PHF3 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description PHD finger protein 3|This gene encodes a member of a PHD finger-containing gene family. This gene may function as a transcription factor and may be involved in glioblastomas development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] (NCBI Entrez Gene Database, 23469)
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Genes

327 genes differentially expressed following the PHF3 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
PNPLA1 patatin-like phospholipase domain containing 1 3.04634
IGIP IgA-inducing protein 3.04634
FOXJ1 forkhead box J1 3.04634
CTSF cathepsin F 3.04634
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 3.04634
VCX3B variable charge, X-linked 3B 3.04634
SHCBP1L SHC SH2-domain binding protein 1-like 3.04634
CCR3 chemokine (C-C motif) receptor 3 3.04634
C20ORF144 chromosome 20 open reading frame 144 3.04634
NUTM2G NUT family member 2G 3.04634
HSPB6 heat shock protein, alpha-crystallin-related, B6 3.04634
IRGM immunity-related GTPase family, M 3.04634
HMGCLL1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 3.04634
GREM2 gremlin 2, DAN family BMP antagonist 3.04634
ASB15 ankyrin repeat and SOCS box containing 15 3.04634
BTN1A1 butyrophilin, subfamily 1, member A1 3.04634
SLC26A4 solute carrier family 26 (anion exchanger), member 4 3.04634
PODNL1 podocan-like 1 3.04634
IL18R1 interleukin 18 receptor 1 3.04634
VEGFD vascular endothelial growth factor D 3.04634
CLDN34 claudin 34 3.04634
ZNF835 zinc finger protein 835 3.04634
DNAH10 dynein, axonemal, heavy chain 10 3.04634
MYO1A myosin IA 3.04634
OR2A42 olfactory receptor, family 2, subfamily A, member 42 3.04634
QRFPR pyroglutamylated RFamide peptide receptor 2.99088
TSGA13 testis specific, 13 2.97368
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 2.97368
GJB1 gap junction protein, beta 1, 32kDa 2.97368
CCL5 chemokine (C-C motif) ligand 5 2.97368
SLC25A41 solute carrier family 25, member 41 2.97368
PDZD9 PDZ domain containing 9 2.97368
SSTR1 somatostatin receptor 1 2.97368
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 2.97368
MYOM2 myomesin 2 2.97368
UNC45B unc-45 homolog B (C. elegans) 2.97368
CENPH centromere protein H 2.97368
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) 2.97368
HMX3 H6 family homeobox 3 2.97368
GALR3 galanin receptor 3 2.97368
LGALS2 lectin, galactoside-binding, soluble, 2 2.97368
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.97368
RASSF6 Ras association (RalGDS/AF-6) domain family member 6 2.97368
MUC20 mucin 20, cell surface associated 2.97368
DLL4 delta-like 4 (Drosophila) 2.97368
CPB1 carboxypeptidase B1 (tissue) 2.97368
MOGAT3 monoacylglycerol O-acyltransferase 3 2.97368
GMFG glia maturation factor, gamma 2.97368
BSX brain-specific homeobox 2.97368
SFTPB surfactant protein B 2.97368
ADGB androglobin 2.97368
ANKRD34A ankyrin repeat domain 34A 2.97368
TMEM184A transmembrane protein 184A 2.97368
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 2.97368
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 2.97368
CIROZ ciliated left-right organizer protein containing ZP-N domains 2.97368
PXDC1 PX domain containing 1 2.97368
SMCP sperm mitochondria-associated cysteine-rich protein 2.97368
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic 2.97368
