PHF5A Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description PHD finger protein 5A|This gene encodes a subunit of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. The protein encoded by this gene contains a PHD-finger-like domain that is flanked by highly basic N- and C-termini. This protein belongs to the PHD-finger superfamily and may act as a chromatin-associated protein. This gene has several pseudogenes on different chromosomes. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 84844)
External Link https://ncbi.nlm.nih.gov/gene/84844
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Genes

498 genes differentially expressed following the PHF5A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
FABP4 fatty acid binding protein 4, adipocyte 0.0126427
ABHD4 abhydrolase domain containing 4 0.0121153
BEX1 brain expressed, X-linked 1 0.0115661
GNAS GNAS complex locus 0.0114426
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.0112172
CPE carboxypeptidase E 0.0110194
APOD apolipoprotein D 0.0110045
MYBPC1 myosin binding protein C, slow type 0.010099
SFRP1 secreted frizzled-related protein 1 0.00990714
FHL1 four and a half LIM domains 1 0.00974342
ADIPOQ adiponectin, C1Q and collagen domain containing 0.00964688
CD36 CD36 molecule (thrombospondin receptor) 0.00926119
GPRC5B G protein-coupled receptor, class C, group 5, member B 0.00897031
G0S2 G0/G1 switch 2 0.00891525
NPY1R neuropeptide Y receptor Y1 0.00887379
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00871048
CAV1 caveolin 1, caveolae protein, 22kDa 0.00862855
ZBTB18 zinc finger and BTB domain containing 18 0.00861811
SNX10 sorting nexin 10 0.00858651
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00838783
TMSB15A thymosin beta 15a 0.00835883
IRS2 insulin receptor substrate 2 0.00834404
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.0083357
PLIN1 perilipin 1 0.00827712
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.00820456
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.00818098
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 0.00810694
ZBTB35 zinc finger and BTB domain containing 35 0.00803402
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00799421
F13A1 coagulation factor XIII, A1 polypeptide 0.00796713
TPSAB1 tryptase alpha/beta 1 0.00792949
CPVL carboxypeptidase, vitellogenic-like 0.00792876
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.00782447
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00777693
CCP110 centriolar coiled coil protein 110kDa 0.00767558
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.00763924
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00762164
TM4SF4 transmembrane 4 L six family member 4 0.007581
LGALS1 lectin, galactoside-binding, soluble, 1 0.00754386
FRZB frizzled-related protein 0.00747345
TSPAN13 tetraspanin 13 0.00745483
NIBAN1 niban apoptosis regulator 1 0.00743802
CHRDL1 chordin-like 1 0.00742542
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 0.00737667
PDGFC platelet derived growth factor C 0.0073211
SOX11 SRY (sex determining region Y)-box 11 0.00728381
SYNM synemin, intermediate filament protein 0.007195
CPB1 carboxypeptidase B1 (tissue) 0.00711204
DCLK1 doublecortin-like kinase 1 0.00709449
PROM1 prominin 1 0.00704873
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.0069326
STC2 stanniocalcin 2 0.0068961
TNNT1 troponin T type 1 (skeletal, slow) 0.00685519
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.00682794
DPT dermatopontin 0.00682724
SCGB2A2 secretoglobin, family 2A, member 2 0.00680701
CFD complement factor D (adipsin) 0.00672797
SPARCL1 SPARC-like 1 (hevin) 0.00672678
RTN1 reticulon 1 0.00667798
