PHF1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description PHD finger protein 1|This gene encodes a Polycomb group protein. The protein is a component of a histone H3 lysine-27 (H3K27)-specific methyltransferase complex, and functions in transcriptional repression of homeotic genes. The protein is also recruited to double-strand breaks, and reduced protein levels results in X-ray sensitivity and increased homologous recombination. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] (NCBI Entrez Gene Database, 5252)
External Link http://www.ncbi.nlm.nih.gov/gene/5252
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Genes

26 interacting proteins for PHF1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
CUL4B cullin 4B
DDB1 damage-specific DNA binding protein 1, 127kDa
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DYSF dysferlin
EED embryonic ectoderm development
ELAVL1 ELAV like RNA binding protein 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
H3F3A H3 histone, family 3A
HIC1 hypermethylated in cancer 1
HIST1H3B histone cluster 1, H3b
HIST2H3A histone cluster 2, H3a
JARID2 jumonji, AT rich interactive domain 2
NCR1 natural cytotoxicity triggering receptor 1
NEK6 NIMA-related kinase 6
RAD50 RAD50 homolog (S. cerevisiae)
RBBP7 retinoblastoma binding protein 7
RBPMS RNA binding protein with multiple splicing
SMC1A structural maintenance of chromosomes 1A
SUMO1 small ubiquitin-like modifier 1
SUZ12 SUZ12 polycomb repressive complex 2 subunit
TFCP2 transcription factor CP2
THAP1 THAP domain containing, apoptosis associated protein 1
TP53 tumor protein p53
UBC ubiquitin C
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6