PHF10 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description PHD finger protein 10|This gene contains a predicted ORF that encodes a protein with two zinc finger domains. The function of the encoded protein is not known. Sequence analysis suggests that multiple alternatively spliced transcript variants are derived from this gene but the full-length nature of only two of them is known. These two splice variants encode different isoforms. A pseudogene for this gene is located on Xq28. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 55274)
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Genes

340 genes differentially expressed following the PHF10 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
LOC390937 Ets2 repressor factor-like 2.56336
NAPSA napsin A aspartic peptidase 2.56336
TXLNB taxilin beta 2.56336
TRH thyrotropin-releasing hormone 2.56336
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 2.56336
KLRK1 killer cell lectin-like receptor subfamily K, member 1 2.56336
CD1D CD1d molecule 2.56336
TMEM176A transmembrane protein 176A 2.56336
MUC1 mucin 1, cell surface associated 2.56336
RAX retina and anterior neural fold homeobox 2.56336
ZNF468 zinc finger protein 468 2.56336
TMEM151A transmembrane protein 151A 2.56336
LAPTM5 lysosomal protein transmembrane 5 2.56336
TMPRSS11A transmembrane protease, serine 11A 2.56336
SIX3 SIX homeobox 3 2.56336
ACTRT1 actin-related protein T1 2.56336
OR2A25 olfactory receptor, family 2, subfamily A, member 25 2.56336
CYP26C1 cytochrome P450, family 26, subfamily C, polypeptide 1 2.56336
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 2.56336
TBX20 T-box 20 2.56336
ZNF98 zinc finger protein 98 2.56336
SYCP1 synaptonemal complex protein 1 2.56336
SYCP2 synaptonemal complex protein 2 2.56336
KLHL35 kelch-like family member 35 2.56336
WEE2 WEE1 homolog 2 (S. pombe) 2.56336
HNF4A hepatocyte nuclear factor 4, alpha 2.56336
OR2B6 olfactory receptor, family 2, subfamily B, member 6 2.56336
OPRL1 opiate receptor-like 1 2.56336
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 2.56336
OR4D9 olfactory receptor, family 4, subfamily D, member 9 2.56336
OIT3 oncoprotein induced transcript 3 2.56336
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 2.56336
HES2 hes family bHLH transcription factor 2 2.56336
TMEM39B transmembrane protein 39B 2.56336
SPAG8 sperm associated antigen 8 2.56336
FAM9B family with sequence similarity 9, member B 2.56336
LOC102724877 uncharacterized LOC102724877 2.56336
STAP1 signal transducing adaptor family member 1 2.56336
RAMP3 receptor (G protein-coupled) activity modifying protein 3 2.56336
MPL MPL proto-oncogene, thrombopoietin receptor 2.56336
CORO6 coronin 6 2.56336
FST follistatin 2.56336
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 2.56336
GPR26 G protein-coupled receptor 26 2.56336
ADAD2 adenosine deaminase domain containing 2 2.56336
RFPL2 ret finger protein-like 2 2.56336
TPSD1 tryptase delta 1 2.56336
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 2.56336
TDRD9 tudor domain containing 9 2.56336
MGARP mitochondria-localized glutamic acid-rich protein 2.56336
NUDT10 nudix (nucleoside diphosphate linked moiety X)-type motif 10 2.56336
RIMBP3C RIMS binding protein 3C 2.56336
CRYGA crystallin, gamma A 2.56336
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 2.56336
SPMIP9 sperm microtubule inner protein 9 2.56336
MCHR1 melanin-concentrating hormone receptor 1 2.56336
ADGRG3 adhesion G protein-coupled receptor G3 2.56336
MLN motilin 2.56336