RB1 retinoblastoma 1 0.00660555
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 0.0065974
NELL2 NEL-like 2 (chicken) 0.00658127
MEF2C myocyte enhancer factor 2C 0.00652925
TFF1 trefoil factor 1 0.00648418
PCSK6 proprotein convertase subtilisin/kexin type 6 0.00646169
AKR1C3 aldo-keto reductase family 1, member C3 0.00646076
ANXA5 annexin A5 0.00643406
OPN3 opsin 3 0.00643017
EGR2 early growth response 2 0.00637488
KRT81 keratin 81, type II 0.00637087
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.006358
TSPAN7 tetraspanin 7 0.00632898
ARHGAP29 Rho GTPase activating protein 29 0.00630142
QKI QKI, KH domain containing, RNA binding 0.00628816
ASPN asporin 0.00628253
GSTM3 glutathione S-transferase mu 3 (brain) 0.00625964
ORC1 origin recognition complex, subunit 1 0.00624243
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.00622672
PNMA8A PNMA family member 8A 0.00620541
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.00618911
NPTX2 neuronal pentraxin II 0.00615559
TTN titin 0.00615366
CTSK cathepsin K 0.00615313
CIDEC cell death-inducing DFFA-like effector c 0.00607961
CA2 carbonic anhydrase II 0.00605513
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.0059917
LMO3 LIM domain only 3 (rhombotin-like 2) 0.00598225
ACTA1 actin, alpha 1, skeletal muscle 0.00597209
GAS7 growth arrest-specific 7 0.00595075
NOVA1 neuro-oncological ventral antigen 1 0.0059245
ABAT 4-aminobutyrate aminotransferase 0.00591055
SUB1 SUB1 homolog (S. cerevisiae) 0.00588367
JAM2 junctional adhesion molecule 2 0.00588278
HMGN5 high mobility group nucleosome binding domain 5 0.00586371
COL6A2 collagen, type VI, alpha 2 0.00584613
ZNF589 zinc finger protein 589 0.00583941
PLAGL1 pleiomorphic adenoma gene-like 1 0.00583805
KLHL41 kelch-like family member 41 0.0058187
STK10 serine/threonine kinase 10 0.00581453
HHEX hematopoietically expressed homeobox 0.00581096
RTN2 reticulon 2 0.00579426
COL15A1 collagen, type XV, alpha 1 0.00578785
CES1 carboxylesterase 1 0.00577891
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00576867
TRIB3 tribbles pseudokinase 3 0.00575464
SLCO4A1 solute carrier organic anion transporter family, member 4A1 0.00575026
IL10RA interleukin 10 receptor, alpha 0.00571036
IQCK IQ motif containing K 0.00569973
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 0.00567805
HSPB8 heat shock 22kDa protein 8 0.00564185
ARMCX1 armadillo repeat containing, X-linked 1 0.00562769
C1ORF115 chromosome 1 open reading frame 115 0.00560515
ADGRG2 adhesion G protein-coupled receptor G2 0.00557659
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00557139
PJA1 praja ring finger 1, E3 ubiquitin protein ligase 0.00556614
TUBA1A tubulin, alpha 1a 0.00554785
ITM2A integral membrane protein 2A 0.00554472
CD52 CD52 molecule 0.00551593
ADCY1 adenylate cyclase 1 (brain) 0.00551066
CDCA4 cell division cycle associated 4 0.00550906
FXYD6 FXYD domain containing ion transport regulator 6 0.0054557
AGR2 anterior gradient 2 0.00544811
REEP1 receptor accessory protein 1 0.00542414
MYOT myotilin 0.00540679
DUSP5 dual specificity phosphatase 5 0.00539559
KRT19 keratin 19, type I 0.00536597
SLC38A1 solute carrier family 38, member 1 0.00534433
HK2 hexokinase 2 0.00533742
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.00530008
JCHAIN joining chain of multimeric IgA and IgM 0.00528382
SV2B synaptic vesicle glycoprotein 2B 0.00523704
ANXA4 annexin A4 0.00523053
FKBP4 FK506 binding protein 4, 59kDa 0.00523033
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 0.00522903
TPBG trophoblast glycoprotein 0.00522395
ANXA10 annexin A10 0.00520538
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00520303