MYEOV myeloma overexpressed 2.97368
ASB5 ankyrin repeat and SOCS box containing 5 2.97368
SMPX small muscle protein, X-linked 2.97368
SLC1A7 solute carrier family 1 (glutamate transporter), member 7 2.97368
C20ORF202 chromosome 20 open reading frame 202 2.97368
PDF peptide deformylase (mitochondrial) 2.97368
OTOR otoraplin 2.97368
RAG1 recombination activating gene 1 2.97368
SPATS1 spermatogenesis associated, serine-rich 1 2.97368
TMEM275 transmembrane protein 275 2.97368
CBLIF cobalamin binding intrinsic factor 2.97368
RTL9 retrotransposon Gag like 9 2.97368
CBY2 chibby family member 2 2.97368
PTH parathyroid hormone 2.97368
BLNK B-cell linker 2.97368
UCN urocortin 2.97368
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 2.97368
ZIC4 Zic family member 4 2.97368
HLX H2.0-like homeobox 2.97368
TMPRSS11F transmembrane protease, serine 11F 2.97368
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 2.97368
FPR3 formyl peptide receptor 3 2.97368
OR1R1 olfactory receptor family 1 subfamily R member 1 2.97368
ATP13A5 ATPase type 13A5 2.97368
PCDHB12 protocadherin beta 12 2.97368
ISOC2 isochorismatase domain containing 2 2.97368
SIM2 single-minded family bHLH transcription factor 2 2.97368
C1ORF162 chromosome 1 open reading frame 162 2.97368
HAPLN2 hyaluronan and proteoglycan link protein 2 2.97368
PIWIL3 piwi-like RNA-mediated gene silencing 3 2.97368
GJD2 gap junction protein, delta 2, 36kDa 2.97368
TACR2 tachykinin receptor 2 2.97368
IGBP1C IGBP1 family member C 2.97368
PSD2 pleckstrin and Sec7 domain containing 2 2.97368
MUC16 mucin 16, cell surface associated 2.97368
TESPA1 thymocyte expressed, positive selection associated 1 2.97368
SLC17A1 solute carrier family 17 (organic anion transporter), member 1 2.97368
VAV1 vav 1 guanine nucleotide exchange factor 2.97368
NT5C1B 5'-nucleotidase, cytosolic IB 2.97368
ZBP1 Z-DNA binding protein 1 2.97368
LCT lactase 2.97368
DYDC1 DPY30 domain containing 1 2.97368
APLNR apelin receptor 2.97368
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 2.97368
LRRC43 leucine rich repeat containing 43 2.97368
ACOX2 acyl-CoA oxidase 2, branched chain 2.97368
LHX2 LIM homeobox 2 2.97368
ORM2 orosomucoid 2 2.97368
PLA2G4E phospholipase A2, group IVE 2.97368
THTPA thiamine triphosphatase 2.97368
SPHKAP SPHK1 interactor, AKAP domain containing 2.97368
PDCD1LG2 programmed cell death 1 ligand 2 2.97368
AGXT2 alanine--glyoxylate aminotransferase 2 2.97368
RUMY3 RUMY family member 3 2.97368
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13 2.97368
HKDC1 hexokinase domain containing 1 2.97368
TRADD TNFRSF1A-associated via death domain 2.97368
FAM177B family with sequence similarity 177, member B 2.97368
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 2.97368
ZCCHC12 zinc finger, CCHC domain containing 12 2.97368
RAB40AL RAB40A, member RAS oncogene family-like 2.97368
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) 2.97368
SAMD7 sterile alpha motif domain containing 7 2.97368
C2ORF66 chromosome 2 open reading frame 66 2.97368
OR2V2 olfactory receptor, family 2, subfamily V, member 2 2.97368
CST1 cystatin SN 2.97368
RORC RAR-related orphan receptor C 2.97368
FAIM2 Fas apoptotic inhibitory molecule 2 2.97368
KIF4B kinesin family member 4B 2.97368
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 2.97368