SMLR1 small leucine-rich protein 1 2.56336
C1QTNF9B C1q and tumor necrosis factor related protein 9B 2.56336
TREX2 three prime repair exonuclease 2 2.56336
NHLH1 nescient helix loop helix 1 2.56336
ASB9 ankyrin repeat and SOCS box containing 9 2.56336
SRPK3 SRSF protein kinase 3 2.56336
MYEOV myeloma overexpressed 2.56336
TSPAN1 tetraspanin 1 2.56336
PCDHGA9 protocadherin gamma subfamily A, 9 2.56336
STAT4 signal transducer and activator of transcription 4 2.56336
PNMA8B PNMA family member 8B 2.56336
PNMA6F PNMA family member 6F 2.56336
LITAFD LITAF domain containing 2.56336
FAM240A family with sequence similarity 240 member A 2.56336
LOC124906010 uncharacterized LOC124906010 2.56336
TMEM272 transmembrane protein 272 2.56336
CLEC20A C-type lectin domain containing 20A 2.56336
CPHXL cytoplasmic polyadenylated homeobox like 2.56336
TBXT T-box transcription factor T 2.56336
SMIM41 small integral membrane protein 41 2.56336
TTLL13 tubulin tyrosine ligase like 13 2.56336
CFAP65 cilia and flagella associated protein 65 2.56336
IMPG1 interphotoreceptor matrix proteoglycan 1 2.56336
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa 2.56336
LRIT3 leucine-rich repeat, immunoglobulin-like and transmembrane domains 3 2.56336
CXCL17 chemokine (C-X-C motif) ligand 17 2.56336
TMEM236 transmembrane protein 236 2.56336
SP140 SP140 nuclear body protein 2.56336
KRABD1 KRAB domain containing 1 2.56336
PEX12 peroxisomal biogenesis factor 12 2.56336
DSG1 desmoglein 1 2.56336
PTPRH protein tyrosine phosphatase, receptor type, H 2.56336
MTNR1B melatonin receptor 1B 2.56336
SLFN14 schlafen family member 14 2.56336
RAB44 RAB44, member RAS oncogene family 2.56336
SGK1 serum/glucocorticoid regulated kinase 1 2.56336
BHLHA9 basic helix-loop-helix family, member a9 2.56336
DYM dymeclin 2.56336
OSTN osteocrin 2.56336
HNF1A HNF1 homeobox A 2.56336
ZAR1L zygote arrest 1-like 2.56336
OR2D2 olfactory receptor, family 2, subfamily D, member 2 2.56336
SAMD15 sterile alpha motif domain containing 15 2.56336
TARM1 T cell-interacting, activating receptor on myeloid cells 1 2.56336
PRR4 proline rich 4 (lacrimal) 2.56336
C1QL3 complement component 1, q subcomponent-like 3 2.56336
OAF OAF homolog (Drosophila) 2.56336
C12ORF57 chromosome 12 open reading frame 57 2.56336
APOBEC4 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative) 2.56336
ZDBF2 zinc finger, DBF-type containing 2 2.56336
EMCN endomucin 2.56336
ALOX5AP arachidonate 5-lipoxygenase-activating protein 2.56336
TNR tenascin R 2.56336
DQX1 DEAQ box RNA-dependent ATPase 1 2.56336
BTNL2 butyrophilin-like 2 2.56336
ARR3 arrestin 3, retinal (X-arrestin) 2.56336
CXCR4 chemokine (C-X-C motif) receptor 4 2.56336
S100Z S100 calcium binding protein Z 2.56336
LRRIQ3 leucine-rich repeats and IQ motif containing 3 2.56336
MAP3K19 mitogen-activated protein kinase kinase kinase 19 2.56336
SCRN2 secernin 2 2.56336
TMED7 transmembrane emp24 protein transport domain containing 7 2.56336
SPIRE1 spire-type actin nucleation factor 1 2.56336
POF1B premature ovarian failure, 1B 2.56336
MAGEB17 melanoma antigen family B17 2.56336
CEACAM16 carcinoembryonic antigen-related cell adhesion molecule 16 2.56336
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 2.56336
NCR3LG1 natural killer cell cytotoxicity receptor 3 ligand 1 2.56336
MBOAT4 membrane bound O-acyltransferase domain containing 4 2.56336
PCDHGB2 protocadherin gamma subfamily B, 2 2.56336
LRRC46 leucine rich repeat containing 46 2.56336
ERICH6 glutamate-rich 6 2.56336