CNN3 calponin 3, acidic 0.00519184
VNN1 vanin 1 0.00518105
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 0.00517765
ANGPTL2 angiopoietin-like 2 0.00513856
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle 0.00511612
RFC5 replication factor C (activator 1) 5, 36.5kDa 0.00510228
PAN2 PAN2 poly(A) specific ribonuclease subunit 0.00509753
INHBE inhibin, beta E 0.0050811
GYG2 glycogenin 2 0.00507758
CD40 CD40 molecule, TNF receptor superfamily member 5 0.00507381
EGFL6 EGF-like-domain, multiple 6 0.00505196
CKM creatine kinase, muscle 0.00504473
WBP5 WW domain binding protein 5 0.00504018
GOLM1 golgi membrane protein 1 0.00502971
GPC3 glypican 3 0.005002
PLXNC1 plexin C1 0.00498368
CCNG1 cyclin G1 0.00493399
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 0.00492159
SSPN sarcospan 0.00489544
PRELID3B PRELI domain containing 3B 0.00487875
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.00487495
PDGFRL platelet-derived growth factor receptor-like 0.00486199
TNNI1 troponin I type 1 (skeletal, slow) 0.00485817
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00485765
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.00485475
A2M alpha-2-macroglobulin 0.00485426
DDR2 discoidin domain receptor tyrosine kinase 2 0.00482201
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.00479177
CCL8 chemokine (C-C motif) ligand 8 0.00477816
DDIT3 DNA-damage-inducible transcript 3 0.00477414
FGFR2 fibroblast growth factor receptor 2 0.00477381
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.00477033
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1 0.00475322
CDO1 cysteine dioxygenase type 1 0.00475286
CCL19 chemokine (C-C motif) ligand 19 0.00474571
SYCP2 synaptonemal complex protein 2 0.00471783
PDE10A phosphodiesterase 10A 0.00471721
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 0.00470505
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.00468752
MYH2 myosin, heavy chain 2, skeletal muscle, adult 0.0046871
NBEA neurobeachin 0.00467266
PDLIM5 PDZ and LIM domain 5 0.00466862
OGN osteoglycin 0.00466672
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.00465698
MFAP2 microfibrillar-associated protein 2 0.00465515
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 0.0046515
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 0.00465121
LYZ lysozyme 0.00465008
MFAP4 microfibrillar-associated protein 4 0.00464986
PHF20 PHD finger protein 20 0.00464299
MXI1 MAX interactor 1, dimerization protein 0.00464035
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.00460486
PDE4DIP phosphodiesterase 4D interacting protein 0.00460473
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene) 0.00459926
RAB33A RAB33A, member RAS oncogene family 0.00459814
NFIB nuclear factor I/B 0.00457936
OSBPL11 oxysterol binding protein-like 11 0.00457871
SNX1 sorting nexin 1 0.00457155
FUBP1 far upstream element (FUSE) binding protein 1 0.00456575
TPD52 tumor protein D52 0.00456415
AADAC arylacetamide deacetylase 0.00455104
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.00453814
IGSF1 immunoglobulin superfamily, member 1 0.00453413
FABP7 fatty acid binding protein 7, brain 0.00452707
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 0.0045165
TSPO translocator protein (18kDa) 0.0045031
PCDH17 protocadherin 17 0.00449926
SH3BGRL SH3 domain binding glutamate-rich protein like 0.00449658
STARD13 StAR-related lipid transfer (START) domain containing 13 0.00449264
HYOU1 hypoxia up-regulated 1 0.00449211
LPAR6 lysophosphatidic acid receptor 6 0.00448853
NUP58 nucleoporin 58 0.00448305
ENO3 enolase 3 (beta, muscle) 0.0044746
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.00446803
