PHF8 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description PHD finger protein 8|The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. Defects in this gene are a cause of mental retardation syndromic X-linked Siderius type (MRXSSD). Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010] (NCBI Entrez Gene Database, 23133)
External Link http://www.ncbi.nlm.nih.gov/gene/23133
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Genes

60 interacting proteins for PHF8 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ANAPC1 anaphase promoting complex subunit 1
ANAPC2 anaphase promoting complex subunit 2
ANAPC4 anaphase promoting complex subunit 4
ANAPC5 anaphase promoting complex subunit 5
ANAPC7 anaphase promoting complex subunit 7
APP amyloid beta (A4) precursor protein
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
BPTF bromodomain PHD finger transcription factor
CCNB1 cyclin B1
CDC16 cell division cycle 16
CDC20 cell division cycle 20
CDC23 cell division cycle 23
CDC26 cell division cycle 26
CDC27 cell division cycle 27
CDK1 cyclin-dependent kinase 1
CHD1 chromodomain helicase DNA binding protein 1
CHEK1 checkpoint kinase 1
E2F1 E2F transcription factor 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
HCFC1 host cell factor C1
HIST1H3B histone cluster 1, H3b
HIST1H4F histone cluster 1, H4f
HIST2H3A histone cluster 2, H3a
HIST3H3 histone cluster 3, H3
ING1 inhibitor of growth family, member 1
ING2 inhibitor of growth family, member 2
KDM5A lysine (K)-specific demethylase 5A
MAML1 mastermind-like 1 (Drosophila)
NCOR2 nuclear receptor corepressor 2
NOTCH1 notch 1
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
RARA retinoic acid receptor, alpha
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RPAP1 RNA polymerase II associated protein 1
SETD1A SET domain containing 1A
SETD8 SET domain containing (lysine methyltransferase) 8
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TBP TATA box binding protein
UBC ubiquitin C
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
WDR5 WD repeat domain 5
ZNF711 zinc finger protein 711