CT55 cancer/testis antigen 55 2.56336
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 2.56336
CPA2 carboxypeptidase A2 (pancreatic) 2.56336
B9D1 B9 protein domain 1 2.56336
SOSTDC1 sclerostin domain containing 1 2.56336
BCL2L15 BCL2-like 15 2.56336
PSG9 pregnancy specific beta-1-glycoprotein 9 2.56336
QRFP pyroglutamylated RFamide peptide 2.56336
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 2.56336
KLHDC1 kelch domain containing 1 2.56336
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 2.56336
OR52N2 olfactory receptor, family 52, subfamily N, member 2 2.56336
PHACTR3 phosphatase and actin regulator 3 2.56336
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.56336
SIGLEC11 sialic acid binding Ig-like lectin 11 2.56336
FCRLB Fc receptor-like B 2.56336
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 2.56336
SHISA8 shisa family member 8 2.56336
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 2.56336
OR2L3 olfactory receptor, family 2, subfamily L, member 3 2.56336
RGS8 regulator of G-protein signaling 8 2.56336
SPATA9 spermatogenesis associated 9 2.56336
ZC3H11D zinc finger CCCH-type containing 11D 2.56336
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 2.56336
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 2.56336
CLEC9A C-type lectin domain family 9, member A 2.56336
TRHR thyrotropin-releasing hormone receptor 2.56336
APOL4 apolipoprotein L, 4 2.56336
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 2.56336
AQP1 aquaporin 1 (Colton blood group) 2.56336
TMEM184A transmembrane protein 184A 2.56336
PPP1R3A protein phosphatase 1, regulatory subunit 3A 2.56336
RBP4 retinol binding protein 4, plasma 2.56336
GCM1 glial cells missing homolog 1 (Drosophila) 2.56336
PPP1R3G protein phosphatase 1, regulatory subunit 3G 2.56336
OR10G3 olfactory receptor, family 10, subfamily G, member 3 2.56336
TGM3 transglutaminase 3 2.56336
MAGEA10 melanoma antigen family A10 2.56336
MMRN2 multimerin 2 2.56336
ZC2HC1B zinc finger, C2HC-type containing 1B 2.56336
TEX36 testis expressed 36 2.56336
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) 2.56336
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 2.56336
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 2.56336
MMP3 matrix metallopeptidase 3 2.56336
ERAP2 endoplasmic reticulum aminopeptidase 2 2.56336
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 2.56336
STMND1 stathmin domain containing 1 2.56336
OSBPL11 oxysterol binding protein-like 11 2.56336
FAM25A family with sequence similarity 25, member A 2.56336
TMEM81 transmembrane protein 81 2.56336
TMEM156 transmembrane protein 156 2.56336
CDCP2 CUB domain containing protein 2 2.56336
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2.56336
PF4V1 platelet factor 4 variant 1 2.56336
ICAM2 intercellular adhesion molecule 2 2.56336
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 2.56336
GH1 growth hormone 1 2.56336
ANXA8 annexin A8 2.56336
IL33 interleukin 33 2.56336
HILPDA hypoxia inducible lipid droplet-associated 2.55769
DCLK1 doublecortin-like kinase 1 2.49342
TMEM9 transmembrane protein 9 2.49311
PRC1 protein regulator of cytokinesis 1 2.48664
TFE3 transcription factor binding to IGHM enhancer 3 2.48132
SSUH2 ssu-2 homolog (C. elegans) 2.45333
TMEM19 transmembrane protein 19 2.42634
GPNMB glycoprotein (transmembrane) nmb 2.42299
ZNF443 zinc finger protein 443 2.39543
GOLGA6L9 golgin A6 family-like 9 2.39516
CNKSR3 CNKSR family member 3 2.39432
VEGFA vascular endothelial growth factor A 2.39432