FN1 fibronectin 1 0.00444704
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 0.00444688
HRASLS HRAS-like suppressor 0.00442395
G6PD glucose-6-phosphate dehydrogenase 0.00442179
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 0.00442075
SACS sacsin molecular chaperone 0.00441043
MAGED2 melanoma antigen family D2 0.00440865
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 0.00440864
DAXX death-domain associated protein 0.00440634
MGP matrix Gla protein 0.0044013
ANK2 ankyrin 2, neuronal 0.00439976
BID BH3 interacting domain death agonist 0.00439963
STK39 serine threonine kinase 39 0.00439521
PRSS3 protease, serine, 3 0.00439032
PMP22 peripheral myelin protein 22 0.00438024
COL5A2 collagen, type V, alpha 2 0.00437291
GBAP1 glucosidase, beta, acid pseudogene 1 0.0043572
ROPN1B rhophilin associated tail protein 1B 0.00435647
CNPY3 canopy FGF signaling regulator 3 0.00435333
ZNF217 zinc finger protein 217 0.00435082
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 0.00434759
TMED5 transmembrane emp24 protein transport domain containing 5 0.00434608
ISL1 ISL LIM homeobox 1 0.00432184
TOB1 transducer of ERBB2, 1 0.00430064
ATAD2 ATPase family, AAA domain containing 2 0.00429775
TXNIP thioredoxin interacting protein 0.00428715
CHIT1 chitinase 1 (chitotriosidase) 0.00428569
JAKMIP2 janus kinase and microtubule interacting protein 2 0.00428399
ZC3H13 zinc finger CCCH-type containing 13 0.00428031
GLS glutaminase 0.0042732
CD48 CD48 molecule 0.00427225
BBX bobby sox homolog (Drosophila) 0.00426996
SIDT2 SID1 transmembrane family, member 2 0.00426884
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.0042625
CHN2 chimerin 2 0.00425613
CRISP3 cysteine-rich secretory protein 3 0.00425297
AMOTL2 angiomotin like 2 0.00425269
H1-4 H1.4 linker histone, cluster member 0.00424984

decreased expression

Symbol Name Standardized Value
AQP3 aquaporin 3 (Gill blood group) -0.0116523
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.0106396
MMP12 matrix metallopeptidase 12 -0.0100415
CALB1 calbindin 1, 28kDa -0.00997261
TLCD3A TLC domain containing 3A -0.0096856
CEMIP cell migration inducing protein, hyaluronan binding -0.00907476
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 -0.0089672
ADI1 acireductone dioxygenase 1 -0.00876937
CLDN10 claudin 10 -0.00875058
EMX2 empty spiracles homeobox 2 -0.0087479
DIPK1A divergent protein kinase domain 1A -0.00869969
TUBB4B tubulin, beta 4B class IVb -0.00865822
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -0.00817916
SPON1 spondin 1, extracellular matrix protein -0.00816613
PRUNE2 prune homolog 2 (Drosophila) -0.00781852
BAMBI BMP and activin membrane-bound inhibitor -0.0077677
HSPA2 heat shock 70kDa protein 2 -0.00769313
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -0.00751704
TRIM22 tripartite motif containing 22 -0.00730404
MUC16 mucin 16, cell surface associated -0.00726877
PERP PERP, TP53 apoptosis effector -0.0072128
HSPB1 heat shock 27kDa protein 1 -0.00718347
FERMT1 fermitin family member 1 -0.00718087
LCN2 lipocalin 2 -0.00715911
FOLR1 folate receptor 1 (adult) -0.00700381
INHBA inhibin, beta A -0.00698646
MME membrane metallo-endopeptidase -0.00693325
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -0.00686811
S100A2 S100 calcium binding protein A2 -0.00681114
PODXL podocalyxin-like -0.00680082
SCNN1A sodium channel, non voltage gated 1 alpha subunit -0.0066446
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00662112
WNT5A wingless-type MMTV integration site family, member 5A -0.00659402
TXNDC9 thioredoxin domain containing 9 -0.00657893
RGCC regulator of cell cycle -0.00655366
NDRG1 N-myc downstream regulated 1 -0.00654323