SPNS3 spinster homolog 3 (Drosophila) 2.97368
TGM1 transglutaminase 1 2.97368
PPP1R3C protein phosphatase 1, regulatory subunit 3C 2.97368
PPP1R3A protein phosphatase 1, regulatory subunit 3A 2.97368
ANXA1 annexin A1 2.97368
ANGPTL5 angiopoietin-like 5 2.97368
GPRC5A G protein-coupled receptor, class C, group 5, member A 2.97368
DMRTB1 DMRT-like family B with proline-rich C-terminal, 1 2.97368
SIDT1 SID1 transmembrane family, member 1 2.97368
OR14A2 olfactory receptor, family 14, subfamily A, member 2 2.97368
ITGAD integrin, alpha D 2.97368
ZNF396 zinc finger protein 396 2.97368
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.97368
TRPM8 transient receptor potential cation channel, subfamily M, member 8 2.97368
EIF4E1B eukaryotic translation initiation factor 4E family member 1B 2.97368
LY6G6C lymphocyte antigen 6 complex, locus G6C 2.97368
RUFY4 RUN and FYVE domain containing 4 2.97368
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22 2.97368
ALOX5AP arachidonate 5-lipoxygenase-activating protein 2.97368
HPGDS hematopoietic prostaglandin D synthase 2.97368
PLGLB2 plasminogen-like B2 2.97368
GBX2 gastrulation brain homeobox 2 2.97368
POTEI POTE ankyrin domain family, member I 2.97368
PLA2G5 phospholipase A2, group V 2.97368
GH2 growth hormone 2 2.97368
LRRC24 leucine rich repeat containing 24 2.97368
APOL4 apolipoprotein L, 4 2.97368
ZPBP zona pellucida binding protein 2.97368
FGF18 fibroblast growth factor 18 2.97368
ACY1 aminoacylase 1 2.96272
CHRDL1 chordin-like 1 2.954
WSCD1 WSC domain containing 1 2.9194
CSK c-src tyrosine kinase 2.8849
CHP2 calcineurin-like EF-hand protein 2 2.8313
TMTC2 transmembrane and tetratricopeptide repeat containing 2 2.83064
SPDYE12 speedy/RINGO cell cycle regulator family member E12 2.81288
RLF rearranged L-myc fusion 2.67157
RAB9B RAB9B, member RAS oncogene family 2.65509
CEP164 centrosomal protein 164kDa 2.65297
INO80D INO80 complex subunit D 2.62238
ETF1 eukaryotic translation termination factor 1 2.60398
HAAO 3-hydroxyanthranilate 3,4-dioxygenase 2.54115
BTNL8 butyrophilin-like 8 2.51829
GCLC glutamate-cysteine ligase, catalytic subunit 2.48345
TTLL4 tubulin tyrosine ligase-like family member 4 2.46277
TP53BP2 tumor protein p53 binding protein 2 2.44611
COL25A1 collagen, type XXV, alpha 1 2.44314
PTGER4 prostaglandin E receptor 4 (subtype EP4) 2.4361
SPAG6 sperm associated antigen 6 2.40806
NLRP7 NLR family, pyrin domain containing 7 2.40806
ZMYM1 zinc finger, MYM-type 1 2.38579
N4BP3 NEDD4 binding protein 3 2.38579
ADGRF3 adhesion G protein-coupled receptor F3 2.3133
KBTBD12 kelch repeat and BTB (POZ) domain containing 12 2.3133
DHDH dihydrodiol dehydrogenase (dimeric) 2.30579
GTF2IRD1 GTF2I repeat domain containing 1 2.30579
RPA4 replication protein A4, 30kDa 2.28776
ERVH48-1 endogenous retrovirus group 48, member 1 2.26433
LHFPL4 lipoma HMGIC fusion partner-like 4 2.2424
TAS2R20 taste receptor, type 2, member 20 2.21006
SLX4 SLX4 structure-specific endonuclease subunit 2.20848
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 2.19015
RBM25 RNA binding motif protein 25 2.1686
ETV3 ets variant 3 2.12671
MAGED1 melanoma antigen family D1 2.10847
REC8 REC8 meiotic recombination protein 2.09671
CEP89 centrosomal protein 89kDa 2.08188
ERBIN erbb2 interacting protein 2.08188
MTMR6 myotubularin related protein 6 2.06057