TMEM127 transmembrane protein 127 2.37362
LRRC14 leucine rich repeat containing 14 2.36164
SPAG16 sperm associated antigen 16 2.3555
NINJ1 ninjurin 1 2.32961
HEATR5A HEAT repeat containing 5A 2.32456
NT5C3A 5'-nucleotidase, cytosolic IIIA 2.31337
PARL presenilin associated, rhomboid-like 2.29041
SEPTIN8 septin 8 2.28467
DARS2 aspartyl-tRNA synthetase 2, mitochondrial 2.27525
TRAPPC1 trafficking protein particle complex 1 2.27525
NTPCR nucleoside-triphosphatase, cancer-related 2.26923
SELENOP selenoprotein P 2.2656
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 2.25653
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 2.25014
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 2.19151
CPNE1 copine I 2.18497
ZCCHC7 zinc finger, CCHC domain containing 7 2.18186
ZNF598 zinc finger protein 598 2.17515
NCOA3 nuclear receptor coactivator 3 2.15815
MTIF3 mitochondrial translational initiation factor 3 2.15183
POLH polymerase (DNA directed), eta 2.11876
PANX2 pannexin 2 2.1176
C1QTNF4 C1q and tumor necrosis factor related protein 4 2.1176
GARIN5A golgi associated RAB2 interactor 5A 2.10648
SOD3 superoxide dismutase 3, extracellular 2.10125
EDIL3 EGF-like repeats and discoidin I-like domains 3 2.0854
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 2.07611
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 2.06503
PHYH phytanoyl-CoA 2-hydroxylase 2.05931
HBEGF heparin-binding EGF-like growth factor 2.05445
WIPI1 WD repeat domain, phosphoinositide interacting 1 2.05445
PKD2 polycystic kidney disease 2 (autosomal dominant) 2.03843
SCAND3 SCAN domain containing 3 2.03378
B3GAT1 beta-1,3-glucuronyltransferase 1 2.03378
AGO4 argonaute RISC catalytic component 4 2.03053
HIPK2 homeodomain interacting protein kinase 2 2.02235
DPCD deleted in primary ciliary dyskinesia homolog (mouse) 2.02235
RBKS ribokinase 2.02169
LRRIQ1 leucine-rich repeats and IQ motif containing 1 2.01743
MEPCE methylphosphate capping enzyme 2.01166
DYNLL2 dynein, light chain, LC8-type 2 2.01166

decreased expression

Symbol Name Standardized Value
UBE2L5 ubiquitin conjugating enzyme E2 L5 -2.56336
TINAGL1 tubulointerstitial nephritis antigen-like 1 -2.56336
FRMD1 FERM domain containing 1 -2.56336
VSTM2L V-set and transmembrane domain containing 2 like -2.56336
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit -2.56336
SLC5A11 solute carrier family 5 (sodium/inositol cotransporter), member 11 -2.56336
RAPSN receptor-associated protein of the synapse -2.56336
SENP1 SUMO1/sentrin specific peptidase 1 -2.56336
TRDN triadin -2.56336
BRCA2 breast cancer 2, early onset -2.56336
LRRC61 leucine rich repeat containing 61 -2.56336
AGFG2 ArfGAP with FG repeats 2 -2.56336
RASSF6 Ras association (RalGDS/AF-6) domain family member 6 -2.56336
GYS2 glycogen synthase 2 (liver) -2.56336
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 -2.56336
LPA lipoprotein, Lp(a) -2.56336
PON1 paraoxonase 1 -2.56336
SLC46A1 solute carrier family 46 (folate transporter), member 1 -2.56336
PHF10 PHD finger protein 10 -2.56336
SPRR2F small proline-rich protein 2F -2.56336
LOC114841035 uncharacterized LOC114841035 -2.56336
XKRX XK, Kell blood group complex subunit-related, X-linked -2.56336
LY6K lymphocyte antigen 6 complex, locus K -2.56336
WNT9B wingless-type MMTV integration site family, member 9B -2.56336
METAP1D methionyl aminopeptidase type 1D (mitochondrial) -2.56336
NLK nemo-like kinase -2.56336
BMI1 BMI1 proto-oncogene, polycomb ring finger -2.56336
OR2A14 olfactory receptor, family 2, subfamily A, member 14 -2.56336