MPZL2 myelin protein zero-like 2 -0.00650203
CD9 CD9 molecule -0.00645818
IL1R1 interleukin 1 receptor, type I -0.00641475
STEAP1 six transmembrane epithelial antigen of the prostate 1 -0.00641339
BIK BCL2-interacting killer (apoptosis-inducing) -0.00639531
TUBB3 tubulin, beta 3 class III -0.00639251
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -0.0063909
PRODH proline dehydrogenase (oxidase) 1 -0.00635483
TPM4 tropomyosin 4 -0.00633361
S100A7 S100 calcium binding protein A7 -0.00629323
KIF2C kinesin family member 2C -0.00628465
HSPA1A heat shock 70kDa protein 1A -0.00624994
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00621999
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -0.00621148
LTBP1 latent transforming growth factor beta binding protein 1 -0.00614861
MAST4 microtubule associated serine/threonine kinase family member 4 -0.00612897
ALOX5AP arachidonate 5-lipoxygenase-activating protein -0.00609086
CH25H cholesterol 25-hydroxylase -0.00608399
IFI27 interferon, alpha-inducible protein 27 -0.00606469
CFI complement factor I -0.00604056
OGDHL oxoglutarate dehydrogenase-like -0.00603807
TUBB2A tubulin, beta 2A class IIa -0.00603135
NT5E 5'-nucleotidase, ecto (CD73) -0.00602525
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 -0.00601634
FAM107A family with sequence similarity 107, member A -0.00601073
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.00598606
SELENBP1 selenium binding protein 1 -0.00597435
TSPAN12 tetraspanin 12 -0.00595399
ASRGL1 asparaginase like 1 -0.00593191
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -0.00591679
TNC tenascin C -0.00590154
KRT16 keratin 16, type I -0.00590112
EGLN3 egl-9 family hypoxia-inducible factor 3 -0.00587183
DPEP1 dipeptidase 1 (renal) -0.00585801
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) -0.00585659
KRT1 keratin 1, type II -0.00584728
BPHL biphenyl hydrolase-like (serine hydrolase) -0.00584167
HOXB6 homeobox B6 -0.00583543
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -0.00582886
SCGB2A1 secretoglobin, family 2A, member 1 -0.00582438
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.00581418
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 -0.00580382
RAB15 RAB15, member RAS oncogene family -0.00579941
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 -0.00579194
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) -0.00578875
S100A9 S100 calcium binding protein A9 -0.00578862
KLK11 kallikrein-related peptidase 11 -0.00578015
AOC1 amine oxidase, copper containing 1 -0.00576466
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 -0.00575281
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -0.00575006
IRF7 interferon regulatory factor 7 -0.00573124
CTSB cathepsin B -0.00570118
COL18A1 collagen, type XVIII, alpha 1 -0.00569765
HOXB2 homeobox B2 -0.00569538
TYRP1 tyrosinase-related protein 1 -0.00565228
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00564517
GPR137B G protein-coupled receptor 137B -0.00564477
OSBPL3 oxysterol binding protein-like 3 -0.00561512
ZNF544 zinc finger protein 544 -0.00560329
DPP4 dipeptidyl-peptidase 4 -0.00559194
AUTS2 autism susceptibility candidate 2 -0.00558264
S100A8 S100 calcium binding protein A8 -0.00554229
MDK midkine (neurite growth-promoting factor 2) -0.0055312
F2RL1 coagulation factor II (thrombin) receptor-like 1 -0.00549429
TBX2 T-box 2 -0.00548682
IFI35 interferon-induced protein 35 -0.00548633
IFRD2 interferon-related developmental regulator 2 -0.00548615
VSNL1 visinin-like 1 -0.00545678
CLCA2 chloride channel accessory 2 -0.00545546
RNF167 ring finger protein 167 -0.00544743
KLK6 kallikrein-related peptidase 6 -0.00541823
