyhomeotic homolog 3 (Drosophila)
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
RING1 ring finger protein 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF17 ring finger protein 17
RNF2 ring finger protein 2
RUVBL2 RuvB-like AAA ATPase 2
RYBP RING1 and YY1 binding protein
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SCML1 sex comb on midleg-like 1 (Drosophila)
SFMBT1 Scm-like with four mbt domains 1
SFN stratifin
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMC3 structural maintenance of chromosomes 3
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
STAMBPL1 STAM binding protein-like 1
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBE2I ubiquitin-conjugating enzyme E2I
USP11 ubiquitin specific peptidase 11
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
WDHD1 WD repeat and HMG-box DNA binding protein 1
YAF2 YY1 associated factor 2
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
YY1 YY1 transcription factor
ZNF546 zinc finger protein 546