COL6A6 collagen, type VI, alpha 6 -2.56336
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) -2.56336
OR2A5 olfactory receptor, family 2, subfamily A, member 5 -2.56336
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma -2.56336
PIGU phosphatidylinositol glycan anchor biosynthesis, class U -2.56336
DNAH5 dynein, axonemal, heavy chain 5 -2.56336
GLRA1 glycine receptor, alpha 1 -2.56336
HDAC7 histone deacetylase 7 -2.56336
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa -2.56336
DRD4 dopamine receptor D4 -2.56336
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 -2.56336
AURKC aurora kinase C -2.56336
CCNA1 cyclin A1 -2.56336
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -2.56336
OPTC opticin -2.56336
ITGA11 integrin, alpha 11 -2.56336
PAMR1 peptidase domain containing associated with muscle regeneration 1 -2.56336
NAP1L1 nucleosome assembly protein 1-like 1 -2.56336
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 -2.56336
C2CD4D C2 calcium-dependent domain containing 4D -2.56336
SULT1C4 sulfotransferase family, cytosolic, 1C, member 4 -2.56336
FBN1 fibrillin 1 -2.56336
GOLGA8H golgin A8 family, member H -2.56336
MUC4 mucin 4, cell surface associated -2.56336
TF transferrin -2.56336
CTSK cathepsin K -2.56336
CCDC183 coiled-coil domain containing 183 -2.56336
TSPAN16 tetraspanin 16 -2.56336
LAMP2 lysosomal-associated membrane protein 2 -2.49311
EPHA2 EPH receptor A2 -2.48321
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -2.47725
FEM1C fem-1 homolog c (C. elegans) -2.47725
ACBD5 acyl-CoA binding domain containing 5 -2.47725
DUS2 dihydrouridine synthase 2 -2.42541
MYORG myogenesis regulating glycosidase (putative) -2.41927
GNA13 guanine nucleotide binding protein (G protein), alpha 13 -2.41007
C2ORF68 chromosome 2 open reading frame 68 -2.40993
INTS14 integrator complex subunit 14 -2.39432
SPRED3 sprouty-related, EVH1 domain containing 3 -2.34932
CYTH3 cytohesin 3 -2.3359
EIF3F eukaryotic translation initiation factor 3, subunit F -2.32961
PIEZO1 piezo-type mechanosensitive ion channel component 1 -2.29806
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -2.29581
KEL Kell blood group, metallo-endopeptidase -2.27021
ELMO3 engulfment and cell motility 3 -2.25529
TIFA TRAF-interacting protein with forkhead-associated domain -2.25046
ARMC7 armadillo repeat containing 7 -2.23179
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase -2.21571
POLR1A polymerase (RNA) I polypeptide A, 194kDa -2.21571
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -2.17645
RUMY4 RUMY family member 4 -2.16537
TMEM223 transmembrane protein 223 -2.15909
DNAI1 dynein, axonemal, intermediate chain 1 -2.12257
HPSE heparanase -2.12257
SMC4 structural maintenance of chromosomes 4 -2.09589
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma -2.08049
RNPS1 RNA binding protein S1, serine-rich domain -2.06538
POGLUT2 protein O-glucosyltransferase 2 -2.05911
MCM3AP minichromosome maintenance complex component 3 associated protein -2.05285
RASA2 RAS p21 protein activator 2 -2.04818
RFC4 replication factor C (activator 1) 4, 37kDa -2.04299
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 -2.04253
NT5DC3 5'-nucleotidase domain containing 3 -2.04253
MED25 mediator complex subunit 25 -2.02395
COQ4 coenzyme Q4 -2.02235
DCHS2 dachsous cadherin-related 2 -2.02169
CIAO3 cytosolic iron-sulfur assembly component 3 -2.01166
ARPP19 cAMP-regulated phosphoprotein, 19kDa -2.01166
CCN1 cellular communication network factor 1 -2.00325