MVP major vault protein -0.00540002
UBE2S ubiquitin-conjugating enzyme E2S -0.0053627
KLK8 kallikrein-related peptidase 8 -0.0053544
HLA-B major histocompatibility complex, class I, B -0.0053535
PHLDA2 pleckstrin homology-like domain, family A, member 2 -0.00535206
ALCAM activated leukocyte cell adhesion molecule -0.0053509
LYPD1 LY6/PLAUR domain containing 1 -0.00534488
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F -0.00533476
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.00533164
NNMT nicotinamide N-methyltransferase -0.00532759
LBH limb bud and heart development -0.00531846
AK1 adenylate kinase 1 -0.00528557
EIF5 eukaryotic translation initiation factor 5 -0.00528516
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C -0.00527866
MAL mal, T-cell differentiation protein -0.00525518
TMPRSS4 transmembrane protease, serine 4 -0.0052361
EYA2 EYA transcriptional coactivator and phosphatase 2 -0.00522953
KLK10 kallikrein-related peptidase 10 -0.00521512
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain -0.0051977
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -0.00518053
PAEP progestagen-associated endometrial protein -0.00515851
HCLS1 hematopoietic cell-specific Lyn substrate 1 -0.00513212
C1RL complement component 1, r subcomponent-like -0.00512392
VAMP8 vesicle-associated membrane protein 8 -0.00509228
BTF3P11 basic transcription factor 3 pseudogene 11 -0.00508955
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -0.0050824
RNASET2 ribonuclease T2 -0.00507478
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -0.00507014
LYPD3 LY6/PLAUR domain containing 3 -0.0050547
ENG endoglin -0.00505355
DEFB1 defensin, beta 1 -0.00505056
MIPEP mitochondrial intermediate peptidase -0.00503924
CA12 carbonic anhydrase XII -0.0050034
NARF nuclear prelamin A recognition factor -0.00498824
PRPF4 pre-mRNA processing factor 4 -0.00498418
OXA1L oxidase (cytochrome c) assembly 1-like -0.00498233
QPCT glutaminyl-peptide cyclotransferase -0.00496748
BGN biglycan -0.00495818
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 -0.00494484
ACOX2 acyl-CoA oxidase 2, branched chain -0.00494019
TPI1 triosephosphate isomerase 1 -0.00493491
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.00493342
KLK7 kallikrein-related peptidase 7 -0.00493141
FHOD3 formin homology 2 domain containing 3 -0.00491322
ACAA1 acetyl-CoA acyltransferase 1 -0.00488544
SH3YL1 SH3 and SYLF domain containing 1 -0.00488117
HIST3H2A histone cluster 3, H2a -0.00487785
ZNF205 zinc finger protein 205 -0.00487567
ISG15 ISG15 ubiquitin-like modifier -0.00484816
PLAT plasminogen activator, tissue -0.00484669
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 -0.00481497
NDRG4 NDRG family member 4 -0.00481267
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) -0.0048096
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.00480375
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -0.00480265
HDAC9 histone deacetylase 9 -0.00478235
COL7A1 collagen, type VII, alpha 1 -0.0047757
PGAM1 phosphoglycerate mutase 1 (brain) -0.00477115
MSRB1 methionine sulfoxide reductase B1 -0.00476962
ECM1 extracellular matrix protein 1 -0.00476468
SATB2 SATB homeobox 2 -0.00475752
SULF1 sulfatase 1 -0.00474336
CD38 CD38 molecule -0.00473295
C9ORF3 chromosome 9 open reading frame 3 -0.00472922
WFDC2 WAP four-disulfide core domain 2 -0.00472503
KRT13 keratin 13, type I -0.00471853
CD59 CD59 molecule, complement regulatory protein -0.0047184
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -0.00471617
LY6D lymphocyte antigen 6 complex, locus D -0.00471443
EPHB4 EPH receptor B4 -0.00468673
EAF2 ELL associated factor 2 -0.00468651