JAK3 Janus kinase 3 2.05836
KLF13 Kruppel-like factor 13 2.0542
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 2.05124
FKBP2 FK506 binding protein 2, 13kDa 2.05028
TAGLN2 transgelin 2 2.04838
CHCHD5 coiled-coil-helix-coiled-coil-helix domain containing 5 2.04193
SIRT6 sirtuin 6 2.01732

decreased expression

Symbol Name Standardized Value
GLRB glycine receptor, beta -3.04634
SLIT1 slit homolog 1 (Drosophila) -3.04634
TMEM240 transmembrane protein 240 -3.04634
TP73 tumor protein p73 -3.04634
HRH4 histamine receptor H4 -2.97368
CCDC92 coiled-coil domain containing 92 -2.97368
TTC36 tetratricopeptide repeat domain 36 -2.97368
GOLGA6L4 golgin A6 family-like 4 -2.97368
NPAP1 nuclear pore associated protein 1 -2.97368
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 -2.97368
TRAM1L1 translocation associated membrane protein 1-like 1 -2.97368
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 -2.97368
SP100 SP100 nuclear antigen -2.97368
PRAM1 PML-RARA regulated adaptor molecule 1 -2.97368
BTN3A3 butyrophilin, subfamily 3, member A3 -2.97368
DUSP15 dual specificity phosphatase 15 -2.97368
FAM24B family with sequence similarity 24, member B -2.97368
NLRP10 NLR family, pyrin domain containing 10 -2.97368
LRRC63 leucine rich repeat containing 63 -2.97368
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit -2.97368
CCDC142 coiled-coil domain containing 142 -2.97368
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) -2.97368
METTL22 methyltransferase like 22 -2.97368
FAM110D family with sequence similarity 110, member D -2.97368
CNTNAP4 contactin associated protein-like 4 -2.97368
HGD homogentisate 1,2-dioxygenase -2.97368
RAMP3 receptor (G protein-coupled) activity modifying protein 3 -2.97368
WAS Wiskott-Aldrich syndrome -2.97368
SSUH2 ssu-2 homolog (C. elegans) -2.97368
SSC5D scavenger receptor cysteine rich family, 5 domains -2.97368
C1QTNF12 C1q and TNF related 12 -2.97368
SRA1 steroid receptor RNA activator 1 -2.97368
TEX29 testis expressed 29 -2.97368
VWA7 von Willebrand factor A domain containing 7 -2.97368
COL17A1 collagen, type XVII, alpha 1 -2.97368
PMP2 peripheral myelin protein 2 -2.97368
ILDR2 immunoglobulin-like domain containing receptor 2 -2.97368
NECTIN4 nectin cell adhesion molecule 4 -2.97368
CLDN18 claudin 18 -2.97368
OAZ3 ornithine decarboxylase antizyme 3 -2.97368
ERFE erythroferrone -2.97368
RPS21-DT RPS21 divergent transcript -2.97368
AGA-DT AGA divergent transcript -2.97368
NPIPA6 nuclear pore complex interacting protein family, member A6 -2.97368
AMIGO1 adhesion molecule with Ig-like domain 1 -2.97368
UBE2L5 ubiquitin conjugating enzyme E2 L5 -2.97368
EFCAB9 EF-hand calcium binding domain 9 -2.97368
TLR2 toll-like receptor 2 -2.97368
TRABD2B TraB domain containing 2B -2.97368
WFDC1 WAP four-disulfide core domain 1 -2.97368
SLC31A2 solute carrier family 31 (copper transporter), member 2 -2.97368
ZNF816 zinc finger protein 816 -2.96003
RAB3IL1 RAB3A interacting protein (rabin3)-like 1 -2.96003
FBXO30 F-box protein 30 -2.83906
SLBP stem-loop binding protein -2.83906
RABEP2 rabaptin, RAB GTPase binding effector protein 2 -2.82727
ADO 2-aminoethanethiol (cysteamine) dioxygenase -2.82362
RNF139 ring finger protein 139 -2.82362
EID3 EP300 interacting inhibitor of differentiation 3 -2.78925
SARAF store-operated calcium entry-associated regulatory factor -2.75502