IGFBP6 insulin-like growth factor binding protein 6 -0.00468119
UXS1 UDP-glucuronate decarboxylase 1 -0.00466872
MZB1 marginal zone B and B1 cell-specific protein -0.00465839
ISG20 interferon stimulated exonuclease gene 20kDa -0.00465307
ZNF586 zinc finger protein 586 -0.00465024
IFIH1 interferon induced with helicase C domain 1 -0.00462671
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00462393
KRT6A keratin 6A, type II -0.00462375
TMEM243 transmembrane protein 243, mitochondrial -0.004622
BHMT betaine--homocysteine S-methyltransferase -0.00460337
PDZK1IP1 PDZK1 interacting protein 1 -0.00458736
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -0.00458521
SPRY4 sprouty homolog 4 (Drosophila) -0.00458463
CCNF cyclin F -0.0045568
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.0045542
CRYM crystallin, mu -0.00454908
TTC38 tetratricopeptide repeat domain 38 -0.0045468
CST7 cystatin F (leukocystatin) -0.00454154
PUF60 poly-U binding splicing factor 60KDa -0.00454055
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00453605
MARCKSL1 MARCKS-like 1 -0.00453499
XPO7 exportin 7 -0.00452972
GUCY2C guanylate cyclase 2C -0.00452806
GP1BB glycoprotein Ib (platelet), beta polypeptide -0.00452214
PLK1 polo-like kinase 1 -0.00450097
BSPRY B-box and SPRY domain containing -0.00449252
SRGN serglycin -0.00448299
ANO10 anoctamin 10 -0.00448074
CXADR coxsackie virus and adenovirus receptor -0.00447818
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -0.00447701
TPM2 tropomyosin 2 (beta) -0.00447134
MAP3K6 mitogen-activated protein kinase kinase kinase 6 -0.00446718
AHNAK2 AHNAK nucleoprotein 2 -0.00445764
MMP10 matrix metallopeptidase 10 -0.00445696
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00445357
SUGCT succinyl-CoA:glutarate-CoA transferase -0.00443891
EIF4A3 eukaryotic translation initiation factor 4A3 -0.00443775
POF1B premature ovarian failure, 1B -0.00443291
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3 -0.00443053
VAMP5 vesicle-associated membrane protein 5 -0.0044236
RHOB ras homolog family member B -0.00441602
TACSTD2 tumor-associated calcium signal transducer 2 -0.00439875
USP18 ubiquitin specific peptidase 18 -0.0043966
NOP56 NOP56 ribonucleoprotein -0.00438786
LAMP3 lysosomal-associated membrane protein 3 -0.00438242
GSTT1 glutathione S-transferase theta 1 -0.00437325
TSC22D3 TSC22 domain family, member 3 -0.00436509
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome -0.00436318
CYB5A cytochrome b5 type A (microsomal) -0.00434629
COPS7A COP9 signalosome subunit 7A -0.00432175
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -0.00431609
RIMBP2 RIMS binding protein 2 -0.00431478
TM7SF2 transmembrane 7 superfamily member 2 -0.00430608
HOXC10 homeobox C10 -0.00430276
VCAM1 vascular cell adhesion molecule 1 -0.0043018
PTGES2 prostaglandin E synthase 2 -0.00429585
GARS1 glycyl-tRNA synthetase 1 -0.00428747
MRPL28 mitochondrial ribosomal protein L28 -0.00427034
IFITM2 interferon induced transmembrane protein 2 -0.0042684
CDK18 cyclin-dependent kinase 18 -0.00426146
MRPL12 mitochondrial ribosomal protein L12 -0.00425982
KLF6 Kruppel-like factor 6 -0.00425413
RIPK4 receptor-interacting serine-threonine kinase 4 -0.00423927
C9ORF16 chromosome 9 open reading frame 16 -0.0042134
GIPC1 GIPC PDZ domain containing family, member 1 -0.0042114
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 -0.00421106
MAP7 microtubule-associated protein 7 -0.00420563
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 -0.00419386
CDH2 cadherin 2, type 1, N-cadherin (neuronal) -0.00419364
QPRT quinolinate phosphoribosyltransferase -0.00419135
FSCN1 fascin actin-bundling protein 1 -0.0041879