PNMA6A paraneoplastic Ma antigen family member 6A -2.72826
SPRED3 sprouty-related, EVH1 domain containing 3 -2.72542
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 -2.61605
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 -2.61605
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa -2.60398
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 -2.54983
TIMCC TIM double twin CX3C motif chaperone -2.54115
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 -2.53596
SFXN2 sideroflexin 2 -2.51622
LIPE lipase, hormone-sensitive -2.51265
ZNF540 zinc finger protein 540 -2.4526
DNAAF5 dynein, axonemal, assembly factor 5 -2.44717
CREB3L4 cAMP responsive element binding protein 3-like 4 -2.4124
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -2.38579
SGCZ sarcoglycan, zeta -2.38579
ZNF365 zinc finger protein 365 -2.38579
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide -2.38579
CR1 complement component (3b/4b) receptor 1 (Knops blood group) -2.38579
FNIP1 folliculin interacting protein 1 -2.3331
ANKRD35 ankyrin repeat domain 35 -2.3331
DTWD1 DTW domain containing 1 -2.32946
KCNK17 potassium channel, two pore domain subfamily K, member 17 -2.3133
GZF1 GDNF-inducible zinc finger protein 1 -2.31201
SPDYE18 speedy/RINGO cell cycle regulator family member E18 -2.2964
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -2.29446
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 -2.28937
LSM8 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.28907
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.27202
SV2B synaptic vesicle glycoprotein 2B -2.26949
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 -2.26949
QPCTL glutaminyl-peptide cyclotransferase-like -2.23583
SNW1 SNW domain containing 1 -2.22112
PHLDB2 pleckstrin homology-like domain, family B, member 2 -2.21846
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase -2.20848
GPRASP1 G protein-coupled receptor associated sorting protein 1 -2.20177
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4 -2.19564
TRAF3 TNF receptor-associated factor 3 -2.19564
THBS2 thrombospondin 2 -2.17959
CES2 carboxylesterase 2 -2.15781
KRT19 keratin 19, type I -2.15343
DAXX death-domain associated protein -2.14108
BRCA1 breast cancer 1, early onset -2.12671
DLG2 discs, large homolog 2 (Drosophila) -2.12285
ENGASE endo-beta-N-acetylglucosaminidase -2.10847
ALG8 ALG8, alpha-1,3-glucosyltransferase -2.1022
SLC7A6OS solute carrier family 7, member 6 opposite strand -2.10093
KIAA1328 KIAA1328 -2.08188
GTF2IRD2 GTF2I repeat domain containing 2 -2.08188
INTS10 integrator complex subunit 10 -2.07767
PLD6 phospholipase D family, member 6 -2.06057
PDE11A phosphodiesterase 11A -2.06057
AADACL3 arylacetamide deacetylase-like 3 -2.06057
MRPS30 mitochondrial ribosomal protein S30 -2.06057
IAPP islet amyloid polypeptide -2.06057
NCAPH2 non-SMC condensin II complex, subunit H2 -2.05434
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 -2.05213
MKKS McKusick-Kaufman syndrome -2.04306
ZFAT zinc finger and AT hook domain containing -2.04306
CCT4 chaperonin containing TCP1, subunit 4 (delta) -2.04193
PDE5A phosphodiesterase 5A, cGMP-specific -2.02481
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 -2.02481
BMPR1B bone morphogenetic protein receptor, type IB -2.02445